• Title/Summary/Keyword: 저밀도 지단백

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Gender Difference in Associations between Serum Cholesterol Levels and Depression Symptoms in Healthy General Population (건강한 성인에서 성별에 따른 혈중 콜레스테롤 농도와 우울증상의 연관성 : 후향적 의무기록 조사)

  • Lee, So Hee;Park, Mina;Yoon, Dae Hyun;Lee, Young;Kim, Sun Shin
    • Korean Journal of Psychosomatic Medicine
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    • v.25 no.1
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    • pp.27-32
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    • 2017
  • Objectives : The purpose of this study was to determine the association between serum lipid profiles and depression according to gender difference. Methods : This retrospective cohort study included 27,452 subjects(15044 men and 12408 women) who underwent health examination. The duration was from January 2013 to December 2013. We estimate the correlation between serum lipid profile and Beck Depression Inventory(BDI) scores. We compare the effect size using beta coefficient. Results : In men, serum Triglyceride level was correlated positively with BDI scores(r=0.020, p<0.01). Serum LDL-C and HDL-C were negatively correlated with BDI scores(r=-0.015, p<0.01 ; r=-0.016, p<0.05). In women, Triglyceride level was also correlated positively with BDI scores(r=0.020, p<0.01), Serum HDL-C were negatively correlated with BDI scores(r=-0.019, p<0.01). There was no statistical significance between Serum LDL-C and Beck Depression Inventory(BDI) score. Conclusions : Both men and women had more depressive symptoms when they had low serum HDL-C level or high serum Triglyceride level. The depression symptoms were more severe when serum LDL-C level was low only in men.

Assessment of the Optimum LDL : HDL-cholesterol(LDL : HDL-C) Ratio for Predicting CHD (심혈관질환 예측을 위한 저밀도 대 고밀도 지단백 콜레스테롤 비(LDL : HDL-cholesterol ratio)의 적정기준에 관한 연구)

  • Yeoum, Soon-Gyo
    • Korean Journal of Adult Nursing
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    • v.20 no.6
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    • pp.917-931
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    • 2008
  • Purpose: This study was aimed to determine the optimum low-density lipoprotein : high-density lipoprotein-cholesterol (LDL : HDL-C) ratio for predicting coronary heart disease(CHD) in Korean people. Methods: It was analyzed this data of 5,431 adults who had undergone health examinations in a hospital in Gyeonggi-do between January 2006 and December 2007. The covariation of the coronary risk factors such as age, HbA1C, systolic blood pressure(SBP), and waist-to-stature ratio(WSR) were analyzed by using logistic regression analysis. Results: The LDL : HDL-C ratio in the male and female groups was mostly distributed between 1.5 and 4.0. The LDL : HDL-C ratio was the most significant cholesterol-related parameter influencing CHD (male: B = .306, p = .054, female : B = .940, p = .010), followed by LDL-C and total cholesterol. It was observed a sharp increase in the odds ratios for LDL : HDL-C ratios of 2.25 - 2.50(male) and 2.00 - 2.25(female). A significant difference was observed in both male(2.25 : $x^2$ = 2.494, p = .072) and female(2.00 : $x^2$ = 413.742, p = .000) groups. Conclusion: The risk level of CHD was set to 2.25 for males and 2.00 for females. Therefore, the optimum LDL : HDL-C ratio for Koreans should be far lower than that for the people in western countries.

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Relationship of Body Fat Percent with Serum Lipid Level and Blood Pressure in Adults (Impedance Fat Meter로 측정한 체지방 비율과 혈청 지질치 및 혈압과의 관련성)

