• The Korean Journal of Nuclear Medicine Technology
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• v.15 no.2
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• pp.26-29
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• 2011

Purpose: The general test method of the Korean Pharmacopeia specifies the test method on the clauses of quality control after manufacturing. According to KFDA Guidance for Medicines, standards of residual solvents regulates the maximum permissible dose of acetonitrile as 400 ppm, ethanol as 5,000 ppm, and acetic acid as 5,000 ppm. This study aims at identifying the type of resiual solvents in the final [F-18]FDG vial of an automatic synthesizer and measure its residual quantity. Materials and Methods: The center carried out residual solvents test of [F-18]FDG injection using Agilent Technologies 7890A with a Flame Ionization Detector. The column of Agilent Technologies 7890A used in measuring of residual solvents was CP WAX column ($30m{\times}0.53mm{\times}1.0{\mu}m$) and analysis condition was split mode 1:1 at the initial temperature $70^{\circ}C$ which was increased $20^{\circ}C/minute$ after two minutes and maintained at the final $140^{\circ}C$ for two minutes. The analysis method was as following: Firstly, ethanol-acetonitrile-acetic acid mixture was classified into four types of concentration (250-25-250 ppm, 1,000-100-1,000 ppm, 3,000-300-3,000 ppm, and 6,000-600-6,000 ppm), and $1.0{\mu}L$ of each type of concentration was injected into gas chromatography followed by an analysis of its peak domain. Then, a calibration-curve by the external standard method was drawn based on the analysis result. Results: While ethanol and acetonitrile were detected in TRACERlab MX, FASTlab had additional acetic acid. The residual quantity of the ethanol-acetonitrile-acetic acid mixture evaluated using the calibration-curve was average 72 ppm ethanol, 54 ppm acetonitrile, and 1030 ppm acetic acid for FASTlab, whereas average 439 ppm ethanol and 79 ppm acetonitrile for TRACERlab MX. This indicated that both of them were within the maximum permissible dose. Conclusion: Solvent residues in the [F-18]FDG injection were all within maximum permissible doses and proper to be used to examine a patient. The result indicated that types and quantities of solvent resides of radioactive pharmaceuticals vary depending on the automatic synthesizer.

• Journal of Food Hygiene and Safety
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• v.22 no.3
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• pp.173-178
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• 2007

Children may respond differently to the caffeine from adults because they have different physiologic makeup and are functionally immature in terms of hepatic and renal function; this leads to the slower clearance of caffeine in early life. Therefore, children are often assumed to be more susceptible to caffeine effects. Alarge number of food supplements may interfere with these processes, and therefore caffeine exposure may have more serious consequences for children than for adults, irrespective of sensitivity. However, there has never been a national dietary survey on caffeine intakes in children. The purpose of our study was to identify caffeine intakes and beverage sources of caffeine in a representative sample of children in Busan, Korea. Caffeine intakes were based only on beverages included in the Continuing Surveys of Food Intakes by individuals. The caffeine content of the beverages ranged from 2.8 to 65.2mg/100ml for cola, soft drinks, and teas. Caffeine was not completely absent from caffeine-free colas, juice, and milk. In this study, cola-type beverages were an important dietary source of caffeine in the children. Daily caffeine intake for children was estimated to range from 12.5 to 250 mg/day. In general, the acceptable daily intake (ADI) of caffeine should cover the entire population including children. Therefore, special considerations should be needed regarding the consumption of soft drinks containing caffeine to children below the 12 years of age.

• Food Science and Preservation
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• v.14 no.1
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• pp.35-41
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• 2007

