• Title/Summary/Keyword: 장기강도

Search Result 708, Processing Time 0.034 seconds

Distribution of Mast cells and Nerves in the Developing Postnatal Submandibular and Sublingual Glands of Rats (생후 발생중인 흰쥐의 턱밑샘 및 혀밑샘에서의 비만세포와 신경의 분포양상)

  • Kim, Jae-Gon;An, Soo-Hyeon;Lee, Young-Su;Baik, Byeong-Ju;Cho, Eui-Sic
    • Journal of the korean academy of Pediatric Dentistry
    • /
    • v.26 no.2
    • /
    • pp.350-364
    • /
    • 1999
  • The distribution of mast cells and nerves were investigated in the submandibular and sublingual glands of postnatal rats, using morphometric, histochemical and immunohistochemical techniques. Mast cells were observed in the submandibular and sublingual glands of postnatal development. Number of mast cells gradually increased in both glands following development. At birth, mast cells were relatively fewer in submandibular gland than those in sublingual gland, and they were mainly distributed in parenchymal tissues. At $2{\sim}4$ weeks, most of the mast cells were observed in the connective tissues, surrounding neurovascular elements, but some mast cells were closely related with the acini of submandibular gland. PGP 9.5 immunoreactive nerve fibers were found in the submandibular and sublingual glands of all developmental age. The nerve fibers were showed in varicose shape, and mainly located in adjacent area of ducts and vascular components of both glands. The number of nerve fibers were increased rapidly until 8 weeks, but they were not increased any more until 24 weeks. Therefore, it is suggested that mast cells and nerve fibers related with each other, and that their interactions may play roles not only in maturation of secretory units but also growth and differentiation of the tubular structures of the rat submandibular and sublingual glands during postnatal development.

  • PDF

Limb Salvage Operation with Recycled Autogenous Bone Graft (자가골 재이식술을 이용한 사지 구제술)

  • Rhee, Seung-Koo;Kang, Yong-Koo;Suh, Yoo-Joon;Yoo, Jong-Min;Jung, In-Ho
    • The Journal of the Korean bone and joint tumor society
    • /
    • v.10 no.2
    • /
    • pp.96-106
    • /
    • 2004
  • Purpose: To determine the usefulness of limb salvage operation with recycled autogenous bone graft in musculoskeletal malignant tumors. Materials and Methods: Twenty nine cases, who underwent limb salvage operation with recycled autogenous bone graft for the treatment of musculoskeletal malignant tumor between February 1990 and January 2003, were included. There were 18 males and 11 females and the mean age was 33 years (range, 10 to 65 years). The mean follow-up period was 51.8 months (range, 18 to 117 months). The Enneking stage was IIA in 10 cases and IIB in 19 cases. The recycling method of autogenous bone was deep freezing in 6 cases, autoclaving in 11 cases, pasteurization in 7 cases and the composite of autoclaving and vascularized fibular graft in 5 cases. The union of junctional site was evaluated radiologically and the functional results was analyzed by the grading systems of the International Symposium On Limb Salvages (ISOLS). Results: The mean union time was 7.2 months (range, 3 to 15 months). The union took 5.8 months (range, 4 to 8 months) in deep freezing, 9.7 months (range, 6 to 15 months) in autoclaving, 5.9 months (range, 4 to 8 months) in pasteurization, and 5 months (range, 4 to 8 months) in the composite of autoclaving and vascularized fibular graft. The mean functional evaluation percentage was 76.8% (range, 40 to 90%). It was 65.8% (range, 40 to 85%) in deep freezing, 76.6% (range, 40 to 90%) in autoclaving, 81.6% (range, 70 to 90%) in pasteurization, and 83.4% (range, 75 to 90%) in the composite of autoclaving and vascularized fibular graft. There were 6 cases of complications including 1 case of local recurrence, lung metastasis, infection, fracture, respectively and 2 cases of nonunion. Conclusion: The limb salvage operation with recycled autogenous bone graft is a useful treatment method for the musculoskeletal malignant tumors. Particularly, autoclaving is the most reliable sterilization method. The vascularized fibular graft can compensate decreased osteoinductivity and mechanical strength of recycled bone. So, the composite of autoclaving and vascularized bone graft seems to be a favorable treatment method for high grade malignant musculoskeletal tumors.

