Tuberculosis and Respiratory Diseases

The Korean Academy of Tuberculosis and Respiratory Diseases (대한결핵및호흡기학회)
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Benign Metastasizing Pulmonary Leiomyoma with Hemoptysis

객혈을 동반한 양성 전이성 폐 평활근종 1예

  • Park, So Young (Department of Internal Medicine, College of Medicine, Hallym University) ;
  • Lim, Eun Ju (Department of Internal Medicine, College of Medicine, Hallym University) ;
  • Jang, Ji-Sun (Department of Internal Medicine, College of Medicine, Hallym University) ;
  • Kim, Chang-Hwan (Department of Internal Medicine, College of Medicine, Hallym University) ;
  • Jee, Hyun Keun (Department of Thoracic surgery, College of Medicine, Hallym University) ;
  • Cho, Sung Jin (Department of Anatomical Pathology, College of Medicine, Hallym University) ;
  • Park, Yong Bum (Department of Internal Medicine, College of Medicine, Hallym University) ;
  • Lee, Jae Young (Department of Internal Medicine, College of Medicine, Hallym University) ;
  • Mo, Eun Kyung (Department of Internal Medicine, College of Medicine, Hallym University)
  • 박소영 (한림대학교 강동성심병원 내과) ;
  • 임은주 (한림대학교 강동성심병원 내과) ;
  • 장지선 (한림대학교 강동성심병원 내과) ;
  • 김창환 (한림대학교 강동성심병원 내과) ;
  • 지현근 (한림대학교 강동성심병원 흉부외과) ;
  • 조성진 (한림대학교 강동성심병원 해부병리과) ;
  • 박용범 (한림대학교 강동성심병원 내과) ;
  • 이재영 (한림대학교 강동성심병원 내과) ;
  • 모은경 (한림대학교 강동성심병원 내과)
  • Received : 2005.07.20
  • Accepted : 2005.11.04
  • Published : 2006.01.30
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Abstract

A benign metastasizing pulmonary leiomyoma(BMPL) is a rare disease that is usually detected years after a hysterectomy or myomectomy. Despite the benign pathological appearance, these tumors can metastasize and become clinically malignant. Recently, we experienced case of BMPL with hemoptysis. A 43-year-old woman, who had undergone a hysterectomy due to uterine leiomyoma 8 years ago, visited our department complaining of intermittent hemoptysis. A chest CT showed bilateral multiple nodular lesions. Video-associated thoracoscopy was performed. The resected small nodular lesion revealed the proliferation of spindle cells without mitosis or nuclear atypism. The lesions tested positive to the smooth muscle marker (actin) by immunohistochemical staining. Therefore, the multiple nodules were considered as benign metastasizing pulmonary leiomyoma from a uterine leiomyoma. GnRH analogue therapy was initiated. A chest CT showed that the size and number of pulmonary lesions did not change after 3 months, and the patient was symptom free.

자궁근종으로 자궁절제술을 시행받은 과거력이 있는 43세 여자가 객혈을 주소로 내원하였다. 컴퓨터단층촬영에서 다발성 폐결절이 발견되어 흉강경하에서 조직검사 시행 후 양성 전이성 폐평활근종을 진단받았다. 폐경 전 환자로 GnRH analogues 치료를 시도하였고 3개월 후 추적검사에서 폐결절의 크기는 이전과 변화가 없는 상태를 확인하였고 객혈도 없는 안정된 상태로 경과 관찰중이다.

Keywords

References

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