• Title/Summary/Keyword: 임상 경과

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$^{99m}Tc$-DMSA Scintigram for Renal Function Recovery after Therapy in Infants and Children (유소아 신질환에서 치료후 신기능회복에 대한 $^{99m}Tc$-DMSA 신티그램의 임상적 고찰)

  • Moon, Tae-Yong;Son, Hyun-Ju;Kim, In-Ju;Yoon, Chong-Byung;Lee, Suck-Hong;Kim, Byung-Soo
    • The Korean Journal of Nuclear Medicine
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    • v.28 no.1
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    • pp.69-74
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    • 1994
  • Authors retrospectively analysed 20 cases of follow-up $^{99m}Tc$-DMSA renal scans to evaluate renal function recovery after treatment in urologic disorders of infants and children. There were 20 cases with both $^{99m}Tc$-DMSA renal scans prior to and after therapy in 15 patients below 9 years old. Among them, 10 patients underwent ureteroneocystostomy under the diagnosis of vesicoureteral reflux, two patients pyeloplasty because of obstructive uropathy and one was treated with antibiotics even diagnosis of UPJ stricture. We have got the quantified uptake rate of $^{99m}Tc$-DMSA renal scan by using the regression equation as "y=0.591x-2.105" (y=the quantified uptake rate, x=the simple uptake rate). The number of kidneys performed proper therapy were 29, and the cases with more increased radiotracer uptake rate in the follow-up $^{99m}Tc$-DMSA renal scans were 20 in number as 69% in frequency. 19 cases with improved renal function on $^{99m}Tc$-DMSA renal scans didn't show any significant difference related to aging or recovery duration after therapy. The $^{99m}Tc$-DMSA renal scans were not useful to evaluate renal function recovery in infants and children, but could be good tests to assess residual renal function prior to or after treatment.

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Development and Application of the Automatic System for Preparing Input Parameters in PRMS (PRMS 모형의 입력 매개변수 자동화 추출 시스템 개발 및 적용)

