• Polymer(Korea)
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• v.37 no.3
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• pp.387-392
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• 2013

The aim of this study was to investigate the effect of trasdermal delivery of the curcumin gel on healing of the rats' dorsum wounds. Carbopol 934 and propylene glycol were used to prepare gels containing 1% curcumin. Curcumin gel was evaluated for various properties such as antioxidant, cell viability, anti-inflammatory, in vivo wound healing. The free radical scavenging activity using 1,1-diphenyl-2-picryl hydrazyl (DPPH) was 50% at 12.5 ppm concentration. Inhibition of nitric oxide (NO) production in lipopolysaccharide (LPS)-stimulated RAW 264.7 cells by curcumin gel. In the curcumin gel-treated group, the re-epithelialization in wounds was significantly increased compared to the control group throughout the experimental period. These results suggested that curcumin may be helpful for the promotion of wound healing.

• Korean journal of communication and information
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• v.74
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• pp.38-71
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• 2015

Based on the Foucault's governmentality, this study has described the self-government strategy that healing discourse is implemented during 2011-2013. Healing discourse's priority is the existence value of individual and full concentration about self is needed more than anything. In this process, people who need to heal and comfort are limit to de-politicized individuals. Healing discourse emphasizes that the current enhancement in order to become reflection and growth of self. Demands of reflection and growth is substitute the critics of the era and society, but also act as a specific code of conduct to individuals. While emphasizes the reflection and personal growth, healing discourse has top priority of the current value. However, in this process, criticism of the era issues and social structural factors are fundamentally excluded. People accepted healing discourse actively, decided empowering self by reflection and remorse. On the other hand, there is a crack and specificity in the dominant reception discourse likewise some subjects criticized that there is no realistic consolation, exposed the antipathy to the older generation, denied the way of problematized objectification. But this is a partial denial about healing as concrete technology, not fundamental resistance about neoliberal orders.

• Korean Journal of Head & Neck Oncology
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• v.30 no.2
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• pp.43-52
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• 2014

배경 및 목적 암-연관 섬유아세포(Cancer-associated fibroblasts, CAF)는 종양미세환경의 가장 중요한 요소의 하나다. 그래서 두경부편평세포암에 대해 CAF가 암세포의 운동성에 미치는 영향을 평가하고, CAF에 과발현되는 CD44의 역할에 대해 평가하고자 하였다. 재료 및 방법 두경부암환자의 종양조직에서 CAF를 분리하고, 비종양성 조직으로부터 정상 섬유아세포(NHF)를 분리하였다. 창상치유분석과 상하 챔버를 이용한 3차원 세포 이동 분석을 이용하여, CAF가 암세포의 이동에 미치는 영향을 분석하고, CAF에서 과발현되는 CD44를 중화항체로 CAF를 차단했을 때 암세포 이동의 변화를 관찰하였다. 결과 NHF에 비해 CAF에서 CD44가 과발현되는 것을 관찰하였다. 창상치유분석에서 CAF와 같이 배양된 암세포는 NHF와 같이 배양된 암세포에 비해 더 빠른 이동을 보였다. CD44 중화 항체를 처리했을 때는 암세포의 이동성이 저해되었다. 결론 CAF는 종양미세환경에서 암세포의 운동성을 조절하는 중요한 인자의 하나일 것으로 사료된다. CD44는 CAF의 기능을 매개하는 중요한 표지자 중 하나로 생각된다.

• Journal of The Korean Society of Integrative Medicine
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• v.10 no.4
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• pp.261-275
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• 2022

Purpose : According to the Korean Diabetes Association, the number of metabolic disease patients in Korea is approximately 14.97 million as of 2020;, the prevalence of diabetes among adults over 30 years old is 44.3 %, and the prevalence of diabetes in the elderly over 65 years old is 50.4%. These individuals exposed to the risk of complications. Therefore, the purpose of this study was to determine a distribution method for a customized fusion exercise marine healing program for metabolic disease patients. Methods : We have searched numerous papers concerning artificial intelligence (AI), virtual reality (VR), augmented reality (AR), and marine resources related to marine healing programs that can be introduced in marine healing centers for people with metabolic diseases Results : Through the production of various marine resources and evidence-based exercise programs, the provision of exercise programs using AI, and the development of exercise platforms using AR and VR, we were able to establish guidelines for how to operate marine healing programs at marine healing centers. Conclusion : Korea has much more diverse marine healing resources than other advanced countries in the marine healing industry. However, the development of these resources has only just begun. It is hoped that the studied marine healing program will be of great help to metabolic patients by creating contents that will be implemented in marine healing centers by using the cutting-edge technologies and various marine resources that Korea possesses.

• Proceedings of the Korean Institute of Building Construction Conference
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• 2022.11a
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• pp.241-242
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• 2022

Recently, related studies on the application of bacterial spores to self-healing concrete have been widely reported. Using the self-healing method of bacterial spores as a kind of pro-environment, the green method is very attractive, but because the living environment of bacterial spores is relatively harsh, it is necessary to have a way to separate the living environment of bacterial spores from the harsh external environment, And release bacterial spores when needed. Therefore, capsules are widely used in self-healing concrete. To enhance the self-healing effect, the capsules need to be evenly distributed in the concrete. Furthermore, we develop a CIP-based smart capsule with controllability. We determined the magnetic force of each capsule by mixing CIP in resin, then mass-fabricating the capsules for self-healing by a microfluidic method, and by measuring the kinetic distance of the capsules containing different amounts of cip under the action of a magnetic field strength. The results show that with the increase of the amount of cip, the active distance of the capsule also increases. When the cip is 8wt%, the active distance reaches 1.75cm. We believe this research can provide momentum for the development of self-healing capsule applications.

