• Title/Summary/Keyword: 인체구조와 기능

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Design of lattice structure for controlling elastic modulus in metal additive manufacturing (금속 적층제조에서의 격자구조 설계변수에 따른 탄성계수 분석)

  • In Yong Moon;Yeonghwan Song
    • Journal of the Korean Crystal Growth and Crystal Technology
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    • v.33 no.6
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    • pp.276-281
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    • 2023
  • With the high design freedom of the additive manufacturing process, there is a growing interest in multi-dimensional lattice structures among researchers, who are studying intricate structural modeling that is challenging to produce using conventional manufacturing processes. In the case of titanium alloy implants for human insertion, a multi-dimensional lattice structure is employed to ensure compatibility with bones, adjusting strength and elastic modulus to levels similar to those of bones. Therefore, securing a database on the mechanical properties based on lattice structure design variables and the development of related simulation techniques are believed to efficiently facilitate the customization of implants. In this study, lattice structures were additively manufactured using Ti-6Al-4V alloy, and the elastic modulus was measured based on design parameters. The results were compared with simulations, and an approach to finite element analysis for accurate prediction of the elastic modulus was proposed.

Development of Standard Syllabuses for 4 Subjects (Structure and Function of Human Body, Pathogenic Microbiology, Pathophysiology, Mechanisms and Effects of Drug) of Bionursing (기초간호자연과학 4개 교과목(인체 구조와 기능, 병원미생물학, 병태생리학, 약물의 기전과 효과) 표준 강의계획서 개발)

  • Lee, Kyung-Sook;Jeong, Jae Sim;Choe, Myoung-Ae;Kim, Joo Hyun;An, Gyeong Ju;Kim, Jin Hak;Shin, Gi Soo;Kim, Yun Kyung;Lee, Yun Mi;Chu, Sang Hui;ChoiKwon, Smi
    • Journal of Korean Biological Nursing Science
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    • v.15 no.1
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    • pp.33-42
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    • 2013
  • Purpose: The purpose of this study was to develop standard syllabuses of 4 subjects (Structure and Function of Human Body, Pathogenic Microbiology, Pathophysiology, Mechanisms and Effects of Drug) of bionursing. Methods: We developed standard syllabuses of 4 subjects through 3 step discussions and analysis. At first each committee for 4 subjects made the syllabus, after then all researchers discussed together. Finally each committee concluded final one. Committee members consisted of professors who teach that subject at nursing college. Results: Standard syllabus for Biological Nursing I-1 or Structure & Function of Human Body I consisted of 3 parts and 9 themes and for Biological Nursing I-2 or Structure & Function of Human Body II was 3 parts and 9 themes. Standard syllabus for Biological Nursing II or Pathogenic Microbiology consisted of 8 themes and Biological Nursing III or Pathophysiology consisted of 2 parts and 19 themes. Standard syllabus for Biological Nursing IV or Mechanisms & Effects of Drug consisted of 2 parts and 13 themes. Conclusion: The standard syllabuses and titles of 4 subjects of bionursing need to be disseminated to all the nursing college by Academy of Korean Biological Nursing Science. Further researches to investigate curriculum for bionursing and to identify the effects of 4 standard syllabuses were recommended.

Effects of Bovine α-Lactalbumin Added with Oleic Acid and Microbial Transglutaminase on Cancer Cell Apoptosis (올레산과 미생물 유래 트랜스글루타미나제를 첨가한 우유 알파-락트알부민의 암세포사멸 효과)

  • Jeong, Ji-Eun;Hong, Youn-Ho
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.41 no.3
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    • pp.310-319
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    • 2012
  • In order to investigate the biological effects of conformational changes in the folding state of bovine ${\alpha}$-lactalbumin (${\alpha}$-La), the protein was prepared and classified as apo form, microbial transglutaminase (MTGase) added form, or bovine ${\alpha}$-La made lethal to tumor cell (BAMLET) form. Apo ${\alpha}$-La form showed weaker cancer cell inhibitory activity (apoptosis) than native ${\alpha}$-La, which suggests that the metal ion-like $Ca^{2+}$ had a positive effect, whereas BAMLET form showed strong cancer cell apoptotic activity. The BAMLET form seemed to be a molten globule structure that increased hydrophobicity. MTGase added to apo ${\alpha}$-La polymer showed similar anti-cancer activity as native ${\alpha}$-La, and it was well hydrolyzed by digestive enzymes. NMR results showed that BAMLET interacted with oleic acid and produced a complex.

A Comparative Study on the Environmental Impacts by Concrete Strength Using End-point LCA methodology (피해산정형 전과정평가 기법을 적용한 콘크리트 압축강도별 환경영향 비교 분석 연구)

  • Kim, Sung-Hee;Tae, Sung-Ho;Chae, Chang-U
    • Journal of the Korea Concrete Institute
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    • v.26 no.4
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    • pp.465-474
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    • 2014
  • This is a comparative study that shows the overall environmental impacts from concrete structures when different compressive strength of concrete applied to structural systems having the same reference flow with different durability. A total of 24 MPa, 40 MPa and 60 MPa cases is analyzed to define the characteristic using end-point perspective LCA methodology including the stages of production, construction, maintenance and disposal. As results, global warming, non-renewable energy and respiratory inorganics problems are the major issues for assessing environmental impacts of concrete products.

