• Title/Summary/Keyword: 자연변이

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유전자 알고리즘의 우수형질 선택기법에 관한 연구

  • 김태식;정성용
    • Journal of Korea Society of Industrial Information Systems
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    • v.2 no.1
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    • pp.143-157
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    • 1997
  • 유전자 알고리즘(Genetic Algorithms)은 자연의 법칙에서 그 아이디어를 찾은 것으로 순회 방문자 문제(Traveling Salesman Problem : TSP) , 분배문제, 라우팅문제 등과 같은 전형적인 Combinatorial Optimization 문제에 적용되고 있다. 한편 이러한 유전자 알고리즘의 성능을 향상시키기 위해 알고리즘 실행과정에 적용할 수많은 이론과 경험적인 기법이 제시되고 있는데 이러한 기법들은 대부분 우수형질을 확보함으로써 최적의 값을 효과적으로 탐색하기 위한 것이다. 즉, 개체의 우수 형질 확보를 위한 부모 선택방법, 교차의 범위와 위치 및 방법, 그리고 돌연변이의 크기와 방법등이 포함된다. 본 연구에서는 자연의 법칙에서와 같이 자손 세대의 형질이 부모 세대보다 우수할 수 있음을 전제로 적응도 가중치에 의한 확률적인 방법에 의해서 선택하는 방법을 개선하여 부모세대가 같지 않게 하고, 우수형질이 유전되도록 하여 자손세대의 적응도가 부모세대보다 높도록 함으로써 최적의 값을 효과적으로 탐색할 수 있음을 실험하였다.

보류 및 탈수성 분석을 위한 새로운 수초지기(II)

  • 김향수;윤혜정;류정용;김용환;신종호;송봉근
    • Proceedings of the Korea Technical Association of the Pulp and Paper Industry Conference
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    • 2000.11a
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    • pp.115-115
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    • 2000
  • 제지 공정의 효율적인 운영을 위해 공정변수를 확인하는 작업은 매우 중요하다. 탈수 특성 평가를 위하여 SR(Shopper- RegIer)과 CSF(Canadian Standard Freeness tester) 그리고 원형 수초지기 동의 비난류 상태의 자연탈수 특성 평가 장치와 동적 조건의 감압식 탈수성 분석기 퉁이 도입되어 있으나 제지 공정에 보다 더 근접한 탈수, 보류 특성을 평가 하기 위하여 특히 wet-end 첨가제들의 효능을 보다 정확히 분석할 수 있도록 난휴 발생과 감압 탈수 둥을 유도한 탈수 특성 평가 장치 개발의 필요성이 커지고 있다Il, 2) 이미 소개된 RDA-HSF

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Analysis of Leaf Morphological Variation of 11 Natural Populations of Acer pictum subsp. mono (Maxim.) Ohashi (고로쇠나무 11개 자연집단의 잎의 형질 변이 분석)

  • Song, Jeong-Ho;Hur, Seong-Doo
    • Korean Journal of Plant Resources
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    • v.24 no.5
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    • pp.540-548
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    • 2011
  • Characteristics of leaf morphology was examined in 11 natural populations of Acer pictum subsp. mono (Maxim.) Ohashi in Korea. Nested Anova showed that there were statistically significant differences among populations as well as among individuals within populations in all 14 quantitative characters. In all the leaf characters, variance components among individuals within populations were higher than those among populations. Some morphological characters such as the ration of Blade length to Petiole length (0.90), Uower lobe width (0.85), Blade length (0.83), and Middle lobe width (0.83) showed the relative high differences in the values of differentiation (Dij) among populations. Of the ten populations, Gwangyang (1.36) and Cheongyang (1.30) were highly differentiated based on the total mean Dij of fourteen morphological characters, while Ulju (0.30) and Jeongseon (0.44) were scarcely differentiated.

