• Anxiety and mood
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• v.8 no.1
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• pp.22-30
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• 2012

Objective : We investigated whether Posttraumatic stress disorder patients have a higher tendency to exaggerate the extent of their psychological symptoms compared to other psychiatric patients. Methods : Medical records of patients, who had received psychiatric treatment at four university hospitals in Korea between January 2009 and December 2010, were retrospectively reviewed. We compared a group of 37 patients diagnosed with PTSD, and another group of 41 patients diagnosed with neurotic, stress-related and somatoform disorders according to the ICD-10. To compare the extent of malingering in the two groups, we compared the validity scales of MMPI-2 and Personality Assessment Inventory. We determined the number of participants in both groups feigning their responses by using various cutoff scores of the validity indicators. Results : The PTSD group showed significantly higher scores on the F (p=0.001), F (B)(p=0.000), F (P)(p=0.030), F-K (p=0.003) scale of the MMPI-2 compared to the other group of psychiatric patients. The PTSD group had a significantly higher NIM score (p=0.001) but a lower PIM score (p=0.020) of the PAI compared to the other group of psychiatric patients. Using the cutoff scores, the PTSD group showed a significantly higher number of patients who feigned responses compared to the other group ($Fb{\geq}75$ (p=0.010), $F-K{\geq}1$ (p=0.005), $F-K{\geq}10$ (p=0.011) from the MMPI-2, and $NIM{\geq}80$ (p=0.001) from the PAI). Conclusion : These results suggest that PTSD patients have a tendency to exaggerate their symptom. This group of patients overreported the severity of their condition during standardized personality assessment that included the MMPI-2 or PAI compared to patients diagnosed with other psychiatric disorders. Additional research is required to determine the factors influencing symptom exaggeration in PTSD.

• Journal of Korean Medicine Rehabilitation
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• v.29 no.2
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• pp.115-133
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• 2019

Objectives The purpose of this study was to evaluate the effects of Curcumae Longae Rhizoma pharmacopuncture on the monosodium iodoacetate (MIA)-induced osteoarthritis rats. Methods Osteoarthritis was induced by injection of MIA ($50{\mu}L$ with 80 mg/mL) into knee joint cavity of rats. Rats were divided into 6 groups. Normal group was injected by normal saline into knee joint cavity only. Control group was induced for osteoarthritis by MIA and orally administered with distilled water. Normal Saline group was induced for osteoarthritis by MIA and injected with normal saline $100{\mu}L$. Positive comparison group was injected with MIA and orally administered with indomethacin 5 mg/kg. Curcumae Longae Rhizoma pharmacopuncture low concentration (CL) group was induced for osteoarthritis by MIA and injected with Curcumae Longae Rhizoma pharmacopuncture low concentration $100{\mu}L$. Curcumae Longae Rhizoma pharmacopuncture high concentration (CH) group was induced for osteoarthritis by MIA and injected with Curcumae Longae Rhizoma pharmacopuncture high concentration $100{\mu}L$. Curcumae Longae Rhizoma pharmacopuncture was injected at ST35 and EX-LE4 each group (CL, CH). After that, hind paw weight distribution was measured and oxidative stress biomarker in serum, liver function biomarker in serum, western blot analysis were measured. Histological analysis of knee joint tissue was performed by hematoxylin and eosin staining, Safranin-O staining and Masson's trichrome staining. Results Hind paw weight distribution was significantly improved in both group. alanine aminotransferanse and aspartate aminotransferase were decreased significantly in CH group compare with Indomethacin threated group. Antioxidant enzyme glutathione peroxidase, Catalase and heme oxygenase-1 were increased in CH group compare with control group. Inflammatory cytokine cyclooxygenase-2, inducible nitric oxide synthase and interleukin-1 beta were decreased significantly in CH group. Histological analysis result shows that protective effects of joint and cartilage were observed in both CH and CL groups in a concentration-dependent. Conclusions The result suggest that Curcumae Longae Rhizoma pharmacopuncture has anti-oxidation effect, anti-inflammatory effect and also can prevent progression of osteoarthritis and protect joint cartilage.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.20 no.8
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• pp.133-138
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• 2019