Dioxins and Health: Human Exposure Level and Epidemiologic Evidences of Health Effects (다이옥신과 건강: 인체 노출 수준 및 건강영향에 대한 역학적 연구)

  • Jang, Jae-Yeon;Kwon, Ho-Jang
    • Journal of Preventive Medicine and Public Health
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    • v.36 no.4
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    • pp.303-313
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    • 2003
  • General information is summarized, that is necessary to introduce a scientific assessment of the human health and exposure issue concerning dioxin and dioxin-like compound. Scientific literatures were reviewed to assess the background exposures to the dioxin-like compounds for normal residents. Epidemiologic studies were also reviewed to assess malignant and nonmalignant sweets of dioxins. In 1997, the International Agency for Research on Cancer classified 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) as a human carcinogen, primarily based on occupational cohort studies. The US Environmental Protection Agency made the same decision in it's Draft Dioxin Reassessment. Epidemiologic evidences point to a generalized excess of all cancers, without any pronounced excess at specific sites. Reported non-cancer effects included a range of conditions affecting most systems. Among them, chloracne, elevation in gamma glutamyl transferase(GGT), and alterations in reproductive hormones are related to TCDO, Other adverse outcomes, such as lipid concentrations, diabetes, circulatory and heart diseases, immunologic disorders, neurobehavioral effects, and developmental outcomes require further study before their respective relationships to TCDD can be more definitively assessed.

A Search on the Spatial Orientation in Flight (비행시 공간정위 유지에 대한 고찰)

  • Gu, Bon-Sool
    • Journal of the Korean Society for Aviation and Aeronautics
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    • v.2
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    • pp.139-182
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    • 1994
  • 조종사들은 비행시에 일상 생활 환경에서는 경험하지 못하는 여러가지 적대환경에 폭로된다. 이러한 환경에서는 인체의 평형기관은 실제와 일치하지 않는 정보를 제공해 주는 경우가 허다하다. 예를들면, 내이의 미로 전정기관이나 피하압력기관기 등은 항공기의 기동으로 발생하는 중력과 지구의 중력을 구별 하지 못하는 기능의 한계성때문에 계기비행하에서는 대개의 경우 공간정위상실, 즉 비행착각을 유발한다. 이 착각으로 인한 항공기 사고는 통계상에서 상당 부분이 치명사고로 나타나고 있는데, 이러한 사실은 비행착각현상이 비행안전에 극히 위험한 요소가 되고 있다는 것을 실증한다고 할 수 있다. 그러므로 조종사들은 비행시 공간정위 유지를 위한 철저한 대비가 있어야 한다. 공간정위 상실현상이 잘 발생하는 경우는 야간이나 기타 계기비행 환경에서 주위시각이 제약을 받을 때이다. 즉, 계기비행 환경에서의 편대비행시나 고기동시, 그리고 대조물이 모호한 야간의 활주로에서 이착륙할때 등을 들 수 있다. 비행시 공간정위 상실현상을 예방하기 위해서는 첫째로 이러한 유형의 사고분석자료를 토대로 하여 항공기의 설계단계에서부터 제작에 이르기까지 착각을 유발할 수 있는 구조적 요인을 제거해야 한다. 둘째로는 이러한 착각을 유발하지 않는 운항이나 기동방식을 택하여 비행임무를 수행토록 해야한다. 세째로 조종사들은 이러한 착각을 정상적인 인체의 반응에 의한 것이므로 자신에게도 당연히 일어난다는 사실을 용인해야 한다. 네째로 조종사들은 계기비행에 대한 구체적이고 실제적인 훈련을 통하여 계기비행 경험을 쌓아야 한다. 다음은 조종사들의 실제비행시 공간정위 상실현상에 봉착했을때의 처리요령이다. 첫째로 계기비행상황에서 자신의 감각과 계기가 일치하지 않을 때는 즉시 계기를 Cross Check하여 항공기의 자세나 기동형태를 정확하게 파악해야 한다. 둘째로 계기가 조종사의 의도대로 나타나도록 조작하고 이를 철저하게 의지하고 믿어야 한다. 세째로 자신의 감각과 계기가 일치할때까지 수평비행을 유지해야 한다. 그리고 마지막으로, 고성능 항공기가 계기비행중 저공에서 비행착각에 봉착하게 될때의 행동절차를 철저하게 숙지하고 있어야 한다.

