• Radiation Oncology Journal
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• v.4 no.2
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• pp.115-128
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• 1986

Hyperthermia can enhance the radiation effect as a synergistic reaction in combined X-ray irradiation and hyperthermia; hyperthermia sensitize radioresistant S-phase cells and inhibit cellular recovery from sublethal damage. We fabricated 100 watts, 2450 MHz microwave applicator for hyperthermia and planned the method and condition of heating and measured the temperature by using Agar phantom as a preliminary test. For biological examination, 102 rats were divided into 4 groups as hyperthermia, X-ray irradiation (6Gy-15Gy), combined X-ray and hyperthermia, and normal control groups. Microscopic examination of the rectum and bladder was done and the results were as followings: 1. The microwave generator with 100 watts, 2450MHz magnetron could be heating up to $40^{\circ}{\sim}50^{\circ}C$ for one hour in living tissue. 2. The thermal distribution in tissue equivalent phantom with microwave can be maintained at $40^{\circ}{\sim}44^{\circ}C$ in area of 3cm in depth and 2-10cm in diameter. 3. In Hyperthermia alone group, there was submucosal edema of the rectum but no histologic change in the urinary bladder was seen. 4. The minimal necrosis of the mucosa was appeared in the rectum and bladder after 15 days of 6 Gy and 8 Gy irradiation respectively. The minimal necrosis of the muscle layer of rectum and bladder was appeared after 15 days of 8Gy and 60days of 10Gy irradiation respectively. 5. In combined group of radiation and hyperthermia, thermal enhancement ratio (calculated at necrosis of mucosa and muscle layer) of rectum and bladder was 1.0, and it suggest that there is no change of tolerance dose of normal rectum and bladder.

• Journal of the Korean Society of Food Science and Nutrition
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• v.36 no.12
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• pp.1523-1528
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• 2007

The feeding effects of mugwort (Artemisia vulgaris L.) extracts (ME) on the anti-oxidative actions of ICR mouse skin was investigated. To study the antioxidative effects of ME on ICR mouse skin, female ICR mice were grouped into basic diet group (control), ascorbic acid diet group (AA-2.5, AA-5.0, AA-10.0 and AA-20.0 mg/kg BW/day) as a positive control and experimental diet group (mugwort extract; ME-25, ME-50, ME-100, and ME-200 mg/kg BW/day) and fed for 10 weeks. Protein contents in ME-50, ME-100, and ME-200 feeding group were increased ($3.1%{\sim}11.1%$) and hydroxyl radical contents were significantly decreased ($10.4%{\sim}17.4%$) compared to control group. Oxidative stress signals and oxidized protein contents were significantly reduced to the range of 15.3 to 17.1% in ME-100 and ME-200 groups. Also, superoxide dismutase (SOD) activity was significantly increased to the range of 15.0% to 23.3% in ME-100 and ME-200 groups. Catalase activities were significantly increased ($14.0%{\sim}36.9%$) in all groups in a dose-dependent pattern. Antioxidative ability of ME showed similarity to that of ascorbic acid.

• Korean Journal of Health Psychology
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• v.16 no.3
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• pp.537-555
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• 2011

The purpose of this study was two-fold. First, comparisons on the psychological and physical attributes of normal weight, overweight, and obese children were conducted. Second, the influence of BMI and physical fitness interaction on psychological adaptation in children with obesity was explored. Participants were 245 children between the ages of 9 and 13 years (64.5% males). Data on children considered overweight (n = 45) or obese (n = 78) were gathered from the Korean Obese Children's Physical Activity (KOCPA) projects. Normal weight children (n = 122) were recruited from two Seoul elementary schools. Psychological measurements included Weight Efficacy Life-style Questionnaire (WEL), Physical Self-efficacy Scale (PSES), Child Dietary Self-efficacy Scale (CDSS), Self-concept Inventory (SCI), and the Korean version of the Pediatric Quality of Life Intervention TM Version 4.0 Generic Core Scales (PedsQLTM4.0). BMI (kg/m2) and physical fitness (e.g., aerobic endurance, flexibility) were recorded by experts in exercise physiology. Results showed that children in the high BMI group reported poorer psychological adaption and demonstrated lower physical fitness when compared to the remaining groups. Compared to normal weight children, children considered overweight and obese were found to have lower physical self-efficacy, more negative self-concept, and poorer quality of life. Further, these children also had significantly lower physical fitness levels than their normal weight counterparts. Physical fitness was found to have a significant main effect on weight efficacy (WEL), physical self-efficacy (PSES), and quality of life (PedsQL) in children considered overweight or obese. A significant BMI-physical fitness interaction effect was found for self-concept (SCI) only. Children with higher BMI reported poorer self-concept regardless of fitness level whereas children with lower BMI and higher fitness reported more positive self-concept. Implications and limitations are discussed.

