• Parasites, Hosts and Diseases
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• v.26 no.4
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• pp.239-244
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• 1988

In order to observe the antigenic fractions in saline extract of adult Paragonimus westermani, proteins in the crude extract were separated by sodium dodecyl sulfate-polyacylamide gel electrophoresis(SDS.PAGE) in reducing conditions. The separated protein fractions were transferred to nitrocellulose paper on which 20 sera from human paragonimiasis were reacted and immunoblottrd. Out of 15 stained protein bands in SDS-PAGE, 7 reacted with infected sera while 8 did not. Additionally, 7 unstained protein bands in SDS-PAGE reacted with the sera. Of 14 reacted bands, 30 kilodalton(kDa) band was the most frequently reacted (95%) and was a strong antigen. Protein bands of 23 and 46 kDa were also strong antigens. Bands of over 150 kDa, 120 kDa, 92 kDa, 86 kDa, 74 kDa, 62 kDa, 51 kDa, 32 kDa, 28 kDa, 16.5 kDa and 15.5 kDa were also reactive but their frequencies of the reaction were variable. Key words: Paragonimus westermani, human paragonimiasis, antigenic proteins, SDS-PAGE/ immunoblot

• The Journal of Engineering Geology
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• v.17 no.3
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• pp.455-469
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• 2007

The study area, Bonggil-ri, Gyeongju, SE Korea, is composed of Cretaceous sedimentary rocks, and Tertiary igneous rocks and dykes. A research on fracture developing history and density distribution was carried out on well exposed Tertiary granites. The fractures developed in this area have the following sequence; NW-SE trending duo-tile shear bands (set a), NNW-SSE trending extensional fractures (set d), WNW-ESE trending extensional or normal fractures (set b), NE-SW trending right-lateral fractures (set c), WNW-ESE trending reverse fault reactivated from normal faults (set e) and NW-SE trending left-lateral faults reactivated from shear bands (set a) under brittle condition. According to the result of fracture density analysis, the fracture density in this area depends on rock property rather than rock age, and also higher fracture density is observed around fault damage zones. However, this high fracture density may also be related to the cooling process associated with dyke intrusion as well as rock types and fault movement. Regardless of the reason of the high fracture density, high fracture density itself contributes to fluid flow and migration of chemical elements.

• Journal of Life Science
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• v.28 no.10
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• pp.1233-1243
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• 2018

Sterol regulatory-element binding proteins (SREBPs) are a family of transcription factors that regulate lipid homeostasis and metabolism by controlling the expression of enzymes required for endogenous cholesterol, fatty acid (FA), triacylglycerol, and phospholipid synthesis. The three SREBPs are encoded by two different genes. The SREBP1 gene gives rise to SREBP-1a and SREBP-1c, which are derived from utilization of alternate promoters that yield transcripts in which distinct first exons are spliced to a common second exon. SREBP-2 is derived from a separate gene. Additionally, SREBPs are implicated in numerous pathogenic processes, such as endoplasmic reticulum stress, inflammation, autophagy, and apoptosis. They also contribute to obesity, dyslipidemia, diabetes mellitus, and nonalcoholic fatty liver diseases. Genome-wide analyses have revealed that these versatile transcription factors act as important nodes of biological signaling networks. Changes in cell metabolism and growth are reciprocally linked through SREBPs. Anabolic and growth signaling pathways branch off and connect to multiple steps of SREBP activation and form complex regulatory networks. SREBPs are activated through the PI3K-Akt-mTOR pathway in these processes, but the molecular mechanism remains to be understood. This review aims to provide a comprehensive understanding of the role of SREBPs in physiology and pathophysiology at the cell, organ, and organism levels.

• Journal of Korean Elementary Science Education
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• v.24 no.4
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• pp.337-344
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• 2005

The purpose of this study is to analyze field trip activities in the elementary school science textbook developed under the 7th national curriculum. The results indicated there was an average of 4.25 field trip activities each semester presented in the textbook from the 3rd to 6th grade, mostly related to earth science and biology. The places for field trips were limited to in-school environment and natural sites in communities, and mostly purported to gain understanding of rudimentary concepts. Field trip activities were intended to facilitate science knowledge and understanding in order to integrate with the textbook content rather than offering students simple one-time activities. Most activities in the textbook guided students step by step. The starting or follow-up activities in the fields trips and reminder for cautions were not clearly presented. In order for the field trips to integrate with the content of the curriculum in the text book, they have to be presented in the textbook systematically. It is also imperative to find out various fold trip places related to the content in the curriculum, develop efficient activities dealing with science at the appropriate level for students and increasing interests in science and its teaming.

