• Title/Summary/Keyword: 인체허용한계

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FDTD를 이용한 인체두부 모델내의 SAR 분포 특성 해석

  • 김두현;홍동욱
    • Proceedings of the Korean Institute of Industrial Safety Conference
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    • 2002.11a
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    • pp.271-275
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    • 2002
  • 전파기술의 진보에 따라 일상생활 주변에서 전자파가 인체에 미치는 영향과 안전노출 허용한계에 대한 관심이 커지고 있다. 비 흡수율( Specific Absorption Rate )은 일반적으로 전자파 흡수율로 정의되고 주로 100[KHz]에서 10[㎓] 사이의 주파수 대역에서 전자파가 생체조직에 미치는 영향을 평가할 때 쓰이는 기본한계가 된다.(중략)

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Review of Crash Landing Load Factor (추락착륙 하중배수에 대한 고찰)

  • Bae, Hyo-gil;Kim, Do-Hyung;Park, Jea Sung
    • Journal of Aerospace System Engineering
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    • v.15 no.1
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    • pp.47-55
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    • 2021
  • When an abnormal landing occurs, aircraft structures should be designed to guarantee occupants survivability without preventing egress. To find out fire root causes at crash, lots of fixed aircraft crash tests were conducted. Appropriate crash load factors were established with the comprehension of structural behavior based on dynamic analysis and investigation of human tolerance. Cargo restraint criteria were set up considering passengers safety and operational cost while analyzing past cargo aircraft accident data using a probabilistic approach. Reviewing results of past crash tests, current crash landing load factor was appreciated physically, medically, and economically.

Validation of enzyme immunoassay for the quantitative measurement of human IgG antibodies specific for Haemophilus influenzae Type b capsular polysaccharide (Haemophilus influenzae type b 피막 다당질 특이 인간 IgG 항체의 정량적 측정을 위한 enzyme immunoassay의 타당성 연구)

  • Kim, Kyung Hyo;Lim, Soo Young
    • Clinical and Experimental Pediatrics
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    • v.50 no.2
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    • pp.143-150
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    • 2007
  • Purpose : This study was conducted to validate enzyme immunoassay (EIA) for the quantitative measurement of human IgG antibodies specific for Haemophilus influenzae type b (Hib) capsular polysaccharide. Method : We evaluated specificity, repeatability, intermediate precision, accuracy, lower limit of quantification (LLOQ), and stability to validate standardized EIA for the quantitative measurement of human anti-polyribosylribitol phosphate (PRP) IgG antibodies. Results : The results indicated that this EIA showed specificity to HbO-HA antigen and repeatability and intermediate precision were within acceptance criteria (repeatability: $CV{\leq}15%$, intermediate precision: $CV{\leq}20%$). The EIA-derived results from this laboratory were equivalent to those obtained by the standard radioactive antigen binding assay (RABA) for quantitation of anti-PRP antibodies in the 28 sera. Spiking recovery result was within acceptance criteria ($100{\pm}20%$). The precision and accuracy of samples in LLOQ were from -14.7 to -4.7% in nominal values, which were within acceptance criteria (precision: $CV{\leq}25%$, accuracy: ${\pm}25%$). Freeze-thaw stability and short term temperature stability were within ${\pm}20%$ of acceptance criteria. Conclusions : The EIA which is performed at the Center for Vaccine Evaluation and Study Ewha Medical Research Institute, is an appropriate serologic assay which can be used for quantitation of anti-PRP IgG antibodies in human sera.

