• Korean Journal of Biological Psychiatry
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• v.5 no.1
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• pp.71-82
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• 1998

The neuropsychiatric sequelae of traumatic brain injury are effects on complex aspect of cognition, emotion and behavior. They include problems with attention and arousal, concentration, executive function, intellectual changes, memory inpairments, personality changes, affective disorders, anxiety disorders, psychosis, apathy, aggression, and irritability. There are many useful therapeutic approaches available for people who have been brain injuries. Although a multifactioral, multidisciplinary, collaborative approach to treatment is proposed, for purposes of exposition the author have divided treatment into psychopharmacological, cognitive, behavioral, psychological, and social interventions.

• Journal of The Korean Society of Inherited Metabolic disease
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• v.1 no.1
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• pp.5-12
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• 2001

아시아 및 한국에서 처음 발견된 3명의 소아 Ethylmalonic encephalopathy (EE) 환자들은 riboflavin을 이용한 치료법에 점진적인 호전을 보인 것으로 나타났다. Ethylmalonic aciduria가 3가지 효소-2-methyl-branched-chain acyl CoA dehydrogenase (2MBCAD), iso-valeryl CoA dehydrogenase (IVCAD), 그리고 short-chain acyl CoA dehydrogenase (SCAD) - 들의 부분적인 결함으로 생긴다는 가설하에 dehydrogenase (탈수효소)의 보조 효소인 riboflavin이 부분적으로 나마 치료 과정에서 어떤 역할을 수행하는지의 여부를 살펴보았다. 다음의 세 증례에서 riboflavin 혹은 coenzyme Q10을 병행하여 치료한 결과 인지 행동(cognitive behavior)과 만성 점액성 설사(chronic mucoid diarrhea)가 호전된 것으로 관찰되었다. 또한, 치료 후 운동 기능도 일부 호전되었다. EE의 질병 발생 기전이 현재까지 완전히 밝혀지지는 않았지만, 세 명의 EE 환자들의 치료경과를 관찰하여 위의 가설을 뒷받침 할 수 있었다.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.26 no.2
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• pp.75-85
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• 2015

Internet gaming disorder (IGD), one of the common subtypes of internet addiction, is now classified in Section 3 of DSM-5 and is increasingly regarded as a growing health concern in many parts of the world. Consequently, many psychotherapeutic and psychopharmacological approaches have been considered and some research regarding therapeutic strategies has been conducted. However, treatment of IGD is in its early stages and therefore is not yet well established. This article reviews multiple therapeutic modalities including our own treatment model for IGD according to clinical and biological effects, thus providing suggestions for standard treatment strategies. The two main streams are psychopharmacological treatment and cognitive-behavior treatment, and the cognitive-behavior approach includes cognitive reconstruction, psychoeducation, and parenting coach. Many other non-pharmacological treatments are also recommended for personalized treatment of IGD.

• Journal of Music and Human Behavior
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• v.20 no.1
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• pp.75-97
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• 2023

This study aimed to investigate the effect of cognitive-motor interaction-based instrument playing on the early social skills of children with autism spectrum disorder (ASD). Nine children with ASD, averaging 5.6 years of age, participated in twelve individual sessions lasting 30 minutes each. The intervention comprised five stages: self-regulation, motivation to engage in social interaction, acceptance of a partner in co-playing activities, interpersonal coordination with a partner, and engagement in joint music playing. To evaluate changes in early social skills, joint attention and social interaction behaviors were observed, and the Social Responsiveness Scale (SRS-2) was administered pre- and post-intervention. Social synchronization was measured through a dyadic drum task, measuring synchronization accuracy, duration, and timing. Following the intervention, all nine children demonstrated increased early social behaviors, although there were no significant differences in SRS scores. Moreover, synchronized movement improved significantly in accuracy and maintained duration but not in reaction time. This study highlights the significance of recognizing the cognitive-motor interplay as crucial element in facilitating early social skills development in children with ASD.

• Journal of Music and Human Behavior
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• v.16 no.1
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• pp.73-88
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• 2019

This research was conducted to compare the rhythm reproduction abilities between older adults with and without mild cognitive impairment (MCI) and analyze the abilities depending on the rhythm idiom. Participants between 60-85 years of age were recruited from senior community centers, dementia prevention centers, and senior welfare centers. A total of 57 participants were included in this study: 27 diagnosed with MCI and 30 healthy older adults (HOA). The experiment was conducted individually in a private room in which a participant was given random binary time rhythm idioms and instructed to reproduce the rhythmic idioms with finger tapping. Each participant's beat production was recorded with the Beat Processing Device (BPD) for iPad. BPD calculated rhythm reproduction as measured through rhythm ratio and error among beats. Results showed marginal differences between the two groups in terms of mean scores of rhythm reproduction abilities. In terms of the rhythm ratio among beats, both groups' highest rhythm reproduction rate was for <♩ ♩>, and their lowest reproduction rate was for <♩. ♪>. In conclusion, there was no significant difference in rhythm reproduction ability between the HOA and MCI groups. However, the study found an interesting result related to performance level of rhythmic idioms. This result provides therapeutic insight for formulating rhythm tasks for older adults.

