• Journal of Chest Surgery
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• v.32 no.1
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• pp.92-95
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• 1999

The patients with prolonged air leak after lung resection surgery were generally treated by pleurodesis with sclerosing agents such as talc, tetracyclin, doxycyclin, bleomycin, vibramycin, and OK432. However, for the case like dead space resulted by incomplete reexpansion of the remaining lung, chemical pleurodesis has shown to be not as effective as expected. If the patients keep the chest tube for long period of time, the risk of thoracic empyema would increase. Most thoracic surgeons have experienced prolonged airleak which developed after lung resection. Pleurodesis with autoblood was reported as an effective method in treatment of patients with prolonged airleak. The mechanism of blood pleurodesis may be direct obliteration of BPF and reduction of dead space by clot. Therefore we successfully treated the two patients with prolonged airleak using the autoblood plus OK432 or vibramycin.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.18 no.11
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• pp.357-366
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• 2017

This study was conducted to identify the diabetes self-care (DSM) knowledge, DSM competence, DSM behavior, and quality of life according to HbA1c control in diabetic elderly. The participants were 205 diabetes elderly who visited the citizen health promotion center located in D city, Korea. Data were collected from April, 4 to August 31 2015, and were analyzed by the t-test and chi-squared test using IBM SPSS 23.0. The mean scores of DSM knowledge, DSM competence, DSM behavior and quality of life were $50.61{\pm}16.39$, $71.27{\pm}10.21$, $62.78{\pm}1.29$ and $0.86{\pm}0.11$, respectively. Additionally, DSM behavior (t=2.17, p=0.031), education level (t=11.80, p=0.0019) l, BMI (t=0.001, p=0.012), and number of visits to citizen health center (t=16.497, p=0.001) differed significantly between the controlled HbA1c group and uncontrolled HbA1C group. However, ANCOVA revealed that the level of HbA1c did not affect the DSM behaviors. Therefore, it is necessary to develop and apply a DSM education program that reflects the characteristics knowledge level of the elderly. In addition, healthcare institutions with high accessibility in terms of distance and cost to guide and manage desirable diabetic self-care behaviors should be provided everywhere.

• Clinical and Experimental Pediatrics
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• v.51 no.2
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• pp.214-218
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• 2008

Neuroblastoma is one of the most common extracranial solid tumor of childhood, and treatment of refractory neuroblastoma remains a significant clinical problem. Iodine-131-metaiodobenzylguanidine ($^{131}I-MIBG$) therapy is an alternative approach to treat stage IV neuroblastoma. We report the palliative effect of $^{131}I-MIBG$ in three cases of relapsed neuroblastoma after autologous peripheral blood stem cell transplantation. $^{131}I-MIBG$ is an effective and relatively nontoxic palliative therapy resulting in reduction of pain and prolongation of survival.

• Journal of the Korea Convergence Society
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• v.12 no.3
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• pp.389-399
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• 2021

This study is the quasi-experimental research of nonequivalent groups and is designed to investigate the effects of an aquatic exercise program with diabetes self management education on the self care efficacy, self care behaviors in diabetic patients in community. The subjects of this study were 26 patients in the experimental group who participated in the aquatic exercise program and 25 patients in the control group who did not paricipated in. And they were registered at the W Health Clinic in D city. The aquatic exercise program was conducted twice a week for 80 minutes, and consisted of a 30 minutes diabetes self management education and a 50 minutes aquatic exercise. After this program, there were significant differences in FBS(p=.047), HbA1c(p<.001), diabetes self efficacy(p<.001), and self care behaviors(p<.001). In order to reduce the prevalence of diabetes and prevent complications in the community, it is believed that the constant operation of aquatic exercise programs including self management education is necessary.

• Proceedings of the Korea Information Processing Society Conference
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• 2013.11a
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• pp.1474-1475
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• 2013

부항은 열 또는 음압(陰壓)장치에 의하여 부항단지 안에 음압을 조성하여 피부에 붙임으로써 피를 뽑거나 울혈(鬱血)을 일으키며 물리적 자극을 주어 병을 치료한다. 부항으로 얻어지는 물리적인 자극은 혈액순환을 촉진하고, 죽은피를 빼냄으로써 혈관을 자극하고 그로인해 다양한 효과를 얻는다. 따라서 본 논문에서는 신장에 해당하는 명문혈을 자극하여 신장과 관련된 음성분석 요소의 변화를 측정하였다. 이를 위해 신장에 이상이 없는 피실험자 10명을 선정하고 신장에 해당하는 명문혈을 자극하기 전과 후의 음성을 수집하였다. 실험은 음성분석 요소 중 신장과 관련된 1 Formant Bandwidth를 적용하여 신장 명문혈 자극 전과 후의 변화를 측정, 분석하였다. 실험 결과, 90%의 피실험자가 값이 감소하는 현상을 보였으며, 이를 통해 명문혈 자극에 따른 신장과 음성신호와의 상관성을 분석할 수 있었다.