Nitrate Risk Management by Multiobjective Decision-making Technique Using Fuzzy Sets (퍼지이론을 사용한 다기준의사결정기법에 의한 질산의 위해성 관리)

  • Lee, Yong-Woon
    • Journal of Environmental Impact Assessment
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    • v.5 no.1
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    • pp.47-60
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    • 1996
  • Nitrate contamination problems from groundwater supplies have been reported throughout many countries in the world, including Korea. Nitrate salts can induce methemoglobinemia and possibly human gastric cancer. To reduce human health risk from nitrate in groundwater supplies, several nitrate risk-management strategies can be developed based on the acceptable level of human health risk, the reasonableness of nitrate-control cost, and the technical feasibility of nitrate-control methods. However, due to a lack of available information, assessing risk, cost and technical feasibility contains elements of uncertainty. In the present paper, a nitrate risk-management methodology using fuzzy sets in combination with a multiobjective decision-making (MODM) technique is developed to assist decision makers in evaluating, with uncertain information, various nitrate risk-management strategies in order to decide a proper strategy.

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The Prediction of Allowable Limit Distance about Human Body by Vibration Regulation (진동 규제기준에 따른 인체의 허용 한계거리 예측)

  • Song, Jeong-Un;Hong, Woong-Ki;Kim, Seung-Kon
    • Journal of Environmental Impact Assessment
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    • v.21 no.2
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    • pp.289-296
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    • 2012
  • The shock vibration such as machine vibration, blasting vibration etc. has effect on nearby structure as well as human body. The purpose of this study is to predict allowable limit distance of vibration about human body. First of all, vibration velocity such as PPV, PVS was measured by shock vibration experiment, and vibration level was calculated by conversion formula of vibration velocity. And then, allowable limit distance was analyzed by converted vibration level. The results are as follows : Firstly, the correlation coefficient of converted vibration level was over R=0.94, and vibration level caused by PVS was usually represented to high curve line. Secondly, the cross point of vibration level between ground and concrete condition was represented to 66.68dB(V), and allowable limit distance was represented to difference over three times when vibration regulation was raised from 65dB(V) to 80dB(V).

Development and Validation of a Simultaneous Analytical Method for 5 Residual Pesticides in Agricultural Products using GC-MS/MS (GC-MS/MS를 이용한 농산물 중 잔류농약 5종 동시시험법 개발 및 검증)

  • Park, Eun-Ji;Kim, Nam Young;Shim, Jae-Han;Lee, Jung Mi;Jung, Yong Hyun;Oh, Jae-Ho
    • Journal of Food Hygiene and Safety
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    • v.36 no.3
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    • pp.228-238
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    • 2021
  • The aim of this research was to develop a rapid and easy multi-residue method for determining dimethipin, omethoate, dimethipin, chlorfenvinphos and azinphos-methyl in agricultural products (hulled rice, potato, soybean, mandarin and green pepper). Samples were prepared using QuEChERS (Quick, Easy, Cheap, Effective, Rugged and Safe) and analyzed using gas chromatography-tandem mass spectrometry (GC-MS/MS). Residual pesticides were extracted with 1% acetic acid in acetonitrile followed by addition of anhydrous magnesium sulfate (MgSO4) and anhydrous sodium acetate. The extracts were cleaned up using MgSO4, primary secondary amine (PSA) and octadecyl (C18). The linearity of the calibration curves, which waas excellent by matrix-matched standards, ranged from 0.005 mg/kg to 0.3 mg/kg and yielded the coefficients of determination (R2) ≥ 0.9934 for all analytes. Average recoveries spiked at three levels (0.01, 0.1, 0.5 mg/kg) and were in the range of 74.2-119.3%, while standard deviation values were less than 14.6%, which is below the Codex guideline (CODEX CAC/GL 40).

Experimental Study on the Effects of Combustion Products on the Human Body and Suggestion of Law Revision (흡음재의 연소 생성물이 인체에 미치는 영향에 대한 실험적 연구 및 법률 개정 제언)