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Development of Radiation Shield with Environmentally-Friendly Materials ; Ⅰ: Comparison and Evaluation of Fiber, Rubber, Silicon in the Radiation Shielding Sheet (친환경 소재의 의료 방사선 차폐 시트 개발 ; I: 섬유, 고무, 실리콘 소재 차폐 시트의 성능 비교평가)

  • Kim, Seon-Chil;Park, Myeong-Hwan
    • Journal of radiological science and technology
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    • v.33 no.2
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    • pp.121-126
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    • 2010
  • Traditionally, lead has been primarily used to shield the radiation in the hospital, because of its soft texture, durability and cost effectiveness. However, lead can be dangerous because of its toxicity when exposed to the human body, and it is classified as a heavy metal like cadmium, mercury, and arsenic etc. In order to compensate its noxious properties on the human body, researchers are trying to develop a radiation shield which has similar shielding efficiency and can also be manufactured in any form. In this study, sulfuric acid barium was mixed with fiber, rubber, and silicon all of which are harmless to the human body, tested, and evaluated for its ability of medical radiation shield. The result of this study showed that the sheet containing silicon and barium has the strongest shielding abilities.

Development of Syllabuses for Biological Nursing Science Subjects based on Learning Outcomes: Structure and Function of Human Body, Pathogenic Microbiology, Pathophysiology, and Mechanisms and Effects of Drugs (학습성과를 기반으로 한 기초간호학 교과목의 강의계획서 개발: 인체 구조와 기능, 병원미생물학, 병태생리학, 약물의 기전과 효과)

  • Park, Hyunju;Kim, Yun-Kyung;Kim, Joo Hyun;Jeong, Jae Sim;Choi Kwon, Smi;Hong, Hae Sook
    • Journal of Korean Biological Nursing Science
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    • v.17 no.2
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    • pp.188-210
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    • 2015
  • Purpose: The purpose of this study was to develop syllabuses of basic nursing science subjects (Structure and Function of Human Body, Pathogenic Microbiology, Pathophysiology, and Mechanisms and Effects of Drug) based on learning outcomes. Methods: We developed a 3-phase plan to develop the syllabuses. In the first phase, The Korean Society of Biological Nursing Science (KSBNS) held a workshop in May, 2013 in which professors who are in charge of basic nursing science subjects shared opinions about learning outcomes. As a result, initial prototype syllabuses came out. In the second phase, revised syllabuses based on learning outcomes were presented and discussed in the conference held by KSBNS in November, 2013. In the last phase, a research team who taught basic nursing science subjects finalized the syllabuses during the meetings. Results: Syllabuses of 4 basic nursing science subjects were developed. Conclusion: These syllabuses of 4 subjects need to be disseminated throughout nursing colleges. Further revision needs to be made according to the circumstances and context of each school.

Changes in gut microbiota with mushroom consumption (버섯 섭취와 장내 미생물 균총의 변화)

  • Kim, Eui-Jin;Shin, Hyun-Jae
    • Journal of Mushroom
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    • v.19 no.3
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    • pp.115-125
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    • 2021
  • Mushroom consumption causes changes in the immune system and gut microbiota via the actions of mushroom probiotic components. β-Glucan structure-related substances suppress secretion of inflammatory mediators, and induce macrophage activation, enhancing immunity and immune function. Substances other than directly useful components can be metabolized into short-chain fatty acids by gut microbiota. These short-chain fatty acids can then induce immunity, alleviating various diseases. Substances used to stimulate growth of health-promoting gut bacteria, thereby changing the gut microbiota community are defined to be probiotics. Probiotic altered intestinal microflora can prevent various types of bacterial infection from external sources, and can help to maintain immune system balance, thus preventing diseases. Research into beneficial components of Pleurotus eryngii, Lentinula edodes, Pleurotus ostreatus, Flammulina velutipes, Auricularia auricula-judae, and Agaricus bisporus, which are frequently consumed in Korea, changes in microbiota, changes in short-chain fatty acids, and correlations between consumption and health contribute to our understanding of the effects of dietary mushrooms on disease prevention and mitigation.

Differentiated QoS Provisioning of WBAN Traffic in WUSB Services based on IEEE 802.15.6 (IEEE 802.15.6 표준 기반 무선 USB 서비스의 차등화된 WBAN 트래픽 QoS 제공 방안)

  • Hur, Kyeong
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.18 no.5
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    • pp.1087-1095
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    • 2014
  • A recent major development in computer technology is the advent of the wearable computer system that is based on human-centric interface technology trends and ubiquitous computing environments. Wearable computer systems can use the wireless universal serial bus (WUSB) that refers to USB technology that is merged with WiMedia PHY/MAC technical specifications. In this paper, we focus on an integrated system of the wireless USB over the IEEE 802.15.6 wireless body area networks (WBAN) for wireless wearable computer systems supporting U-health services. And a communication structure that can differentiate QoS of U-health WBAN and WUSB traffic with different priorities is proposed for WUSB over IEEE 802.15.6 hierarchical protocol. In our proposal and performance evaluation, throughputs of U-health WBAN and WUSB traffic are analyzed under single and multiple QoS classes to evaluate the effectiveness of proposed QoS differentiating structure in WUSB over IEEE 802.15.6.