  • Lee, Seock-Whan;Hwang, Tae-Yoon;Kim, Chang-Yoon
    • Journal of Preventive Medicine and Public Health
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    • v.28 no.4 s.51
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    • pp.783-794
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    • 1995
  • This study was conducted to clarify the relationship of body fat percent with serum lipid level and blood pressure in adults. The study subjects were 472 men and 189 women who visited Multiphasic Health Screening Center of Yeungnam University Hospital in Taegu from May 20 to September 30, 1994. The relationship of serum lipid and blood pressure with BMI, Katsura index, atherogenic index, which calculated from the health screening data and body fat percent measured by impedance fat meter(model SIF-819) were analyzed. Three groups were classified as Group I (men : body fat Percent $\geq$ 20, women : body fat percent $\geq$ 25), Group II (men : 15 $\leq$ body fat percent< 20, women : 20 $\leq$ body fat percent< 25), Group III(men : body fat percent < 15, women body fat percent <20). In this study, Group I accounted for 3.2% in men, 3.7% in women. Weight was significantly different among three groups in both sexes(p<0.01) and height was not significantly different among three groups. In men, serum total cholesterol, triglyceride, high density lipoprotein, low density lipoprotein, atherogenic index were significantly different(p<0.01). In women, serum total cholesterol and low density lipoprotein were significantly different(p<0.05) but there was no differences in triglyceride and high density lipoprotein among three groups. BMI and Katsura index were significantly different among three groups in both sexes(p<0.01). In men, body fat percent was positively correlated with weight, BMI, Katsura index, total cholesterol, triglyceride, low density lipoprotein, atherogenic index and systolic and diastolic blood pressures, and negatively correlated with high density lipoprotein. In women, body fat percent was positively correlated with age, height, weight, BMI, Katsura index, total cholesterol, triglyceride, low density lipoprotein and atherogenic index, and negatively correlated with high density lipoprotein. But there was no significant correlation between body fat percent and blood pressure in women. In multiple regression analysis for total cholesterol, fat percent, age and BMI were significant independent variables in men$(p<0.05,\;R^2=0.1286)$, and body fat percent and age in women$(p<0.05,\;R^2=0.3399)$. In case of LDL/HDL ratio, only BMI was a significant independent variable in menu$(p<0.01,\;R^2=0.0954)$, and body fat percent, age and BMI in women$(p<0.05,\;R^2=0.3164)$. In multiple regression analysis, age, low density lipoprotein and total cholesterol were significant independent variables on systolic blood pressure in men$(p<0.05,\;R^2=0.1297)$, age and total cholesterol in women$(p<0.05,\;R^2=0.1705)$. On diastolic blood pressure, only age was a significantly independent variable in men$(p<0.01,\;R^2=0.0972)$ and women$(p<0.01,\;R^2=0.1218)$. From the result of this study, it could concluded that body fat percent was significantly associated with other obesity indices and serum lipid, but had no significant association with blood pressure. To establish the relationship of body fat percent with blood pressure, further study which consider other variables that may have an effect on blood pressure should be performed.

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Analysis of the Relationship between Abdominal Ultrasound Based Kidney Stones, Obesity and Metabolic Syndrome (복부 초음파 검사 기반 신장결석과 비만 및 대사증후군 관련성 분석)

  • Kim, Ju Hee;Jang, Hyon Chol;Cho, Pyong Kon
    • Journal of the Korean Society of Radiology
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    • v.14 no.4
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    • pp.495-502
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    • 2020
  • Kidney stones are a common disease with an annual prevalence of about 30,000 people in Korea, and are deeply related to an increase in chronic kidney disease, high blood pressure, coronary artery disease, metabolic syndrome, type 2 diabetes, hyperlipidemia, and abdominal obesity. Therefore, in this study, 135 examinees who visited a general hospital in Dalseong-gun from May 2019 to June 2020 for a medical examination were examined. The relationship between kidney stones and factors related to obesity and metabolic syndrome were found in abdominal ultrasound. I tried to find out the relevance. As a result of the study, the risk of kidney stones in the abnormal group was increased by 4.255 times compared to the normal group in total cholesterol factor, and the risk of kidney stones in the abnormal group was increased by 2.072 times compared to the normal group in the low-density lipoprotein cholesterol factor. Total cholesterol factor and low-density lipoprotein cholesterol It was found that the factor affects the prevalence of kidney stones and metabolic syndrome. Since the risk of kidney stones is related to total cholesterol and low-density lipoprotein cholesterol factors, active attention should be paid to preventive purposes through health check-ups.

Effect of Catechins on Serum Lipids in Obese Women (카테킨 음용이 비만여성의 혈중 지질농도에 미치는 영향)

  • Choi, Won-Ho;Lee, Jung-Won
    • The Journal of the Korea Contents Association
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    • v.12 no.1
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    • pp.338-345
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    • 2012
  • This study was developed to test the effectiveness catechin beverage drinking as exercise supplementary food for obese women. The effects of catekin were determined by weight, total cholesterol, triglycerides, High density lipoprotein cholesterol, high density lipoprotein cholesterol. Twenty-seven obese women were participated in this study. Eight women were tea catechin drinking group, Nine women were exercise group, and ten women were tea catekin drinking-combined with exercise group. After catechin drinking or exercise conducted, blood lipid factor were analyzed. body weight and triglycerides low density lipoprotein cholesterol levels were significantly decreased in tea catekin drinking combined with exercise group (p<0.001) and exercise group (p<0.001). total cholesterol were significantly decreased in three groups (p<0.05). It is thought that together catechin drinking and exercise can maximize weight loss of obese woman and reducing of blood lipid factor.