  • Kang, Jung Ki;Choi, Don Mook
    • Fire Science and Engineering
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    • v.33 no.4
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    • pp.28-34
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    • 2019
  • Regardless of the ignition source, the main factors affecting the spread of flames to the human body are combustibles. The sound absorption material, which is the finishing material used in music institutes and karaoke rooms, consists of polyurethane that generates a large amount of toxic gas with a high amount of combustion gases during a fire. Still, the current law does not require the use of impregnated finishing materials for tutoring services with less than 100 users. In this study, the rate of flame diffusion was measured using the MultiRaelite composite gas measuring instrument (target substance VOC, HCHO, SO2, CO2, CO, HCN, and NO2) for the collection of sound-absorbing materials installed in the actual music academy. The results showed that the toxic gas found in this experiment exceeded the allowable concentration of TWA (Time Weighted Average) and STEL (Short Term Exposure Limit). In addition, a comparative combustion test of the general sound absorber and non-combustion sound absorbing materials on the market showed wide differences in ignition and diffusion. Therefore, based on the results of the experiment, private institutes with less than 100 users should be mandated to use non-combustion sound absorbing materials.

Establishment for analytical method of methanol in wet wipes by headspace gas chromatography (가스크로마토그래프-헤드스페이스를 이용한 물휴지 중 메탄올 정량법 확립 연구)

  • Choi, Yongkyu;Baek, Eunji;Min, Chungsik;Lee, Rheeda;Park, Soonyoung;Ahn, Jaehyung;Kim, Sangseop;Hong, Seonghwa;Kim, Younglim
    • Analytical Science and Technology
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    • v.29 no.5
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    • pp.242-247
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    • 2016
  • This research aims to set up and validate methods of analyzing the methanol in wet wipes and verifies the analysis methods that applied to the wet wipes. We used Headspace (HS) Gas Chromatography (GC) - Flame Ionization Detector (FID) to the establish analysis method of methanol in wet wipes and optimized heating temperature, heating time, GC conditions with column. The result indicated that 3 mL of sample in 20 mL headspace vial can be equilibrated efficiently in headspace sampler at 70 ℃ for 10 min and sample was measured by GC with spli injection mode(10:1). The results show that linearity from 1 to 100 ppm was over R2 0.9995, precision was RSD 1.83 % and accuracy(recovery rate) was 105.44 (±1.05 %) on water matrix and wet wipes matrix removed non-woven fabric. Also, monitoring results of total 20 cosmetics on the market, from 0.00017 to 0.00156 % of methanol was detected from wet wipes.

Comparison of Human Health Risk Assessment of Heavy Metal Contamination from Two Abandoned Metal Mines Using Metal Mine-specific Exposure Parameters (국내 폐금속 광산에 특화된 노출인자를 이용한 두 폐금속 광산 중금속 오염에 대한 인체위해성평가 비교)

  • Lim, Tae-Yong;Lee, Sang-Woo;Cho, Hyen Goo;Kim, Soon-Oh
    • Journal of Environmental Impact Assessment
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    • v.25 no.6
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    • pp.414-431
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    • 2016
  • There are numerous closed and abandoned mines in Korea, from which diverse heavy metals (e.g., As, Cd, Cu, Pb, Zn) are released into the surrounding soil, groundwater, surface water, and crops, potentially resulting in detrimental effects on the health of nearby residents. Therefore, we performed human risk assessments of two abandoned metal mines, Yanggok (YG) and Samsanjeil (SJ). The exposure parameters used in this assessment were specific to residents near mines and the included exposure pathways were relevant to areas around metal mines. The computed total excess carcinogenic risks for both areas exceeded the acceptable carcinogenic risk ($1{\times}10^{-6}$), indicating that these areas are likely unsafe due to a carcinogenic hazard. In contrast, the non-carcinogenic risks of the two areas differed among the studied receptors. The hazard indices were higher than the unit risk (=1.0) for male and female adults in YG and male adults in SJ, suggesting that there are non-carcinogenic risks for these groups in the study areas. However, the hazard indices for children in YG and female adults and children in SJ were lower than the unit risk. Consumption of groundwater and crops grown in the area were identified as major exposure pathways for carcinogenic and non-carcinogenic hazards in both areas. Finally, the dominant metals contributing to carcinogenic and non-carcinogenic risks were As and As, Cu, and Pb, respectively. In addition, the carcinogenic and non-carcinogenic risks of YG were evaluated to be 10 and 4 times higher than those of SJ, respectively, resulted from the relatively higher exposure concentration of As in groundwater within SJ area. Because of lacking of several exposure parameters, some of average daily dose (ADD) could not be computed in this study. Furthermore, it is likely that the ADDs of crop-intake pathway included some errors because they were calculated using soil exposure concentrations and bioconcentration factor (BCF) rather than using crop exposure concentrations.