  • PDF

Effects of Tree Density Control on Carbon Dynamics in Young Pinus densiflora stands (소나무 유령림의 임목밀도 조절이 탄소 동태에 미치는 영향)

  • Song, Su-Jin;Jang, Kyoung-Soo;Hwang, In-Chae;An, Ki-Wan;Lee, Kye-Han
    • Journal of Korean Society of Forest Science
    • /
    • v.105 no.3
    • /
    • pp.275-283
    • /
    • 2016
  • The objective of this study was to examine carbon dynamics with biomass, soil $CO_2$ efflux, litter and root decomposition after tree density control in young Pinus densiflora stands. The stands were established with 50% thinning, clear-cut, and control stands with three pseudo-replicated plots and a bare soil plot in 8-year-old Pinus densiflora nursery field. Monthly measurements were conducted from March 2012 to February 2014 and aboveground biomass and coarse-roots were estimated by derived allometric equations. Average diameter growth at root collar in control and thinned was 0.89 cm and 1.48 cm per year, respectively, and the diameter growth of control stand was significantly higher than that of thinned stands (p<0.05). Total biomass was estimated to 5.17, $4.85kg\;C\;m^{-2}$ per year in control and thinned, respectively. Annual soil $CO_2$ efflux in control, thinned, clear cut, and bare soil was 3.71, 3.90, 4.17, $4.56kg\;CO_2\;m^{-2}\;yr^{-1}$, respectively and removing trees significantly increased soil $CO_2$ efflux (p<0.05). Net Ecosystem Production (NEP) was 1.57, 1.36, -0.67, $-1.25kg\;C\;m^{-2}\;yr^{-1}$ in control, thinned, clear cut and bare soil in the young Pinus densiflora stands. NEP was significantly decreased by removing trees. Thinning increased diameter at root collar and carbon of individual tree and recovered 86% of carbon removed by thinning after one-year. In addition, soil $CO_2$ efflux increased and NEP increased by thinning. Results of this study, tree density control such as thinning increased the carbon storage and growth of the young Pinus densiflora stands.

Studies on the Durability of Mortars (모르타르의 내구성에 관한 연구)

  • 고재군
    • Magazine of the Korean Society of Agricultural Engineers
    • /
    • v.11 no.4
    • /
    • pp.1798-1802
    • /
    • 1969
  • The experiment was carried out as one of the basic studies to improve the alkali-resistance of cement mortars and it was conducted to investigate some propetties of mortars relating to weight losses when exposed to 0.1 N salution of sodium hydroxide. The experiment and the results obtained are summarized as follow; 1. The specimens used in this experiment were made of 5 centi-meter cubes of mortar having such various ratios of mix by weight as 1 : 1, 1 : 3, 1 : 5, 1 : 7 and 1 : 10. 2. Physical tests included compressive strengths at 7 days, 28 days, 3 months, and 6 month, and 5 hour boiling absorption test. 3. In alkali test, every specimen was immersed into 0.1 N solutions of sodium hydroxide. The specimens exposed to the alkali solution were weighed to determine the weight losses of the alkail-corroded at one week interval for 7 week's exposure and the old alkali solutions were also changed to fresh solutions when weighed the weight losses by alkali attack at one week interval. 4. According to the alkail test after 7 week's exposure, no weight losses were observed on ratios of mix 1:1 and 1:3 and slight weight losses occurred on ratios of mix 1:5 and 1:7, but relatively large amount of weight losses were showed by 36.6 per-cent on ratios of mix 1:10. It was also found that the weight losses of the alkali-corroded were extremely lower than those of the acid-corroded at the some concentrations as 0.1 N of solutions. 5. In order to make better quality of alkali-resistant mortar it might recomend that a 1:7 mix or richemixes, use of small amount of mixing water for watertight, 20 per cent or less absorption by 5 hour boiling 1,600 kirogram per cubic meters or denser densities by absolute dry base are available for physical properties of mortar. It could conclude acid-resistant mortars were so high alkali-resistant, that it is expected to make and improve the acid-resistant mortars for getting rid of damages by alkali attack.

