• The Journal of Korean Obstetrics and Gynecology
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• v.28 no.1
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• pp.147-157
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• 2015

Objectives: We report two cases that have an effective result with Korean traditional medical treatment to two patients who have uterine fibroids, using transabdominal ultrasonography for checking the size of uterine fibroids. Methods: A 44-year-old patient and a 43-year-old patient were treated with an herbal medicine, acupuncture and cupping therapy. We followed up the symptoms and the size of uterine fibroids. Results: The 44-year-old patient was asymptomatic, her size of the uterine fibroid was reduced for 6 months. Also, the 43-year-old patient experienced that the symptoms such as urinary frequency, ovulation pain, heavy bleeding were improved and the size of the uterine fibroid was reduced. Conclusions: This results suggest that Korean traditional medical treatment if effective for both asymptomatic and symptomatic uterine fibroids and ultrasonography is useful for checking the effect of Korean traditional medical treatment. Further case series and studies are warranted.

• The Journal of Korean Obstetrics and Gynecology
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• v.23 no.4
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• pp.130-145
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• 2010

Purpose: The purpose of this study is to know stress and blood stasis pattern for the patients who had hysterectomy related with uterine myoma, adenomyosis, endometriosis. Methods: We got questionnaires from 55 patients among 243 patients who had hysterectomy related with uterine myoma, adenomyosis, endometriosis in the department of obstetrics and gynecology, OO medical center from April 11th 2010 to October 14th 2010, and analyzed them. We conducted correlation analysis between age, pain(VAS), duration of pain and blood stasis score, and between duration of pain, blood stasis score and the sum of Stress Response Index. We compared the sum of Stress Response Index, blood stasis score, VAS according to the result of pathology. For statistics, we used Pearson's correlation coefficient, Mann-Whitney test, oneway analysis of variances(ANOVA) and SPSS version 17.0 for windows. Results: The correlation between duration of pain and blood stasis score showed statistical significance. The correlation between sum of the Stress Response Index and blood stasis score showed statistical significance. There is no statistically correlation between age, VAS, duration of the pain and blood stasis score. There is no statistically significant difference in sum of Stress Response Index, blood stasis score, VAS according to the result of pathology. Conclusion: The result showed that Stress is related with static blood, and the longer patients suffer from pain, the easier patients' blood to be static. Further study will be needed.

• Tuberculosis and Respiratory Diseases
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• v.60 no.1
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• pp.92-96
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• 2006

A benign metastasizing pulmonary leiomyoma(BMPL) is a rare disease that is usually detected years after a hysterectomy or myomectomy. Despite the benign pathological appearance, these tumors can metastasize and become clinically malignant. Recently, we experienced case of BMPL with hemoptysis. A 43-year-old woman, who had undergone a hysterectomy due to uterine leiomyoma 8 years ago, visited our department complaining of intermittent hemoptysis. A chest CT showed bilateral multiple nodular lesions. Video-associated thoracoscopy was performed. The resected small nodular lesion revealed the proliferation of spindle cells without mitosis or nuclear atypism. The lesions tested positive to the smooth muscle marker (actin) by immunohistochemical staining. Therefore, the multiple nodules were considered as benign metastasizing pulmonary leiomyoma from a uterine leiomyoma. GnRH analogue therapy was initiated. A chest CT showed that the size and number of pulmonary lesions did not change after 3 months, and the patient was symptom free.

• Tuberculosis and Respiratory Diseases
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• v.58 no.6
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• pp.614-618
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• 2005

A benign metastasizing pulmonary leiomyoma (BMPL) is a rare disease that usually occurs in women with a prior or coincident history of uterine leiomyoma. Although leiomyoma is histologically benign, it has the potential to metastasize to a distant site such as the lung. A 35 year old woman who had undergone a hysterectomy due to uterine leiomyoma 5 years prior was admitted for an investigation of multiple pulmonary nodules on a routine chest roentgenogram. An open lung biopsy was taken to make a pathological diagnosis. The microscopic finding of the nodules was leiomyoma and was similar to those of the uterine leiomyoma that had been resected 5 years ago. The woman underwent wedge resections of all pulmonary nodules. This is the first case of BMPL in Korea, which was treated with wedge resections of all multiple pulmonary nodules.

• Journal of the Korean Burn Society
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• v.23 no.2
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• pp.64-67
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• 2020

High-intensity focused ultrasound (HIFU) has been regarded as a non-invasive uterine-preserving treatment for women with uterine myoma. Numerous studies have reported that it is a relatively safe and effective treatment for uterine myoma. However, severe complications, such as deep thermal burn injuries, bowel perforation, and bladder injury, were reported on rare occasions. We report a case of a 4th degree burn on the lower abdomen after HIFU treatment for uterine myoma. Physicians must consider the possibility of deep thermal burn injuries when managing uterine myoma with HIFU.