Ultrastructural Changes on the Synovial Membrane of Rat Temporomandibular Joint under Mild Restraint and Cold Stresses (한냉, 중등도의 구속 스트레스시 웅성백서의 측두하악관절 윤활막의 미세구조 변화에 대한 전자현미경적 연구)

  • Ryu, Jung-Kyun;Mun, Kyung-Hwan;Chun, Yang-Hyun;Hong, Jung-Pyo
    • Journal of Oral Medicine and Pain
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    • v.26 no.3
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    • pp.205-214
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    • 2001
  • 오늘날 스트레스라는 단어는 모든 현대인과 방송, 언론매체에서도 매일 거론되어질 정도로그 중요성이 대두되고 있다. 의학계에서도 스트레스를 단순한 심리적 문제로 국한시키지 않고 과도한 스트레스가 지속될 경우 신경계와 내분비계, 면역계의 변화를 초래해 인체의 항상성에 영향을 미쳐 질병을 일으킨다는 것을 인식하고 있으며 이에 대한 연구가 진행되고 있다. 이러한 질병의 발생과정에서 생체의 일부조직이 파괴됨으로써 기능과 형태변화가 초래될 때 apoptosis가 관여하고 있으며 이에 본 저자는 스트레스와 구강악안면영역에서 발생할 수 있는 질병과의 상관관계를 규명하기 위해 이종의 한냉 스트레스와 다소의 굴신을 허용한 중등도의 구속 스트레스를 부여한 후 측두하악관절 활막의 변화를 전자현미경관찰을 통해 밝혀내고자 한다. Sprague-Dawley계 웅성 백서(200-230 g/bw) 33마리를 구속스트레스부여군 (12마리), 한냉스트레스부여군 (12마리) 및 정상군 (3마리)으로 나누고 이들을 각각 구속장치에 구속한 후 1, 3, 5, 7일에 각각 희생시켰으며 측두하악관절 활막의 변화를 전자현미경으로 관찰하였다. 그 결과는 다음과 같다. 1. 중등도의 구속스트레스군에서 사립체는 부분적으로 농축된 소견을 보였으며 수와 크기에 있어 시간이 지남에 따라 점차 감소하는 소견을 보였다. 2. 중등도의 구속스트레스군에서 과립내형질망은 점점 확장되었으며 불규칙한 형태를 나타내었다. 3. 중등도의 구속스트레스군에서 물결모양의 핵막의 이중구조가 7일군에서 관찰되었다. 4. 한냉 스트레스군에서 사립체는 1일, 3일군에서 약간 부푼 형태를 가지고 그 수가 다소 감소되었으나 시간이 지남에 따라 5일, 7일군에서 건강한 모양으로 점차 증가되었다. 5. 한냉 스트레스군에서 과립내형질망은 1일, 3일군에서 불규칙하게 확장된 소견을 보였으나 5일, 7일군에서는 잘 발달된 형태로 핵 주위에서 다수 관찰되었다. 6. 한냉 스트레스군에서 핵은 전 기간에 걸쳐 큰 변화를 보이지 않았다. 이와 같은 결과를 토대로 측두하악관절 활막조직은 한냉 스트레스 및 중등도의 구속 스트레스에 대하여 중등도의 저항성을 가지고 있는 것으로 생각되며 생리적 적응한계를 넘는 과도하고 지속적인 스트레스에 의하여 활막조직이 apoptosis되어 측두하악관절에 병리적 변화를 초래할 가능성이 있다고 사료되어 이후 지속적인 연구가 요구된다.

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