• Journal of Navigation and Port Research
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• v.29 no.5 s.101
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• pp.447-455
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• 2005

Intra-block remarshalling is the task of rearranging into some target bays those containers which are scattered within around the block. If multiple transfer cranes installed in the block are all used together we may be able to complete the remarshalling task as early as possible. However, when multiple cranes are used simultaneously, there may occur significant delays if we do not carefully consider interferences between the cranes at the time of scheduling. Especially, delays caused by interferences occur more frequently in case of using non-crossing cranes. This paper presents an efficient heuristic method for assigning moves of containers to each crane and for determining an appropriate container moving order in a manner sensitive to the interferences. Simulation experiments have shown that the proposed method can effectively reduce delays in various environments.

• Journal of Life Science
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• v.27 no.4
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• pp.423-429
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• 2017

Hair color is determined by kind and amount of melanin. Melanocyte mainly synthesizes melanin from L-tyrosine by stimulation of ultra violet. Reactive oxygen species (ROS) play an important role in greying hair. Polygonum multiflorum radix has been reported to inhibit the aging process that black color of hair is turned into grey color. The aim of this study is to investigate the effect of Polygoni multiflorium radix ethanol extract (PMEE) on melanin synthesis related to black hair growth. In anti-oxidant experiment, PMEE decreased DPPH radical and increased reducing power, indicating that PMEE could eliminate ROS involved in greying hair. PMEE decreased cell viability in a dose-dependent manner. Furthermore, the effect of PMEE on the production of melanin was determined by DOPA assay and tyrosinase activity. PMEE increased tyrosinase activity and promoted melanin synthesis. In addition, the expression levels of tyrosinase, tyrosinase related protein-1 (TRP-1), tyrosinase related protein-2 (TRP-2) and microphthalmia-associated transcription factor (MITF), as well as anti-oxidant enzymes such as superoxide dismutase (SOD-3) and catalase were examined using western blot analysis. The expression levels of SOD-3 and catalase were decreased due to the enhanced antioxidant activity of PMEE. In particular, PMEE increased the expression levels of tyrosinase and TRP-2. These results suggest that PMEE could promote melanin synthesis that involved in tuning gray hair into black hair.

• Journal of Intelligence and Information Systems
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• v.13 no.1
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• pp.49-58
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• 2007

MDPDPTW (Multi-Depot Pickup and Delivery Problem with Time Windows) is a typical model among the optimization models based on the pickup and delivery flow in supply chains. It is based on multi-vehicles in multi-depots and does not consider moving vehicles near pickup and delivery locations. In ubiquitous environments, it is possible to obtain information on moving vehicles and their baggage. Providing the proper context from the perspective of moving vehicles and their baggage allows for more effective vehicle routings. This study proposes Integer Programming-based MDPDPTW including the information on moving vehicles and their baggage in a ubiquitous environment: u-MDPDPTW, and shows the viability and effectiveness of u-MDPDPTW through comparative experiments of MDPDPTW and u-MDPDPTW.

• Applied Biological Chemistry
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• v.28 no.4
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• pp.271-277
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• 1985

A polarograph with specially designed cell compartment usable in kinetic study of the mitochondrial respiration of a small sized sample was made, and its performance and experimental conditions were examined. An applied potential (ca-1.2V vs. SCE) which gives rise to the second step reduction of oxygen caused a considerable level of a residual current independent of oxygen, which is temporarily interpreted as the reduction current of the membrane-bound redox material(s) of mitochondria. A potential corresponding to the first slop reduction of oxygen (ca-0.4V vs SCE) did not produce the residual current. Thus, it is suggested that a measurement of oxygen concentration in a sample of mitochondria and submitochondrial particles by using dropping mercury electrode should be done with an applied potential of about -0.4V vs SCE. Consumption of oxygen by mitochondria was observed to follow practically zero order kinetics. Its rate constant exhibited the proportional relationship with the respiratory activity of mitochondria. Usefulness of tile instrument was properly demonstrated in the work on the temperature effect on the respiration of mitochondria isolated from several plant 4issues which were selected on the basis of chilling susceptivity.

• Proceedings of the KAIS Fall Conference
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• 2010.11b
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• pp.595-598
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• 2010