• Journal of the Korean GEO-environmental Society
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• v.11 no.1
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• pp.19-26
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• 2010

The batch experiments and response surface methodology (RSM) have been applied to the investigation of the cadmium (Cd) adsorption by coal fly ash (CFA). CFA having maximum Cd removal mass of 8.51 mg/g were calculated from Langmuir model. Cd removal reaction with different initial pH ranged from 4 to 9. When the initial pH was higher, Cd was removed more by adsorption and precipitation. These results suggest that the lower pH cause an increase of $H^+$ ion concentration which competed with Cd ions for exchange sites in CFA. Also, The Cd adsorption was mathematically described as a function of parameters initial Cd concentration ($X_1$), initial pH ($X_2$), and initial CFA mass ($X_3$) being modeled by use of the Box-Behnken methods. Empirical models were developed to describe relationship between the experimental variables and response. Statistical analysis indicates that tree factors ($X_1$, $X_2$, and $X_3$) on the linear term (main effects), and tree factors ($X_1X_2$, $X_1X_3$, and $X_2X_3$) on the non-linear term (Interaction effect; cross-product) had significant effects, respectively. In this case, the value of the adjusted determination coefficient (adjusted $R^2=0.9280$) was closed to 1, showing a high significance of the model. Statistical results showed the order of Cd removal at experimental factors to be initial initial pH > initial Cd concentration > initial CFA mass.

• Journal of Life Science
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• v.14 no.4
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• pp.676-682
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• 2004

Nutritional concentrations by chemical analyses of mushroom fermented milk were protein 2.87%, fat 0.09%, carbohydrates 6.0%, dietary fiber 0.3%, lactose 2.01%, sucrose 1.23%, calcium 95.9 mg/100 g and iron 0.08 mg/100 g. The present study was undertaken to investigate the hypoglycemic effects of the equal volume of either water (streptozotocin (STZ)rontrol rats), mushrooms water-extract (STZ-extrart fed rats), mushroom fermented milk product (STZ-mushroom yogurt fed rats) or mushroom fermented milk supernatant (STZ-supernatant fed rats) (10%, v/w), in STZ-induced diabetic rats for 3 week period. The mushroom fermented milk given to the STZ-diabetic rats decreased the blood glucose significantly and increased the blood insulin, compared with the STZ-control rats. The supernatant and mushroom water extract also slightly retarded the development of hyperglycemia in the STZ-diabetic rats. Taken together the results, the mushroom yogurt may have a potential for the hypoglycemic effect in the STZ-diabetic rats.

• Journal of the Korea institute for structural maintenance and inspection
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• v.22 no.2
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• pp.161-168
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• 2018

This study is the analytical review on the inelastic region of CRC column strength curve. The inelastic region of CRC column strength curve is based on the Bleich theory and the maximum residual stress of $0.5{\sigma}_y$. This is somewhat conservative by considering the fact that the maximum residual stress of $0.3{\sigma}_y$ is well known. This study proposes column strength curve for nonlinear behavior of hot rolled structural steel members under axial force and tangent modulus Et, with the maximum residual stress of $0.3{\sigma}_y$ and compares them with those of CRC. The stress of the inelastic column under axial compression exceeds proportional limits and reaches yielding point before applied load render the column bent. The column strength curve that depends on gradually yielding state of section needs to be reviewed. In this study, it is derived that the critical load formular according to material yielding with the maximum residual stress of $0.5{\sigma}_y$ and compared with CRC column design curve.