Risk Factors of Non-alcoholic Steatohepatitis in Childhood Obesity (비만아에서 비알코올성 지방간염의 위험요인)

  • Yun, Eun-Sil;Park, Yong-Hun;Choi, Kwang-Hae
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • v.10 no.2
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    • pp.179-184
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    • 2007
  • Purpose: Obesity has recently emerged as a significant health problem in the pediatric population, and the prevalence of non-alcoholic fatty liver disease is increasing in tandem with a significant rise in childhood obesity. Therefore, this study was conducted to clarify the risk factors of non-alcoholic steatohepatitis in obese children. Methods: We enrolled 84 obese children who visited the pediatric obesity clinic at Yeung-Nam university hospital. The patients were divided into two groups based on their alanine aminotransferase (ALT) level (separated at 40 IU/L), and the mean of ages, total cholesterol levels, HDL-cholesterol levels, LDL-cholesterol levels, triglyceride (TG) levels, as well as the mean obesity index, and body fat percentage of the two groups were then compared. Results: When the mean of ages ($10.5{\pm}1.6$ vs. $10.7{\pm}2.0$ years), total cholesterol levels ($183.0{\pm}29.1$ vs. $183.7{\pm}31.3$ mg/dL), HDL-cholesterol levels ($53.0{\pm}10.2$ vs. $55.7{\pm}13.0$ mg/dL), LDL-cholesterol levels ($113.4{\pm}30.2$ vs. $113.0{\pm}30.0$ mg/dL), triglyceride levels ($99.4{\pm}62.9$ vs. $114.2{\pm}47.3$ mg/dL), obesity indexes ($44.7{\pm}12.2$ vs. $47.9{\pm}15.1%$), and body fat percentages ($32.7{\pm}5.0$ vs. $34.0{\pm}4.8%$) of group 1 (ALT${\leq}$40 IU/L) were compared with those of group 2 (ALT${\geq}$41 IU/L), no significant differences were observed (p>0.05). However, hypertriglyceridemia (TG${\geq}$110 mg/dL) was more frequent in group 2 than in group 1 (p=0.023). Conclusion: TG may be an important risk factor in non-alcoholic steatohepatitis and further study regarding the risk factors in non-alcoholic steatohepatitis is required.

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The Study of Blood metabolic Variation on 10Km Horseback Riding and Running (10km 승마운동과 달리기 운동 시 혈중 대사 변화 연구)

  • Nam, Sang-Nam;Park, Jeong-Bum
    • Journal of the Korea Convergence Society
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    • v.9 no.4
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    • pp.381-386
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    • 2018
  • This study aims to provide a scientific proof of the effects of horseback riding sports by analyzing changes in metabolic variation of horseback riding and running before and after 10km running. Paired t-test and independent t-test were conducted to process the data. The results show that among lipid source glucose significantly increases for horseback riding group $97.78{\pm}14.55mg/dl$ to $123.21{\pm}33.88mg/dl$, (p<.05). TC horseback riding group $188.71{\pm}35.25mg/dl$ to $199.35{\pm}32.79mg/dl$(p<.01), LDL-C also significant increases in riding group $113.42{\pm}33.39mg/dl$ to $121.42{\pm}32.52mg/dl$(p<.01). HDL-C also shows significant increase; in riding group $53.42{\pm}14.36mg/dl$ to $56.64{\pm}15.24mg/dl$(p<.01). show that among lipid variation glucose significantly change in horseback riding group, TC horseback riding group, LDL-C also change in riding group.

