• Title/Summary/Keyword: 자극재

Search Result 271, Processing Time 0.028 seconds

Studies on Anti-Wrinkle and Whitening Effects of Liposomes Containing Acerola Extract Mixture (아세로라 추출물 혼합 리포좀의 주름, 미백 효과에 대한 연구)

  • Kim, Su Jin;Oh, Won Jun;Kwon, Sung Pil;Nam, Gaewon
    • Journal of the Society of Cosmetic Scientists of Korea
    • /
    • v.47 no.4
    • /
    • pp.341-352
    • /
    • 2021
  • Acerola is an excellent ingredient because of its high natural vitamin C content, but it is difficult to stabilize and has hardly been studied as a cosmetic material. Therefore, this study developed a mixed liposome preparation for stabilizing acerola extract. As a safety test, the skin irritation test was evaluated by BCOP assay and HET-CAM assay. We evaluated the inhibition of tyrosinase activity, the whitening effect of melanin production, and the wrinkle effect of prochloragentype-I C-peptide production, and confirmed the possibility of functional cosmetics. In addition, a cream of liposomes containing acerola extract mixture was developed to evaluate the clinical studies of skin wrinkles and whitening. BCOP assay, HET-CAM assay and human skin primary irritation test results of liposomes containing acerola extract mixture showed no irritation and were safe from skin and eye. The result of tyrosinase activity by 75.8% at 1,000 ㎍/mL. As a result of the melanogenesis inhibition test, liposome with acerola extract showed the melanin content by 46.2% at 1,000 ㎍/mL that does not effect the viability of the B16F10 cell line. The result of collagen production test using ELISA kit, liposomes containing acerola extract mixture showed collagen synthesis ability by 152.1% at 1,000 ㎍/mL that does not affect the viability of the HS68 cell line. But it did not showed any inhibition of collagenase (MMP-1) activity at all concentrations in the MMP-1 activity inhibition test in the HS68 cell line. We performed clinical studies for the whitening and skin-wrinkle activity of cream containing acerola extract mixes liposome, was showed that the melanin contents and wrinkle was statistically significant reduction. These results suggest that liposomes containing acerola extract mixture have safe natural material, and skin wrinkle, whitening effects allowing their application in cosmetics as a natural product.

Effects of Waste Refractory Powder and Desulfurization Gypsum as Activator on the Properties of High Volume Blast Furnace Slag Mortar with Illite (자극제로서 폐내화물 및 탈황석고가 일라이트 및 고로슬래그 다량 치환 모르타르의 물성에 미치는 영향)

  • Yun, Weon-Keun;Han, Min-Cheol
    • Journal of the Korean Recycled Construction Resources Institute
    • /
    • v.5 no.2
    • /
    • pp.185-191
    • /
    • 2017
  • The objective of this paper is to investigate the effect of waste refractory powder(WRP) and desulfurization gypsum(FGD) as activators on the flow properties and the strength development of high volume blast furnace slag mortar incorporating illite(BSM) having adsorption and deodorization. To fabricate the BSMs with 60% of W/B, blast furnace slag are incorporated with 45% and 65%, respectively. WRP and FGD are substituted from 5 to 10%. Test results indicate that the flow is decreased with increase of WRP and FGD, while increase of WRP and FGD enhance the compressive strength due to accelerated reaction of blast furnace slag, The use of illite results in a decrease of compressive strength. pH has increasing tendency until 7days, while it has reduction. In this paper, optimal dosages of WRP and FGD are believed to be around 5% each.

Engineering Characteristics of Blast Furnace Slag Cement Mortar Using Chlorine Bypass System-Dust as Alkali Activator (Chlorine Bypass System-Dust를 알칼리 자극제로 사용한 고로슬래그 시멘트 모르타르의 공학적 특성)

  • Han, Min-Cheol;Lee, Dong-Joo
    • Journal of the Korean Recycled Construction Resources Institute
    • /
    • v.8 no.2
    • /
    • pp.235-244
    • /
    • 2020
  • This study conducted a series of studies to offer a novel method of using CBS-dust that produced as by-product in the manufacture of cement. Four different contents of BS and CBS-dust were adopted for test parameters of this study. Mortar with 50% of W/B was fabricated. First, in the case of the fresh mortar, the flow decreased as the CBS-dust replacement rate increased, but the binder composition ratio BS 45% and 65% showed higher fl ow than Pl ain when repl acing CBS-dust 5%. In the case of air content, overall, the tendency was proportional to the CBS-dust replacement rate, and chloride tended to exceed the reference value at all replacement rates except for the CBS-dust 0% replacement. The compressive strength of the hardened mortar shows the resul t that the strength is improved when the CBS-dust is repl aced by 5% to 10%, and the CSH gel and structure formation is confirmed by microstructure analysis through the hydration reaction when the CBS-dust is replaced. Therefore, for a given condition CBS-dust is used as a early-strength admixture in a concrete secondary product that uses a large amount of admixture without reinforcing bars it can be an effective method for enhancing the strength of concrete as an alkali activator.