• Economic and Environmental Geology
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• v.44 no.5
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• pp.387-397
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• 2011

In this study, we conducted the study of the merits and demerits of the laser flash and the divided-bar methods for measuring the thermal conductivity of rocks and investigated applicability of the divided-bar apparatus which was developed by KIGAM. The laser flash method can measure thermal diffusivity, specific heat capacity, and thermal conductivity of rocks with even small thickness (< ~3 mm) in the high temperature range($25-200^{\circ}C$) in non-contact mode. For the laser flash method, samples must be uniform and homogeneous. In the case of the divided-bar method, the apparatus measures only thermal conductivity of rock samples at the room temperature. We measured thermal conductivities of 12 rock samples with low density and high porosity using two methods. In the laser flash method, there exist potential errors caused by the effect of pulse dispersion and reflection by various minerals and porosity in rock samples; the difference in thermal conductivity values measured on the front surface and the opposite surface ranges from 0.001 to 0.140 W/mK with the standard deviation of 0.003~0.089 W/mK, which seems to be caused by heterogeneity of rock samples. On the contrary, the divided-bar apparatus shows stable thermal conductivity measurements and relatively small measurement errors; the difference in thermal conductivity values, just as we applied to the laser frash method, is 0.001~0.016 W/mK with the standard deviation 0.001~0.034 W/mK. In turn, the divided-bar method can be applied to more thick samples that are more representative of bulk thermal conductivity.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.37 no.4
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• pp.320-328
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• 1992

The soybean yield forcasting models based on climatic elements in six locations were estimated by the STEPWISE/MAXR, Cp statistics and GLM procedure of SAS. The climatic elements were aerial temperature, sunshine hours and precipitation from May to October in 20 years. The investigated six locations were Chunchon, Suwon, Cheongju, Kwangju, Iri and Jinju. The important climatic elements for main effects in Chunchon model were August sunshine hours-linear term, August precipitation-quadratic. June temperature to August precipitation and May temperature to August precipitation were interaction terms. The quadratic August precipitation was assumed to be related to yield in Chunchon. The main effects of Suwon were linear-June temperature, quadratic June sunshine hours and June precipitation. These terms affected yields negatively. The main effects of Cheongju were linear June temperature and quadratic August precipitation. May temperature to June precipitation, July to August precipitations were interactions. The main effects of Kwangju were linear July precipitation, quadratic June temperature and July precipitation. June to July sunshine hours of interaction terms influenced yield negatively. The main effects of Iri were linear May sunshine hours, quadratic May and July sunshine hours. May temperature to May precipitation and June to July precipitations affected yields negatively. The main effects of Jinju were linear June and August precipitations. August temperature to August sunshine hours, June sunshine hours to July precipitation and June to August precipitation were interactions. In linear terms, June and August precipitations and, in interactions, August to August sunshine hours were negative efficacies respectively. The included year variables in Chunchon, Suwon, Kwangju, and Jinju model building were recognized as a linear trend based on an assumption that the technological factors have improved through times.

• Journal of Life Science
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• v.17 no.5 s.85
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• pp.634-640
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• 2007

Our previous study suggested that n-3 fatty acid deficiency was associated with significantly reduced spatial learning as assessed by Morris water maze test. Here we investigated an effect of n-3 fatty acid deficiency on rat brain, retina and serum fatty acyl compositions at 15 wks age using a first generational artificial rearing technique. Newborn Rat pups were separated on day 2 and assigned to two artificial rearing groups or a dam-reared control group. Pups were hand fed artificial milk via custom-designed nursing bottles containing either 0.02%(n-3 Deficient) or 3.1% (n-3 Adequate) of total fatty acids as a-linolenic acid(LNA). At day 21, rats were weaned to either n-3 deficient or n-3 adequate pelleted diets and fatty acid compositions of brain, retina and liver were analyzed at 15 wks age. Brain docosahexaenoic acid(DHA) was lower(58% and 61%, P<0.05) in n-3 deficient in comparison to n-3 adequate and dam-reared groups, receptively, while brain docosapentaenoic acid(DPAn-6) was increased in the n-3 deficient group. In retina and serum fatty acid compositions, the decreased precentage of DHA and increased precentage of DPAn-6 were observed. These results suggested that artificial rearing method can be used to produce n-3 fatty acid deficiency in the first generation and that adequate brain DHA levels are required for optimal brain function.

• Food Science and Preservation
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• v.13 no.3
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• pp.363-368
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• 2006

This study was performed to develop flavor materials from Elsholtzia ciliata Hylander with analyzing functionality and aroma profile and to optimize supercritical fluid extraction method and optimum condition. The qualities of water extracts such as total yield total phenolic compound electron donation ability, estragole and L-carvone, were affected by extraction pressure than time. The response variables had significant with pressure than with time and the established polynomial model was suitable(P>0.05) model by Lack-of-Fit analysis. The optimum extraction conditions which were limited of maximum value for dependent variables under experimental conditions based on central composite design were 238 bar and 42 min.