Journal of Mushroom (한국버섯학회지)

The Korean Society of Mushroom Science (한국버섯학회)
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Changes in gut microbiota with mushroom consumption

버섯 섭취와 장내 미생물 균총의 변화

  • Kim, Eui-Jin (Department of Biochemical Engineering, Chosun University) ;
  • Shin, Hyun-Jae (Department of Biochemical Engineering, Chosun University)
  • 김의진 (조선대학교 공과대학 생명화학공학과) ;
  • 신현재 (조선대학교 공과대학 생명화학공학과)
  • Received : 2021.09.09
  • Accepted : 2021.09.17
  • Published : 2021.09.30
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Abstract

Mushroom consumption causes changes in the immune system and gut microbiota via the actions of mushroom probiotic components. β-Glucan structure-related substances suppress secretion of inflammatory mediators, and induce macrophage activation, enhancing immunity and immune function. Substances other than directly useful components can be metabolized into short-chain fatty acids by gut microbiota. These short-chain fatty acids can then induce immunity, alleviating various diseases. Substances used to stimulate growth of health-promoting gut bacteria, thereby changing the gut microbiota community are defined to be probiotics. Probiotic altered intestinal microflora can prevent various types of bacterial infection from external sources, and can help to maintain immune system balance, thus preventing diseases. Research into beneficial components of Pleurotus eryngii, Lentinula edodes, Pleurotus ostreatus, Flammulina velutipes, Auricularia auricula-judae, and Agaricus bisporus, which are frequently consumed in Korea, changes in microbiota, changes in short-chain fatty acids, and correlations between consumption and health contribute to our understanding of the effects of dietary mushrooms on disease prevention and mitigation.

버섯의 섭취는 버섯의 유용 성분에 의해 면역체계 및 장내미생물균총의 변화를 유발한다. 그중 많이 알려진 β-glucan 구조 기반 물질들은 염증매개물질의 분비는 억제하고 대식세포의 활성은 유발하여 면역력의 증진을 도와인체의 면역기능을 증진시킨다. 직접적인 유용 성분 이외의 다른 물질은 장내 미생물균총에 의해 단쇄지방산으로 변화되며, 변화된 단쇄지방산은 면역 및 다양한 질병의 완화를 유발하게 된다. 버섯이 포함하고 있는 성분은 β-glucan 외에도 장내미생물균총을 변화하게 유도하는 prebiotic로써의 역할을 수행하게 된다. 변화된 장내미생물균총은 외부로부터 들어오는 다양한 감염성 균의 감염을 막으며, 면역체계의 균형 유지를 도우며, 질병을 예방하게 된다. 국내 섭취 빈도가 높은 새송이, 표고, 느타리, 팽이, 목이, 양송이 버섯의 유용 성분의 탐색, 장내미생물균총의 변화 및 섭취 시 인체의 단쇄지방산 변화 연구는 추후 버섯의 유용 성분, 장내미생물 및 질병과의 인과관계를 풀어내는데 기여할 것으로 여겨진다.

Keywords

Acknowledgement

본 연구는 산림청 산림과학기술개발사업(2020191B10-2022-BA01)에 의해 이루어진 것으로 이에 감사드립니다. 본 연구는 2021년도 정부(교육부)의 재원으로 한국연구재단의 지원을 받아 수행된 기초연구사업임(2021R1I1A1A01057538)

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