본 연구의 목적은 뇌졸중으로 인한 만성 편마비 환자를 대상으로 발에 시지각 자극을 적용하여 균형과 보행에 관한 운동기능에 미치는 효과를 알아보고자 하였다. 6개월 이상 된 편마비 환자 16명이 연구에 참여하였고, 무작위로 실험군(EG) 10명과 대조군(CG) 10명으로 구분하였다. 두 군 모두 기본적인 물리치료를 적용하였고 실험군은 정적균형도구인 Tetrax Multiple System을 이용하여 발목에 감각되먹임 시지각 자극을 매회 30분, 4주간 주 3회 실시하였다. 운동 중재 전과 후의 운동기능에 해당하는 균형(TUG), 보행(DGI)을 측적하여 본 연구의 효과를 비교하였다. 실험군에서 정적 균형, TUG, 그리고 동적 균형지수(DGI) 지수는 중재 전후 통계적으로 유의한 차이를 나타냈고(p<.05), 실험, 대조군간 전후의 변화율에서도 유의한 차이가 나타났다(p<.05). 대조군에서는 DGI 만 중재 전후 통계적으로 유의한 차이가 나타났다. 순수하게 유산소 운동만을 실시하였다. 통계처리 방법으로 전 후 차이를 검증하기 위하여 대응표본 t 검정을 실시하였고 대조군과의 차이 검증을 위하여 독립표본 t 검정을 실시하였다. 모든 통계적 유의수준은 0.05로 하였다. 본 연구에서는 편마비 환자에게 흥미를 촉진하고 운동 기능 회복의 효과를 강화할 수 있는 감각 되먹임이 동반된 시지각 자극을 적용하여 균형 및 보행기능의 향상을 얻을 수 있었고, 차후 연구는 장기간의 추적 관찰 연구가 지속되어야 하고 발목 뿐만 아니라 다른 관절에서의 비교연구가 필요할 것이다.

• 한국약용작물학회:학술대회논문집
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• 2011.09a
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• pp.158-159
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• 2011

• Journal of the Korean Society of Marine Environment & Safety
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• v.14 no.2
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• pp.145-148
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• 2008

Cationic surfactant can be used as cosmetics and chemical dispersants. The variation of critical micelle concentration (CMC) with temperature over the range $40^{\circ}C$ to $60^{\circ}C$ for N-octadecyl pyridinium bromide was measured by drop methods. Thermodynamic quantities such as free energy, enthalpy, entropy and heat capacity for micellization of N-octadecyl pyridinium bromide in water were calculated by fourth-degree polynominal equation In the result, free energy change was decreased generally by the increment of temperature.

• Journal of the Korean Society of Food Science and Nutrition
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• v.38 no.1
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• pp.32-38
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• 2009

In this study, we investigated the anti-obesity activity of the herbal extract mixture (HEM). The inhibitory effect of HEM on triglyceride accumulation of 3T3-L1 preadipocyte was examined by Oil-Red O staining. HEM inhibited the triglyceride accumulation of 3T3-L1 preadipocyte cell and reduced glycerol-3-phosphate dehydrogenase (GPDH) activity. We further investigated the effect of HEM in prevention of obesity in male ICR mouse for 5 weeks. Experimental groups were divided into high fat diet group (HFD), HFD supplemented with 100 mg/kg HEM group (HEM1) and HFD supplemented with 200 mg/kg HEM group (HEM2). Body weight and food efficiency ration of HEM1 and HEM2 was decreased by 52% and 50% and by 45% and 50%, respectively. The amount of adipocyte in body weight was decreased. Blood triglyceride and total cholesterol of HEM1 was significantly decreased. These results indicate that HEM may be useful in preventing obesity.

• Proceedings of the Korean Institute of Navigation and Port Research Conference
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• 2004.11a
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• pp.203-208
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• 2004

The objective of this study is to analyze the efficiency of marshalling work using ATC(automated transfer crane) for ACT(automated container terminal). It is important fact to assignment of containers, because the character of ACT which block layout is vertical for berth and there are four other works which are inbound, oubound, loading and unloading in one block. And then there is need which assignment of containers with remarshaling work using ATCs in one block. Therefore, we analyze the efficiency of remarshaling work using simulation and suggest the assignment methodology of containers in yard

• Journal of ILASS-Korea
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• v.10 no.2
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• pp.18-31
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• 2005

This study was performed to explore the liquid breakup and atomization characteristics for the classification of drop formation mode and background of uniform droplets generation in electrohydrodynmaic atomization according to the change of experimental parameters such as nozzle material (stainless steel. teflon). fluid flow rate, applied electrical field and intensity, and frequency. In results, from the classification map of drop formation modes according to the variation of applied AC voltage and frequency at a stainless nozzle, the droplet size was smaller than the outer diameter of the nozzle tip relatively in the spindle mode. The transition points became clearly to be moved toward the high applied voltage by rising the applied AC frequency beyond 450Hz. Also the droplet radius can be observed quite small in the frequency bandwidth of $350{\sim}450Hz$. The droplet radiuses decrease as the applied voltage increases for a fixed applied AC frequency within the range from 50Hz to 400Hz Over 400Hz, the relation between the power intensity and the droplet size was not consistent with a continuous mechanism of liquid breakup. Thus, it is showed that the droplet size distribution using the teflon nozzle was analogous to the results of stainless steel, but the droplet size was bigger than that of stainless steel relatively in case of a teflon nozzle.