Effect of Dance Sports Participation in Obesity Middle-Women on Body Composition and Blood Lipids: Meta-Analysis (비만 중년여성의 댄스스포츠 참여가 신체조성과 혈중지질에 미치는 효과: 메타분석)

  • NARUSE, MASAYO;An, Ki-Yong;Jeon, Justin Y
    • 한국체육학회지인문사회과학편
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    • v.55 no.3
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    • pp.613-626
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    • 2016
  • The purpose of this study was to identify the effect of dance sport participation on body composition and cardiometabolic parameters in obese middle aged women, by analyzing the current literature(2005-2015). The data from 9 studies were included in this systematic review and meta-analysis, and Comprehensive Meta Analysis(CMA) Version 2.0 was used for statistical analysis. A total of 197 middle aged women(intervention group: n=98, control group: n=99) were included in this analysis. An average duration of the dance sports intervention was 12.2 weeks, 3.13 session per week and 75 minutes per session. Significant reduction in body weight, body fat percent, triglyceride, low density lipoprotein LDL-Cholesterol and leptin were observed while significant increase in high density lipoprotein HDL-cholesterol was observed after the intervention. There were large effect size in percent body fat, total cholesterol, HDL-cholesterol and LDL-cholesterol while medium and small effect size were observed for triglyceride and body weight, leptin, insulin and glucose, respectively. In conclusion, dance sport participation resulted in positive changes in body composition and cardiometabolic parameter in middle aged women.

Efficacy of Acipimox in Comparison with Fenofibrate for Hypertriglyceridemia (고중성지방혈증에서 fenofibrate에 대한 acipimox의 효과 비교)

  • Kim, Seung Mi;Ji, Eunhee;Kim, Hyunah;Han, Nayoung;Shim, Mikyung;Shin, Wan Gyoon;Oh, Jung Mi
    • Korean Journal of Clinical Pharmacy
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    • v.22 no.3
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    • pp.195-201
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    • 2012
  • 목적: 이상지방혈증 환자의 치료는 우선적으로 저밀도지단백을 감소시키고, 저밀도지단백이 목표수치에 도달한 이후에도 혈중 중성지방이 높을 경우 nicotinic acid 또는 fibrate를 사용하도록 권장되고 있다. 본 연구는 이상지방혈증이 있는 환자에서 acipimox의 효과를 fenofibrate와 비교하여 분석하고자 시행되었다. 방법: 본 연구는 서울에 있는 한 3차 대학병원의 환자를 대상으로 후향적으로 의무기록을 분석하여 시행되었다. 혈중 중성지방 농도가 200 mg/dL 이상으로써 acipimox 또는 fenofibrate를 신규처방 받은 환자를 대상으로 각각의 약물이 지단백에 미치는 영향을 36주간 추적하여 비교분석 하였다. 결과: Acipimox를 투여 받은 환자 41명, fenofibrate를 투여 받은 환자 62명이 모집되었으며, 각각의 약물을 복용한 환자군의 기본적인 인구학적인 특성은 유의하게 상이하지 않았다. 3개월 간의 약물투여 후 두 약물군 환자 모두에서 총콜레스테롤(p < 0.05) 및 저밀도지단백(p < 0.001)이 약물투여 전과 비교하였을 때 유의하게 감소하였고, 고밀도지단백은 모든 환자에서 유의하게 증가하였다(p < 0.05). 한편 중성지방 감소율은 acipimox군이 fenofibrate군에서보다 더 크게 나타났다(p < 0.05). 약물유해반응의 빈도는 두 약물군 간에 유의한 차이가 없었다. 결론: 총콜레스테롤, 저밀도지단백 콜레스테롤 등을 감소시키거나 고밀도지단백 콜레스테롤을 증가시키는 효과는 acipimox와 fenofibrate가 유의하게 다르지 않았으며, 중성지방을 감소시키는 효과는 acipimox가 fenofibrate보다 우월하였다.

Effects of Using Convergence Circuit Weight Training on the Blood Lipids and Oxygen-carrying Factors in Middle-aged Women (융복합을 활용한 서킷 웨이트 트레이닝이 중년여성의 혈중지질 및 산소운반기능에 미치는 영향)

  • Back, Soon-Gi
    • Journal of the Korea Convergence Society
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    • v.7 no.6
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    • pp.267-274
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    • 2016
  • This study is planned to investigate the change in blood limpid and oxygen-carrying factors of middle-aged women through 12 weeks of circuit weight training. The participants worked out three times a week for 50 minutes each, with 50-80% of 1RM intensity. As such, the purpose of the study and the procedure brought about the following conclusions. First, the query results of blood limpid showed that the total amount of cholesterol, triglycerides in the blood, and low-density lipoprotein cholesterol decreased significantly, and the amount of high density lipoprotein cholesterol did not show an increase. Second, the results of oxygen-carrying factors showed that the number of oxygen-carrying red blood cells, hemoglobin, and hematocrit showed an increase. Therefore, this circuit weight training program which used weights of the geological landscape is considered as an effective way to exercise, since it had a positive impact on the oxygen-carrying capacity and cardiovascular disease prevention