• 한국전자현미경학회:학술대회논문집
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• 1994.05a
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• pp.9-10
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• 1994

• Korean Journal of Clinical Laboratory Science
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• v.56 no.1
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• pp.85-88
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• 2024

Electroencephalography (EEG) is a test that diagnoses epilepsy and measures brain function. During EEG, the space between the electrode and the skin is filled with a conductive paste to reduce the impedance between the electrode and the scalp, which helps measure the EEG signals. This study compared the artifacts of the two representative conductive pastes (Ten20 and Elefix). The artifacts, noise, and satisfaction were surveyed after using the two conductive pastes. The two conductive pastes had similar artifacts and noise, but the survey results showed that the Elefix conductive paste had better satisfaction and adhesion. This result may be explained by the imprinting effect according to the experience of using the Elefix conductive paste first in the EEG class. Hence, further research is needed.

• The Korean Journal of Nuclear Medicine Technology
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• v.14 no.1
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• pp.3-7
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• 2010

Purpose: The usefulness of Positron Emission Tomography (PET) images in diagnosis, staging, recurrent and treatment response evaluation has already been known. However, tumors which are small size, located in lower lobe of lung or upper lobe of liver are shown misalignment, distortion and different Standard Uptake Value (SUV) by respiration in PET images. Therefore, if radiotherapy based on normal respiration, it may cause low treatment response or more side effects because targets which had to treat, out of treat range or over dose to normal tissue. The purpose of this study is to evaluate attenuation-correction with Average CT (ACT) for more accuracy SUV measurement and minimize artifact by respiration. Materials and Methods: 13 patients, who had tumors which are around the diaphragm, underwent ACT scan after Helical CT (HCT) scan with PET/CT (Discovery DSTE 8; GE Healthcare). We quantified the differences between attenuation corrected image with HCT and attenuation corrected image with ACT in artifact size and maximum SUV ($SUV_{max}$). Artifacts were evaluated by measurement of the curved photogenic area in the lower thorax of the PET images for all patients. $SUV_{max}$ was measured separately at the primary tumors. Analysis program was Advantage Workstation v4.3 (GE Healthcare). Patients were injected with 7.4 MBq (0.2 $mC_i$) per kg of $^{18}F$-FDG and scanned 1 hour after injection. The PET acquisition was 3 minute per bed. Results: Significantly lower artifact were observed in PET/ACT images than in PET/HCT images (below-thoracic artifacts caused by under corrected $1.5{\pm}3.5$ cm vs. $13.4{\pm}4.2$ cm). Significantly higher $SUV_{max}$ were noted in PET/ACT images than in PET/HCT images in the primary tumor. Compared with PET/HCT images, $SUV_{max}$ in PET/ACT images were higher by $5.3{\pm}3.9%$ (mean value) tumor. The highest difference was observed in Lower lobe of lung (7.7 to 8.7; 13%). Conclusion: Due to its significantly reduced artifacts in lower thoracic, attenuation corrected image with ACT images provided more reliable $SUV_{max}$ and may be helpful in monitoring treatment response. Moreover, ACT can separate upper lobe of liver and lower lobe of lung, it may be helpful in interpretation. ACT will be clinically useful, considering increased dose caused by ACT scan and adapt.

• Proceedings of the Korean Society for Food Science of Animal Resources Conference
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• 2005.10a
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• pp.290-293
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• 2005

장내 단백질 가수분해효소에 의한 casein 분해산물들의 ACE 저해 활성을 비교하기 위하여 인공위액, 인공장액 및 인공위액과 장액 연속처리를 각각 반응조건으로 일정시간 casein을 가수분해한 후 각 효소 가수분해물이 혈압상승 peptide 생성효소인 Angiotensin converting enzyme(ACE)에 대한 저해활성을 측정하였다. 각 소화액에 따른 가수분해물은 모두 ACE 저해활성을 나타내었으며, 2시간 효소처리를 하였을 때, 인공위액, 인공장액, 인공위액과 장액 가수분해물은 각각 69%, 80% 및 88%로 최대 ACE 저해활성을 보였다. 그리고 casein의 가수분해 정도를 확인하기 위한 SDS-PAGE에서는 인공위액으로 처리한 군보다 인공장액으로 처리한 군이 더 작은 분자량으로 분해되는 것을 확인할 수 있었고, 인공위액과 장액을 함께 처리한 군에서는 1시간 안에 대부분의 분해가 이루지는 것을 관찰할 수 있었다.

