• The Korean Journal of Applied Statistics
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• v.22 no.5
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• pp.1085-1096
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• 2009

Population stratification can cause spurious associations between genetic markers and disease locus. In order to handle this population stratification in haplotype-based case-control association studies, we added population indicators as covariates to the haplotype trend regression model proposed by Zaykin et al. (2002). We investigated through simulations how both population stratification and measurement error in the estimation of true population of each individual affect type I error probabilities of the association tests based on both Zaykin et al.'s (2002) model and the proposed model. Based on those results, in the situation that there exists population stratification but there is no error in population classification of each individual, our proposed model does satisfy a type I error probability whereas Zaykin et al.'s (2002) model does not. However, as the measurement error increases, a type I error probability of our model correspondingly becomes larger than a nominal significance level. It implies that as long as uncertainty in the estimation of true population of each individual still remains, it is nearly impossible to avoid false positive in case-control association studies based on haplotypes.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.13 no.5
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• pp.2251-2258
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• 2012

This study compared the unweighted sample design, frequency weighted sample design and complex sample design to using 2009 Korea National Health and Nutrition Examination Survey in an effort to identify whether or not there is any difference in potential risk factors. Pearson chi-square test and Rao-scott chi-square test were applied to the analytic methods. As a result of analyses, all the variables were overestimated as significant risk factors in case of the unweighted sample design to which only the frequency weights were applied. In addition, there were differences in the confidence levels and results from the simple random sampling analysis and complex sample design to which no weight was applied. It is necessary to carry out the complex sample design rather than the analysis to which the frequency weights are applied, in order to ensure the findings to represent the whole population when our national statistics data is used.

• 한국사회정책
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• v.23 no.2
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• pp.173-200
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• 2016

This study has two objectives. First, this study examines subjective well-being among elders that operationalize life satisfaction and aging anxiety, guided by life-course perspective. Second, it examines the relationship between subjective well-being and age-friendly environment factor structure among age-cohort groups. This study employs the stratified sampling method from 4,000 Seoul citizens. Main findings from the multivariate regression analyses include: (1) as age increases, aging anxiety levels appeared to be higher, while decreasing the life satisfaction. (2) a substantially larger variance of life satisfaction and aging anxiety was accounted for by demographic variables and age-friendly environments across age-cohort groups. (3) the influence of age-friendly environment factors such as neighborhood problems, accessibility to social activities, social services and parks on subjective well-being was different across age-cohort groups. This study discusses the policy and practical implications of the results.

• Journal of agricultural medicine and community health
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• v.38 no.1
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• pp.1-13
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• 2013

Objectives: This study is to investigate the prevalence and related factors of metabolic syndrome among Korean adults aged 20 years and above. Methods: From the database of the $5^{th}$ Korea National Health and Nutrition Examination Survey (KNHANES V) conducted in 2010, data of 5,670 adults who responded to all the questionnaires of health interview and had metabolic syndrome in the health examination were included in this analysis. SAS 9.2 was used for statistical analysis with complex sample survey modules and commands. Results: The prevalence rate of metabolic syndrome based on the criteria proposed by International Diabetes Federation (IDF) was 18.8%. The prevalence of metabolic syndrome in each group was: 20.7% of women, 43.1% among elderly over 70 years old, 40.6% of the divorced or the separated, 27.6% of recipients of economic support from the government, 23.6% of people who had alcohol dependency problem, and 43.7% of overweight or obese adults. Independent risk factors based on the multiple logistic regression analysis revealed that prevalence of metabolic syndrome was associated with female (odds ratio 1.59 [95% confidence interval 1.20-2.11]), age (50s 3.95 [2.11-7.37], 60s 5.62 [2.98-10.61], 70s 10.56 [5.25-21.25]), high school education (0.52 [0.37-0.74]), clerk occupation (2.14 [1.27-3.60]), divorced marital status (1.72 [1.15-2.59]), alcohol dependency (1.86 [1.16-2.98]), higher BMI (14.08 [10.60-18.70]). Conclusions: The metabolic syndrome is prevalent among Korean adult population according to IDF criteria. Several demographic characteristics and potentially modifiable factors are associated with metabolic syndrome. Identification of this high-risk group and management of these modifiable factors are warranted to reduce the prevalence of metabolic syndrome.

