• Title/Summary/Keyword: 임상 결과 예측

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A Novel Method for Automated Honeycomb Segmentation in HRCT Using Pathology-specific Morphological Analysis (병리특이적 형태분석 기법을 이용한 HRCT 영상에서의 새로운 봉와양폐 자동 분할 방법)

  • Kim, Young Jae;Kim, Tae Yun;Lee, Seung Hyun;Kim, Kwang Gi;Kim, Jong Hyo
    • KIPS Transactions on Software and Data Engineering
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    • v.1 no.2
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    • pp.109-114
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    • 2012
  • Honeycombs are dense structures that small cysts, which generally have about 2~10 mm in diameter, are surrounded by the wall of fibrosis. When honeycomb is found in the patients, the incidence of acute exacerbation is generally very high. Thus, the observation and quantitative measurement of honeycomb are considered as a significant marker for clinical diagnosis. In this point of view, we propose an automatic segmentation method using morphological image processing and assessment of the degree of clustering techniques. Firstly, image noises were removed by the Gaussian filtering and then a morphological dilation method was applied to segment lung regions. Secondly, honeycomb cyst candidates were detected through the 8-neighborhood pixel exploration, and then non-cyst regions were removed using the region growing method and wall pattern testing. Lastly, final honeycomb regions were segmented through the extraction of dense regions which are consisted of two or more cysts using cluster analysis. The proposed method applied to 80 High resolution computed tomography (HRCT) images and achieved a sensitivity of 89.4% and PPV (Positive Predictive Value) of 72.2%.

A Performance Comparison of Machine Learning Classification Methods for Soil Creep Susceptibility Assessment (땅밀림 위험지 평가를 위한 기계학습 분류모델 비교)

  • Lee, Jeman;Seo, Jung Il;Lee, Jin-Ho;Im, Sangjun
    • Journal of Korean Society of Forest Science
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    • v.110 no.4
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    • pp.610-621
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    • 2021
  • The soil creep, primarily caused by earthquakes and torrential rainfall events, has widely occurred across the country. The Korea Forest Service attempted to quantify the soil creep susceptible areas using a discriminant value table to prevent or mitigate casualties and/or property damages in advance. With the advent of advanced computer technologies, machine learning-based classification models have been employed for managing mountainous disasters, such as landslides and debris flows. This study aims to quantify the soil creep susceptibility using several classifiers, namely the k-Nearest Neighbor (k-NN), Naive Bayes (NB), Random Forest (RF), and Support Vector Machine (SVM) models. To develop the classification models, we downscaled 292 data from 4,618 field survey data. About 70% of the selected data were used for training, with the remaining 30% used for model testing. The developed models have the classification accuracy of 0.727 for k-NN, 0.750 for NB, 0.807 for RF, and 0.750 for SVM against test datasets representing 30% of the total data. Furthermore, we estimated Cohen's Kappa index as 0.534, 0.580, 0.673, and 0.585, with AUC values of 0.872, 0.912, 0.943, and 0.834, respectively. The machine learning-based classifications for soil creep susceptibility were RF, NB, SVM, and k-NN in that order. Our findings indicate that the machine learning classifiers can provide valuable information in establishing and implementing natural disaster management plans in mountainous areas.

Numerical Study of the Heat Removal Performance for a Passive Containment Cooling System using MARS-KS with a New Empirical Correlation of Steam Condensation (새로운 응축열전달계수 상관식이 적용된 MARS-KS를 활용한 원자로건물 피동냉각계통 열제거 성능의 수치적 연구)

  • Jang, Yeong-Jun;Lee, Yeon-Gun;Kim, Sin;Lim, Sang-Gyu
    • Journal of Energy Engineering
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    • v.27 no.4
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    • pp.27-35
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    • 2018
  • The passive containment cooling system (PCCS) has been designed to remove the released decay heat during the accident by means of the condensation heat transfer phenomenon to guarantee the safety of the nuclear power plant. The heat removal performance of the PCCS is mainly governed by the condensation heat transfer of the steam-air mixture. In this study, the heat removal performance of the PCCS was evaluated by using the MARS-KS code with a new empirical correlation for steam condensation in the presence of a noncondensable gas. A new empirical correlation implemented into the MARS-KS code was developed as a function of parameters that affect the condensation heat transfer coefficient, such as the pressure, the wall subcooling, the noncondensable gas mass fraction and the aspect ratio of the condenser tube. The empirical correlation was applied to the MARS-KS code to replace the default Colburn-Hougen model. The various thermal-hydraulic parameters during the operation of the PCCS follonwing a large-break loss-of-coolant-accident were analyzed. The transient pressure behavior inside the containment from the MARS-KS with the empirical correlation was compared with calculated with the Colburn-Hougen model.