• Proceedings of the Korean Society of Computer Information Conference
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• 2023.07a
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• pp.331-332
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• 2023

최근 ChatGPT, 코딩교육, 디지털교과서 등의 새로운 용어와 산물들이 전국 단위 언론사를 통해, 교육 전문가(교사 등)와 일반 국민들에게 어떤 형태의 보도가 진행되는지 확인하는 것이 중요한 연구 출발점이다. 본 연구는 오늘날 학교교육, 교육방법(매체론) 등에 큰 변화를 줄 '인공지능'에 대한 전국 단위 언론사(일간지-11개사, 방송사-5개사)의 최근(2020-2023년) 보도형태를 분석하고 제시하였다. 본 연구에서는 2020년 1월부터 2023년 5월까지(3년 5개월간) 총 16개 언론사(일간지와 방송사)에서 보도한 '인공지능'와 '학교' 용어가 모두 포함된 관련 뉴스 기사들을 분석하였다. 분석대상 뉴스 빅데이터들을 대상으로 연도별 보도기사 건수 분석, 키워드 트렌드 분석, 연관어 분석(워드클라우드 제시) 등을 진행하였다.

• The Korean Journal of Nuclear Medicine
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• v.39 no.3
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• pp.174-181
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• 2005

Purpose: Reduction of respiratory motion artifacts in PET images was studied using respiratory-gated PET (RGPET) with moving phantom. Especially a method of generating simulated helical CT images from 4D-CT datasets was developed and applied to a respiratory specific RGPET images for more accurate attenuation correction. Materials and Methods: Using a motion phantom with periodicity of 6 seconds and linear motion amplitude of 26 mm, PET/CT (Discovery ST: GEMS) scans with and without respiratory gating were obtained for one syringe and two vials with each volume of 3, 10, and 30 ml respectively. RPM (Real-Time Position Management, Varian) was used for tracking motion during PET/CT scanning. Ten datasets of RGPET and 4D-CT corresponding to every 10% phase intervals were acquired. from the positions, sizes, and uptake values of each subject on the resultant phase specific PET and CT datasets, the correlations between motion artifacts in PET and CT images and the size of motion relative to the size of subject were analyzed. Results: The center positions of three vials in RGPET and 4D-CT agree well with the actual position within the estimated error. However, volumes of subjects in non-gated PET images increase proportional to relative motion size and were overestimated as much as 250% when the motion amplitude was increased two times larger than the size of the subject. On the contrary, the corresponding maximal uptake value was reduced to about 50%. Conclusion: RGPET is demonstrated to remove respiratory motion artifacts in PET imaging, and moreover, more precise image fusion and more accurate attenuation correction is possible by combining with 4D-CT.

• Progress in Medical Physics
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• v.24 no.1
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• pp.76-83
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• 2013