As the consumption of environmentally friendly agricultural products increases, food safety is at the forefront of public health concerns. We analyzed the biological hazards of 26 species of leaf vegetables and 4 species of fruit according to types of cultivation (conventional or organic filming) and distribution system (giant retailers or organic food stores) using various culture media, automatic bacterial identification systems, and microscopy, Total bacterial count of unwashed agricultural product ranged from $5.2{\times}10^{3}\;to\;1.5{\times}10^{5}\;CFU/mL$ (from 0.1 g of agricultural products), and the average count dropped 25-fold (range, 8-60-fold) after water washing. Microbial levels of washed organic agricultural products were $6.0{\times}10^{2}-1.9{\times}10^{4}\;CFU/mL$, and were not significantly different f개m the microbial loads on conventionally farmed produce. There was no significant difference in bacterial count from agricultural produce purchased from giant retailers or organic food stores. Total microbial count of Chinese cabbage, welsh onion, red chicory and kale were comparatively high, and Enterobacter cloacae was isolated most frequently. Parasites were detected in agricultural products purchased from conventional farm products in the stores of giant retailers, and in organic food stores, and parasite prevalence was especially high in Chinese cabbages and welsh onion. The study indicated that cultivation methods and distribution systems did not cause significant differences in biological contamination levels of agricultural produce. Some vegetables and fruits were highly contaminated effective sanitizing methods to reduce these biological hazards are needed.

• Journal of the Korean Society of Food Science and Nutrition
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• v.42 no.3
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• pp.464-477
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• 2013

There is a great need to develop a training program proven to change behavior and improve knowledge. The purpose of this study was to evaluate employee hygiene knowledge, hygiene practice, and cleanliness, before and after HACCP system implementation at one small-size restaurant. The efficiency of the system was analyzed using time-temperature control after implementation of u-HACCP$^{(R)}$. The employee hygiene knowledge and practices showed a significant improvement (p<0.05) after HACCP system implementation. In non-heating processes, such as seasoned lettuce, controlling the sanitation of the cooking facility and the chlorination of raw ingredients were identified as the significant CCP. Sanitizing was an important CCP because total bacteria were reduced 2~4 log CFU/g after implementation of HACCP. In bean sprouts, microbial levels decreased from 4.20 logCFU/g to 3.26 logCFU/g. There were significant correlations between hygiene knowledge, practice, and microbiological contamination. First, personnel hygiene had a significant correlation with 'total food hygiene knowledge' scores (p<0.05). Second, total food hygiene practice scores had a significant correlation (p<0.05) with improved microbiological qualities of lettuce salad. Third, concerning the assessment of microbiological quality after 1 month, there were significant (p<0.05) improvements in times of heating, and the washing and division process. On the other hand, after 2 months, microbiological was maintained, although only two categories (division process and kitchen floor) were improved. This study also investigated time-temperature control by using ubiquitous sensor networks (USN) consisting of an ubi reader (CCP thermometer), an ubi manager (tablet PC), and application software (HACCP monitoring system). The result of the temperature control before and after USN showed better thermal management (accuracy, efficiency, consistency of time control). Based on the results, strict time-temperature control could be an effective method to prevent foodborne illness.

• Journal of the Korean Society of Radiology
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• v.10 no.2
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• pp.81-87
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• 2016

In this study we proposed a texture feature analysis algorithm that distinguishes between a normal image and a diseased image using CT images of some fatty liver patients, and generates both Eigen images and test images which can be applied to the proposed computer aided diagnosis system in order to perform a quantitative analysis for 6 parameters. And through the analysis, we derived and evaluated the recognition rate of CT images of fatty liver. As the results of examining over 30 example CT images of fatty liver, the recognition rates representing a specific texture feature-value are as follows: some appeared to be as high as 100% including Average Gray Level, Entropy 96.67%, Skewness 93.33%, and Smoothness while others showed a little low disease recognition rate: 83.33% for Uniformity 86.67% and for Average Contrast 80%. Consequently, based on this research result, if a software that enables a computer aided diagnosis system for medical images is developed, it will lead to the availability for the automatic detection of a diseased spot in CT images of fatty liver and quantitative analysis. And they can be used as computer aided diagnosis data, resulting in the increased accuracy and the shortened time in the stage of final reading.