Long-Term Outcome of Reattached Tooth Fragment in Permanent Anterior Teeth of Children and Adolescents (소아 및 청소년의 영구치 치관 파절시 파절편 재부착술의 추적 관찰)

  • Kang, Hoyeon;Chae, Yongkwon;Lee, Koeun;Lee, Hyo-seol;Choi, Sungchul;Nam, Okhyung
    • Journal of the korean academy of Pediatric Dentistry
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    • v.48 no.1
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    • pp.42-49
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    • 2021
  • This study aimed to evaluate the long-term outcomes of teeth treated with reattachment technique in children and adolescents. Twenty seven permanent anterior teeth from 21 patients treated with fragment reattachment were evaluated. Clinical photos and medical records were used to assess treatment outcomes. Effect of pulp treatment and the ratio of fragment on success rate were statistically analyzed. Detachment of fragment was observed in 17 teeth, and their duration of retention was 21.41 ± 23.39 months. Repeated trauma was found to be the most frequent causes of failure. Pulp treatment before reattachment did not affect the success rate (p > 0.05). The mean ratio of fragment was 0.482 ± 0.147, and the success rate was affected by the ratio of fragment (p = 0.018). The median retention time of the teeth was 72 months if the ratio was under 0.5, and 8 months for that of the others. A significant correlation was found between the ratio of fragment and retention time (p = 0.003). Reattachment can be a predictable treatment option for crown fracture in anterior teeth in children and adolescents when a fracture involves less than 50% of the clinical crown.

Study of the Derive of Core Habitats for Kirengeshoma koreana Nakai Using HSI and MaxEnt (HSI와 MaxEnt를 통한 나도승마 핵심서식지 발굴 연구)

  • Sun-Ryoung Kim;Rae-Ha Jang;Jae-Hwa Tho;Min-Han Kim;Seung-Woon Choi;Young-Jun Yoon
    • Korean Journal of Environment and Ecology
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    • v.37 no.6
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    • pp.450-463
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    • 2023
  • The objective of this study is to derive the core habitat of the Kirengeshoma koreana Nakai utilizing Habitat Suitability Index (HSI) and Maximum Entropy (MaxEnt) models. Expert-based models have been criticized for their subjective criteria, while statistical models face difficulties in on-site validation and integration of expert opinions. To address these limitations, both models were employed, and their outcomes were overlaid to derive the core habitat. Five variables were identified through a comprehensive literature review and spatial analysis based on appearance coordinates. The environmental variables encompass vegetation zone, forest type, crown density, annual precipitation, and effective soil depth. Through surveys involving six experts, importance rankings and SI (Suitability Index) scores were established for each variable, subsequently facilitating the creation of an HSI map. Using the same variables, the MaxEnt model was also executed, resulting in a corresponding map, which was merged to construct the definitive core habitat map. Out of 16 observed locations of K. koreana, 15 were situated within the identified core habitat. Furthermore, an area historically known to host K. koreana but not verified in the present, Mt. Yeongchwi, was found to lack a core habitat. These findings suggest that the developed models exhibit a high degree of accuracy and effectively reflect the current ecological landscape.

The Effects of Medical Students' Self-Directed Learning Ability, Self-regulated Learning, and Communication Ability on Self-Efficacy in Performing Medical Treatment (의과대학생의 자기주도학습능력, 자기조절학습, 의사소통능력이 진료수행 자기효능감에 미치는 영향)