Lack of p53 Gene Nucleotide Change in Mutation Hot Spots During HeLa Cell Apoptosis by Adriamycin (아드리아마이신에 의한 HeLa 세포의 자살 과정 중 p53 유전자의 돌연변이 빈발 부위에서의 핵산 변화의 부재)

  • Ryu, Seung-Wook;Kim, Jung-Woo;Kim, Eun-Hee
    • The Journal of Natural Sciences
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    • v.9 no.1
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    • pp.31-37
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    • 1997
  • Apoptosis is an important event in the anticancer drug therapy. p53 was demonstrated to serve a key component to lead tumor cell death by inducing apoptosis. However, recent study showed the presence of p53 independent apoptotic pathway (Gaftenhaus et al., 1996). We were curious to know it apoptosis induced by adriamycin, a genotoxic anticancer agent, involved p53 gene mutation. Thus this study investigated the p53 gene mutation status among HeLa cell population during apoptosis induced by adriamycin. Under our experimental condition, 12 hour treatment of 1 ${\mu}m$ adriamycin caused apoptosis which was monitored by DNA fragmentation assay. In order to see the p53 gene mutation status, exons of 5, 7 and 8 of p53 gene, where previously reported p53 mutation hot spots reside, were amplified by PCR and nucleotide sequence change was scanned. However, no nucleotide change was observed among apoptotic HeLa cell population. Therefore this study demonstrated that adriamycin induced apoptosis without causing p53 gene damage.

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Modifying Effects of Ellagic Acid in Food on Carcinogenesis (식품 중 Ellagic acid의 발암수식효과)

  • 장동덕;신동환;홍충만;조재천;한정희
    • Journal of Food Hygiene and Safety
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    • v.13 no.1
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    • pp.29-33
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    • 1998
  • The effect of ellagic acid (EA) on hepatocarcinogenesis induced by diethylnitrosamine (DEN), and promoted by phenobarbital (PB), and hepatectomized partially was investigated in male Wi star rats. All rats were injected 200 mg of DEN intraperitoneally, received 0.05 % of PB in drinking water at week 2, and hepatectomized 2/3 of liver at week 3. Rats of group 2, 3 and 4 were fed diet containing 400ppm EA for 1 week before DEN administration, for 9 weeks from beginning of experiment to sacrifice and for 6 weeks from PB treatment to sacrifice respectively. Rats of group 5, 6 and 7 were fed 800 ppm EA in the same manner as group 2, 3 and 4. Animals were killed at 8 weeks after DEN administration. The number and area of preneoplastic lesions were quantified the glutathione-S-transferase placental-form (GST-P) positive foci using immunohistochemical method. Decrease of number and area of the positive foci was observed in the rats fed 400 ppm EA for 9 weeks. In addition, the reduction of the foci can examine in all group fed 800 ppm EA. In conclusion, EA inhibited the hepatocarcinogenesis induced by DEN when it was administrated 800 ppm.

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Chromosome Redundancy and Tree Phenotype Variation in Autotetraploid Trifoliate Orange (동질 사배체 탱자에서 염색체 배가와 수체 표현형의 변이)

  • Oh, Eun Ui;Chae, Chi-Won;Kim, Sat-Byul;Lu, Jian Liang;Yun, Su-Hyun;Koh, Sang-Wook;Song, Kwan Jeong
    • Horticultural Science & Technology
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    • v.32 no.3
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    • pp.366-374
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    • 2014
  • The study was conducted to investigate the possibility that epigenetic DNA methylation causes tree phenotypic variation in autotetraploids through evaluating the phenotypic variation and DNA methylation in autotetraploids occurred spontaneously from diploid trifoliate orange. Chromosome analysis confirmed that fourteen trifoliate orange trees of selected by flow cytometry were tetraploids (2n = 4X = 36) without any aneuploids. Chromomycin A3 staining determined that these trees were all autotetraploid with doubled chromosome set. Tree phenotypes, such as tree height and width, branching number, length, and angle, internode length, and leaf characteristics, varied in the autotetraploids. Chlorophyll indices were diverse in the autotetraploids, but photosynthetic rates were not significantly different. In addition, a wide range of variation was observed in stomatal density and guard cell length. Analysis of global cytosine DNA methylation showed that there was a variation of the methylation level in autotetraploids. More than half of 14 autotetraploids had at least 2 times higher methylation level than diploid trifoliate orange. The results indicate that tree phenotypic variation in autotetraploids might be related to global DNA methylation for reducing gene redundancy.

