• Korean Journal of Cognitive Science
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• v.24 no.1
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• pp.1-24
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• 2013

The elderly population continues to increase in Korea and there has been a growing interest in understanding normal aging. In response to this public interest, the present paper reviewed human aging research focusing on recently published neuroimaging studies. For the first half of the paper, I reviewed the effects of aging on the brain and cognition. In normal aging, structural changes in the brain include atrophy and volume reduction in the prefrontal and temporal cortices. Functional changes are exhibited in the form of overactivation of the brain. Moreover, age-related cognitive decline is particularly observed in inhibition and memory, which are also associated with the age-related structural changes in the brain. For the second half of the paper, I introduced physical exercise studies showing that exercise played a protective role in the age-related neurocognitive decline. More specifically, engaging in physical exercise (particularly, aerobic exercise) for a relatively long period of time (e. g., > 6 mon.) protected older adults from volume loss in the prefrontal cortex and the hippocampus, and induced better inhibition and memory. These exercise-induced benefits appear to be associated with changes in neuronal levels, indicating that the aging brain is still plastic and this plasticity can be enhanced by physical exercise.

• Journal of the Korean Geographical Society
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• v.38 no.6
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• pp.906-921
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• 2003

This paper discusses the price effects of local growth controls on the housing markets of California jurisdictions in the late 1980s empirically. Particularly, based on spatial econometric modeling, the study focuses on the homebuilding constrained by growth controls which is one of the price effects. The modeling produces the California-wide generalizable results, differentiates among the individual effects of various growth controls on homebuilding, and covers spatial effects. Thereby, this study intends to supplement the existing work on the price effects of growth controls. The modeling results find that restrictive residential zoning had the effect of significantly restricting housing construction in the late 1980s. On the other hand, urban growth boundaries had the effect of accommodating homebuilding. Population growth or housing permit caps and adequate public facility ordinances had no significant effects on housing construction.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.14 no.7
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• pp.3326-3337
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• 2013

This study was performed to determine health-related dietary and lifestyle of characteristic factors associated with sodium hyperingestion of korean adults by sexual difference. Study subjects were 30~69years (n=1,622) adults who participated in the 2010 Korean National Health and Nutrition Examination Survey (KNHANES V-1). Subjects were divided into the hyperingestion group (HG, n=1,494) and normal ingestion group (NG, n=128) by 'WHO growth standard sodium intakes(2,000mg/day)' and the relationships between Comparison of demographics and physical measurement, eating behaviors and health-related factors were analyzed. By logistic regression method, risk factors for sodium hyperingestion group revealed in this study were gender(female), number of family', 'breakfast', 'lunch', 'dinner', 'nutrition labeling use'. and In case of male, risk factors for sodium hyperingestion group were 'lunch', 'dinner', 'self-rated body image' of eating behaviors. In case of female, Which were number of family' of demographics, 'breakfast', 'lunch', 'dinner' of eating behaviors. In these results, according to different sexual aspect of sodium hyperingestion, we suggest that nutrition label use and proper nutrition intake criteria among sexual, recognition promotion campaign along with education program for repressed sodium hyperingestion related to hypertension prevention of korean adults should include eating habits improvement and demographics lifestyle modification.

• Korea journal of population studies
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• v.3 no.1
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• pp.5-41
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• 1979

Vast volumes of studies of the medical and public health aspects of fertility and family planning have been published by the various institutes of health related research and university scholars in Korea. None of them, however, have dealed with the population problems associated with biologically and mentally handicapped people. It must be emphasized that the purpose of Korea's population policy should be to improve the quality of the population rather than to decrease its rate of increase. In this spirit, the first report of this study is to identify problems related with mentally and physically less fitted population, and to attempt to offer the possible solutions to the health planners and policy-makers. Several nation-wide surveys of the handicapped people in Korea have been compared. Each survey shows a wide range of difference in the prevalence of the handicaps(see Table 13). In this study, the data on the handicaps are collected by two independent system ; one by the nation-wide survey and the other by the reporting system existing at the Seoul National University Demonstration Health Project. The Chandrasekar-Deming technique was used to estimate the total number of handicaps. The estimates are summarized in the tables 8, 9 and 10. Estimate of total number of handicapped people in Korea is 601, 400 with the prevalence rate of 16.1 per thousand persons. Even if taking a number of conditions which may result in a biased estimate of the total number of the handicaps into consideration, the proportion of handicapped people in Korea has increased in the past two decade as the result of the rapid decline in fertility and childhood mortality, which consequently prolonged life expectancy of persons with congenital or acquired impediment. An increase in the proportion of handicapped people will eventually bring about serious problems of social welfare, medical care, and population qualities from various aspects including eugenics. To tackle the problem, there must be an increased emphasis on the prevention of handicaps from the government and private sector. Based on the amount and quality of data, and from the practical point of view, this study prepared a set of recommendations for the government to strengthen its programs of the preventive activities during the prenatal period and early childhood, early finding from routine examinations, and proper social and medical rehabilitation.