  • Hwang, Eui-Ho;Kwon, Hyung-Joong;Yoo, Byung-Hyuk;Koh, Deuk-Koo
    • Proceedings of the Korea Water Resources Association Conference
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    • 2007.05a
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    • pp.459-463
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    • 2007
  • 본 연구에서는 기존 유출분석의 입력자료 생성 시 발생되는 사용상의 불편함과 다양한 수질 수문 모형에 적용을 위한 유역특성자료 도출 기반의 미비로 인하여 보다 편리하고 체계적인 유역특성자료 분석 시스템을 개발하고자 하였다. 기존 PRMS를 이용하여 유출분석 시 입력자료 생성을 위해 사용되는 USGS WEASEL 벤치마킹을 통하여 시스템 개발항목을 도출하고, 체계적이고 효율적인 시스템 개발 및 유지관리를 위하여 UML을 이용한 객체지향 시스템 설계를 수행하였다. 또한, 편리한 사용자 인터페이스 제공 및 다양한 수질 수문 모형에 적용하기 위한 GIS 컴포넌트 기반인 ArcGIS ArcObject를 이용한 시스템 개발을 수행하였다. 또한, 시범 연구지역인 용담댐 유역을 대상으로 DEM, 토양도, 토지피복도, 임상도 등을 구축하여 유역특성자료 분석 시스템에 적용하여 PRMS의 입력 매개변수를 추출하였다. 본 연구에서 개발한 시스템에 의하여 추출된 매개 변수의 검토를 위하여 용담댐 유역과 구량천 유역을 대상으로 PRMS를 이용한 장기유출모의를 수행하였다. 강우자료 및 기상자료는 기상청의 장수기상관측소의 시계열 자료를 사용하였으며 모의 결과를 검증할 수 있는 하천유출량 자료는 용담댐 지점과 동향수위관측소 자료를 사용하였다. 장기유출모의 목적에 맞는 PRMS 모형을 구성하고 유역특성자료 분석시스템을 이용하여 추출된 매개변수로서 1966년부터 2001년까지 용담댐 유역에 대하여 모의하여 매개변수를 최적화하였고 최적화된 매개변수를 이용하여 각각의 유역에 대하여 검토하였다. 그 결과 용담댐 유역에 대해서는 0.49에서 0.83까지의 모형효율을 나타내었으며 구량천 유역에 대해서는 0.57에서 0.75까지의 모형효율을 나타내어 모의결과가 실측치에 대하여 높은 적합도를 나타내었다.997년 이후로 지속적으로 감소되고 있다.게 될 것이다. 본 연구에서는 현재 진행중인 승기천 오염하천 정화사업이 종료되는 시점을 기준으로 남동유수지에 대해 승기천과 연계한 유수지의 환경개선 방법을 제안하였다. 준설을 통해 유수지의 근본적인 오염원을 제거하고 남동유수지 유입부에 인공습지와 수처리설비를 설치하여 유수지의 수질을 개선하고 개선된 수질이 3급수로 유지하도록 하였으며, 설치된 인공습지에는 철새도래지를 조성하여 유수지 유입수인 철새가 날아드는 하천인 승기천의 테마와 연계하도록 하였다. 인공습지 주변으로 식생호안을 설치하고 유수지 주변에는 산책로를 설치하여 지역주민들의 친환경 수변공간으로 활용하도록 하였다. 1유수지와 연결된 2유수지는 BTL사업을 통해 주변공단으로부터의 오폐수를 원천적으로 차단하도록 하였으며 2유수지를 매립하여 지하는 강우시 유출수 저류가 가능한 화물차주차장으로 활용하고 지상은 녹지공간으로 조성하여 공단근로자 및 지역주민을 위한 휴식공간으로 활용될 수 있도록 제안하였다. 본 연구는 남동유수지 환경 개선 사업 실행을 위한 정책 연구로 연구결과를 인천시가 적극 수용하기로 결정함에 따라 인천시의 환경 현안 문제인 남동유수지의 수질개선을 통해 시민의 휴식 및 여가선용 공간으로 활용하기 위한 사업의 기초자료로 활용되며 이미 설계검토가 시작되었다. 본 연구결과는 유수지 및 저수지의 환경개선 사업의 선두적인 성공사례로 국내 타 지역의 유사한 사업에 있어 벤치마킹을 할 수 있는 훌륭한 사례가 될 것이다.요 생산이 증가하자 군신의 변별(辨別)과 사치를 이유로 강력하게 규제하여 백자의 확대와 발전에 걸림돌이 되었다. 둘째, 동기(銅器)의 대체품으로 자기를 만들어 충당해야할 강제성 당위성 상실로 인한 자기수요 감소를 초래하였을 것으로 사료된다. 셋째, 경기도 광주에서

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The Effectiveness of Electroglottographic Parameters in Differential Diagnosis of Laryngeal Cancer (후두암 감별진단에 있어 성문전도(Electroglottograph) 파라미터의 유용성)

  • 송인무;고의경;전경명;권순복;김기련;전계록;김광년;정동근;조철우
    • Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
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    • v.14 no.1
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    • pp.16-25
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    • 2003
  • Background and Objectives : Electroglottography(EGG) is a non-invasive method of monitoring the vocal cord vibration by measuring the variation of physiological impedance across the vocal folds through the neck skin. It reveals especially the vocal fold contact area and is widely used for basic laryngeal researches, voice analysis and synthesis. The purpose of this study is to investigate the effectiveness of EGG parameters in differential diagnosis of laryngeal cancer. Materials and Methods : The author investigated 10 laryngeal cancer and 25 benign laryngeal disease patients who visited at the Department of Otolaryngology, Pusan National University Hospital. The EGG equipment was devised in the author's Department. Among various parameters of EGG, closed quotient(CQ), speed quotient(SQ), speed index(SI), Jitter, Shimmer, Fo were determined by an analysis program made with MATLAB 6.5$^{\circledR}$(Mathwork, Inc.). In order to differentiate various laryngeal diseases from pathologic voice signals, the author has used the electroglottographic parameters using the neural network of multilayer perceptron structure. Results : SQ, SI, Jitter and Shimmer values except those of CQ and Fo showed remarkable differences between benign and malignant laryngeal disease groups. From the artificial neural network, the percentage of differentiating the laryngeal cancer was over 80% in SQ, SI, Jitter, Shimmer except for CQ and Fo. These results indicated that it is possible to discriminate the benign and malignant laryngeal diseases by EGG parameters using the artificial neural network. Conclusion : If parameters of EGG which can reveal for the pathology of laryngeal diseases are additionally developed and the current classification algorithm is improved, the discrimination of laryngeal cancer will become much more accurate.

