• YAKHAK HOEJI
• /
• v.28 no.1
• /
• pp.35-48
• /
• 1984

우리나라 사람들에게는 유달리 높은 간염 발병률이 나타나고 있고 더우기 바이러스성 간염의 경우 풍토병 내지 전염병이라고 할 정도의 양상을 띠고 있다. 현재까지는 이러한 간질환에 적절한 치료약이 없는 점을 감안하여 저자들은 생약으로 부터 간질환에 유효한 성분을 분리하여 치료약으로 사용할 수 있도록 하기위하여 집중적인 연구를 지난 5년간 계속하여 왔다. 연구의 내용은 동서양의 고전및 연구보문을 조사하여 간보호 및 치료학으로 사용한 생약에 관한 문헌적 조사, 이들 생약중 채집 및 구입이 가능한 식물을 구하여 생약엑기스 제조, 이들 엑기스를 간염 동물 모델의 하나인 $CCl_{4}$로 유발시킨 간독성에 대한 보호작용의 검색, 보호작용을 나타내는 생약중에서 자원적 측면을 고려하여 국내에서 많이 생산되는 차전자(Plantago asiatica seeds)를 선택하였고, 차전자로 부터 간보호 작용을 나타내는 유효성분으로 iridoid 계열물질인 aucubin을 분리하였다. 그러나 aucubin이 차전자에 소량 밖에 없으므로 aucubin이 다량 함유된 식나무(Aucuba japonica)로 aucubin 추출자료생약을 바꾼후 aucubin의 간보호 작용을 간염 동물모델인, $CCl_{4}$ D-galactosamine 및 $\alpha$-amanitin등으로 유발시킨 간독성에 대한 보호작용을 보여 주었기 때문에, 이러한 간보호작용의 기전을 규명하는 연구를 진행하였고, 다음은 aucubin 자체의 급성 독성 및 기타 독성 유발여부를 밝히는 연구 등으로 요약 될 수 있다.

• Proceedings of the Korea Information Processing Society Conference
• /
• 2021.05a
• /
• pp.564-566
• /
• 2021

최근 가상 휴먼은 국방, 의료, 교육, 엔터테인먼트 등 다양한 분야에서 널리 활용되고 있다. 가상 휴먼을 이용한 상호작용은 사용자가 현실 세계의 실제 친구와 대화하는 것처럼 자연스럽게 소통하는 방식으로 운용이 되고, 이를 위해서는 사용자의 음성, 동작, 감정 등 다양한 입력을 기반으로 반응하는 가상 휴먼 출력 등 상호작용 매핑 관계를 제작하여야 한다. 하지만, 기존 가상 휴먼 상호작용 방법은 미리 정해진 패턴을 수작업인 프로그래밍을 통해 제작하여 개발 기간이 오래 걸리고, 수정이 용이하지 못한 단점이 있다. 본 논문에서는 가상 휴먼 상호작용을 위해 음성, 동작, 감정 등 사용자의 멀티모달 입력과 가상 휴먼 반응에 대한 저작을 수행하는 툴킷을 제시한다. 본 논문에서 제시한 저작도구를 통해 쉽고 빠르게 사용자와 가상 휴먼 상호작용 표현을 생성할 수 있다.

• Journal of KIISE:Software and Applications
• /
• v.26 no.8
• /
• pp.1018-1027
• /
• 1999

속성 문법은 언어의 정적인 의미구조를 표현하는 형식적인 표기법으로 동적인 의미구조를 표현하기는 부적절하다. 동적 의미구조를 잘 명세하고 명세된 언어를 구현하기 위해서 기존의 속성 문법을 확장하여 언어 구현에 필요한 동적인 작용들(actions)을 잘 표현해야 한다. 본 논문에서는 속성 문법을 확장하여 정적이고 동적인 의미구조를 잘 표현할 수 있는 새로운 작용 식(action equation)을 제시한다. 제시된 작용 식(action equation)의 동적인 의미 구조로 부터 SIMP 언어의 점진 해석기(incremental interpreter)를 설계하고 구현한다. 점진 해석기는 언어 기반의 프로그래밍 환경에서 수정된 부분만을 번역하여 프로그램의 전체 실행 결과를 얻는 해석기를 의미한다. 본 해석기는 SUN 1000에서 Lex와 Yacc을 사용해서 C 언어로 설계하고 구현하였다. 예제 프로그램을 실행시켰을 때 배정 문이나 IF문의 경우는 매우 효율적이었고 Loop의 경우는 재실행될 필요가 있는 영향받는 명령문들이 적을수록 점진 해석이 더 효율적으로 수행된다.Abstract Attribute grammars are a formal notation which expresses the static semantics of programming languages, but they are not suitable for expressing dynamic semantics. To describe dynamic semantics and implement a specified language, we extend attribute grammars and present new action equations which describe static and dynamic semantics. The incremental interpreter of a SIMP language is designed and implemented from the dynamic semantics of presented action equations. The incremental interpreter is to translate only modified part in the language-based programming environments and have results of whole program.Our interpreter is implemented in C with Lex and Yacc on SUN 1000. When we execute example programs, the incremental evaluation of any assignment and IF statements executes efficiently. But in the case of loop, we execute efficiently when the effected statements to be reexecuted in the loop are of small number.

