• ICROS
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• v.21 no.2
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• pp.39-46
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• 2015

근래에 들어서 노인인구과 장애인구의 지속적인 증가로 인해 재활용 로봇 산업이 지속적인 관심을 받고 있다. 특히 재활 로봇은 환자의 삶의 질 향상과 밀접한 관계가 있고, 인간의 기능을 보조하는 시스템기술로 로봇공학과 밀접한 관계가 있는 분야이므로 더욱 주목받고 있다. 본 논문에서는 현재 활발히 연구가 진행되고 있는 다양한 재활 로봇의 기술 분류와 공개된 시스템의 개발현황을 소개하며 시스템들의 특징을 간략하게 소개하였다. 재활 로봇은 치료 목적 운동에 따라 다양한 형태로 개발될 수 있으며, 실제 상용화된 제품들이 있지만 임상적 효능과 실제 사용성 평가와 관련한 연구가 부족한 실정이다. 실사용자 및 의료계와의 지속적인 협력으로 지속적인 기술 개발의 필요성이 요구될 것으로 전망된다.

• Journal of Genetic Medicine
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• v.7 no.1
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• pp.37-44
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• 2010

Purpose : Kabuki syndrome is a multiple congenital malformation syndrome with mental retardation. It was named after its characteristic appearance, a face resembling that of an actor in a Kabuki play. To date, six Korean cases of Kabuki syndrome have ever been reported. Here, we present the phenotypic and genetic characteristics of six patients with Kabuki syndrome. Materials and Methods : Between 2003 and 2009, six Korean girls have been diagnosed and followed up as Kabuki syndrome at Center for Genetic Diseases of Ajou University Hospital. Their clinical and laboratory data were collected and analyzed by the retrospective review of medical records. Results : All six patients showed the characteristic facial dysmorphism and developmental delay. Persistent fingertip pads were also found in all patients. Most patients showed postnatal growth retardation (83.3%) and hypotonia (83.3%). Opthalmologic problems were common, particularly for strabismus (83.3%). Congenital heart defects were present in three patients (50%). Skeletal abnormalities including 5th finger shortening (83.3%), clinodactyly (50%), joint hypermobility (50%) and hip dislocation (16.7%) were also observed. There was no patient who had positive family history for Kabuki syndrome. Cytogenetic and molecular cytogenetic analyses including karyotyping and array CGH could not reveal any underlying genetic cause of Kabuki syndrome. Conclusion : Korean patients with Kabuki syndrome showed a broad spectrum of clinical features affecting multiple organ systems. Although clinical manifestations of Kabuki syndrome have been well established, our results failed to detect recurrent chromosome aberrations which could cause Kabuki syndrome. Its natural history and genetic background remains to be further studied for providing appropriate management and genetic counseling.

• Anxiety and mood
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• v.13 no.1
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• pp.10-16
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• 2017

Objective : This study aimed to investigate differences in demographic, clinical characteristics, and quality of life between panic-disorder patients with generalized anxiety disorder (PD+GAD) and without generalized anxiety disorder (PD-GAD). Methods : We examined data from 218 patients diagnosed with PD+GAD (150 patients) and PD-GAD (68patients). The following instruments were applied: Stress coping strategies, Beck Depression Inventory (BDI), Beck Anxiety Inventory (BAI), Panic Disorder Severity Scale (PDSS), Anxiety Sensitivity Index-Revised (ASI-R), Albany Panic and Phobia Questionnaire (APPQ), NEO-neuroticism(NEO-N), Short Form health survey-36 (SF-36). Results : Compared to the PD-GAD group, the PD+GAD group had higher scores in emotion-focused coping strategies and clinical severity, such as BDI, BAI, PDSS, ASI, APPQ, and neuroticism. The PD+ GAD group showed lower scores in most scales in SF-36 status than PD-GAD group. Conclusions : This study shows that PD+GAD patients are different from PD-GAD patients in coping strategies, clinical severity and quality of life. It emphasizes the need of personalized therapy in clinical approach among patients with PD+GAD.