• Sim-seong Yeon-gu
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• v.30 no.2
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• pp.111-144
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• 2015

Chilseongpul-i is a Korean shamanic myth in which the life story full of hardships of seven sons is told, until they will take up the sacredness of Chilseong god. The seven sons, who were born from Chilseongnim and his wife Okneobuin, are abandoned by their father, Chilseongnim. But sometime later they are born with new characters after going through a special growth process of suffering, dying, and rebirth. They finally recover the sacred position to save their mother. As considered by the analytical psychology, the fact that the seven sons became Chilseong gods shows an individuation process of the heroic mythology. The individuation process might be regarded as a symbol of Self-archetype of Koreans. Self-archetype functions as a healing which gets one's split heart and mind together. An imago dei of healers should be projected upon the seven gods by ancestors.

• Journal of Veterinary Clinics
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• v.16 no.1
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• pp.95-99
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• 1999

돼지 심장의 해부학적 구조에 대해서는 많은 연구가 보고되어 있으나 흉골 정중선 절개와 방정중선 절개 후 절개선에 나타나는 돼지 심장 대혈관들의 외과적 해부구조에 대한 보고는 아직 없고 심장적출 및 수술에 외과적 해부구조의 숙지가 필수적이므로, 체중 15kg - 25kg의 돼지 12마리를 4마리씩 3군, 즉 정중선절개군, 우측방정중선절개군, 좌측방정중선절개군으로 나누어 흉골열개 후 나타난 심장 대혈관들의 육안적 외과구조를 보고하고 심장적출술을 시도해 각 수술절개 접근법에 따른 수술의 용이성을 관찰하여 더 나은 수술접근법을 선택하는데 필요한 정보를 제공하고자 본 실험을 실시하였다. 그 결과, 우측과 좌측 방정중선절개법에 의해 흉골을 완전 열개시에는 제 1흉골과 갑상연골 부위에서 정중선으로 접근하는 초승달형 절개를 통해 internal mammary artery의 절개 위험성을 피할 수 있음을 발견하였고 흉골정중선절개에서는 상행대동맥의 정 중앙부에 aortic cannula를 쉽게 장착할 수 있었고 특히 비숙련자에게 더 적절한 수술 방법임을 알 수 있었다. 한편 숙련자가 심장적출이 아닌 동맥관개존증등과 같은 심장수술의 경우에는 방 정중선절개로써 환축의 수술 후 통증을 감소시키고 조기치유가 가능하다면, 초승달형 절개법을 응용한 방정중선 절개를 권할 수 있고 이에 따른 임상적 관찰이 요구되는 바이다.

• Journal of Trauma and Injury
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• v.28 no.1
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• pp.21-26
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• 2015

Complete radial tears of the lateral meniscus are relatively rare. Once torn, the injury can be debilitating due to disruption of the circumferential fibers of the meniscus. We experienced a case of a lateral meniscus with a complete radial tear at the midbody, where the two torn ends were displaced more than 1 cm and could not be approximated during arthroscopy. Thirteen months after surgery, follow-up MRI and second-look arthroscopic findings showed that the complete radial tear has healed spontaneously. However, twenty nine months after the second-look arthroscopy, the patient complained of severe knee pain during exercise. On follow-up MRI, increased sclerosis and newly developed bone marrow edema were observed in the lateral femoral condyle, compared with previous MR images. Finally, we performed meniscal allograft transplantation due to the defective properties of the completely healed lateral meniscus.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• v.33 no.6
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• pp.654-659
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• 2007

We performed sinus bone graft using some amount of autogenous bone and $BioOss^{(R)}$ and covered the sinus window with $Ossix^{(R)}$ membrane in these case series. After 4 to 6 months after operation, histopathologic examinations of trephine core biopsy showed following results. 1. There were bone density of 39.2% to 41.2% four months after operation, and we could observe the favorable early new bone formation. 2. Active bony remodeling of woven and lamellar bone was observed during 4 to 6 months healing period. 3. There were no significant differences between two groups. And also there were no significant differences between 4 months and 6 months.

• Korean Journal of Veterinary Research
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• v.45 no.2
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• pp.273-278
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• 2005

This study was investigated of the bone healing capacity by autologous fibrin glue in experimental bone defect dogs. The autologous fibrin glue manufactured just before the experiment was mixed with the concentrated fibrinogen from whole blood of the experimental dog and bovine thrombin. The experimental group was constituted with seven dogs. The experimental osteotomy was performed 5 mm length in bilateral region of proximal diaphyseal fibulae. The defected regions of experimental group were filled with the autologous fibrin glue by duploject. The experimental regions had been radiographed biweekly for 16 weeks to observe new bone formation and union. Bone alkaline phophatase (BALP) in all groups was evaluated biweekly till the end of the experiment to determine osteoblast activities. New bone formation had been observed in five regions of three dogs at four weeks after the experimental treatment and in two regions of one dog at ten weeks. The other seven regions of the experimental group and control group were not observed new bone formation until the end of the experiment. BALP value in four dogs observed new bone formation was increased to 97.10 IU/L (453.96%) at two weeks after the experimental treatment. The results of this experiment were suggested that the autologous fibrin glue was moderately effective in new bone formation in dogs.