• Title/Summary/Keyword: 인체흡수율

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Effective of Body Temperature Increasing during Brain MRI scan (MRI 검사 시 체온상승 효과: 1.5 T vs 3.0 T)

  • Kim, Myeong Seong;Lee, Jongwoong;Jung, Jaeeun
    • Journal of the Korean Society of Radiology
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    • v.11 no.1
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    • pp.49-54
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    • 2017
  • As the Radiofrequency(RF) increases with the magnetic field strength, the wavelength of the RF excitation field becomes smaller, which leads to more the thermal effect in the human-body placed in the electric field. MRI scanner used was GE signa 1.5T, HDx 3.0T and Philips 3.0T with same routine clinical sequence protocol. Therefore temperature was measured before and after each scan. Taken the temperatures in the ear with ear infra-red type thermometer(Braun co). 3.0T were temperature increases more than $0.15^{\circ}C$ and GE 3.0T MRI equipment about $0.14^{\circ}C$ higher than the Philips 3.0T MRI(p<0.012). Psychogenic status was investigated by the survey respondents about their status can not just answer therefore, a little different from the expected. In our study of Thermal effect of clinical MRI with clinical protocol sequence, we found that the 3.0T in the body-temperature rise was greater than the 1.5T. Therefore, in clinical 3.0T examine the dangerous situation caused by the temperature rise occurred (burns, impaired thermoregulatory mechanism in patients with high-temperature damage, exhaustion occurs due to excessive sweating), not to appear the more watched the patient's condition with procedure.

Basic Properties of Stones used for Cooking Utensils and Their Leaching Characteristics for Heavy Metal Elements (조리용구용 석재의 기초 특성과 중금속 원소의 용출 특성)

  • 진호일;김신자;김복란;민경원
    • Economic and Environmental Geology
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    • v.35 no.4
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    • pp.347-353
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    • 2002
  • Dominant rock types of stones used presently for cooking utensils in Korea are pyroxenite, breccia and biotite diorite. Pyroxenite and biotite diorite relatively abundant in mafic minerals have higher specific gravities of 3.0 than breccia of 2.5. Breccia shows the highest absorption (2.9%) among three stones used as cooking utensils and pH value of three stone types shows the alkaline range of 9.7 to 9.9. Among the studied stones used for cooking utensils, biotite diorite is the most durable against abrasion and has the highest strength and therefore, it is expected to be used effectively for the longest time except for other specific causes. Heavy metals such as Cu, Pb, Co, Cr and Ni were leached lower than their detection limit (0.1 ppm) regardless of reaction time and initial pH value of solution. But the leached contents of Fe are various with rock types and leaching conditions and those by acidic solution are generally 1.8 to 31 times higher than those by neutral solution. Breccia and biotite diorite show the highest leached content of Fe in cases of neutral and acidic solutions, respectively. Standard criteria of leached heavy metals and macrominerals should be studied thoroughly to utilize stones for cooking utensils of high quality which are harmless to the human body. Also it is required to examine mon detailed abiochemical properties of various stone types used for cooking utensils.

Design of Broadband PIFA for PCS and IMT-2000 (PCS 및 IMT-2000용 광대역 PIFA 설계)

  • Lee, Jae-Hyang;Kim, Nam;Park, Ju-Derk
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.15 no.3
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    • pp.242-250
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    • 2004
  • In this thesis, a new broadband PIFA(Planar Inverted-F Antenna) for PCS and IMP-2000 applications is designed. The dual-L antenna structure is adopted in order to improve the characteristics of PIFA which usually has a narrow band. The height of the antenna is fixed 6 mm considering terminal's thickness and the structure is deformed into the folded radiation patches to minimize the size of the antenna. The bandwidth of a realized antenna is 1.66∼2.35 ㎓(34.5 %) fur return loss below -10 ㏈ which contain the required bandwidth of PCS and IMT-2000. And Monopole antenna with λ/4 length is designed and compared with dual-L with folded patch in SAR. 1 g and 10 g averaged peak SAR of PIFA are about 25.7 %, 30.3 % lower than those of monopole antenna respectively.