  • Nam Joo Je;Ji-Won Yoon;Jeong Seok Hwa
    • The Journal of the Convergence on Culture Technology
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    • v.10 no.3
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    • pp.267-278
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    • 2024
  • This study was a descriptive research study targeting medical students to determine the impact of self-directed learning ability, self-regulated learning, and communication ability on self-efficacy in performing medical treatment. This study randomly selected medical students from Region J, located in Province G, as the approximate population, and a total of 125 copies were finally analyzed. Descriptive statistics were analyzed using t-test, ANOVA, correlation, and multiple regression analysis using IBM SPSS/25. Self-efficacy in performing medical treatment was related to self-directed learning ability (r=.61, p<.001), self-regulated learning (r=.50, p<.001), and communication ability (r=.33, p<.001). There was a positive correlation with all of them. As a result of analyzing the variables that affect the subject's self-efficacy in performing medical treatment using hierarchical multiple regression, self-directed learning ability was found to be the factor that best predicts self-efficacy in performing medical treatment, followed by self-regulated learning and communication ability. The total explanatory power was 46.6%. Acquiring specialized knowledge and becoming a doctor after graduation through clinical practice and acquiring the basic clinical practice skills necessary to successfully perform one's duties are important tasks that medical students must accomplish. Therefore, in order to improve medical students' self-efficacy in performing medical treatment, the importance of improving health care, major satisfaction, and life satisfaction must be recognized and managed. In addition, efforts to develop programs and improve systematic systems that can improve self-directed learning, self-regulated learning, and communication skills should also be supported.

3DentAI: U-Nets for 3D Oral Structure Reconstruction from Panoramic X-rays (3DentAI: 파노라마 X-ray로부터 3차원 구강구조 복원을 위한 U-Nets)

  • Anusree P.Sunilkumar;Seong Yong Moon;Wonsang You
    • The Transactions of the Korea Information Processing Society
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    • v.13 no.7
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    • pp.326-334
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    • 2024
  • Extra-oral imaging techniques such as Panoramic X-rays (PXs) and Cone Beam Computed Tomography (CBCT) are the most preferred imaging modalities in dental clinics owing to its patient convenience during imaging as well as their ability to visualize entire teeth information. PXs are preferred for routine clinical treatments and CBCTs for complex surgeries and implant treatments. However, PXs are limited by the lack of third dimensional spatial information whereas CBCTs inflict high radiation exposure to patient. When a PX is already available, it is beneficial to reconstruct the 3D oral structure from the PX to avoid further expenses and radiation dose. In this paper, we propose 3DentAI - an U-Net based deep learning framework for 3D reconstruction of oral structure from a PX image. Our framework consists of three module - a reconstruction module based on attention U-Net for estimating depth from a PX image, a realignment module for aligning the predicted flattened volume to the shape of jaw using a predefined focal trough and ray data, and lastly a refinement module based on 3D U-Net for interpolating the missing information to obtain a smooth representation of oral cavity. Synthetic PXs obtained from CBCT by ray tracing and rendering were used to train the networks without the need of paired PX and CBCT datasets. Our method, trained and tested on a diverse datasets of 600 patients, achieved superior performance to GAN-based models even with low computational complexity.

A Survey on the Perception of Food Sanitation Officers Toward the Genetically Modified Foods (유전자재조합식품에 대한 관련 식품위생공무원의 인지도 조사)

  • Oh Kyeung Nam;Lee Soon Ho;Lee Woo Young;Park Hye Kyung;Park Sun Hee
    • Journal of Food Hygiene and Safety
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    • v.20 no.1
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    • pp.22-35
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    • 2005
  • A survey was conducted to investigate the perception of food sanitation officers toward the Genetically Modified Foods. They were mainly from Regional Agencies of KFDA, City/Province office, and National quarantine station. Some of them were professors of university and researchers of research institute. Most of respondents had experiences of hearing or reading GM foods (over $95\%$) and over $90\%$ of respondents much needed the label of GM foods. Although some of officers of city/province office and national quarantine station showed less knowledge than other respondent groups, most of respondents had basic knowledge about biology. The frequency of respondents worked over 20 years and worked in the general administration was higher than that of other groups in the question of unsafe of GM foods. The answer frequency of careless treatment of foods was highest in the question of risk factor, and the frequency of GM foods was lowest ($4.4\%$). It was concluded that food sanitation officers had positive opinion about GM foods, but there were some differences in the knowledge among agencies. Therefore, it is necessary more educations and informations are needed for food sanitation officers.