• Journal of Korean Society of Coastal and Ocean Engineers
• /
• v.23 no.1
• /
• pp.63-69
• /
• 2011

In this paper, the wave forces on a cylindrical aquaculture fish cage, which consists of the porous mesh with the uniform porosity, are analyzed using matched eigenfunction expansion method. The boundary condition on the porous net is derived based on the Darcy's law, which implies that the velocity of the fluid passing through the net is linearly proportional to the pressure difference between two sides of the net. The wave forces and wave responses are investigated by changing the porous parameter of porous net as well as the submerged position (floating type, bottom-mounted type) of an aquaculture fish cage. It is found that the wave forces on a bottom-mounted type are largely decreased compared with that on a floating type. Also, the porosity of the netting structure plays an important role in reducing the wave forces and the wave elevation in the vicinity of an aquaculture fish cage.

• Geotechnical Engineering
• /
• v.12 no.5
• /
• pp.27-40
• /
• 1996

Box culvert has long since been used for various purposes , water and sewerage works, communication and electricity facilities, subway, railway, etc. In urban area, the construetion of box culvert generally consists of excavation-installation of the culvert-backfill. However, the existing design methods for earth pressure on the box culvert do not take into account the excavation(or backfill) geometry. ' A new method considering excavation geometry for earth pressure on box culvert is suggested here. The lateral earth pressures by the newly suggested method agree relatively with results of finite element analyses, but those of existing method are greatly overestimated. The vertical pressure on the top of the box culvert by the new method is similar to those of existing method and finite element analysis. However, the reactional pressure on the bottom of the box culvert depends largely upon the stiffness of the foundation soil. The reactional pressure by the new method agrees well with that of finite element analysis, only when the stiffness is low. From the finite element analysis it is shown that the lateral earth pressure on box culvert depends upon the excavated slope (G) and the net bottom distance (Bc).

• Journal of Korean Society of Coastal and Ocean Engineers
• /
• v.21 no.3
• /
• pp.216-223
• /
• 2009

A transverse drag interaction coefficient of the equivalent resistance coefficient formula for square multi-piers higher than water depth and arranged with equal intervals was studied. From the assumption that the energy loss due to drag interaction according to transverse intervals of resistance bodies is essentially identical to the energy loss due to thick orifice according to porosities, the transverse drag interaction coefficient was derived by employing the orifice's energy loss coefficient. The equivalent resistance coefficient formula including the drag interaction coefficient was compared with the numerical experiments using FLOW-3D, the performance of which was verified by Kim et al.(2008) in the experimental condition with the multi-piers. The comparisons showed good agreement and thus, the equivalent resistance coefficient formula, which does not only consider frictional resistance but also consider the multi-piers' drag resistance varied according to the intervals in longitudinal or transverse direction, was verified.

• Journal of the Korean Geotechnical Society
• /
• v.23 no.11
• /
• pp.5-14
• /
• 2007

In this study, Matsuda formula used to evaluate the loads acting on the pillar was investigated and load reduction factor(${\alpha}$) was evaluated by numerical analysis to better apply for the design. From the results, normal stress was concentrated to one side due to excavation of preceding tunnel after construction of pillar. And 86.5% of maximum normal stress was revealed partly unequally when the ground was poor. By numerical analysis, $14{\sim}83%$ of total loads calculated by Matsuda formula decreased and then, from these results, load reduction factor(${\alpha}$) was estimated. From now on, stability and economic aspects could be guaranteed by applying the load reduction factor(${\alpha}$).

• Journal of the Korea institute for structural maintenance and inspection
• /
• v.27 no.6
• /
• pp.144-151
• /
• 2023

In this study, a database was established by collecting experimental results on various concrete mixtures subjected to freeze-thaw cycles, based on which an artificial neural network-based prediction model was developed to estimate durability resistance of concrete. A regression analysis was also conducted to derive an equation for estimating relative dynamic modulus of elasticity subjected to freeze-thaw loads. The error rate and coefficient of determination of the proposed artificial neural network model were approximately 11% and 0.72, respectively, and the regression equation also provided very similar accuracy. Thus, it is considered that the proposed artificial neural network model and regression equation can be used for estimating relative dynamic modulus of elasticity for various concrete mixtures subjected to freeze-thaw loads.

• Journal of Korean Society of Steel Construction
• /
• v.13 no.2
• /
• pp.201-210
• /
• 2001

A numerical analysis and experimental study were performed to investigate the behavior and strength of tube-gusset connection subjected to axial and lateral forces. To investigate the behavior of the connections, experiment was conducted by applying three directional loads. Local buckling and local plastic bending deformation of the connection were observed from the test. Analytical results were compared with test results for the limited cases. Primary interests here are the effect of eccentricity on the strength of the connection. To suggest a formula for the strength of tube-gusset connection, lateral forces were replaced with equivalent wall moment and eccenrtric vertical component force of lateral force. Ultimate strength formula for the each force was proposed. Finally, nondimensionalized ultimate strength interaction relationships between the wall moment of tube($M_w$), vertical axial force($P_v$), and eccentric vertical component of lateral force($P_e$) were formulated through parametric study.

• The Science & Technology
• /
• s.471
• /
• pp.102-103
• /
• 2008