• Korean Journal of Pharmacognosy
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• v.49 no.4
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• pp.362-371
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• 2018

Hwanggeumjackyak-tang (HJT) composed of Scatellaria baicalensis Georgi, Paeonia Lactiflora and Glycyrrhizae uralensis Fischer is a traditional Korean herbal medicine widely used for acute enteritis. In order to develop the tablet formulation of HJT, evaluation of the flow properties, thickness, diameter, hardness, friability and disintegration was carried out on four HJT granules according to mixed content of seven additives. Simultaneous analysis used HPLC method was performed of HJT tablet and was determined of the seven marker components; Albiflorin, Paeoniflorin, Liquiritin, Baicalin, Baicalein, Glycyrrhizic acid and Wogonin. The biological activities were examined the effect of HJT on anti-oxidation and pro-inflammation mediated by LPS-stimulation. We confirmed that both of HJT-Decoction (HJT-D) and HJT-Formulation (HJT-F) have the similar contents on total polyphenol and flavonoid and inhibited the secretion of nitro oxide (NO), interleukin $(IL)-1{\beta}$,interleukin (IL)-6, tumor necrosis factor $(TNF)-{\alpha}$ and the expression of nitric oxide synthase (iNOS), $IL-1{\beta}$, IL-6, $TNF-{\alpha}$. Therefore, the developed formulation for tablet of HJT would provide chemically and biologically the same effect compared with decoction of HJT.

• Journal of Biomedical Engineering Research
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• v.43 no.6
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• pp.382-389
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• 2022

In this study, the accuracy of the orthognathic surgical guides with single-stage split path was upgraded to realize orthognathic surgical guides with two-stage split path and simulated surgery was performed to verify its accuracy. As a result, the average error distance between the simulation model and the scan model was + 0.289 / - 0.468 mm (standard deviation 0.128), which was confirmed to be within ± 0.5 mm, which is a clinically acceptable level. Also, there was no significant difference compared with the average value of + 0.313 / - 0.456 mm (average standard deviation 0.106) of the conventional single-stage split path type device. It is judged that the use of this device can contribute to the reduction of surgical time and increase in accuracy since a separate finishing operation for bone preparation is unnecessary.

• The Korean Publising Journal, Monthly
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• s.143
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• pp.15-15
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• 1994

아산재단과 집문당이 손잡고 펴내고 있는 '아산재단연구총서'가 벌써 열한권째 나와 있다. 이 연구총서는 관계전문가가 동구권이나 구소련지역을 직접 답사하고, 현지의 자료를 충분히 활용했다는 점에서 다른 연구서와 질적 차이를 느끼게 한다.

• The Science & Technology
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• v.10 no.8 s.99
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• pp.25-27
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• 1977

한국과학재단(KOSEF)과 미국립과학재단(N.S.F)은 첫시범공동연구 프로그램으로 생물 화학공학(Bio chemical Engineering)분야에 대한 합동자문쎄미나를 8월 16일부터 19일까지 6개 세부분야의 양측전문가 20여명이 참석한 가운데 KIST 국제회의실에서 개최되었다.

• The Science & Technology
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• v.35 no.5 s.396
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• pp.10-12
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• 2002

1977년 5월 창립된 한국과학재단은 그동안 기금 1조7백85억원을 조성하여 연구비 1조1천2백14억원을 지원하였고 4천여명의 고급 과학인력을 양성하여 연구활동을 할 수 있도록 지원했다. 본지는 김정덕 이사장과의 특별대담을 통해 재단의 발자취와 앞으로의 계획을 알아보았다.

• Proceedings of the Korean Radioactive Waste Society Conference
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• 2016.05a
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• pp.403-404
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• 2016

• 대학교육
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• s.83
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• pp.135-137
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• 1996

1987년 민주화 바람을 타고 등장했던 대학 총장 직선제가 시행 9년 만에 상당한 진통을 겪고 있다. 최근 일부 사립대 재단을 중심으로 총장 직선제 폐지 움직임이 구체화되면서 재단과 교수협의회 등의 갈등이 심화되고 있다. 1996년 6월 현재 전국 26개 국.공립대학(교육.개방대 제외) 중 25개 대학이 총장 직선제를 실시하고 있고, 117개 사립대학 중 교수 직선 대학은 36개대(30.8%), 재단 선임 대학이 74개대(63.2%), 기타 대학이 7개대(6%)이다. 총장 직선제를 실시하고 있는 사립대학 36개교 중에서도 총장 직선제 폐지를 확정한 대학은 9개교, 폐지 검토중인 대학은 8개교, 폐지 여부를 재단에 일임한 대학은 1개 대학이고 나머지 18개 대학만이 폐지 계획이 없는 것으로 나타났다. 한때 약 60개의 사립대학이 총장 직선제를 실시하였으나, 1995년부터 그 숫자가 현저히 줄어든 것은 재단의 부당한 간섭으로부터 대학의 자치권을 지키는 제도적 장치로서의 총장 직선제가 대학사회의 분열을 조장하는 등 부작용을 가져오기 때문이라는 지적이 있다. 그러나 많은 국.공립대학에서 총장 직선제가 자리를 잡아가고 있고, 아직도 불건전한 사학 재단이 존재하는 한, 총장 직선제는 꼭 유지되어야 한다는 주장도 만만치 않다. 이번 호 지상토론에서는 총장 직선제에 대한 찬.반의 의견을 들어보고자 하며, 아래에 1987년부터 최근까지의 총장 직선제 관련 사건의 일지를 국내 일간지 기사를 중심으로 하여 싣는다.