  • PDF

An Analysis of Model Bias Tendency in Forecast for the Interaction between Mid-latitude Trough and Movement Speed of Typhoon Sanba (중위도 기압골과 태풍 산바의 이동속도와의 상호작용에 대한 예측에서 모델 바이어스 경향분석)

  • Choi, Ki-Seon;Wongsaming, Prapaporn;Park, Sangwook;Cha, Yu-Mi;Lee, Woojeong;Oh, Imyong;Lee, Jae-Shin;Jeong, Sang-Boo;Kim, Dong-Jin;Chang, Ki-Ho;Kim, Jiyoung;Yoon, Wang-Sun;Lee, Jong-Ho
    • Journal of the Korean earth science society
    • /
    • v.34 no.4
    • /
    • pp.303-312
    • /
    • 2013
  • Typhoon Sanba was selected for describing the Korea Meteorological Administration (KMA) Global Data Assimilation Prediction System (GDAPS) model bias tendency in forecast for the interaction between mid-latitude trough and movement speed of typhoon. We used the KMA GDAPS analyses and forecasts initiated 00 UTC 15 September 2012 from the historical typhoon record using Typhoon Analysis and Prediction System (TAPS) and Combined Meteorological Information System-3 (COMIS-3). Sea level pressure fields illustrated a development of the low level mid-latitude cyclogenesis in relation to Jet Maximum at 500 hPa. The study found that after Sanba entered the mid-latitude domain, its movement speed was forecast to be accelerated. Typically, Snaba interacted with mid-latitude westerlies at the front of mid-latitude trough. This event occurred when the Sanba was nearing recurvature at 00 and 06 UTC 17 September. The KMA GDAPS sea level pressure forecasts provided the low level mid-latitude cyclone that was weaker than what it actually analyzed in field. As a result, the mid-latitude circulations affecting on Sanba's movement speed was slower than what the KMA GDAPS actually analyzed in field. It was found that these circulations occurred due to the weak mid-tropospheric jet maximum at the 500 hPa. In conclusion, the KMA GDAPS forecast tends to slow a bias of slow movement speed when Sanba interacted with the mid-latitude trough.

Biodistribution of Iodine-131-Iodomisonidazole and Imaging of Tumor Hypoxia in Mice bearing CT-26 Adenocarcinoma (CT-26 선암을 접종한 마우스에서 Iodine-131-Iodomisonidazole의 생체분포 및 종양저산소증의 영상화)

  • Kim, Hye-Won;Kim, Chang-Guhn;Yoon, Kwon-Ha;Kim, Hyun-Jeong;Juhng Seon-Kwan;Roh, Byung-Suk;Yang, David J.;Kim, E.Edmund;Lee, Hyun-Chul
    • The Korean Journal of Nuclear Medicine
    • /
    • v.33 no.3
    • /
    • pp.289-297
    • /
    • 1999
  • Purpose: Misonidazole is a radiosensitizer that binds in hypoxic cells. The purpose of this study was to find out the feasibility of I-131-Iodomisonidazole (IMISO) for imaging of tumor hypoxia. Materials and Methods: Tosyl precursor was dissolved in acetonitrile and I-131-NaI was added to synthesize IMISO. Balb/c mice inoculated with CT-26 adenocarcinoma were injected with IMISO. Mice were sacrificed at 1, 2, 4, 24 hr and % of injected dose per gram of tissue (%ID/g) was determined. For scintigraphy and MRI, mouse bearing CT-26 adenocarcinoma was administered with IMISO and imaging was performed 4 hr after. Then, mouse body was fixed and microtomized slice was placed on radiographic film for autoradiography Results: %ID/g of tumor was 1.64 (1h), 0.98 (2h), 0.85 (4h) and 0.20 (24h), respectively. At 24h, %ID/g of tumor was higher than that of all other tissues except thyroid. Tumor to muscle ratio increased with time and tumor to blood ratio also increased with time and reached 1.53 at 24 hr. On autoradiogram, tumor was well visualized as an increased activity in central hypoxic area of the tumor which corresponds to the area of high signal intensity on T2-weighted MR image. On scintigraphy, tumor uptake was visualized. Conclusion: This results suggest that IMISO may have a potential for tumor hypoxia imaging in mouse model. However, further study is needed to improve it's localization in tumor tissue and to achieve acceptable images of tumor hypoxia.