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Perception of Artificial Hydration for Terminally Ill Cancer Patients: Patients, Families and General Public (말기 암 환자에서의 정맥 내 수액요법에 대한 인식도: 환자, 보호자 및 일반인)

  • Yang, Seong-Kyeong;Yong, Jin-Sun
    • Journal of Hospice and Palliative Care
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    • v.12 no.4
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    • pp.220-227
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    • 2009
  • Purpose: The purpose of the study was to investigate how much understand about artificial hydration in patients with terminal cancer, according to the subject groups, including patients, families, and general public. Methods: Data were collected from June 2007 to December 2007 and the participants included 22 hospitalized patients in the hospice unit of S Hospital, 100 families, and 101 participants who participated in a hospice education program for the general public. The questionnaire was developed through literature review, interview with patients' families, and expertise consultation. Data were analyzed using descriptive statistics with an SAS program. Results: Understanding of artificial hydration among patients, families and general public was examined from three perspectives. From an ethical perspective, 'if you receive artificial hydration, you can live longer', 45.5%, 63%, and 52.4% of the above three groups, respectively, answered "yes". From an emotional perspective, 'artificial hydration must be provided', 81.8%, 70% and 58.4%, respectively, agreed. From a cultural perspective, 'if artificial hydration is not provided for the patient, the families will feel painful', 95.5%, 83%, and 88.2%, respectively, answered "yes". Conclusion: This study found the differences in understanding of artificial hydration among patients, families and general public, and also found that less than 50 percent of the participants understood artificial hydration appropriately. We suggest, therefore, that patients' understanding about artificial hydration should be determined in the clinical setting and then followed by individualized education according to given medical situations.

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Relationship between Job Stress contents, Depression in dental hygienists in D City (D도시에 종사하는 일부 치과위생사의 직무스트레스 및 우울과의 관련성)

  • Han, Se-Young
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.10 no.11
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    • pp.3487-3493
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    • 2009
  • The degree of depression of dental hygienist was analyzed to reveal the various factors related to them. The self-administered between June 1st, and 30st, 2009, questionnaires were filled out from 221 dental hygienist in D City. 1.The distribution for depression degree has shown the rate as 79.1% in normal range group, 15.4% in mild depression group, 4.1% in moderate depression group and 1.4% in severe depression group, 2.As for depression, junior college, lower salary, poor sense satisfaction in work, not fit to the job, low personal relation with peer works or supervisors, poor subjective condition of health, without regular eating habits, without alcohol drinking, without regular exercise, in the group with higher level of job demand, lower job autonomy and lower supervisor support than their respective counterparts. 3.Concerning correlation between depression and various factors, while level of depression correlated with was negatively sense satisfaction, fit to the job, personal relation with peer works or supervisors, subjective condition of health, spervisor support, coworker support, it was positively correlated with job demand. Resulting from these results, in order to resolve depression properly, implementation and maintenance of program should be renewed to improve various kinds of factors.