• Korean Journal of Human Ecology
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• v.22 no.1
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• pp.181-188
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• 2013

노인에게서 두드러지게 나타나고 있는 저근육형 비만은 근육감소를 동반한 체지방의 증가로 신체상의 뚜렷한 체성분의 변화를 야기 시킨다. 이때 골감소증을 동반하여 신체기능의 감소 및 골절장애 그리고 대사성 관련 질환의 위험도가 올라가는 것으로 보고되고 있다. 노화로 인한 체성분의 변화는 단순한 저근육형일 경우와 비만일 때 보다 급격히 증가된 복부내장 지방조직에서 분비되는 염증성 사이토카인, C-반응성 단백질(CRP), 인터루킨(IL)-6, IL-8 및 종양 괴사 인자(TNF-${\alpha}$)들이 단백질 대사를 저해하여 근육량의 감소를 더욱 촉진시키며, 염증관련 대사질환의 유병률에 중요한 요인이다. 본 연구에서는 DNA 메틸화가 당뇨병, 심혈관질환, 암과 같은 만성염증성 질환에 관계하고 있다는 최근 연구 결과를 기초로 하여 항염증 영양소와 생리활성을 갖는 식품인자들의 충분한 섭취가 염증조절에 중요하게 기여할 것으로 생각되며, 또한 염증성 질환의 주요 표식자인 DNA 메틸화와 히스톤 변형을 유발하는 효소의 활성 또는 비 암호화된 RNA의 발현을 조절함으로써 근육량 증가와 체지방 감소에 중요한 역할을 하는 것을 살펴보았다. 따라서 최근 새롭게 인식되는 후생유전학적 연구의 중심에 있는 항염증 영양소의 효과와 체성분 변화와의 긍정적 관계를 중심으로 저근육형 비만의 예방 및 인구고령화에 건강한 노화를 위한 효과적인 방법을 제시하였다.

• Proceedings of the Korea Water Resources Association Conference
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• 2011.05a
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• pp.304-304
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• 2011

최근 도시화에 따른 인구증가와 더불어 도로포장 등 불투수면적의 증가로 인하여 우기시 빗물 침투가 차단되어 도심의 지하수위가 저하되며 토양의 건토화, 열섬현상 등의 문제가 발생하게 되었다. 이러한 문제점에 착안하여 본 연구에서는 투수효과를 최대한 고려할 수 있는 고강도의 친환경 콘크리트 블록(에크스톤 바이오 블록; ECOSTONE-BIO BLOCK)을 개발하였으며 기존 콘크리트 블록의 자연적 빗물침투 억제의 문제점을 일부 개선하였다. 본 블록은 캡슐공법을 사용하여, 공극률은 높이면서(투수성 향상), 강도와 내구성이 유지됨은 물론 캡슐안에 황토성분을 첨가하여, 바이오적인 기능 및 재생골재를 이용한 친환경적 제품으로 투수성, 내구성, 기능성을 극대화 시켰다. 또한 제품표면은 천연 백색돌맹이, 흑색돌맹이의 배합으로 자연석재 느낌을 구현하였으며, 쇼트블라스트 및 커링 표면공정으로 미끄럼저항지수를 조절할 수 있어, 기존 콘크리트 보도블록에 비해 투수율, 내구성, 기능성, 안전성이 우수하여, 안전한 보행환경이 가능한 것으로 분석되었다. 마지막으로, 주변 환경과 잘 어울리도록 디자인된 바이오기능성 친환경 블록으로 도심지역 시공시 투수효과에 따른 지하수고갈방지 및 침수피해에 도움을 주리라 사료된다.

• Journal of the Korean Society of Food Science and Nutrition
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• v.4 no.1
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• pp.55-58
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• 1975