Comparison of Substance Change and Antibacterial Activity Before and After Fermentation Using Resource Plants for The Development of Natural Preservatives (천연방부제 개발을 위한 자원식물을 활용한 발효 전·후 물질 변화와 항균활성 비교)

  • Seo A Jung;Youn Ok Jung;Ga Hyeon Song;No Bok Park
    • Journal of Practical Agriculture & Fisheries Research
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    • v.25 no.1
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    • pp.20-35
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    • 2023
  • Chemical preservatives have a good effect on antibacterial activity, but many side effects on the human body have been reported. Recently, the development of natural preservatives that are harmless to the human body and have preservative functions and self-efficacy is active. In addition, in order to increase the absorption rate of natural products by the human body, the method of fermentation using strains is also increasing. Therefore, this study selected varieties that are harmless to the human body and have good antibacterial activity. 1. The yield of origin, thickness and solvent was investigated. Scutellaria baicalensis Georgi was made in China and received a yield of 21.88% from 50% ethyl alcohol extract. Salvia miltiorrhiza Bunge was made in Korea and received a yield of 25.62% from 50% ethyl alcohol extract. Dryopteris crassirhizoma Nakai was made in China and received a yield of 6.50% from 70% ethyl alcohol extract. 2. The solid fermentation with the S. baicalensis and S. miltiorrhiza with B. Subtilis yield gained 24.40%, 39.30%, and D. crassirhizoma obtained 11.10% yield when fermented with L. casei. 3. After the liquid fermentation, a clear zone of 9mm was identified for the S. aureus strain in the S. baicalensis, and the antibacterial activity was not confirmed in S. miltiorrhiza and D. crassirhizoma. 4. When the S. baicalensis was fermented with L. Casei, it showed high antibacterial activity in C. albicans and S. aureus. S. miltiorrhiza showed antibacterial activity in S. aureus when it was solid with S. cerevisiae. When the spectators were solid with L. casei and S. cerevisiae, antibacterial activity was high in E. coli and S. aureus. Overall, the antibacterial activity after fermentation was much higher than when fermented. 5. The change in active ingredients was baicalin 101.57, baicalein 28.26, and wogonin 5.33mg/g in the S. baicalensis that did not ferment solid. When solid fermentation with S. cerevisiae, the content of baicalinin with baicalin 94.31, baicalein 30.41, and wogonin 3.57mg/g was found to have increased. S. miltiorrhiza that was not fermented, salvianolic acid A was 1.82mg/g, and when fermented with S. cerevisiae, it increased to 5.70mg/g. The active ingredients of the spectators were flavaspidic acid AP, flavaspidic acid PB, flavaspidic acid AB, and flavaspidic acid BB.

The Preparation of Magnetic Chitosan Nanoparticles with GABA and Drug Adsorption-Release (GABA를 담지한 자성 키토산 나노입자 제조와 약물의흡수 및 방출 연구)

  • Yoon, Hee-Soo;Kang, Ik-Joong
    • Korean Chemical Engineering Research
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    • v.58 no.4
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    • pp.541-549
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    • 2020
  • The Drug Delivery System (DDS) is defined as a technology for designing existing or new drug formulations and optimizing drug treatment. DDS is designed to efficiently deliver drugs for the care of diseases, minimize the side effects of drug, and maximize drug efficacy. In this study, the optimization of tripolyphosphate (TPP) concentration on the size of Chitosan nanoparticles (CNPs) produced by crosslinking with chitosan was measured. In addition, the characteristics of Fe3O4-CNPs according to the amount of iron oxide (Fe3O4) were measured, and it was confirmed that the higher the amount of Fe3O4, the better the characteristics as a magnetic drug carrier were displayed. Through the ninhydrin reaction, a calibration curve was obtained according to the concentration of γ-aminobutyric acid (GABA) of Y = 0.00373exp(179.729X)-0.0114 (R2 = 0.989) in the low concentration (0.004 to 0.02 wt%) and Y = 21.680X-0.290 (R2 = 0.999) in the high concentration (0.02 to 0.1 wt%). Absorption was constant at about 62.5% above 0.04 g of initial GABA. In addition, the amount of GABA released from GABA-Fe3O4-CNPs over time was measured to confirm that drug release was terminated after about 24 hr. Finally, GABA-Fe3O4-CNPs performed under the optimal conditions were spherical particles of about 150 nm, and it was confirmed that the properties of the particles appear well, indicating that GABA-Fe3O4-CNPs were suitable as drug carriers.

