• Journal of Food Hygiene and Safety
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• v.23 no.3
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• pp.276-283
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• 2008

To provide the research strategy for protection of children's health from hazardous chemical, we reviewed the hazardous chemicals can be exposed through maternity, children's life style and living environment. Recently, diseases related with children's living condition were focused as asthma, atopy, childhood developmental disability, congenital malformations and obesity. Children can be exposed to hazardous chemicals through an ambient air, water, soil, food, toys and other factors such as floor dust. Also children's health was deeply related with a wrong life style and neglectful caring by a lack of knowledge and information of harmful ones at parents and child care center's nursers. According to the previous study, the chemical risk factor of children's health were identified as inorganic arsenic, bisphenol A, 2,4-D, dichlorvos, methylmercury, PCBs, pesticide, phthalates, PFOA/PFOS, vinyl chloride, et al. Domestic studies for identification of causality between children exposure to chemicals and resulted hazardous effects were not implemented. The confirmation of chemical risk factors through simultaneously performing toxicological analysis, human effect study, environmental/human monitoring, and risk assessment is needed for good risk management. And also, inter-agency collaboration and sharing information can support confirming scientific evidence and good decision making.

• Journal of the Korean Society of Food Science and Nutrition
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• v.35 no.6
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• pp.671-676
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• 2006

We investigated the effect of gingerol (Zingiber officinale Roscoe, Zingiberaceae) on Bcl-2 and Bax expression in MDA-MB-231 human breast cell lines. The oleoresin from rhizomes of ginger contains [6]-gingerol (1-[4'-hydroxy-3'-methoxyphenyl]-5-hydroxy-3-decanone). We previously reported that [6]-gingerol inhibits cell proliferation in MDA-MB-231 human breast cancer cell lines. In this study, we examined protein and mRNA expression associated with cell apoptosis in MDA-MB-231 human breast cancer cell lines. We cultured MDA-MB-231 cells in presence of various concentrations 0, 2.5, 5 and $10\;{\mu}M$ of [6]-gingerol. Bcl-2 protein and its mRNA levels were decreased dose-dependently in cells treated with [6]-gingerol, but Bax protein and its mRNA levels were unchanged by [6]-gingerol treatment. Bcl-2/Bax ratio was decreased in a dose dependent manner treated with [6]-gingerol. Caspase-3 activity was significantly increased dose-dependently in cell treated with [6]-gingerol (p<0.05). In conclusion, we have shown that [6]-gingerol induces apoptosis in MDA-MB-231 human breast cancer cell lines.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.10 no.2
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• pp.277-290
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• 1999

A simulation using the finite-difference time-domain method to analyze the electromagnetic interactions between a cellular phone and the human body was conducted, and a synthesis of a bone-equivalent material to make a human head phantom was performed. A test model of the cellular phone was fabricated to measure its reflection coefficient and radiation pattern in the free space. Various effects of the human body on the characteristics of the phone, such as input impedance, reflection coefficient, radiation pattern, and radiation efficiency are analyzed as the distance between the head and the phone antenna varies. When the phone was operated close to the head, the resonant frequency of the antenna decreased by up to 12%. With the output power of 0.6W, as long as the distance was larger than 30mm, the 1-g averaged peak SAR was below the ANSI/IEEE safety guideline, 1.6 W/kg. To synthesize the bone-equivalent material, an epoxy with hardener and a graphite powder were used as basis ingredients, and a small amount of a conducting epoxy was added to control the conductivity of the material. A material having a relative permittivity of 18.04 and a conductivity of 0.347, which are close to those of the bone at 850 MHz, was synthesized.

• Journal of Environmental Impact Assessment
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• v.5 no.1
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• pp.47-60
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• 1996

Nitrate contamination problems from groundwater supplies have been reported throughout many countries in the world, including Korea. Nitrate salts can induce methemoglobinemia and possibly human gastric cancer. To reduce human health risk from nitrate in groundwater supplies, several nitrate risk-management strategies can be developed based on the acceptable level of human health risk, the reasonableness of nitrate-control cost, and the technical feasibility of nitrate-control methods. However, due to a lack of available information, assessing risk, cost and technical feasibility contains elements of uncertainty. In the present paper, a nitrate risk-management methodology using fuzzy sets in combination with a multiobjective decision-making (MODM) technique is developed to assist decision makers in evaluating, with uncertain information, various nitrate risk-management strategies in order to decide a proper strategy.