Clinical Characteristics in Patients with Kawasaki Disease Who Received Intravenous Gamma-globulin Retreatment (가와사끼병에서 감마글로불린 재투여가 필요했던 경우의 임상적 특징)

  • Kim, Deok-Soo;Hahn, Yoon-Soo;Han, Heon-Seok
    • Clinical and Experimental Pediatrics
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    • v.45 no.11
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    • pp.1411-1416
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    • 2002
  • Purpose : Although the use of intravenous gamma-globulin(IVGG) in Kawasaki disease(KD) is effective in reducing clinical symptoms and coronary artery complications, 20-30% of patients have persistent or recrudescent fever and ongoing clinical symptoms. In these patients, the additional infusion of IVGG is considered. The authors studied the characteristics of patients who received IVGG retreatment, and compared them with the patients who did not need IVGG retreatment, for determination of IVGG retreatment. Methods : We reviewed the medical records of 117 KD patients who could be followed up at least six months. We studied the conventional laboratory findings, electrocardiogram(EKG), signal averaged ECG(SAECG) and echocardiogram. Results : Twenty three patients had early cardiac complications during the six months of follow-up. Four patients had late cardiac complications after six months. The early cardiac complication rate was higher in the IVGG retreatment group than the single infusion group(P<0.0001). The late complication rate was also higher in the retreatment group(P<0.0001). The patients who received methyl-prednisolone(m-PD) pulse therapy had much higher rates of early and late cardiac complications than those who received a single IVGG infusion. Among the clinical data and laboratory findings, only CRP increased significantly in patients who have had the cardiac complications. The IVGG retreatment group had increased CRP than the single infusion group. Conclusion : The patients with increased initial CRP may have an increased incidence of complications and an increased possibility of IVGG retreatment. We thought that retreated KD patients might have inflammations severe enough to need high dose IVGG as shown by high CRP levels, and IVGG retreatment could not prevent coronary artery lesions sufficiently.

Possibility of Clinical Philosophical Interpretation of Juyeok through Synchronicity (동시성을 통한 『주역』의 임상철학적 해석가능성)

  • Seok, Young-Jin
    • Journal of Korean Philosophical Society
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    • v.131
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    • pp.223-244
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    • 2014
  • In this paper, the author interprets Juyeok (The Book of Changes) as a philosophical book on self-culture instead of a book on divination. Juyeok, originally, was a book on divination written to tell fortunes; however, it has been a rich source producing the discourse of the humanities. This is because it has a unique system of linguistic symbols. Gwae-Hyo (Hexagrams and Horizontal Lines) system of Juyeok has a number of symbolic features, and there is too much room for new philosophical, cultural interpretations. Thus, Juyeok can be applied to any information and events, and it can, accordingly, help solve the problems of life we are facing. Moreover, Juyeok's unique characteristics are revealed very well in active intervention of persons who read and interpret it. Carl Gustav Jung is the very person who argued that one should interpret Juyeok through this active intervention. In the foreword of Juyeok translated by Richard Wilhelm, he mentions a possibility of the interpretation of Juyeok applying 'synchronicity.' According to him, Juyeok is a material not to predict the future or tell the fate ordained, but to look back on oneself or find the solutions of problems oneself. It allows the inquirer to interpret Gwae-Hyo-Sa (Explanations) not simply through the result of fortune-telling but the act of telling one's fortune. He applies 'synchronicity' to the finding of answers to one's problems in the given Gwae-Hyo-Sa. Synchronicity refers to 'the principle of non-causal relationship explaining a phenomenon of meaningful coincidence.' Here, simultaneity, unlike contingency the principle of causality refers to, means 'meaningful coincidence.' He presents a theory that the divination signs derived from Gwae-Hyo-Sang (Images) through synchronicity is a reflection of the psychology of the unconscious the fortune-teller or a man who receives the results of the divination signs has under certain circumstances on the outside. This is because Jung interprets it like this because the way of communication of Juyeok using symbolic language is not direct but indirect. Juyeok's system of symbolic language aims not at delivering objective knowledge, but the reader's self-transformation. This point can be applied in clinical philosophy. People who suffer from agony and pain in their daily lives may find meaningful and helpful advice for themselves no matter what Gwae-Hyo-Sa they choose in Juyeok. This is because it was originally hidden in their inner space and just revealed concretely through Gwae-Hyo-Sang or Gwae-Hyo-Sa in Juyeok. In this sense, we connect the meaning Gwae-Hyo-Sang or Sa contains from Juyeok to their circumstances, read counsel or advice needed ourselves and make it our own to be able to have power to change and help ourselves. And at this very point may be evaluated as an important role of Juyeok.