• Journal of Korean Biological Nursing Science
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• v.12 no.2
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• pp.106-113
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• 2010

Purpose: This study is conducted to examine the relationship among self management, HbA1c, and perceived health status of type II diabetes patients in community health department. Methods: Data were collected from 93 type II diabetes patients who are registered at five community health center using comprehensive survey, modified self care behavior, blood glucose and HbA1c were assessed by nurses. The data was analyzed by the SPSS (14.0) computer program, and it included descriptive statistics, t-test, ANOVA, and pearson's correlation coefficient. Results: There was significant relationship between perceived health status and HbA1c (r=-.252, p=.015). There was significant relationship between self management and HbA1c (r=-.279, p=.007). Conclusion: In order to control blood glucose in the type II diabetes patients, it is necessary to develop supportive self management programs by considering perceived health status.

• Journal of Acupuncture Research
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• v.27 no.4
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• pp.55-65
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• 2010

목적 : 기존 연구에서 신문혈 자침은 알코올 및 코카인을 자가섭취하는 동물 모델에서 효과적이라는 점이 밝혀졌으며, 또한 모르핀 자가섭취를 억제할 수 있음이 밝혀졌다. 이러한 결과를 바탕으로 본 연구에서는 자침의 효과가 얼마나 지속될 수 있는지 알아보았다. 재료 및 방법 : 체중 270~300g의 수컷 SD계 흰쥐를 이용하였다. 먹이섭취 훈련을 통과한 후 오른쪽 경정맥에 관을 삽입하는 수술을 거쳐, 0.1mg/kg의 모르핀을 매일 1시간, 총 3주 동안 자가섭취 하도록 하였다. 모르핀을 일정하게 섭취한 동물에게는 다음날 침술을 시행하였다. 두 번째 실험에서는 GABAA 및 GABAB 길항제를 자침 30분 전에 투여하여 침술의 효능과 GABA 수용체계 사이의 관계를 검증하였다. 결과 : 모르핀 자가섭취를 억제하는 신문혈 자침의 효과는 매일 비슷하게 나타나지 않았으며, 4일째에는 유의한 효과가 없는 것으로 나타났다. 그러나 5일째와 6일째에는 다시 유의한 효과가 나타나 뒤집어진 U 자형 곡선을 나타내었다. 또한 GABA 수용체의 길항제들은 자침의 효과가 유의하게 나타났을 때 이를 차단하는 결과를 보였다. 결론 : 모르핀 중독 치료에서 침술의 효과는 항상 비슷하게 발휘되는 것이 아니므로 침 치료는 적어도 1주일에 2회 이상 받을 필요가 있다. 아울러 보다 심도 있는 연구를 위하여 뇌신경 체계에 대한 연구가 이루어질 필요가 있는 것으로 사료된다.

• Journal of agricultural medicine and community health
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• v.47 no.2
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• pp.67-77
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• 2022

Objective: This study was to evaluate the effectiveness of an individually tailored program based on self-measurement of blood glucose on health behavior and HbA1c in diabetes and pre-diabetes patients. Methods: The program consisted of seven sessions for 12 weeks which were carried out every two weeks. Almost all sessions were progressed on untact method except for the first and last session. The 71 subjects were assessed for their knowledge of diabetes, health behavior, the experience of self-measurement of blood glucose, body mass Index (BMI) and hemoglobin A1c (HbA1c) at before and after the program. They were also evaluated on their degree of utilization of blood glucose measurements after the program. Results: Each mean score on their knowledge of diabetes, health behavior and the experience of self-measurement of blood glucose was significantly increased from 14.77, 25.50, and 2.70 to 15.41, 28.40, and 4.81, respectively. Each mean score on both BMI and HbA1c (n=53) was significantly decreased from 24.47kg/m² and 7.27% to 24.01kg/m² and 6.67%, respectively. The post-HbA1c had a significant negative correlation(r=-0.415) with the degree of utilization of blood glucose measurements. The degree of utilization of blood glucose measurements had a significant positive correlation(r=0.581) with post-health behavior. Conclusions: The program shows effectiveness in improving HbA1c in Type 2 diabetes and pre-diabetes patients. The post-HbA1c might be related to the degree of utilization of blood glucose measurements which might be related to the health behavior.