• Korean Journal of Environmental Biology
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• v.33 no.4
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• pp.361-374
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• 2015

Endocirne disruptors (EDs) can cause fertility decrease, developmental disorder, and even cancer in animals. Until 90's, EDs were used in various synthetic products including paints, coatings, detergents, plastics, and plasticizers. Currently, in several countries, the production, trade and use of EDs or EDs-suspected chemicals have been regulated while activity to screen the alternatives for EDs including bisphenol-A, phthalate and nonylphenol is active. Although various toxicity test method was developed and applied for screening of alternatives, however, the safety of alternatives has been not fully demonstrated. Some alternatives have high structural similarity with existing EDs, raising the possible risk of endocrine disruption by alternatives. In an effort to develop the safe alternatives, we reviewed the effects of EDs such as bisphenol-A, phthalates, nonylphenol and their substituents. In addition, in-silico analysis for endocrine disrupting activities of some alternatives was presented.

• Proceedings of the KIEE Conference
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• 2009.07a
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• pp.2124_2125
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• 2009

본 논문은 COS 활선 교체 작업시 발생할 수 있는 전기적인 위험성에 대한 연구를 수행한 것으로 현장특성을 최대한 고려하여 시험하였다. 시험결과, 일반적으로 절연체로 생각되는 COS 애관 및 결합애자에서도 전위가 유도됨을 확인하였으며, 활선작업 시 발생할 수 있는 감전에 대한 경로분석 및 인체에 대한 영향을 검토하였다.

• Proceedings of the Korea Air Pollution Research Association Conference
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• 2000.04a
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• pp.80-81
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• 2000

인위적인 에어로졸의 배출은 현대 산업발전과 급속한 도시화로 인해 가중되었으며, 인체 위해성이 높을 뿐만 아니라, 도시지역의 시정감쇄에도 크게 기여한다. 우리 나라에서 시정(visibility)에 대한 연구가 시작된 것은 지난 1980년 후반이었으며, 최근에 이르러 광학적인 연구가 함께 병행됨으로써 보다 과학적이며 체계적인 연구 성과를 얻고 있다. 시정감쇄 현상은 대기오염을 가시적으로 확인할 수 있는 지표중 하나로서 대기질의 광화학적 및 기상학적 변화에 따라 크게 영향을 받는다. (중략)

• Proceedings of the Korea Air Pollution Research Association Conference
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• 2000.11a
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• pp.382-383
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• 2000

산업이 발달함에 따라 휘발성 유기 화합물(VOC : Volatile Organic Compound)의 배출이 급증하고 있다. 이러한 VOC들은 대기중에서 산화물과 공존시 태양광의 작용을 받아 광화학반응을 일으켜 오존등의 광화학 산화성 물질을 생성시켜 광화학 스모그를 유발시키고 일부 VOC는 그 자체로서도 암을 유발시키는등 인체에 좋지 않은 영향을 미치게 된다. 이러한 VOC중 상당수는 대기중에 미량만 존재하게 되더라도 악취를 유발시켜 불쾌감을 주게된다. (중략)

• Proceedings of the Korea Air Pollution Research Association Conference
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• 2000.11a
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• pp.411-412
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• 2000

산업의 발달과 더불어 각종 화학물질들이 여러 산업공정에서 다양한 용도로 이용되고 있다. 인체에 유해한 독성 무기ㆍ유기화합물의 유출 사고나 부적절한 매립 등에 의해 이들 물질이 환경오염을 야기하는 것으로 보고되고 있다. 휘발성 유기화학물의 처리는 물리ㆍ화학적 방법이나 생물학적 방법으로 제거할 수 있다. 생물여과 공정은 오염된 가스를 반응기에 유입하여 고정된 충진물에 형성된 적절한 미생물 층을 이용하여 오염물질을 제거하는 것이다(Deshusses et al., 1995). (중략)

• Proceedings of the Korea Air Pollution Research Association Conference
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• 2000.11a
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• pp.306-307
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• 2000

대기오염에 관한 연구가 진행되면서 광화학반응의 기여도가 높고, 인체에 직,간접으로 영향을 미치는 VOC를 포함한 비기준성 대기오염물질을 실시간으로 측정 할 수 있는 방법에 대한 필요성이 크게 증대하고 있다. Open-path 광학기기는 가스크로마토그래피 등 종래 sampling 방법과는 달리, 대상지역내 대기오염물질을 별도의 채취없이 실시간으로 측정함으로써, 대기오염물질 채취에서 야기되는 오차를 제거하고 여러화학종의 동적 변화에 관한 자료를 제공함으로써 대기오염물질 거동에 중요한 자료를 제공하고 있다. (중략)