Clinical Observation of Bell's Palsy (침치료(鍼治療)에 의한 말초성(末梢性) 안면신경마비(顔面神經麻痺)의 임상적(臨床的) 관찰(觀察))

  • Kang, Sung-Keel;Kim, Yong-Suk
    • The Journal of Korean Medicine
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    • v.16 no.2 s.30
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    • pp.9-16
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    • 1995
  • Forty four patients with Bell's palsy were treated with acupuncture from onset and clinical observation was carried on from March 1994 through Feburary 1995. Acupuncture treatment was done 3 times per week and the acupuncture points were LI4 Hapkok, ST36 Choksamni, LI20 Yonghyang, BL2 Ch'anjuk, TE17 Yep'ung, ST4 Chich'ang, ST6 Hyopko, GV26 Sugu, CV24 Sungjang, GB14 Yangbaek and Ex-HN4 Oyo. They were inserted to a depth of 0.5 to 1.0 cm. After insertion, manipulation was carried on until the patients felt strong numbness or De Qi sensation induced by rotating or twisting needles. Through-needling in lengths varying from 2.0 to 3.5 cm was also applied from ST4 Chich'ang to ST6 Hyopko, from GV26 Sugu or CV24 Sungjang to ST4 Chich'ang and from GB14 Yangbaek to Ex-HN4 Oyo. The mean age was 39.3 and 63.6% of the patients were women, including one pregnant woman. There was no recurrent palsy in this study. By applying the House-Brackmann facial nerve grading scales, patients were evaluated weekly from the first treatment to judged recovery or the 7th week of the treatment. 86.4% of the patients were recovered completely within 7 weeks and the average healing period was 3.7 weeks.

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A Clinical Study on the Association between Sasangin and Serum Leptin Level (사상인과 혈청 렙틴 농도의 연관성에 관한 임상연구)

  • Lee, Si-Woo;Kim, Sul-Gi;Baek, Yeong-Hwa;Yoo, Jong-Hyang;Kim, Yun-Jeong;Lee, Su-Kyung
    • Journal of Sasang Constitutional Medicine
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    • v.22 no.1
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    • pp.34-40
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    • 2010
  • 1. Objectives: Leptin is ob-gene originated hormone that is concerned with energy metabolism, obesity and asthma which features are supposed to related with Sasangin's 4 viscera physiological theory of Sasang constitutional medicine(SCM). This study aims to investigate whether serum leptin concentration is associated with Sasangin. 2. Methods: Two Way ANOVA analysis was used on the constitution and serum leptin concentration corresponding with BMI among 1054 cases drawn from the Constitutional Information Bank, which was a database with clinically confirmed constitution cases collected from 21 oriental medical institutes in Korea starting from November 2007 to May 2009. The measurement of serum leptin concentration is implemented through radioimmunoassay by request to SCL. 3. Results: Male subjects showed notable difference(p=0.033) in the comparison between constitution and serum leptin concentration corresponding to BMI levels. Tae-eumins showed the highest serum leptin concentration levels in the normal and overweight groups, followed by Soyangin and Soeumin. As the groups changed from overweight to obese, there was an interaction phenomenon in the order of serum leptin concentration levels(p=0.040). As a result, Soeumins showed the highest serum leptin concentration levels and Tae-eumins and Soyangins followed in place. Female subjects did not show statistically notable differences in comparison between constitution and serum leptin concentration corresponding to BMI levels(p=0.239). Serum leptin concentration levels among overweight and obese groups, resulted in the order of Soeumins, Tae-eumins, and Soyangins. But in the as groups changed from overweight to normal the order resulted in Tae-eumin, Soyangin, and Soeumin(p=0.660). 4. Conclusion: Due to a number of limitations in this study, the examination of the relation between constitution and leptin, a main hormone responsible for the digestion, appetite, and energy metabolism, resulted to be uncertain. But statistically notable differences were confirmed in male Tae-eumins with the consideration of BMI. Further examination of the relation between constitution and leptin is necessary through prospective studies with the restriction of confusion variables in the future.