• The Journal of Korean Medicine
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• v.30 no.2
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• pp.152-165
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• 2009

Objectives: We intended to identify differences of general symptoms related to existence & nonexistence of uterine myoma. Methods: We surveyed 948 women from 35 to 45 years old who had received Korean oriental medical questionnaires about general symptom patterns and abdominal & pelvic ultrasonography at Kyung-Hee University medical center from May 2007 to October 2008. After we divided the women into two (uterine myoma or normal) groups by ultrasonography result, we compared general symptom patterns of the uterine myoma group with those of the normal group. Results: In relation to digestion pattern, appetite showed statistically significant difference between the normal and uterine myoma groups. In relation to evacuation pattern, stool frequency showed statistically significant difference between the normal and uterine myoma groups. In relation to psychologic pattern, difference in oppression in the chest & palpitation showed statistical significance between the groups. In relation to the other patterns, differences in throat discomfort & hypertonicity of nape neck showed statistical significance between the normal and uterine myoma groups (p<0.05). Conclusions: The result showed that prevalence of uterine myoma should be considered in respect to digestion pattern, evacuation pattern, and psychologic pattern. We need further study after increasing the size of the uterine myoma group and improvement of general symptom questionnaires.

• The Journal of Korean Obstetrics and Gynecology
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• v.20 no.4
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• pp.111-122
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• 2007

Purpose: The purpose of this study is to make clear the difference of the mental state between formal menstruation group and menorragia group. Methods: The patients suffering from uterine myoma or adenomyosis answered about menstruation and did a blood test and MMPI. They were analyzed by Mann-Whitney U-test. Results: The D scale of complain of a menorrhagia group is higher than normal menstruation group. (p<0.05) According to blood test, The F scale of anemia group is higher than normal group.(p<0.05) The D scale of menorrhagia with anemia group is higher than normal menstruation without anemia group. (p<0.05) The MMPI score of complain of a menorrhagia group, anemia group, and menorrhagia with anemia group showed 1-2 profile type. The MMPI score of normal menstruation group, normal result of the blood test group, and menorrhagia with anemia group showed 1-3 profile type. Conclusion: regardless of the rxistence of anemia, the group with menorrhagia tends to show a state of depression than the control group.

• The Journal of Korean Obstetrics and Gynecology
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• v.19 no.4
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• pp.159-173
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• 2006

Purpose : The purpose of this study is to find out relation between DSOM scores and an attack of uterus myoma in oriental medicine. Methods : We analyze the medical records for 386 patients including 257 uterus myoma patients who visited Dongeui University Oriental Medical Center from May 2001 to June 2006. We investigate the DOSM symptom scores which effect uterus myoma patients using logistic regression model. Results : Logistic regression analysis indicate that 14 items of DSOM were associated with the myoma, and the results show that correct rate is equal to 79.79%, sensitivity is 83.66%, specificity is 72.09%. Conclusion : There is fair relation between DSOM scores(14 items of DSOM) and an attack of uterus myoma in oriental medicine.

• The Journal of Korean Obstetrics and Gynecology
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• v.21 no.2
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• pp.27-37
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• 2008

Purpose: This study was conducted to investigate the effects of Ginseng Radix Alba extract solution on the cell cycle regulation, apoptosis of human uterine myoma cells. Methods: Primary cultured human uterine myoma cells were treated with extract solution of Ginseng Radix Alba concentration of 1, 10 and $100mg/m{\ell}$ for 48 hours. We underwent flow cytometry and western blotting for cell cycle and apoptosis related factors. Results: In flow cytometry, a slight promotion of G1 phase in $1mg/m{\ell}$ group had been observed but, simultaneously a delay of G1 phase in 10 and $100mg/m{\ell}$ groups were also observed. The manifestation of cyclin D1 in Ginseng Radix Alba extract solution medicated group increased compared to the control group. The manifestation of Bax controlling apoptosis increased in terms of concentration but Bcl-2 showed no change. Also VEGF increased in terms of concentration. Conclusion: The present study suggests that Ginseng Radix Alba extract solution treatment in human uterine myoma cells induce the delay of cell cycle and apoptosis. These results suggest that Ginseng Radix Alba will be a promising agent for use in therapeutics agents against human uterine myoma.

• Journal of Chest Surgery
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• v.43 no.5
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• pp.525-528
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• 2010

Congenital interruption of the inferior vena cava (IVC) can lead to secondary hepatic congestion, portal hypertension, and liver cirrhosis. A 49-year-old woman was admitted to the gynecology department with symptoms of menorrhalgia, known uterine myoma, and anemia. Abdominal computed tomography (CT) and venography performed at our hospital revealed congenital interruption of the IVC. The patient underwent retrohepatic cavoatrial bypass surgery with a polytetrafluoroethylene (PTFE) 16-mm ringed graft via posterolateral thoracotomy, and recovered without major complications. A retroperitoneal approach via posterolateral thoracotomy provides appropriate visualization during dorsal cavoatrial bypass in treating patients with congenital interruption of IVC.