• Journal of the Korean Society for Library and Information Science
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• v.52 no.2
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• pp.5-25
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• 2018

This study is a broad examination researchon LIS students' perception about public library's subject special services and subject special librarian. Students majoring in Library and Information Science as respondents, it examined the recognition level of subject special services and subject special librarian, cognition level of necessity, competencies of subject special librarians and students and opinions on special status system of subject psecial librarians. Main factors shown in the results include the the level of students' understanding and necessity of subject special services and subject special librarian, students' willingness to work as a subject special librarian, the willingness to put additional effort into equip themselves with competencies as subject special librarians. There were respondents who have equipped competencies as subject special librarians through courses provided by the department of Library and Information Science and school curriculum but have not done anything further. Respondents responded that there is a need to systematize special status system of subject special librarian and that subject specialty is important in implementing subject special services but that there is a lack of subject specialty. Based on the research results, this study suggests that there is a need to put more emphasis on developing curriculum that can help overcoming difficulties faced by students majoring in Information Sciecne and help them become competent subject special librarians.

• Journal of Navigation and Port Research
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• v.45 no.3
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• pp.173-180
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• 2021

Although accounting is one of the core fields of corporate management, few studies have reported accounting phenomena involving shipping companies. In addition, although financial reporting is very important to shipping companies that use several financial tools such as ship finance and financial lease, it is difficult to identify studies investigating shipping companies' financial reporting, especially their earnings management. The purpose of this study is to analyze accrual earnings management behavior of shipping companies. Companies with high debt ratios and net losses are known to have incentives for earnings management. Due to the nature of the industry, shipping companies have a high debt ratio and often report net losses. Accordingly, shipping companies are expected to engage in substantial earnings management. Based on the analysis of KOSP I companies listed on the Korea Exchange from 2001 to 2020, it was found that shipping companies are engaged in higher levels of earnings management than non-shipping companies. Discretionary accrual was used as a proxy variable for earnings management. Discretionary accrual was measured using the modified Jones model of Dechow et al. (1995) and the performance matched model of Kothari et al.(2005). In this study, significant results were derived by comparatively analyzing the earnings management practices, which is one of the major accounting behaviors of shipping and non-shipping companies. Stakeholders such as external auditors, investors, financial institutions, analysts, and government authorities need to be aware of the earnings management behavior of listed shipping companies during their external audit, financial analysis, and supervision. Finally, listed shipping companies must conduct stricter accounting based on accounting principles.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.20 no.7
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• pp.535-546
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• 2019

The purpose of this research was to analyze the relationship between human risk factors and evacuation behavior stages for tunnel safety. Therefore, we conducted a survey using a structured questionnaire on the relationship between safety facilities and safety behavior in order to derive an optimized interaction between the two. The research subjects were 141 tunnel users who understand the tunnel environment. The survey period was from June 24, 2018, to September 28, 2018. As data analysis methods, we employed a frequency analysis, a multiple regression analysis, and an independent-sample t-test. In the analysis of the correlation between the human risk factors and the major variables of evacuation behavior, the evacuation phases 1, 2, and 3 were all correlated with acceleration and delay, and the human risk factors were partially correlated. In the multiple regression analysis, the will to comply with laws (${\beta}=0.188$, p=0.034) and information recognition within the tunnel (${\beta}=0.220$, p=0.009) were factors that influence the relationship between human risk factors and evacuation behavior, indicating 12% explanatory power of the impact of human risk factors for the acceleration of evacuation behavior 3. The important variables between human risk factors and evacuation behavior were compliance with laws and information recognition in tunnels. Hence, it is necessary to study the elements that interact with the environment in the tunnel.