Memory in visual search: Evidence from search efficiency (시각 탐색에서의 기억: 탐색 효율성에 근거한 증거)

  • Baek Jongsoo;Kim Min-Shik
    • Korean Journal of Cognitive Science
    • /
    • v.16 no.1
    • /
    • pp.1-15
    • /
    • 2005
  • Since human visual system has limited capacity for visual information processing, it should select goal-relevant information for further processing. There have been several studies that emphasized the possible involvement of memory in spatial shift of selective attention (Chun & Jiang, 1998, 1999; Klein, 1988; Klein & MacInnes, 1999). However, other studies suggested the inferiority of human visual memory in change detection(Rensink, O'Regan, & Clark, 1997; Simons & Levin, 1997) and in visual search(Hotowitz & Wolfe, 1998). The present study examined the involvement of memory in visual search; whether memory for the previously searched items guides selective attentional shift or not. We investigated how search works by comparing visual search performances in three different conditions; full exposure condition, partial exposure condition, and partial-to-full exposure condition. Revisiting searched items was allowed only in full exposure condition and not in either partial or partial-to-full exposure condition. The results showed that the efficiencies of attentional shift were nearly identical for all conditions. This finding implies that even in full exposure condition the participants scarcely re-examined the previously searched items. The results suggest that instant memory can be formed and used in visual search process. These results disagree with the earlier studies claiming thar visual search has no memory. We discussed the problems of the previous research paradigms and suggested some alternative accounts.

  • PDF

Strength Properties of Alkali-Activated Lightweight Composites with Alkali Activators of Different Types and Amounts (알칼리 자극제의 종류 및 첨가율에 따른 무시멘트 경량 경화체의 강도특성)

  • Lee, Sang-Soo;Kim, Yun-Mi;Park, Sun-Gyu
    • Journal of the Korea Institute of Building Construction
    • /
    • v.14 no.4
    • /
    • pp.301-307
    • /
    • 2014
  • In order to reduce the emission of carbon dioxide($CO_2$), this research use blast furnace slag in concrete manufacture, as 100% replacement of cement. The aim of this study is to investigate the density and strength properties of alkali-activated lightweight composites with alkali activators of different types and different amounts. The bubble for achieving the lightweight of alkali-activated lightweight composites was generated in the reaction between the paper ash and the alkali activators instead of using a foaming agent. Lightweight formed concrete was conducted basic experimental for determining replacement ratio of paper ash. Then, the density and strength were measured according to the types and the contents of the alkali accelerator that can react with the paper ash. As results, the optimum replacement ratio of the paper ash was 5%. The alkali activator containing NaOH 12.5% obtained the lowest weight of $1.13g/cm^3$. Also, compressive strength were relatively high. Therefore, this study demonstrated that alkali accelerator with a certain amount of NaOH can achieve relatively high strength and lightweight alkali-activated lightweight composites.

Hydration Reaction of Non-Sintering Cement Using Inorganic Industrial Waste as Activator (무기계 산업폐기물을 자극제로 이용한 비소성 시멘트의 수화반응)

  • Mun, Kyoung-Ju;Lee, Chol-Woong;So, Seung-Young;Soh, Yang-Seob
    • Journal of the Korea Concrete Institute
    • /
    • v.18 no.2 s.92
    • /
    • pp.267-274
    • /
    • 2006
  • Greenhouse gas reduction will be highlighted as the most pending question in the cement industry in future because the production of Portland cement not only consumes limestone, clay, coal, and electricity, but also release waste gases such as $CO_2,\;SO_3$, and NOX, which can contribute to the greenhouse effect and acid rain. To meet the increase of cement demand and simultaneously comply with the Kyoto Protocol, cement that gives less $CO_2$ discharge should be urgently developed. This study aims to manufacture non-sintering cement(NSC) by adding phosphogypsum(PG) and waste lime(WL) to granulated blast furnace slag(GBFS) as sulfate and alkali activators. This study also Investigates the hydration reaction of NSC through analysis of scanning electron microscopy(SEM), X-ray diffraction(XRD), differential thermal analysis(DTA), and pH. Results obtained from analysis of the hydrate have shown that the glassy films of GBFS are destroyed by the activation of alkali and sulfate, ions eluted from the inside of GBFS react with PG and produce ettringite, and consequently the remaining component in GBFS slowly produced C-5-H(I) gel. Here, PG is considered not only to play the role of simple activator, but also to work as a binder reacting with GBFS.

