• Knowledge Management Research
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• v.22 no.4
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• pp.283-301
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• 2021

RPA (Robotic Process Automation) technology has recently been spotlighted to preemptively respond to the 4th industrial revolution without spending a lot of time and money to improve various existing business and IT processes. In this study, variables affecting intention to use RPA technology were representatively identified into three positive factors and three negative factors, and the causal relationship between the effects of these variables on actual RPA acceptance intention was examined. After conducting an email survey for general office workers, structural equation analysis (SEM) was performed using SPSS 27.0 and SmartPLS 3.3.5. The second order factor of a positive perception consisting of security, accuracy, and efficiency, and the second order factor of a negative perception consisting of job security, execution error, and fear of introduction failure. The positive perception affected the intention to use RPA through perceived usefulness and perceived ease. It was confirmed that the negative perception has a mediating effect on the intention to use RPA through acceptance conflict. In addition, it was confirmed that the presence or absence of experience in using RPA interacts with perceived ease and has a moderating effect on intention to use RPA. It can be said that there is practical and theoretical implications from the point of view of knowledge management in that it allows companies to recognize and respond to which factors are important from the point of view of companies that want to use RPA.

• Journal of Life Science
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• v.32 no.6
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• pp.468-475
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• 2022

The functional distinction between stem and progenitor cells is well established in several tissues, particularly in the blood. There, hematopoietic stem cells preserve their self-renewal potential and reconstitution ability in the bone marrow niche. Bone marrow represents a unique setting in which to examine how stroma influences tissue function. It was the setting in which the experimental definition of a niche was first provided in mammalian stem cell biology and where clear evidence for non-cell-autonomous oncogenesis was first defined. The relationship between bone and blood is ancient as all animals since the divergence of fish that have bones and blood, make blood in their bones. This long coevolution engendered complex interrelationships, including the first proposed and first experimentally defined niche for stem cells in mammals. Multiple bone marrow stromal cell types serve as regulators of hematopoiesis, and the dysfunction of some causes myelodysplasia and leukemia. However, no comprehensive atlas of stromal subpopulations exists. Therefore, we think these data point to something of importance, such as how the needs and challenges of the organism become translated down to distinct cell types that critically govern specific functions within tissues and do so at the level of a single molecule. We think this will be of broad interest to those focusing on systems biology and the physiology of organisms, particularly those seeking a molecular basis for understanding cell and tissue behavior. We summarized the current and emerging concepts of hematopoietic stem cells and bone marrow niche.

• Journal of Applied Biological Chemistry
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• v.65 no.2
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• pp.113-120
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• 2022

We examined the anti-inflammatory properties of Nostoc commune HCW0811 in lipopolysaccharide-stimulated RAW264.7 macrophage cells. The anti-inflammatory activity of HCW0811 on viability of treated cells was assessed by measuring the level of expression of NO, prostaglandin E₂ and pro-inflammatory cytokines, namely interleukin-1β, interleukin-6, and tumor necrosis factor-α in HCW0811 treated RAW 264.7 macrophages. HCW0811 was non-toxic to cells and inhibited the production of cytokines in a concentration-dependent manner. In addition its treatment suppressed the production of pro-inflammatory cytokines in a dose-dependent manner, and concomitantly decreased the protein expressions of inducible NO synthase and cyclooxygenase-2. Moreover, the levels of the phosphorylation of mitogen-activated protein kinase family proteins such as extracellular signal-regulated kinase, c-Jun N-terminal kinase, p38, and nuclear factor kappa B were reduced by HCW0811. These findings suggest that the HCW0811 collected from Daejeon National Cemetery have anti-inflammatory effects, and demonstrated its efficacy in cell-based in vitro assays.