• Journal of Sasang Constitutional Medicine
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• v.11 no.2
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• pp.195-207
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• 1999

1. PURPOSE This research is a study on constitutional diagnosis through the external appearances, and for finding shape differences of the hand and foot according to the Sasang Constitution. 2. Method We collected 148 person who were healthy and measured length, breadth, circumference and thickness of their hands and feet with 'The Measurement of R. Martin'. We analyzed shape differences of hand and foot according to the Sasang Constitution and made a certain conclusion. 3. Results and Conclusions We got the morphologic characteristics of hand and foot according to the Sasang Constitution. (1) The physical characteristics. The weight is heaviest in Taeumin. (2) The morphologic characteristics of Hand. (1) The wrist circumference is longest in Taeumin. (2) The finger length / hand length(ratio) is higher Soeumin than Taeumin. (3) The wrist breadth is largest in Taeumin(only male). (4) The wrist breadth is larger Taeumin than Soeumin(only female). (5) The palm length is longer Taeumin than Soyangin(only male). (6) The maximum hand breadth is larger Taeumin than Soeumi (only male). (7) The 2nd, 3rd and 4th finger length is longer Soeumin than Soyangin(only male). (3) The morphologic characteristics of Foot. (1) The foot thickness is thickest in Taeumin. (2) The foot breadth is largest in Taeumin. (3) The ankle circumference is longest in Taeumin(only male).

• Clinical and Experimental Pediatrics
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• v.49 no.9
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• pp.991-995
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• 2006

PFAPA (periodic fever, aphthous stomatitis, pharyngitis, cervical adenitis) syndrome is one of the causes of periodic fever in pediatrics with unknown etiology. It is characterized by abrupt onset of fever, malaise, aphthous stomatitis, pharyngitis and cervical adenitis without long-term sequelae. Laboratory findings of this sporadic and nonhereditary syndrome are so non-specific that the diagnosis is based on clinical findings. Oral prednisolone is quite effective in controlling the symptoms. We report a case of a 6-year-old girl who was diagnosed as having PFAPA syndrome after 2 years of episodes, by excluding other disease entities with similar clinical features. The patient was treated with oral prednisolone and her symptoms improved dramatically.

• Korean Journal of Psychosomatic Medicine
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• v.25 no.2
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• pp.185-192
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• 2017

Objectives : The aims of present study was to investigate clinical characteristics of male patients with eating disorders. Methods : The present study included 32 male patients with eating disorders and 75 female patients with eating disorders, recruited from an eating disorders specialized clinic in a university hospital, Seoul, Korea. We compared clinical characteristics of eating disorders and comorbid conditions of depression and anxiety between men and women with eating disorders. Correlations between eating disorders psychopathology in men with eating disorders and their weight suppression(WS) were investigated. Results : There was no difference in age at presentation, age of onset, illness duration, and body mass index at presentation between genders. Male patients with eating disorders had higher rates of premorbid overweight or obesity than female patients with eating disorders had. WS in the male patients was associated with the severity of their eating disorders. Conclusions : The present study provides grounds for improved understanding for clinical features of eating disorders in males.

• The korean journal of orthodontics
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• v.36 no.6
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• pp.402-411
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• 2006

Objective: This study was carried out to evaluate the distribution and clinical features of patients with degenerative change of the mandibular condyle. Methods: Six thousand and seventy patients with TMD (temporomandibular cisorder) were selected for this study, who had complete initial clinical records and radiographs. Panorama and TMJ panorama radiographs were used to screen the degenerative change in the condyle, and the patients were divided into DJD (degenerative joint disease) and non-DJD groups. Results: The distribution. and clinical features of the two groups were compared. Out of the total number of patients, 31.7% were in the DJD group, and 68.3% were in the non-DJD group. The portion of females was larger in the DJD group (80.8%) than in the non-DJD group (67.5%), and the DJD group had high prevalence in the second and third decades. Lack of incisal contact, retrusive chin, facial asymmetry, and mouth opening limitation were the chief complaints of the patients who had positive relation to DJD. Conclusion: Patients with an orthodontic treatment history, CO-CR discrepancy and crepitation were at possible risk of having DJD.