• Journal of agricultural medicine and community health
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• v.29 no.1
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• pp.133-145
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• 2004

Objectives: Depression is a major health concern that can be life threatening if not recognized and treated early. However, there is few report on the depressive disorder of Hansen disease patients in Korea. Therefore, the authors executed this study in order to check factors related to a depressive disorder of a Hansen disease patients and compare with factors to reach to a depressive symptoms of ordinary people with studying their life state and the trouble that Hansen disease patients were currently experiencing Method: The authors surveyed depressive symptoms using self-reported questionnaires in 74 Hansen disease patients and 84 controls. The severity of depressive symptoms was measured using Korean Form of Geriatric Depression Scale (KGDS) score. Result: Positive rate of depressive disorders among Hansen disease patients was 70.3% and that the referents was 31.0%. There is significant difference positive rate of depressive disorders between Hansen disease group and the referents in the factors such as gender, age, frequency of going out, familial type, and familial income. Depressive disorder of Hansen disease group was associated with sex, familial income. According to the multiple logistic regression, the odds ratios of the Hansen disease group versus referents, gender, familial income, frequency of going out were significant (p<0.05). Conclusion: Hansen disease patients had statistically significant higher depressive symptom score than the referents. Also, Hansen disease patients who have lower familial income were more likely to have depressive disorders. Therefore, Economical supports and policy are required for the Hansen disease patients.

• Journal of Korean Dental Hygiene Science
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• v.7 no.1
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• pp.69-81
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• 2024

Background: This study aimed to investigate the association between physical activity and periodontitis based on depression status in a representative sample of Korean adults. Methods: A total of 12,689 subjects who participated in the 7th Korea National Health and Nutrition Examination Survey (2016-2018) were examined. Depression was defined as a PHQ-9 score ≥ 10. Periodontal status was assessed using the community periodontal index, with periodontitis defined as a code ≥ 3. Physical activity categories were divided into a physical activity group and a non-physical activity group, considering the number of days and minutes spent on moderate and vigorous activities. Moderate activity was defined as causing slight breathlessness or a slightly elevated heart rate, while vigorous activity was defined as causing significant breathlessness or a rapid heart rate. Multivariable logistic regression analyses were adjusted for sociodemographic variables (age, sex, education level, and household income), oral and general health behaviors (use of floss and interdental proximal brush, current smoking), and systemic health status (diabetes and hypertension). All analyses utilized a complex sampling design, and subgroup analysis was performed to estimate associations stratified by depression (PHQ-9 ≤ 9 and ≥ 10). Results: Multivariable regression analysis revealed that among participants with depression, those who did not engage in physical activity were 2.65 times more likely to have periodontitis (odds ratio = 2.65, 95% confidence interval = 1.17-6.01). Conclusion: The study findings suggest that individuals who participate in any form of physical activity may be significantly less likely to develop periodontitis, particularly within the group experiencing depression.

• Journal of Preventive Medicine and Public Health
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• v.26 no.1 s.41
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• pp.110-125
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• 1993

This study was designed to determine whether non-violent criminal and normal control on the basis of concentration of levels of trace mineral and toxic metal by analysis of human scalp hair. The subjects were selected 87 nonviolent criminal from a prison population and 120 normal control from periodic health checks for study. Hair samples were taken from the napes and Minnesota Multiple Personality Inventory (MMPI) was performed also. Five trace mineral (Zn, Cu, Mg, Fe, Na) and two toxic metal (lead, cadmium) contents were determined by an atomic absorption spectrometer. The contents of zinc and magnesium in hair of non-violent criminal were significantly lower than the control group (p<0.01). In the case of lead and cadimum, mean value of criminal group was significantly higher than control group. Significantly higher T-score of MMPI was seen in non-violent criminal group fur psychopathic deviate (Pd), paranoia scale (Pa), and Mania scale (Ma) than control group, but T-score of depression scale (D) was significantly higher in the control group. In the non-violent criminal group, the content of copper inversely proportion to T-score of Hs, D, Hy, Pd, Mf, Pa, Pt, Sc, Si except Ma, also Zinc inversely proportion to T-score of Hy, Mf, Pa, Pt. These results suggest that difference of some hair mineral contents exist between criminal and normal control group. Thus further studies are necessary to determine whether violent and nonviolent criminal group attributed biochemical imbalance with carefully constructed and controlled studies.