• Journal of Digital Convergence
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• v.14 no.5
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• pp.317-323
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• 2016

This paper suggests a system that can detect malfunctions of the temperature testing equipment, and then notify this information to surroundings using arduino. Precision electronics need a test under extremely high/low temperature using temperature called a chamber. If this chamber have a malfunction situation, the precision electronics under test is damaged and scrapped. Especially when the temperature test is automatically conducted at night with no representative, this system monitors the actual temperature of the tested product in real-time by attaching a temperature sensor to the inside of the test equipment. In case when it is out of the temperature range set up by the tester, the damage to high-priced products can be prevented in the condition of extremely high/low temperature, by turning off the power of the temperature testing equipment, and also notifying this information to the worker at night-time. Regardless of the equipment manufacturers, proposed system in this paper can be applied to all kind of temperature testing equipments, and it can be also produced for low cost.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.15 no.11
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• pp.2321-2326
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• 2011

Cervical vertebrae are a complex structure and an important part of human body connecting the head and the trunk. In this paper, we propose a method to extract sternocleidomastoid muscle from ultrasonography images of cervical vertabrae automatically. In our method, Region of Interests(ROI) is extracted first from an ultrasonography image after removing unnecessary auxiliary information such as metrics. Then we apply Ends-in search stretching algorithm in order to enhance the contrast of brightness. Average binarization is then applied to those pixels which its brightness is sufficiently large. The noise part is removed by image processing algorithms. After extracting fascia encloses sternocleidomastoid muscle, target muscle object is extracted using the location information of fascia according to the number of objects in the fascia. When only one object is to be extracted, we search downward first to extract the target muscle area and then search from right to left to extract the area and merge them. If there are two target objects, we extract first from the upper-bound of higher object to the lower-bound of lower object and then remove the fascia of the target object area. Smearing technique is used to restore possible loss of the fat area in the process. The thickness of sternocleidomastoid muscle is then calculated as the maximum thickness of those extracted objects. In this experiment with 30 real world ultrasonography images, the proposed method verified its efficacy and accuracy by health professionals.

• Proceedings of the ESK Conference
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• 1998.04a
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• pp.81-86
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• 1998

제품의 사용성 평가에 주로 이용되고 있는 방법의 하나인 비디오 프로토콜 분석(Video Protocol)은 정 보의 질과 양적 측면에서 다른 방법에 비하여 우위에 있다고볼 수 있다. 그러나 비디오 프로토콜 분석 은 많은 물적, 시간적 비용의 투자가 필요한 방법이다. 이러한 문제점들은 컴퓨터의 정보 관리 기능을 활용한다면 충분히 해결될 수 있는 것들이다. 이에 '사용자 중심 디자인을 위한 컴퓨터 지원 시스템 개발' 의 일환으로 사용자중심 디자인 프로세스의 마지막 단계인 개발된 제품의 사용성 평가에 활용될 수 있는 컴퓨터 지원시스템으로써 컴퓨터를 활용한 비디오 정보 분석방법에 관하여 연구하고자 한다. 본 연구는 사용성 평가 비디오 정보를 분석할 수 있는 컴퓨터 지원 시스템을 개발하는데 그 목적을 두고 있다. 사용자 의 기초정보를 파악하는 단계, 사용성평가에 이용되는 제품의 정보를 설정하는 단계, 사용성의 다양한 측면 정보를 비디오정보로부터 추출하는 단계, 추출된 정보와 제품정보, 사용자 기초정보를 연관지어 분석하는 단계, 그리고 마지막으로 분석된 정보로부터 디자인개선의 컨셉을 도출하는 단계 등에 컴퓨터를 활용할 수 있는 통합적인 사용성 평가 컴퓨터에서 제어가 쉽게 이루어 지도록 하고, 이를 화면에 재생시키면서 관찰자가 필요한 정보를 실시간에 분석하고 기록할 수 있는 모든 지원 도구들을 포함하여, 이러한 기록이 자동적으로 분석정보로 활용되어 다양한 측면에서 제품의 사용성평가를 이룰 수 있도록 한다. 또한 분석정보를 도표화하고 분석과 정보검출, 정보생성 단계들 간의 피드백이 원활히 이루어 질 수 있도록 하여분석의 정밀도를 높일 수 있도록 한다. 니즈 데이터베이스가 확충되면 각 사용상황하의 사용성 문제 해결안뿐만 아니라 서로 관련이 있는 사용상황간의 연계 연구를 통해 좀 더 광범위한 개념의 제품 개발도 가능해 질 수 있을 것이다.와 만족도와의 관계 및 이상형에 대해 구체적으로 파악할 필요가 있다. 또한, 신체에 대한 이상형은 시대의 여러 여건에 따라서 변화할 수 있으므로 의복 착용자가 의복을 통해서 표현하고자 하는 이상형의 시대적 변화를 살펴볼 필요가 있다. 따라서 본 연구에서는 신체에 대한 인식도 및 만족도, 이상형에 대한 설문지 조사와 신체측정을 통하여 신체 크기에대한 만족도를 객관적인 척도로 고찰하고, 이상형과 실제 체형에 관하여 고찰하고자 한다. 도한, 1992년도 자료와의 비교를 통하여 시대에 따른 신체만족도와 이상형의 변화를 파악하고자 한다. 이를 기초로 한 의복원형 제작 및 의복 디자인에 대한 연구를 통해 의복의 맞음새가 좋을뿐만 아니라 의복착용자들 에게 심리적 만족을 줄 수 있는 의복 제작에 도움이 될 수 있을 것이다.적입지로 분석되었다.등 다양한 모형들을 고려해 본 뒤, 적절한 모형을 적용할 것이다. 가로망 설계 모형에서 신호제어를 고려하기 위해서는 주어진 가로망에 대한 통행 배정과정에서 고려되는 통행시간을 링크통행시간과 교차로 지체시간을 동시에 고려해야 하는데, 이러한 문제의 해결을 위해서 최근 활발히 논의되고 있는 교차로에서의 신호제어에 대응하는 통행배정 모형을 도입하여 고려하고자 한다. 이를 위해서 지금까지 연구되어온 Global Solution Approach와 Iterative Approach를 비교, 검토한 뒤 모형에 보다 알맞은 방법을 선택한다. 차량의