The effect of LED lighting hues on the rating and recognition of affective stimulus (LED 조명색상이 정서자극의 평정과 재인에 미치는 효과)

  • Pak, Hyen-Sou;Lee, Chan-Su;Jang, Ja-Soon
    • Science of Emotion and Sensibility
    • /
    • v.14 no.3
    • /
    • pp.371-384
    • /
    • 2011
  • Three experiments were carried out to examine how LED lighting hues influence to the rating and recognition of affective stimuli. In Experiment 1 and 2, IAPS affective pictures were used and an affective rating(valence and arousal) task and a recognition memory task were conducted under red, green, blue, and white hue LED lightings in Experiment 1 and cyan, magenta, yellow, and white ones in Experiment 2, respectively. In Experiment 3, affective words were used and the same two tasks were conducted under red, green, blue, and white hue LED lightings. According to the results of affective rating tasks, when primary hues(RGB) were used, red LED lighting elicited an excitement at the arousal dimension and green LED lighting evoked pleasantness at the valence one. When secondary hues(CMY) were used, magenta and cyan showed the similar but weaker patterns of responses comparing to red and green. The results of recognition memory task showed that the responses to the picture stimuli presented at green and cyan hue lightings tended to be a bit faster comparing to the stimuli presented at the other conditions but the difference was insignificant. In Experiment 3, however, recognition memory responses to the affective words presented at green hue lighting were faster significantly. These results indicate that warm colors like red and magenta elicit unpleasantness or excitement while cool colors like green and cyan evoke pleasantness or relaxation, and the primary hues provoke more positive or negative affectivity than secondary ones do. Particularly, the result of recognition memory task in Experiment 3 suggests that green hue LED lighting might be advantageous at the memory performance of language stimuli rather than visual ones.

  • PDF

메타인지와 그의 지리교육 적용

  • 임덕순
    • Proceedings of the KGS Conference
    • /
    • 2002.11a
    • /
    • pp.123-126
    • /
    • 2002
  • 교수-학습 방법 발전이 필요하다는 논리와 관련해서 선진국들의 교육 추세를 눈여겨볼 필요가 있다. 첫째, 교육이라는 행위가 교사가 주도하는 교수(teaching, instruction)로부터 학생이 주도하는 학습 (learning)으로 바뀌어 가는 추세이고, 둘째, 학습에 있어서 자극-반응 모델에 기초한 반응에는 강조를 두지 않고 인지(cognition), 즉 지각과 사고를 강조하고 있는 추세이며, 셋째, 따라서 학생이 학습을 제대로 해 가는 데 필요한 여러 가지 방략(strategy), 가령 구성적 방략이나, 비고츠키 모델 등이 개발되거나 원용되고 때로는 기존 방략들(탐구적 방법, 문제해결 방법 등)이 재 강조되면서, 그 방략들이 학생들에게 유효하도록 가르쳐 지고 있는 실정이다.(중략)

  • PDF

A study on the aldehydes concentration in indoor of the residences (일반 주택에서의 실내 aldehydes 농도에 관한 조사 연구)

  • 이지호;양지연;박성은;신동천
    • Proceedings of the Korea Air Pollution Research Association Conference
    • /
    • 2000.04a
    • /
    • pp.259-260
    • /
    • 2000
  • 알데히드류는 실내 가정의 건축물 단열재, 실내가구의 칠, 접착제, 하드보드, 악취 제거제, 제지 등 생활 용품에서 공업용품에 이르기까지 광범위하게 사용되며, 그 사용량도 증가되고 있다. 특히, formaldehyde는 urea-와 Phenol-formaldehyde 수지를 합성하는 주요 화합물질이다. 알데히드류 중 포름알데히드는 1ppm 또는 그 이하의 농도로 노출될 경우, 눈, 코, 목의 자극을 유발하고, 농도에 따라서 피부 알레르기, 두통, 메스꺼움, 흥부 압박감, 기관지염, 폐염 및 폐부종을 야기하며, 동물 실험결과, 미국 환경보호처에서는 인체 발암 가능성 물질로 분류하고 있다(US EPA, 1999). (중략)

  • PDF