Quality Characteristics of Yackwa made with Yam (Dioscorea batatas Decne) Powder (마 분말을 첨가한 약과의 제조와 품질특성)

  • Lee, Jeong-Ho;Kim, Jong-Sung
    • Culinary science and hospitality research
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    • v.20 no.6
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    • pp.56-68
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    • 2014
  • Yam Yackwa (YP) was made by addition of yam power (15%) into flour. Depending on extension of storage time, lightness and redness of YP were increased. Yellowness of YP was decreasing until 3 days and increased from 9 days of storage. However, the yellowness of Yackwa without Yam powder (Non-YP) was increasing until 3 days and decreased from 6 days of storage. Hardness, gumminess, and chewiness of YP were improved compared to Non-YP. It means that the addition of yam power makes Yackwa soft. Oil absorption of Non-YP was low. Acid value and peroxide value of YP were 1.57 and 19.04, respectively. Moisture contents, crude ash, crude fat, crude protein, and carbohydrate of YP were $2.55{\pm}0.08%$, $0.71{\pm}0.01%$, $6.11{\pm}0.06%$, $15.97{\pm}1.40%$, and $64.66{\pm}0.09%$, respectively.

Design of the Linked Patch Monopole Antenna and Its SAR Analysis along with Antenna Direction (연결된 패치 형태의 모노폴 안테나 설계 및 안테나 탑재 방향에 따른 SAR 분석)

  • Yang, Joo-Hun;Lee, Seungwoo;Kim, Nam
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.23 no.10
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    • pp.1117-1127
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    • 2012
  • In this paper, the monopole antenna for satisfying GSM900/DCS1800/PCS1900/UMTS2100 services is designed. We can get the characteristic of the low frequency bands by connecting the front patch to the back patch of the antenna and get the low frequency resonance band using a front patch slit. The proposed antenna total volume is $40{\times}98{\times}1.6\;mm^3$, and it is designed on the FR-4 substrate having a relative dielectric constant of 4.4. As measurement result after fabrication, showed that the resonant frequency bandwidths are 156 MHz(828~984 MHz), 708 MHz(1.476~2.184 GHz) based on the return loss of 10 dB, and the radiation patterns show as the omnidirectional shapes for the E-field and H-field. For analyzing the human effects, the proposed antenna is mounted on the mobile-phone case. The averaged peak SAR over 1 g and 10 g is simulated and measured when the input power is 0.25 W. We have checked the variation of the SAR values when the antenna is mounted 4 different directions, then checked the direction having a relatively higher SAR. The results also satisfied the limiting SAR values which are 1.6 W/kg and 2.0 W/kg averaged over 1 g and 10 g tissues respectively.

Embodiment of High Impedance Surface of Meta-Material Characteristic Using Symmetrical AMC Structure and Its SAR Analysis (대칭형 인공자기도체 구조를 이용한 메타물질 특성의 고임피던스 표면 구현 및 SAR 특성 분석)

  • Lee, Seungwoo;Lee, Moung-Hee;Rhee, Seung-Yeop;Kim, Nam
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.38B no.9
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    • pp.744-750
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    • 2013
  • In this paper, we proposed new type of an artificial magnetic conductor(AMC) structure, which has a high impedance surface for realizing the meta-material characteristics. The designed AMC structure set a goal of 3.2GHz, and the reflector, which consists of periodically arrayed AMCs is fabricated and measured. The high impedance improves the reflection coefficient, decreases the system size and interference, and increases the antenna performance. The structure has embodied the high impedance by the thickness and relative permitivity of the dielectric substrate and the design configuration without the metallic via hole which connects the AMC to the GND. The bandwidth is 150% broader than the similar AMC structures. Also, the distance between the antenna and the AMC reflector is decreased by ${\lambda}/10$ as working as the metal(PEC) reflectors. The antenna radiation characteristics are 3dB increased at 10mm away from reflector by measurement. The proposed reflector could be inserted in the portable mobile devices, and the antenna's performance has improved by the reflector. The specific absorption rate is dramatically decreased over 94% because the back radiation of the antenna is shielded.