• Science of Emotion and Sensibility
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• v.25 no.1
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• pp.79-90
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• 2022

IThe perception of sub-second duration through the visual sensory system is affected by non-temporal characteristics (factors other than the duration of the stimulus). However, studies have shown that if distance information is abundant and size constancy maintained, the duration of the target is constantly perceived. The current study examined the relationship between size and time perception constancy in a three-dimensional environment with limited distance information. A device was constructed to limit the participants' bilateral and monocular cues. This prevented participants from maintaining size constancy, resulting in size illusions that could not accurately perceive physical size. In Experiment 1, the size of the physical stimulus of reference and test stimuli were the same at all viewing distances. The results suggest that, despite the same physical size, stimuli with close observations were perceived to be greater and lasted longer. In Experiment 2, the retinal size of the reference stimuli and test stimuli was controlled equally at all viewing distances. As a result, although the physical size of the stimuli increased as the observation increased, the perceived size of all the stimuli was the same. Therefore, the duration of the target was constantly perceived at all viewing distances. The results of this study demonstrate that even when distance information is limited, time perception is affected by the perceived size of the object. It also suggests that when rich distance information exists, the duration of the object can be constantly perceived even if the observation distance varies.

• Journal of Naturopathy
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• v.11 no.2
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• pp.136-142
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• 2022

Background: We are necessarily considering changes in the parasite infection rate and methods in Korea from 1970 to the present from the perspective of natural healing. Purposes: This study was to investigate how the difference in the rate of reduction in infection rate has changed and progressed to the present. Methods: A literature review was conducted. Results: Until the 1970s, Korea had one of the highest parasite infection rates. The Parasitic Disease Prevention Act was enacted to control the infection rate in 1966. From 1969, the nationwide national parasite management project was conducted for all students twice a year to treat all parasitic eggs until 1995. In addition, the government commissioned the Korean Association for Parasite Eradication (KAPE) to conduct a national parasite infection survey eight times, from 1971 to 2012, every two years. As a result, the overall egg positive rate of parasite was 84.3% in 1971 but decreased to 2.6% in 2012. In addition, Ascaris lumbricoides, Paragonimus westermani, Taenia spp., and intestinal protozoa were significantly reduced nationwide. Conclusions: Successful control in Korea is judged to have achieved a successful effect by systematically managing national economic growth, social consensus on parasite eradication, improved professional parasite prevention guidelines, and supply of effective anthelminthics.

• Journal of Naturopathy
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• v.9 no.2
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• pp.62-70
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• 2020

Purpose: According to the Body-EU education program, this study investigates changes after conducting education with ten subjects with autism symptoms (disability level 2~3) 63 times (126 hours) for nearly two years. Methods: Body-EU habit practice, note writings discussion, singing, Bible study, question and communication, class arrangement, etc., a total of 63 times were educated for 2 hours each week. Results: Subjects felt comfortable breathing and improved energy. Other subject's habit of an out-toed gait step and bending back alleviated. One subject made it easier to speak, so if talking with no strength. When breathing, the stuffy nose improved, the eyes became calm, and the hands and feet were warm. Subject felt like my head was cleaned. Heart tightness disappeared. Subject felt at ease as gaining confidence. The subject gained confidence in seeing whoever the other person was. The subject's pronunciation became more sophisticated, with more confidence, and his mouth cramping alleviated. Subjects with right eye movements showed a relatively high concentration in education time. Conclusions: Subjects are educated and trained in making general habits of their body from morning to going to bed. This study was a research program for ordinary people, but it confirmed with autism. Whether it was genetic autism or acquired autism, they could be somewhat relieved.

• Journal of Naturopathy
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• v.10 no.2
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• pp.114-119
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• 2021