• Proceedings of the Korea Inteligent Information System Society Conference
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• 2002.11a
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• pp.258-265
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• 2002

베이지안망은 기존의 방법에 비해 불확실한 상황에서도 지식을 표현하고 결론을 추론하는데 유용한 것으로 알려져 있다. 본 논문에서는 대표적인 베이지안망 분류기들을 제시하고, 동일 임상데이터에 대해 서로 다른 유형별 베이지안망 분류기들을 학습하였다. 베이지안망을 적용할 때 변수의 수가 많아짐에 따라 베이지안망의 구조를 학습하는데 탐색공간이 넓어져 어려움이 있다. 본 연구에서는 이런 탐색공간을 효율적으로 줄이기 위하여 클래스 노드의 Markov blanket에 속한 특징들로 집합을 축소하는 것을 제안하고, 실험을 통해 이 특징 축소방법이 베이지안망 분류기들의 성능을 높여 줄 수 있는지 알아보았다. 분류기들의 성능에서는 축소한 특징집합으로부터 얻은 베이지안망으로 확장한 나이브 베이지안망 분류기가 가장 우수한 정확도를 가짐을 실험을 통해 알 수 있었다.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.29 no.2 s.43
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• pp.1-35
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• 2003

새 천년으로 들어선 2000년도부터 우리나라의 65세 이상 노령인구는 $7.1{\%}$를 차지하게 되어 본격적인 노령화사회 (UN에서 65세 이상인구가 총 인구의 $7{\%}$ 이상일 경우 노령화 사회로 정의)로 진입하였다. 평균수명의 계속적인 증가에 따라 노인 인구는 급격히 늘어날 전망이며, 따라서 노인성 질환의 발생도 늘어나게 되어 가정 또는 사회가 떠 맡아야할 경제적, 정신적 부담은 더욱 증가하게 된다. 건강하고 행복한 인생의 황혼기를 보내는 것은 인간의 권리이며 누구나 바라는 소망이다. 피부의 노화현상은 심장질환, 암 등에 못지 않게 중요하며, 노인의 경제적, 사회적 활동을 심각하게 위축시키고 있다. 피부노화를 예방하고 노인성 피부질환을 치료할 수 있는 방법을 개발함으로써 노인의 경제, 사회활동을 활동적으로 유지시킬 수 있다. 피부노화는 크게 두 종류로 나눌 수 있다. 그 한가지는 내인성노화(intrinsic aging)로서 세월이 흘러감에 따라 피할 수 없는 노화 현상을 말한다. 두번째는 광노화 (photoaging)로서 오랫동안 햇빛에 노출된 얼굴, 손등, 목뒤 등의 피부에서 관찰되는 노화현상을 말하는 것으로 내인성노화 현상과 자외선에 의한 영향이 합쳐진 결과로 발생한다. 광노화 현상은 자외선의 노출을 피하면 예방할 수 있는 피부노화 현상이다. 내인성 노화는 햇빛에 노출되지 않은 피부에서 주로 관찰된다. 임상적 특징은 비교적 경미하며, 잔주름, 피부건조증, 탄력감소 등을 들 수 있다. 그러나 광노화의 임상적 특징은 내인성 노화에 비하여 심하고, 일찍부터 관찰된다. 내인성 노화에 비하여 굵고 깊은 주름이 발생하며, 잔주름도 많이 발생한다. 햇빛에 노출된 피부에 불규칙한 색소침착이 발생하며 일광흑자 (solar lentigo) 등의 색소질환이 증가한다. 피부가 매우 거칠고, 건조해지며, 탄력성이 감소하여 심한경우 피부가 처지게 된다. 피부노화의 대표적인 증상은 주름살이며, 아직까지 그 발생기전에 대하여는 여러 가지 학설이 있으나 정확히 알려져 있지 않다. 피부에 존재하는 교원질, 탄력섬유등 기질단백질의 손상이 피부 주름살의 주 원인으로 알려져 있다. 또한 얼굴에 존재하는 근육의 분포와 움직임, 유전적 소인, 자외선, 흡연, 폐경, 산화적 손상, 열 등 여러 원인이 복합적으로 작용할 것으로 생각된다. 피부주름살의 원인을 밝히고, 원인인자가 피부주름살을 초래하는 분자생물학적 기전을 이해함으로써 주름살을 예방하고 치료할 수 있는 새로운 방법을 개발할 수 있다.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.3 no.1
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• pp.117-128
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• 1992

For many years, a number of critical issues have been raised in relation to classification criteria. prevalence and clinical features as well as the concept of childhood depression itself. In order to achieve a better understanding of the childhood depression, empirical data on the prevalence and clinical features of depression in childhood and adolescence were reviewed and discussed from the developmental perspective. The developmental perspective proposes that maladaptive behaviors are products of the coping process to normal developmental tasks and it is necessary to make out the normative and adaptive developmental process in order to understand maladaptive behaviors. Age associated changes in depression symptomatology were discussed in relation to cognitive and socio-emotional development and directions for future research in childhood depression were suggested.