Anti-wrinkle Effect of Morinda citrifolia (Noni) Extracts (노니 추출물의 주름개선 효과연구)

  • Lee, Jung-Noh;Kim, Sang-Woo;Yoo, Young-Kyoung;Lee, Ghang-Tai;Lee, Kun-Kook
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.32 no.4 s.59
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    • pp.227-231
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    • 2006
  • Wrinkle formation is mainly attributed to the environmental factors such as UV rays, air pollution, smoking and stress etc. Especially, UV rays induce premature skin aging which is characterized by deep wrinkle, leathery dryness etc. Recently, researches on the wrinkle formation and its prevention have been the main theme in cosmetics fields. We have studied the various plant extracts having anti-wrinkle effects and finally showed that Noni (Morinda citrifolia) extracts have the efficacy of promoting the type I collagen synthesis in normal human fibroblast, using PICP assay. We purified one active compound from Noni extracts and identified its structure. It was identified as 6,7-Dimethoxy-2H-1-Benzopyran-2-one; scopoletin by $^1H-NMR,\;^{13}C-NMR,$ IR, Mass analysis. Scopoletin increased collagen synthesis in a dose dependent manner (89.5% at $0.2{\mu}g/mL$). In order to verify the anti-aging effectiveness of the cream containing 3% noni extracsts, we performed the in vivo test with some female volunteers for 12 weeks. It reduced the signs of aging, especially face wrinkles. From these results, we conclude that the noni extracts could be used as an useful anti-wrinkle agent.

Evaluation of the Model Accuracy according to Three Types of Dental Scanner (세 가지 방식의 스캐너 종류에 따른 모형 정확도 평가)

  • Lee, Jae-Jun;Park, Jin-Young;Bae, So-Yeon;Jeon, Jin-Hun;Kim, Ji-Hwan;Kim, Woong-Chul
    • Journal of dental hygiene science
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    • v.15 no.2
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    • pp.226-231
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    • 2015
  • The purpose of this study was to evaluate the accuracy of model according to three types of dental scanner. A maxillary acrylic model was prepared and duplicated 10 times by silicone impression materials. Corresponding working casts were formed from scannable stone and got a 3-dimensional digital models using three different scanners. The distance of each measurement region was measured using vernier calipers and the respective program. One-way ANOVA and the Tukey honestly significant difference post hoc test (${\alpha}=0.05$) was performed using IBM SPSS Statistics 21.0. Overall, the stone cast is smaller than the digital models in measurement distance. And measuring point value of laser scanner showed the most similar values and measurement points value of digital vernier calipers. Digital model of white light scanner showed similar values in the measurement points value of the blue light scanner. In conclusion, the laser scanner showed the best accuracy among the three types of dental scanner. However, the difference between the digital models and the stone cast can be accommodated in making prostheses. Thereby, three types of dental scanner are available in a clinically acceptable range.

Clinical Result of the Patent Ductus Arteriosus in the Premature Infants (미숙아 동맥관 개존증의 치료성적)

  • 김오곤;이석재;홍종면;홍장수;전용선;김공수;한헌석
    • Journal of Chest Surgery
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    • v.32 no.1
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    • pp.16-21
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    • 1999
  • Background: This study is to suggest the optimal method as a treatment for the patent ductus arteriosus in the premature infants. Material and Method : Between April 1994 and April 1997, 45 premature infants with evidence of a hemodynamically significant patent ductus arteriosus associated with cardiopulmonary compromise underwent indomethacin therapy, surgical treatment, or both. Thirty-nine infants received indomethacin and twelve infants among them were surgically ligated because of indomethacin failure(5) or complications(7). Six infants, who weighed less than 1,500 gm at birth, were referred for primary surgical ligation because of contraindication to indomethacin therapy. Result: The failure rate of indomethacin therapy was 43%(17/39) and the complications(13/39, 33%) to the indomethacin were associated with a high morbidity and mortality. Among the infants who underwent ligation, there were no failures and complications related to the operation. This data suggests that in the premature neonate with a hemodynamically significant PDA, (1) indomethacin therapy is associated with a high failure rate and significant complications, (2) surgical duct closure is associated with minimal morbidity. Conclusion: Although the results of this study cannot suggest the optimal management for PDA in premature infants, primary surgical ligation may be considered. However, long-term studies will be needed to confirm this later.

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