Background: Many anionic phytoncides exist in the forest. Purpose: This study aimed to measure and investigate the number of negative ions in aerosol composition in Samdasu Forest, Jeju. Methods: We counted the number of negative ions in the aerosol with an anion meter at 17 points in the Samdasu forest area. Results: The average number of negative ions measured at 17 points in the aerosol of the Samdasu forest area was 719.7 ions/cm³, the temperature was 25.2℃, the humidity was 80.9%, the altitude was 503 m, and the wind speed was 0.6 m/sec. When looking at the content of anion number in the air quality in order, the highest place was waterfall-entrance-course R-course B- pine forest- course exit> exit wetland. The highest altitude of the collection point was in the order of pine forest-course R-course exit-waterfall-course B- exit wetland-entrance. The elevation difference in elevation was statistically significant. There was no correlation between altitude and anion content. It could be seen that the air quality fluctuates from time to time. Conclusions: A large amount of anionic phytoncide was contained in the air quality in Samdasu Forest in the over results. Therefore, Samdasu Forest is a helpful area as a place to visiting. The visit to the Jeju region, which has a high content of anionic phytoncide, has provided essential information that it has beneficial conditions for health management.

• Journal of Naturopathy
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• v.9 no.1
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• pp.27-32
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• 2020

Purpose: The purpose of this study was to investigate the changes in the autonomic nervous system of the human body after the use of ocher bedding radiating far-infrared rays to 15 insomnia subjects. Methods: Changes of autonomous nerve in the subjects after using loess bedding estimated by heart rate variability. Results: The mean HF before the use of ocher bedding was 220.8 msec², and the mean after use decreased to 5.1 msec². The average value of LF before use was 418.1 msec², and the mean after use decreased to 5.2 msec². The average before use of the VLF was 1463.3 msec², and the average after use dropped to 6.8 msec². The average value of TP before use was 977.3 msec², and the average after use dropped to 6.7 msec². The decrease in postoperative values of all four items was statistically significant, and the high value of the subjects before use inferred to be the reason that all of the subjects had high stress and anxiety due to their long-term sleep disorder. There was no significant difference in the pulses of the subjects before the use of the bedding. SDNN and RMSSD were not significantly different before and after use. Conclusions: Autonomic nerves HF, LF, VLF, TP frequency is evaluated to be affected by the investigation of far-infrared radiation that occurs ocher. This research data regarded as high value as primary data in this field.

• Journal of Naturopathy
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• v.11 no.1
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• pp.39-50
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• 2022

Background: It is essential to investigate the functionality of the newly developed knobble shoe. Purpose: The purpose was to explore how the body shape and balance change when wearing knobble shoes. Methods: Nine subjects wearing knobble shoes after walking for a month were analyzed. Results: For knobble shoes, we created various small air pockets in the insole to stimulate the soles of the feet to induce body changes. In particular, it was to promote the arch part of the foot by making a large lump inside and outside the center of the foot's arch. After wearing knobble shoes and using them for 30 days, the average blood sugar decreased by 31.1 mg. The lowering range was 5 to 120 mg. In one patient, the result of the hemoglobin test decreased by 7.5% to 6.5%. In the shoulder tapping test for a body balance test, seven subjects leaned to the right in a barefoot state, and two people to the left. However, after wearing shoes, all of them maintained equilibrium. knobble shoes fit, and balance was all stable. There were two subjects with a short left and four subjects with a short right. Conclusions: Blood sugar decreased after wearing the knobble shoes. The deformed shape of the body was restored to its original state by the knobble supporting the foot arch area. The balance of the sole directly affects the overall posture.

• Journal of Software Assessment and Valuation
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• v.16 no.2
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• pp.99-107
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• 2020

An underground integrated map is being built for underground safety management and is being updated periodically. The map update proceeds with the procedure of deleting all previously stored objects and saving newly entered objects. However, even unchanged objects are repeatedly stored, deleted, and stored. That causes the delay of the update time. In this study, in order to shorten the update time of the integrated map, an updated object and an unupdated object are separated, and only updated objects are reflected in the underground integrated map, and a system implementing this technology is described. For the updated object, an object comparison method using the center point of the object is used, and a quad tree is used to improve the search speed. The types of updated objects are classified into addition and deletion using the shape of the object, and change using its attributes. The proposed system consists of update object detection, extraction, conversion, storage, and history management modules. This system has the advantage of being able to update the integrated map about four times faster than the existing method based on the data used in the experiment, and has the advantage that it can be applied to both ground and underground facilities.