• Journal of the Institute of Electronics Engineers of Korea SD
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• v.41 no.2
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• pp.27-32
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• 2004

Absolute optical angle sensor is described that is an essentially digital opto-electronic device. Its purpose is to resolve the relative and absolute angle position of coded disk using Pseudorandom-code and Geometry-code. In this technique, the angular position of disk is determined in coarse sense first by Pseudorandom-code. A further fine angular position data based on Pixel count is obtained by Geometry-code which result 0.006$^{\circ}$ resolution of the system provided that 7 ${\mu}{\textrm}{m}$ line image sensor are used. The proposed technique is novel in a number of aspects, such that it has the non-contact reflective nature, high resolution of the system, relatively simple code pattern, and inherent digital nature of the sensor. And what is more the system can be easily modified to torque sensor by applying two coded disks in a manner that observe the difference in absolute angular displacement. The digital opto-electronic nature of the proposed sensor, along with its reporting of both torque and angle, makes the system ideal for use in intelligent vehicle systems. In this communication, we propose a technique that utilizes Pseudorandom-code and Geometry-code to determine accurate angular position of coded disk. We present the experimental results to demonstrate the validity of the idea.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.40 no.11
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• pp.51-62
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• 2003

This paper presents a novel survivor memeory management and decoding techniques with sequential backward state transition control in the trace back Viterbi decoder. The Viterbi algorithm is an maximum likelihood decoding scheme to estimate the likelihood of encoder state for channel error detection and correction. This scheme is applied to a broad range of digital communication such as intersymbol interference removing and channel equalization. In order to achieve the area-efficiency VLSI chip design with high throughput in the Viterbi decoder in which recursive operation is implied, more research is required to obtain a simple systematic parallel ACS architecture and surviver memory management. As a method of solution to the problem, this paper addresses a progressive decoding algorithm with sequential backward state transition control in the trace back Viterbi decoder. Compared to the conventional trace back decoding techniques, the required total memory can be greatly reduced in the proposed method. Furthermore, the proposed method can be implemented with a simple pipelined structure with systolic array type architecture. The implementation of the peripheral logic circuit for the control of memory access is not required, and memory access bandwidth can be reduced Therefore, the proposed method has characteristics of high area-efficiency and low power consumption with high throughput. Finally, the examples of decoding results for the received data with channel noise and application result are provided to evaluate the efficiency of the proposed method.