Potential of Fucoidan Extracted from Seaweeds as an Adjuvant for Fish Vaccine (해조류 유래 Fucoidan의 어류용 백신 항원보조제로서의 가능성에 대한 고찰)

  • Min, Eun Young;Kim, Kwang Il;Cho, Mi Young;Jung, Sung-Hee;Han, Hyun-Ja
    • Journal of Marine Life Science
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    • v.4 no.1
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    • pp.1-13
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    • 2019
  • Fucoidan is a physiologically functional ingredient extracted from seaweed brown algae, which is a sulfated polysaccharide containing fucose as a main molecule backbone. Fucoidan has a variety of immune-modulating or -stimulating effects, including promoting antigen uptake and enhancing anti-bacterial, anti-viral and anti-tumor effects. In addition, recent studies have suggested the possibility of use of fucoidan as a vaccine adjuvant in the field of human vaccine. Use of fucoidan as supplementary feeds have already been studied, but the development of fucoidan as an adjuvant of fish vaccine is still premature. However, the intracellular uptake of fucoidan differs depending on the molecular weight of fucoidan, and there is a limit to the study on specific immune response including the production of antibodies to fish caused by an artificial infection of pathogen. Although the safety of fucoidan has been demonstrated in animal cells, there is a need to confirm the safety of fucoidan in fish. Therefore, active research in this field is needed to use fucoidan as a vaccine adjuvant. This study discussed the effects of fucoidan on immune stimulation, humoraland cellular- immunity including humans and animals. The prospect of fucoidan as a vaccine adjuvant in fisheries also reviewed.

Effects of a Blend of Prunus Mume Extract as an Alternative to Antibiotics on Growth Performance, Activity of Digestive Enzymes and Microflora Population in Broiler Chickens (항생제 대체 사료첨가제로서 매실추출 혼합물이 육계의 성장, 소화 효소 활성도 및 장내 미생물 균총에 미치는 영향)

  • Ko, Y.H.;Yang, H.Y.;Kang, S.Y.;Kim, E.S.;Jang, I.S.
    • Journal of Animal Science and Technology
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    • v.49 no.5
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    • pp.611-620
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    • 2007
  • The current study was designed to define whether a blend of prunus mume extract(25%) containing lactic acid(75%) and grape seed extract(10ppm) could affect in vitro antimicrobial activity and growth performance, intestinal microflora, plasma biochemical profiles and digestive enzymes activities in broiler chickens. In paper disc agar diffusion test, we clearly observed antimicrobial activity against E. coli in response to prunus mume extract or a blend of prunus mume extract. For in vivo test, a total of ninety six 3-d-old male broiler chicks were assigned to basal diet(CON), basal diet supplemented with antibiotics (ANTI) and 0.5% a blend of prunus mume extract(PRNUS) until 35 days of age. Throughout the entire experimental period(3-35 days), there were no differences in BW and FCR between the birds fed the basal diet with antibiotics and the diet supplemented with a blend of prunus mume. However, ANTI group showed a significant increase in BW and total gain compared to CON group. The weights of digestive organs such as the pancreas and mucosal tissues were not affected by dietary treatments. There was no difference in plasma levels of glucose, cholesterol, AST and ALT activity. However, triglyceride in plasma increased(P<0.05) in the birds fed the diet supplemented with 0.5% a blend of prunus mume extract compared to those fed antibiotics supplemented diet. The activities of pancreatic trypsin and amylase, and intestinal hydrolase including disaccharidase were not affected by dietary treatment. The colony forming units(CFU) of lactobacillus in the lower ileal-cecum of the birds fed the diet supplemented with a blend of prunus mume extract was significantly(P<0.05) higher than that of birds fed antibiotic supplemented diet without affecting the CFU of E. coli. In conclusion, the birds fed the diet supplemented a blend of prunus mume as an alternative to antibiotics showed a similar growth performance and an significant increase in lactobacillus population compared with the birds fed basal and antibiotics supplemented diets.