• The Journal of the Korea Contents Association
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• v.22 no.5
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• pp.393-403
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• 2022

This study tried to derive implications by analyzing the literature related to food psychology to understand the psychological and emotional influence of food. The results of an exploratory study on food psychology are as follows. First, it was found that the perception of taste is related to an individual's state of mind. Second, as the theories for understanding the psychological aspects of food intake, the eating inhibition theory, the emotion regulation theory, and the escape model for binge eating based on the narcissistic theory were confirmed. Third, it was found that tools that can measure symptoms related to binge eating occupy a large portion of food-related diagnostic tools. Fourth, research on food-related psychological disorders was conducted on food cravings, binge eating disorder, bulimia nervosa, eating inhibition, and healthy food obsession. Fifth, it was found that studies related to the treatment of food-related psychological disorders were focused on the cognitive behavioral therapy approach. This study will serve as a basis for understanding and intervening in the emotional impact of food and psychological problems related to food.

• Journal of the Korea Convergence Society
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• v.10 no.2
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• pp.325-330
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• 2019

The purpose of this study was to verify the physical activity planning behavior theory model of rehabilitation center users. For this purpose, a questionnaire survey was conducted for sports athletes who visited the sports rehabilitation hospital and rehabilitation center in the metropolitan area. A total of 203 questionnaires were used for the actual analysis. The collected data were analyzed using SPSS 18.0 and AMOS 18.0. In this way, we confirmed that intention has a significant direct effect on the behavior in the application of the physical activity planning theoretical model based on the social cognitive theory of rehabilitation center participants.

• Journal of Life Science
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• v.29 no.6
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• pp.747-753
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• 2019

Cognitive decline is characterized by reduced long-/short-term memory and attention span, and increased depression and anxiety. Such decline is associated with various degenerative brain disorders, especially Alzheimer's disease (AD) and Parkinson's disease (PD). The increases in elderly populations suffering from cognitive decline create social problems and impose economic burdens, and also pose safety threats; all of these problems have been extensively researched over the past several decades. Possible causes of cognitive decline include metabolic and hormone imbalance, infection, medication abuse, and neuronal changes associated with aging. However, no treatment for cognitive decline is available. In neurodegenerative diseases, changes in the gut microbiota and gut metabolites can alter molecular expression and neurobehavioral symptoms. Changes in the gut microbiota affect memory loss in AD via the downregulation of NMDA receptor expression and increased glutamate levels. Furthermore, the use of probiotics resulted in neurological improvement in an AD model. PD and gut microbiota dysbiosis are linked directly. This interrelationship affected the development of constipation, a secondary symptom in PD. In a PD model, the administration of probiotics prevented neuron death by increasing butyrate levels. Dysfunction of the blood-brain barrier (BBB) has been identified in AD and PD. Increased BBB permeability is also associated with gut microbiota dysbiosis, which led to the destruction of microtubules via systemic inflammation. Notably, metabolites of the gut microbiota may trigger either the development or attenuation of neurodegenerative disease. Here, we discuss the correlation between cognitive decline and the gut microbiota.

• Korean Journal of Psychosomatic Medicine
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• v.24 no.2
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• pp.200-207
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• 2016

Objectives : Alzheimer's disease(AD) is characterized by progressive decline of cognitive function and also by various behavioral psychological symptoms of dementia(BPSD) which causes distress to their caregivers. The purpose of this study was to investigate association between each AD patients' behavioral psychological symptoms and their caregivers' burden. Methods : Participants were 80 AD patients and their caregivers. We used Korean neuropsychiatric inventory (K-NPI) to assess the symptoms of patients and Korean version of Zarit Burden Interview(ZBI) to evaluate caregivers' burden. Results : The results showed ZBI score, which is the index for caregivers' burden, had a statistically significant positive correlation with the frequency of delusion, hallucination, agitation/aggression, depression, anxiety, disinhibition and irritability, the severity of hallucination, agitation/aggression, anxiety, disinhibition, aberrant motor, and sleep, and the global score(frequency${\times}$severity) for delusion, hallucination, agitation/aggression, depression, anxiety, disinhibition, aberrant motor, and sleep. There were significant correlations between each scale for cognitive function(i.e. MMSE-KC, CDR, GDS) and ZBI scale. Correlations between each scale for activity of daily living(i.e. Barthel -ADL, K-ADL) and ZBI scale were also significant. Conclusions : There were a significant correlation between BPSD and caregiver burden. Caregiver burden was also correlated with cognitive function and activity of daily living. Early detection and preventive treatment of these symptoms in BPSD might make improvement of caregivers' quality of life as well as AD patients'.

• The Journal of the Korea Contents Association
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• v.19 no.12
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• pp.604-614
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• 2019

The purpose of this study is to evaluate the effects of the acceptance commitment therapy program (ACT) on the psychological flexibility, self-compassion, recovery in alcohol dependents. The ACT program contains skills that establish acceptance and willingness, defusion, self-as-context, contact with the present moment, clarifying values, and committed action. This study was intended to enhance the effects on the psychological flexibility, self-compassion, recovery in alcohol dependents with ACT program. Fifteen inpatients with alcohol dependence were participated in the ACT group and the same number of participants were in the both CBT control group and TAU control group. The ACT program was held once a week, eight times, and each session was 90-minute long. Repeated measure of MANOVA and post-hoc were used to compare pre-test mean with post-test and with follow-up test mean. As a result of ACT program, positive changes were assured in the psychological flexibility including acceptance, cognitive defusion, being present, committed action and the increase of self-compassion and of recovery in alcoholics.