(1) 가족계획사업(家族計劃事業)이 10여년간(餘年間) 계속(繼續)되고 있으나 아직도 농촌(農村)에서는 그 성과(成果)가 저조(低調)한 것 같은데, 비단 농촌(農村)뿐만은 아니지만 전국적(全國的)으로 본사업(本事業)에 적극(積極) 주력(注力)하여 인구증가(人口增加)를 억제(抑制)하고 식량(食糧)을 위시(爲始)하여 식염(食鹽)의 소비량(消費量)도 줄이는 데 가일층(加一層) 노력(努力)해야 소득증대(所得增大)에도 이바지할 것으로 여긴다. (2) 도시(都市)가 농촌(農村)보다는 약간 덜 짜게 먹는 형편(形便)이기는 하나 하루 평균(平均) 섭취(攝取)해야 할 식염량(食鹽量)(20g)보다는 도시(都市)와 농촌(農村)이 다 같이 필요이상(必要以上)으로 4배(倍)나 많은 식염(食鹽)을 섭취(攝取)하므로 하루 빨리 소득증대(所得增大)를 모색(摸索)하여 채식위주(菜食爲主)의 식생활(食生活)에서 벗어날 수 있는 식생활(食生活) 개선(改善)이 있어야 하며 많은 식염(食鹽)의 섭취(攝取)에서 유발(誘發)되는 이차적(二次的) 부작용(副作用)을 추구(追究)하여 만일(萬一) 그것이 발견(發見)된다면 그 해결방안(解決方案)을 연구(硏究)해야 할 것이다. 이것에 또한 본연구(本硏究)의 더 큰 의의(意義)가 있다고 하겠다.

• Proceedings of the Korea Information Processing Society Conference
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• 2012.11a
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• pp.1292-1295
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• 2012

인구 과밀화 및 급격한 도시 팽창은 지상공간에서 거주하는 인간 삶의 질을 위협하고 있다. 따라서 지상공간의 개발을 억제하여 환경을 보호하고 도시 공간 이용의 효율성을 최대화하기 위해 지하 공간을 개발하고자 하는 움직임이 활발하다. 자연환경으로부터 격리된 구조인 지하공간은 지상공간에 비해 실내 공기 질을 쾌적한 상태로 유지하기 어려운 밀폐된 환경이므로 오랜 시간동안 상주하는 거주자 및 한시적 이용자들의 건강에 영향을 미치는 온도, 습도, $CO_2$, 먼지 등의 환경을 제어하기 위한 기술 개발이 필요하다. 본 연구에서는 지하공간의 쾌적도 향상을 위해 온 습도 및 $CO_2$, 먼지센서를 이용한 통합 센서를 제작하여 현재 지하공간의 환경정보를 실시간 모니터링하고 실내공간의 쾌적 지표를 기반으로 환풍기, 송풍기 등의 디바이스를 제어하기 위한 USN 기반의 환경제어시스템을 구현한다. 제안한 시스템을 통해 지하공간의 환경을 개선할 뿐만 아니라 고가의 계측 장비로 인한 비용 절감 및 이동성과 확장성 등의 부가적인 효과를 기대한다.

• Convergence Security Journal
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• v.14 no.6_1
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• pp.129-138
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• 2014

South Korea should correspond to the primary threat to North Korea's nuclear weapons. It is necessary to have countermeasures to solve the realistic problems of North Korea's nuclear weapons. We can intensify military pact between the United States and Korea and at the same time strengthening the current military power. Currently, we take note the threat North Korea's missile. We can not control the development of a nuclear weapon and there are possibilities that North Korea have successfully miniaturized nuclear enough to carry by the missile. We should overview and check the Korea's missile defenses system. While the direction of the overall missile defense system deployment with a focus on lower and upper air defense network. And discuss defense research should be to build a system that can be protected with a key strategic facilities and cities. While North Korea have nuclear weapon, the main issues related to North Korea's nuclear threat. The six party talks countries try to solve the problem by the international and diplomatic approach. At the same time we should make somewhat to defend measures such as military defenses of Kill chain system to protect our country. Kill Chain is on of the effective defense system. We know that North Korea do not abandon to develop nuclear weapons by diplomatic efforts. We should performed in fact by a variety of military suppression method.

• Journal of Life Science
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• v.22 no.11
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• pp.1500-1506
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• 2012

Transforming growth factor (TGF)-${\beta}$-dependent apoptosis is important in the elimination of damaged or abnormal cells from normal tissues, especially in liver, in vivo. To investigate which gene expressions are critical for TGF-${\beta}$-induced apoptosis in hepatocytes, gene expression profiling experiments were performed with TGF-${\beta}$-treated and non-treated mouse hepatocytes AML12 cells. Findings showed that serum and glucocorticoid-inducible protein kinase1 (SGK1) expression is markedly downregulated during TGF-${\beta}$-induced apoptosis. Findings confirmed that expression of SGK1 protein, as well as mRNA, is also markedly decreased with TGF-${\beta}$ treatment. Infection of adenoviral vector encoding constitutively active SGK1 (CA-SGK1), but not kinase dead SGK1 (KD-SGK1), attenuated TGF-${\beta}$-induced apoptosis. All of these results suggest that downregulation of SGK1 expression is critical for TGF-${\beta}$-induced apoptosis in AML12 cells.