• Journal of the Korean Association of Geographic Information Studies
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• v.1 no.2
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• pp.14-25
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• 1998

The purpose of this paper is to select proposed waste facilities sites after consideration of relative importance of siting factors. From the literature review we have established the siting factors affecting selecting waste facilities sites, and constructed hierarchy of siting factors to evaluate the relative importance of the factors using Analytical Hierarchy Process(AHP). After mail surveying of expert group, we have analyzed the relative importance of siting factors affecting waste facilities. We have constructed Geographic Information System(GIS) of raster type, based on seventeen theme maps of siting factors on waste facilities, to select the proposed waste facilities sites after consideration of the relative importance of the siting factors for Gyongsan city, in Korea. After applying linear combination method, and factor combination method to overcome the methodological limitations of land suitability analysis, we have found five proposed sites, where intersected with proposed sites obtained from the two methods. From this research we have found that 1) methodologically, using GIS for selection of proposed waste facilities sites turned out to be highly useful, 2) application of relative importance of siting factors and two methods of land suitability analysis in selection of proposed waste facilities sites are pertinent enough to provide valid and reliable results, and 3) the research methods and approach employed in this research will be highly useful in site selection of other major facilities.

• Journal of agricultural medicine and community health
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• v.30 no.1
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• pp.113-120
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• 2005

Objectives: The worldwide epidemic of obesity is reporting but also in Korea. But there are few studies reporting with a community-based longitudinal data in Korea. This issues objects to measure the prevalence and evaluate the trends of overweight based on the repeated cross-sectional studies at a rural community adults during 10 years. Methods: With 1990~1999 Yang-Pyeong Cohort Baseline Survey Dataset, BMI is calculated and Overweight is categorized according to the classification of overweight in adult by Korean Society for the Study of Obesity. Results and Conclusions: Crude BMI means at 1990 is estimated to $22.0Kg/m^2$ and at 1999, $24.4Kg/m^2$(p for trend<0.0001). Trends of age adjusted BMI has borderline significant, but that of Age and Sex adjusted BMI is statistically significant(p for trend=0.039). In male population the change of the overweight prevalence from 1990 to 1999 is 35%, and in female population the change is 21.9%(Z=0.55). Female has more increased prevalence than male, but the change is more dominant in male than in female. At a rural community, obesity has markedly been increasing during the past decade and female in a rural community has higher prevalence of overweight.

• Journal of Preventive Medicine and Public Health
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• v.24 no.3 s.35
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• pp.428-440
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• 1991

This study was conducted to estimate the prevalence rate of cervical cancer and to investigate its risk factors. 5,417 asymptomatic married women were screened from March, 1984 to December, 1990 in Taegu city. Of 5,417 examinees, 3,817 (70.46%) were normal, 1,542 (28.7%) showed inflammatory change, 51 (0.94%) were dysplasia and 7 (0.13%) were carcinoma in situ or invasive carcinomas. The prevalence of abnormal finding (dysplasia, carcinoma in situ or invasive carcinoma) was 1,070 per 100,000 population. The prevalence of dysplasia was 940 per 100,000 and that of carcinoma in situ or invasive carcinoma was 130 per 100,000. Age-adjusted prevalence rate for abnormal finding adjusted with standard population of Taegu city was estimated to be 850 per 100,000. The prevalence of cervical cancer was significantly increased with age (P<0.05). The prevalence of cervical cancer was significantly decreased with age at marriage and educational level (P<0.05). The history of induced abortion and the number of pregnancies were significantly associated with the prevalence of cervical cancer (p<0.05), whereas, the number of parity was not. Age at marriage was significantly associated with the prevalence of cervical cancer after stratification by age (p<0.05). However, the level of education, parity, induced abortion, number of pregnancies were not significant. Inflammation and human papiloma virus infection were associated with cervical cancer with odds ratio of 13.48 (95% confidence interval $7.80{\sim}23.40$) and 474.29 (95% confidence interval $196.80{\sim}1143.10$), respectively. In conclusion, for early detection of cervical cancer it should be recommended to perform mass cytological screening. In particular, regular and periodic cytologic screening, starting at age 25, for cervical cancer should be recommended for those women who have frequent cervical inflammation and for those women married before age of 20.