Previous studies about effect of respiratory motion on diagnostic imaging and radiation therapy have been performed by monitoring external motions but these can not reflect internal organ motion well. The aim of this study was to develope the artificial pulmonary nodule able to perform non-invasive implantation to dogs in the thorax and to evaluate applicability of the model to respiratory motion studies on PET image acquisition and radiation delivery by phantom studies. Artificial pulmonary nodule was developed on the basis of 8 Fr disposable gastric feeding tube. Four anesthetized dogs underwent implantation of the models via trachea and implanted locations of the models were confirmed by fluoroscopic images. Artificial pulmonary nodule models for PET injected $^{18}F$-FDG and mounted on the respiratory motion phantom. PET images of those acquired under static, 10-rpm- and 15-rpm-longitudinal round motion status. Artificial pulmonary nodule models for radiation delivery inserted glass dosemeter and mounted on the respiratory motion phantom. Radiation delivery was performed at 1 Gy under static, 10-rpm- and 15-rpm-longitudinal round motion status. Fluoroscpic images showed that all models implanted in the proximal caudal bronchiole and location of models changed as respiratory cycle. Artificial pulmonary nodule model showed motion artifact as respiratory motion on PET images. SNR of respiratory gated images was 7.21. which was decreased when compared with that of reference images 10.15. However, counts of respiratory images on profiles showed similar pattern with those of reference images when compared with those of static images, and it is assured that reconstruction of images using by respiratory gating improved image quality. Delivery dose to glass dosemeter inserted in the models were same under static and 10-rpm-longitudinal motion status with 0.91 Gy, but dose delivered under 15-rpm-longitudinal motion status was decreased with 0.90 Gy. Mild decrease of delivered radiation dose confirmed by electrometer. The model implanted in the proximal caudal bronchiole with high feasibility and reflected pulmonary internal motion on fluoroscopic images. Motion artifact could show on PET images and respiratory motion resulted in mild blurring during radiation delivery. So, the artificial pulmonary nodule model will be useful tools for study about evaluation of motion on diagnostic imaging and radiation therapy using laboratory animals.

• Proceedings of the KIEE Conference
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• 2007.10a
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• pp.343-344
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• 2007

본 논문은 의사표현이 어려운 전신마비환자의 뇌파(EEG)를 이용하여 긍정과 부정을 표현할 수 있는 방법에 대해서 소개한다. 더 나아가 인간의 감정에 따라 긍정과 부정을 민감하게 반응하는 뇌 영역을 분석하였다. 해당영역의 뇌파(EEG)변화를 측정하기 위해 컴퓨터 시스템과 접목시키는 목적도 포함하고 있다. 이를 위해서 미약한 뇌파를 증폭 시키는 전치 증폭기를 구현하였고 인공산물과 뇌파 주파수영역만을 통과시키는 아날로그 전자회로를 구현하였다. 또한 인간의 두뇌피질로부터 측정된 신호는 컴퓨터 시스템에 전송된다. 수신된 신호를 실시간 Fast Fourier Transform(FFT) 신호처리과정을 거쳐 뇌파의 주파수 영역을 분류하게 된다. 이때 분류된 뇌파를 바탕으로 인간의 긍정과 부정을 표현할 수 있는 방법을 제시한다.

• The Korean Journal of Nuclear Medicine
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• v.38 no.6
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• pp.540-542
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• 2004

Although artifacts in tomographic imaging can arise from a number of sources, this case presents an artifact caused by using inadequate acquisition parameters which do not match the collimator with which a camera equipped in Tc-99m ECD brain SPECT. Whenever the collimator in tomographic studies is changed, we should take care to use suitable parameters of acquisition protocol according to the collimator with which a camera is fitted. Other ways to prevent an error of this type is to use a point source.

• Proceedings of the Korea Information Processing Society Conference
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• 2014.04a
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• pp.995-997
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• 2014

뇌파는 최근에 가장 많이 연구되고 있는 생체신호이다. 본 연구에서는 오픈 감정뇌파데이터인 DEAP Dataset를 활용한 데이터 분석 실험을 시행하였다. DEAP Dataset는 총 32개의 데이터이며, 32채널로 구성되어 있다. 전처리 과정에서는 디지털 필터인 IIR(Infinite Impulse Response) Filter를 사용하여 잡음을 제거하였고, 인공산물인 안구잡파(EOG: Electrooculograms) 제거에는 LMS(the Least Mean squares) 알고리즘을 사용하였다. 감정분류는 Valence-Arousal 평면을 사용하여 네 개의 감정으로 구분하였고, 분류 실험으로는 패턴인식 알고리즘인 SVM(support Vector Machine)를 사용하였다. 실험결과 SVM이 70%대의 결과를 도출하여 이전 실험결과보다 높은 정확도를 도출하였다.