  • PDF

Shallow subsurface structure of the Vulcano-Lipari volcanic complex, Italy, constrained by helicopter-borne aeromagnetic surveys (고해상도 항공자력탐사를 이용한 Italia Vulcano-Lipari 화산 복합체의 천부 지하 구조)

  • Okuma, Shigeo;Nakatsuka, Tadashi;Komazawa, Masao;Sugihara, Mitsuhiko;Nakano, Shun;Furukawa, Ryuta;Supper, Robert
    • Geophysics and Geophysical Exploration
    • /
    • v.9 no.1
    • /
    • pp.129-138
    • /
    • 2006
  • Helicopter-borne aeromagnetic surveys at two different times separated by three years were conducted to better understand the shallow subsurface structure of the Vulcano and Lipari volcanic complex, Aeolian Islands, southern Italy, and also to monitor the volcanic activity of the area. As there was no meaningful difference between the two magnetic datasets to imply an apparent change of the volcanic activity, the datasets were merged to produce an aeromagnetic map with wider coverage than was given by a single dataset. Apparent magnetisation intensity mapping was applied to terrain-corrected magnetic anomalies, and showed local magnetisation highs in and around Fossa Cone, suggesting heterogeneity of the cone. Magnetic modelling was conducted for three of those magnetisation highs. Each model implied the presence of concealed volcanic products overlain by pyroclastic rocks from the Fossa crater. The model for the Fossa crater area suggests a buried trachytic lava flow on the southern edge of the present crater. The magnetic model at Forgia Vecchia suggests that phreatic cones can be interpreted as resulting from a concealed eruptive centre, with thick latitic lavas that fill up Fossa Caldera. However, the distribution of lavas seems to be limited to a smaller area than was expected from drilling results. This can be explained partly by alteration of the lavas by intense hydrothermal activity, as seen at geothermal areas close to Porto Levante. The magnetic model at the north-eastern Fossa Cone implies that thick lavas accumulated as another eruption centre in the early stage of the activity of Fossa. Recent geoelectric surveys showed high-resistivity zones in the areas of the last two magnetic models.

An Analysis of Teachers' Level of Usage and Concern Over the 7th Science Curriculum (제7차 과학 교육과정에 대한 지구과학 교사들의 관심도와 활용도 분석)

  • Lee, Yong-Seob;An, Hyun-Hee;Kim, Sang-Dal;Kim, Jong-Hee
    • Journal of the Korean earth science society
    • /
    • v.24 no.5
    • /
    • pp.378-392
    • /
    • 2003
  • The purpose of this study is to investigate the depth of earth science teachers' concern over the 7th Science Curriculum and levels of their use of it in reality, using the tools "Concern" and "Levels of use" which are two important tools use in CBAM. The results of the study are as follows. How much concern do the earth science teachers have over the 7th Science Curriculum? There are seven stages (from 0 stage to 6 stage) of teachers' concern over the curriculum. o stage represents teachers' indifference to the curriculum and 98% teachers are placed in this stage. According to the study on teachers' teaching experience, teachers having from 10 to 14 years of teaching experience are the most indifferent to the 7th Science Curriculum, compared to other teachers. Which levels of use of the 7th science curriculum do earth science teachers choose in reality? There are five levels of use (from 1 to 5) of the 7th curriculum. 43.97% of teachers are placed in the 3rd level called "Mechanical level", which represents a teacher-concerned learning method with consideration of learners' response. According to the study on teachers' frequency of level of use in the fields of "Instruction objects, Instruction contents, Instruction methods, Instruction materials and Evaluation.", teachers chose high levels of use in the fields of "Instruction objects and Instruction contents" and low levels of use in the other three fields. What factors are barriers for earth science teachers to perform the 7th Science Curriculum in reality? 80.9% of teachers have trouble performing the 7th Science Curriculum in reality because of too much routine work, official papers, and lack of instructional materials, laboratories, training systems and workshops. The two biggest barriers among the above are routine work and of official papers. According to the study on teachers' teaching experience, teachers having from 0 to years of teaching experience have the most trouble in performing the curriculum in reality, compared to other teachers.