Productivity of the Rice Plants at the Abandoned Crop Field Established from the Shattered Grains by Combine Harvesting (Combine 수확시 탈락볍씨의 경련 휴경조건하 자연상태에서의 수량성)

  • 허상만;임준택
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.36 no.1
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    • pp.79-84
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    • 1991
  • The rice plants (Oryza sativa L.) established from the shattered grains by combine harvesting at the previous year showed great variations of yield and yield components from site to site at the abandoned rice crop field. The cultural condition was very similar to direct seeding under no-tillage system but no cultural practices such as application of fertilizer, weed control, irrigation and drainage had been carried out. The highest yield of 188kg/10a was observed at one of the quadrats randomly located on the field, which showed the possibility of exploitation of no-tillage system. The interrelationship between crop growth and coverage of weed species was measured by calculating the correlation coefficients. The investigations of how to establish sufficient number of seedlings per unit area, plant succession on the abandoned crop field, crop mixture with legume crops, and breeding appropriate plant type of rice for the enhancement of competitive ability would be required for the success of no-tillage system.

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자음의 단어내 음운환경별로 본 음가변화

  • 김종미
    • The Journal of the Acoustical Society of Korea
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    • v.13 no.5
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    • pp.69-76
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    • 1994
  • Acoustic cues of some consonantal phonology were tested in Korean words. All Korean consonants were recorded and acoustically analyzed in controlled phonological environments :ⅰ) word-initial, ⅱ) inter-vocalic, and ⅲ) word-final positions. The observed acoustic regulations are : ⅰ) The lengths of obstruents are longer word-initially than word-finally, ⅱ) The lengths of sonorants are longer word-finally than in word-initial or inter-vocalic positions, ⅲ) The formants of the lateral sound /l/ are higher word-finally than intervocalically. The phonological explanations of these acoustic regulations can be found in the rules of ⅰ) inter-vocalic voicing of plain stops, ⅱ) syllable-final unreleasing of obstruents, ⅲ) word-initial aspiration of stops, and ⅳ) liquid alternation between [r] and [l]. Numerical data of all these acoustic regulations are reported in order to facilitate their application toward improving naturalness for speech synthesis and accurateness for speech recognition.

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Pre-service Teachers' Understanding of Randomness (예비교사들의 무작위성 개념 이해 조사)

  • Ko, Eun-Sung;Lee, Kyeong-Hwa
    • School Mathematics
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    • v.12 no.4
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    • pp.455-471
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    • 2010
  • Understanding of randomness is essential for learning and teaching of probability and statistics. Understanding of randomness prompts to understand natural and social phenomena from the point of view of mathematics, and plays a role of base in understanding of judgments based on rational interpretation on these phenomena. This study examined whether pre-service teachers recognize this, and they understand randomness included in various contexts. According to results, they did not have a understanding of randomness in the context related to measuring, while they grasped randomness in simple and joint events. This implies that they lack the understanding of variability which is essential in the context of measuring. This study, therefore, suggests that the settings of measuring should be introduced into probability and statistics education, especially that data from measuring should be analyzed focusing on the variability in the data set.

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Decrease in Genetic Variation of Overwintering Populations of the Diamondback Moth during Seasonal Occurrence (배추좀나방의 계절적 발생과 월동집단의 유전적 분화 감소)

  • Kim, Eunseong;Park, Areum;Park, Youngjin;Kim, Jooil;Kim, Yonggyun
    • Korean journal of applied entomology
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    • v.54 no.4
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    • pp.303-310
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    • 2015
  • The diamondback moth, Plutella xylostella, overwinters in some protected areas in Korea. Using a sex pheromone trap, the adults were monitored since the occurrence of the overwintering populations. In Andong, P. xylostella exhibited four adult peaks in a year. Biological characters, such as cold tolerance, insecticide susceptibility, and developmental rate, were analyzed and showed a significant variation among different local overwintering populations. Population genetic variation was assessed with molecular markers, in which the initial high genetic variation among the overwintering populations decreased with the progress of seasons. These results suggests that there may be a significant migration of P. xylostella to decrease the genetic variation among the different local populations that are different in biological characters.