• Clinical and Experimental Pediatrics
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• v.50 no.9
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• pp.882-890
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• 2007

Purpose : Preterm very low birth weight infant have high rate of adverse neurodevelopmental sequale. Recently, there have been lots of reports that human umbilical cord blood transplantation ameliorates functional deficits in animal models as hypoxic ischemic injury. This pilot study was undertaken to determine the clinical efficacy and safety of autologous umbilical cord blood cell transplantation for preventing neurodevelopmental sequale in perterm VLBW. Methods : Subjects were 26 preterm infants whose birth weight are less than 1,500 g and delivered under the intrauterine period 34 weeks. Autologous umbilical mononuclear cells (about $5.87{\times}10^7/kg$) were injected to neonate via the umbilical vein on the postnatal 24-48 hour. The therapeutic efficacy was assessed by numbers of nucleated RBC, urinary uric acid/creatinine ratio, concentration of neuron specific enolase (NSE), interleukin 6 (IL6), interleukin-$1{\beta}$ ($IL-1{\beta}$), and glial cell derived neurotrophic factor (GDNF) in serum and cerebrospinal fluid on day 1 and 7. Results : There were no significant differences in the numbers of the nucleated RBC, urinary uric acid/creatinine ratio, concentration of creatine kinase between the transplanted infants and controls. But the nucleated RBC is more likely to be rapidly discharged in the transplanted group. In the transplanted group, the concentrations of IL6, $IL-1{\beta}$, and GDNF were no significant difference between day 1 and 7, although GDNF seemed to be elevated. Serum NSE concentration was significantly elevated after transplantation, but not in CSF. Conclusion : It is suggested that autologous umbilical cord blood transplantation in preterm very low birth weight infant is safe to apply clinical practice. Long term follow up study should be needed to evaluate the potential therapeutic effect of umbilical cord blood transplantation for neuroprotection.

• The Monthly Diabetes
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• s.219
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• pp.8-10
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• 2008

당뇨병환자가 혈당을 잘 조절해야 하는 가장 큰 이유 중 하나는 당뇨병으로 인해 발생하는 합병증을 예방하고 진행을 늦추는 것입니다. 당뇨병환자가 혈당을 정상에 가깝게 조절을 하면 만성 합병증의 발생을 예방할 수 있고, 발생한 합병증의 진행을 늦출 수 있다는 연구 보고들이 많이 있습니다. 그렇다면 어느 정도 혈당수치가 되어야만 혈당조절이 잘 되었다고 할 수 있을까요? 즉 당뇨병환자의 목표 혈당수치는 얼마일까요? 목표 혈당수치는 공복 혈당, 식후 혈당, 취침전 혈당이 각각 다릅니다. 당화혈색소는 혈당수치는 아니지만 공복이나 식후 혈당과는 달리 2$\sim$3개월간의 혈당수치를 반영하므로 혈당조절이 잘되고 있는지를 알아보는 지표로 많이 이용하고 있습니다. 공복혈당은 80$\sim$120mg/dL, 식후 2시간 혈당은 160mg/dL 미만, 취침전 혈당은 100$\sim$140mg/dL를 유지하는 것을 권장하고 있으며, 당화혈색소는 7% 이하 가능하다면 6.5% 까지 유지하는 것을 목표로 합니다. 더 나아가서 당뇨병으로 인한 만성 합병증을 예방하려면 혈당조절뿐만 아니라 혈압, 콜레스테롤도 잘 조절해야 합니다. 혈압은 130/80mmHg 이하로 유지해야 하며 우리 몸에 좋은 콜레스테롤(HDL)은 남자는 40mg/dL 이상, 여자는 50 mg/dL 이상 되어야 하고, 우리 몸에 나쁜 콜레스테롤(LDL)은 100mg/dL 이하, 중성지방은 150mg/dL 이하로 유지해야 합니다. 물론 금연을 하여야 하고 음주를 해서는 안되겠습니다.