• Journal of Korean Society of Steel Construction
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• v.22 no.1
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• pp.33-42
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• 2010

Patterning with a geodesic line is essential for economical or efficient usage of membrane materialsin fabric tension membrane structural engineering and analysis. The numerical algorithm to determine the geodesic line for membrane structures is generally classified into two. The first algorithm finds a non-linear shape using a fictitious geodesic element with an initial pre-stress, and the other algorithm is the geodesic line cutting or searching algorithm for arbitrarily curved 3D surface shapes. These two algorithms are still being used only for the three-node plane stress membrane element, and not for the four-node element. The lack of a numerical algorithm for geodesic lines with four-node membrane elements is the main reason for the infrequent use of the four-node membrane element in membrane structural engineering and design. In this paper, a modified numerical algorithm is proposed for the generation of a geodesic line that can be applied to three- or four-node elements at the same time. The explicit non-linear static Dynamic Relaxation Method (DRM) was applied to the non-linear geodesic shape-finding analysis by introducing the fictitiously tensioned 'strings' along the desired seams with the three- or four-node membrane element. The proposed algorithm was used for the numerical example for the non-linear geodesic shape-finding and patterning analysis to demonstrate the accuracy and efficiency, and thus, the potential, of the algorithm. The proposed geodesic shape-finding algorithm may improve the applicability of the four-node membrane element for membrane structural engineering and design analysis simultaneously in terms of the shape-finding analysis, the stress analysis, and the patterning analysis.

• Korean Journal of Medicinal Crop Science
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• v.27 no.2
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• pp.136-142
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• 2019

Background: Agrimonia pilosa Ledeb has been used as a traditional medicine for the treatment of hematuresis and uterine bleeding in Korea. It has been reported to have anti-obesity, anti-diabetes and anti-inflammaotry effect by regulating the inflammatory signaling pathway. However, the preventive effect of Agrimonia pilosa Ledeb on gastritis has not been elucidated. Thus, in the present study, we evaluated the effects of the water extract of Agrimonia pilosa Ledeb (APW) using HCl/EtOH-induced gastritis rat models. Method and Results: Gastritis was induced in rats by HCl/EtOH administration. The rats in each group were orally administered with two doses of APW (100 and 500 mg/kg). Omeprazole was used as a positive control drug. An enzyme-linked immunosorbent assay (ELISA) was used to measure the prostaglandin $E_2$ ($PGE_2$) levels in stomach. The treatment with 500 mg/kg APW reduced the gastric ulcer area. The APW treatment prevented a decreased in $PGE_2$ concentration induced by HCl/EtOH in rats. In the micronucleus test, the ratio of micronucleated polychromatic erythrocytes to polychromatic erythrocytes showed no significant change in the APW-treated group compared with the control group. Conclusions: These results indicate that APW could be used to prevent the gastritis caused by the HCl/EtOH-induced damage to stomach lining. In addition, the APW treatment showed no significant change in results of the micronucleus test. However, further experiments are required to determine how APW influenced the secretion of mucus and gastric acid using the chromosome aberration test and bacterial reverse mutation assay.

• Journal of Korean Library and Information Science Society
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• v.40 no.2
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• pp.287-310
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• 2009

This paper strives to shed a new light on current academic resource sharing initiatives of both Korea Research Foundation(KRF) and Korea Science and Engineering Foundation(KOSEF), and seeks the measure to administer information resource effectively for a unified organization, which will launch soon, through the comparison and scrutiny, and analyses of strength and weakness on current projects. It first of all attempts to draw outcomes and suggestions on the basis of issues and implications identified through the exhaustive as-is analyses in the aspects of management, service, and infrastructure of academic resource sharing initiatives carried out by each foundations. The unification of projects and information systems are discussed in two aspects, as viewed each significant measures, that is, 1) an organizational aspect in terms to develop a new academic and research information service through the unification of operation systems related to information service project of each foundation; 2) An Initiative toward the integrated service via the unification of scattered individual unit systems in each foundation.