• Journal of Korean Elementary Science Education
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• v.41 no.3
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• pp.480-500
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• 2022

In this study, the perception and demands on the use of realistic content were analyzed through in-depth interviews with elementary school teachers experienced in using realistic content in science classes. Specifically, the following questions were investigated: (1) What kind of realistic content and how do elementary school teachers use it in science classes? (2) What are the perceptions and difficulties of elementary school teachers regarding the use of realistic content in science classes? (3) What are the needs of elementary school teachers related to the professional development program for the use of realistic content in science classes? The study revealed the following results. First, elementary school teachers mainly used digital textbooks and realistic content provided by the "Science Level Up" site, and the content types could be classified into "exploration type," "visit type," and "production type," according to the purpose of use. Second, elementary school teachers mentioned the educational advantages of using realistic content to help students understand scientific content, induce interest and curiosity, and become immersed in a sense of reality. Several difficulties related to the use of realistic content were mentioned. Among them, the lack of high-quality educational content suitable for science classes and a lack of examples of specific class cases that use realistic content stood out. Thirdly, regarding the development of teacher expertise to use realistic content, elementary school teachers emphasized the need for information on quality realistic content; teacher training centered on specific class cases; instructional models that can be applied by realistic content type; and information on the purchase, use, management, and operation of necessary devices. Reflecting on these research results, implications for more effective use of realistic content in elementary science classes were discussed.

• Korean Journal of Forensic Psychology
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• v.11 no.2
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• pp.211-239
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• 2020

This study examined characteristics and judges' judgments regarding sexual violence cases against individuals with intellectual disabilities by analyzing total 716 cases of court decision. Of 716 cases, 6.0% sentenced not guilty, 53.5% imprisonment, 36.7% suspended sentence. More than half of the victims had experienced sexual assault more than one time with the tendency of repeating being higher when the accused were relatives or acquaintances to the victims. In half of the total cases, the victims were not able to specify the time of incidents. Only in 20% of the cases, there was actual compulsion but in the remaining cases, there was no clear coercion used during the crimes. There are three issues regarding court's decision of sexual assault case against individuals with intellectually disabilities; (1) credibility of victims' statement, (2) inability of resist during the crimes, and (3) whether the accused were aware of the victims's disabilities. In the judgment of credibility of statement, consistency of statement was the criterion that was used most frequently, being followed by specificity of statement, motivation for false accusation, cognitive capacity of victim, and reports of statement validity analysis in the order. The most frequently used criterion of inability to resist was the victim's statement and attitude, followed by the statement and attitude of the accused, the victim's knowledge and understanding of sexuality in the order. Regarding to the awareness of disabilities on the part of the accused, the statement and attitude of the accused was most frequently used, the victims' communicative abilities, duration of relationship, and daily life competence in the order. There were no differences in the rulings and issues according to levels of disabilities and gender. When victims were under 13 credibility of statement became more argues but the awareness of disabilities less frequently than the cases of victims who were 13 or older.

• Communications of Mathematical Education
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• v.36 no.1
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• pp.73-88
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• 2022

Mathematics is a way of thinking. To do mathematics means to think mathematically. In other words, mathematics education and mathematics literacy are related. In elementary and secondary school mathematics education in many countries, teaching of mathematics using textbooks is conducted mostly in their native language. So mathematics education takes place while reading, writing, listening, and speaking mathematics. Analysis of mathematics textbooks for the lower grades of undergraduate mathematics shows that most advanced countries in mathematics use excellent undergraduate mathematics textbooks written in their native language. However, the ratio of using imported textbooks from foreign countries is particularly high in the case of textbooks for mathematics majors at Korean universities. In this article, the effect of language used in university mathematics education is analized. In particular, the importance of high-quality leading-edge university mathematics textbooks in native language is introduced by analyzing the case of Bourbaki in France and 'War of language' at the Israel Institute of Technology. The innovation of French university mathematics education in the 20th century began with Bourbaki's 'Fundamentals of Mathematics', a French textbook written in his native language. Israel's Technion and the Hebrew University of Jerusalem continue to teach all subjects in their mother tongue. This has led to produce many Nobel Prize and Fields medal winners in these two countries. This study shows that textbooks and languages used in university mathematics education has affected mathematical literacy.