Characteristics of Kawasaki Disease Patients who are Unresponsive to High-dose Intravenous Immunoglobulin Therapy (가와사끼병에서 정맥용 면역글로불린 불응군의 특성)

  • Kook, Dong-Hyuk;Ko, Yong-Min;Lee, Keun-Young;Kim, Dong-Un;Lee, Kyung-Yil;Lee, Joon-Sung
    • Pediatric Infection and Vaccine
    • /
    • v.15 no.2
    • /
    • pp.180-187
    • /
    • 2008
  • Purpose : We wanted to determine the characteristics of patients with Kawasaki disease (KD) who were unresponsive to intravenous immunoglobulin (IVIG). Methods : The patients with KD were divided into two groups: the IVIG responsive group (25 cases) and the IVIG unresponsive group (14 cases). We analyzed various parameters before and after the administration of IVIG, including the complete blood cell count with the differential count (%), the erythrocyte segmentation rate (ESR), the C-reactive protein (CRP) level and the protein and lipid profiles. Results : The IVIG unresponsive group had a prolonged duration of fever and a higher incidence of CAL compared to the IVIG responsive group (P<0.001, respectively). Before IVIG infusion, the neutrophil differential, the ESR and the CRP values were higher (P<0.001), and the total protein and albumin values were lower in the IVIG unresponsive group (P=0.01) compared to the IVIG responsive group. After IVIG infusion, there were no significant changes in the WBC count and CRP levels in the IVIG unresponsive group. The reduction of the HDL-cholesterol levels by IVIG was more significant in the unresponsive group (P=0.02). Conclusion : A more severe and prolonged inflammatory response occurred in the IVIG unresponsive group at an early stage, and this finding can be detected by such inflammatory parameters as the neutrophil count and the CRP and HDL-cholesterol levels after IVIG infusion.

  • PDF

Effects of Feeding Induced Molting on the Performance, Egg Quality, and Visceral Organs in Laying Hens (산란계에서 급이환우가 산란계의 생산성과 계란의 품질 및 주요 장기에 미치는 영향)

  • Hong, E.C.;Na, J.C.;You, D.C.;Jang, B.G.;Kim, H.K.;Choi, Y.H.;Park, H.D.;HwangBo, J.
    • Korean Journal of Poultry Science
    • /
    • v.34 no.3
    • /
    • pp.197-205
    • /
    • 2007
  • This study was conducted to compare the effect of feeding molting and fasting molting on the performance, egg quality, and visceral organs in laying hens for animal welfare. Eighty one 62-wk-old White Leghorn hens that egg production was over 80% and average weight was $1.6{\pm}0.3\;kg$ were used in this study. Treatments were control (non-molt treatment), feeding molt treatment, and fasting molt treatment. The three treatments were administered to three replicate group of nine hens wherein each group. All treatment groups were fed the basal diet (CP 15%, ME 2,700 kal/kg) for two weeks as the adaptation period. Induced molt diets contains low CP (6.7%) and low energy (2,200 kal/kg). Test periods were 14 days for feeding molting and 10 days for fasting molting. Egg production decreased to be 0% at 10 days of feeding molting treatment, but at 2 or 3 days of fasting molting treatment. Egg production restarted after 19 days ending molt at feeding molting treatment, while after 24 days at fasting molting treatment. On the egg quality was improved at molting treatments (p<0.05) except egg yolk. Egg shell tissue was crowded at molting treatment to compare to control. Liver weights, heart weight, and oviduct weight of laying hens decreased at molting treatments (p<0.05). Finally, feeding molting might could be replaced fasting molting on the welfare and further studies were needed about molting program.