This study evaluated the tensile properties of SAPH440, a hot-rolled steel for automotive structural applications, based on GMAW lap welding, the welding current, the welding voltage, and the feed rate. Tensile tests were performed according to the joint parameters of the GMAW process, for which specimens were fabricated according to KS B ISO 9018 by lap welding. The bead appearance was observed in each condition, and the weldability was evaluated by the tensile test. Higher the welding current resulted in a deeper weld, but the tensile strength was not significantly different from when the parameter was fixed due to the fracture of the base material. When the current was higher than the voltage, as in the case of a welding current of 200 A and welding voltage of 17 V, a large amount of spatter is generated, the welding is unstable, and the welded part breaks. Higher the voltage resulted in the bead not causing defects in general, and it also affected the weldability. If the current and voltage were too low, the welding was not performed normally, and the tensile strength could not be measured. However, as the current increased, the increase of the voltage and the feed rate did not affect the tensile strength.

• Mood & Emotion
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• v.16 no.3
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• pp.140-151
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• 2018

Objectives : The purpose of this study was to examine effects of adjunctive aripiprazole versus bupropion, on depressive symptoms of female depression. Methods : Sixty six female patients with major depressive disorders were enrolled from a six-week, randomized prospective open-label multi-center study. Participants were randomized to receive aripiprazole (2.5-10 mg/day) or bupropion (150-300 mg/day). Montgomery Asberg Depression Rating Scale, 17-item Hamilton Depression Rating scale (HAM-D17), Iowa Fatigue Scale, Drug-Induced Extrapyramidal Symptoms Scale, Psychotropic-Related Sexual Dysfunction Questionnaire scores, and Clinical Global Impression-Severity (CGI-S) were obtained at baseline and after one, two, four, and six weeks. Changes on individual items of HAM-D17 were assessed as well as on composite scales (anxiety, insomnia and drive), and on four core subscales that capture core depression symptoms. Results : Overall, both treatments improved depressive symptoms, without causing serious adverse events. There were significant differences in the HAM-D17 total score (p=0.046) and CGI-S (p=0.004), between aripiprazole and bupropion augmentation, favoring aripiprazole over bupropion. Aripiprazole revealed significantly greater effect size in depressed mood (p=0.006), retardation (p=0.005), anxiety psychic (p=0.032), and general somatic symptom (p=0.01). Conclusion : While both treatments were effective, results of this study suggested that aripiprazole may be preferable, in treating general and core symptoms of female depression.

• Journal of the Korea Society for Simulation
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• v.27 no.4
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• pp.61-68
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• 2018

This paper deals with ground clutter model for FOD (foreign object debris) surveillance FMCW (frequency modulated continuous waveform) radar. In the FOD surveillance radar, it has received not only the signals reflected by FOD, but also the clutters of the surface of the runway and the grassland simultaneously. However, to detect the FOD, the clutter rejection algorithm is necessary because the RCS (radar cross section) of FOD is nearly same to RCS of the grassland. In addition, it is difficult to apply the MTI (moving target indicator) algorithm as the clutter rejection algorithm because both the FOD and the clutter coexist stationarily. Hence, to remove the stationary clutter, it is crucial to accurately generate clutter map considering the surface of road. In this paper, in order to generate the clutter map, the respective beat signal at every range bin is generated in the case of only the surface without FOD, and then the beat signal accumulated 100 times. And also, Weibull distribution is applied to the RCS value to take the scattering distribution of clutter into consideration. The simulation results show that FOD can be well detected by applying the generated clutter map to the FOD FMCW radar.

• The Journal of The Korea Institute of Intelligent Transport Systems
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• v.17 no.6
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• pp.173-184
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• 2018

As the portable traffic information collection system using probe vehicles spreads, it is becoming possible to collect road hazard information such as portholes, falling objects, and road surface freezing using in-vehicle sensors in addition to existing traffic information. In this study, we developed a integration and decision algorithm that integrates time and space in real time when multiple probe vehicles detect events such as road hazard information based on GPS coordinates. The core function of the algorithm is to determine whether the road hazard information generated at a specific point is the same point from the result of detecting multiple GPS probes with different GPS coordinates, Generating the data, (3) continuously determining whether the generated event data is valid, and (4) ending the event when the road hazard situation ends. For this purpose, the road risk information collected by the probe vehicle was processed in real time to achieve the conditional probability, and the validity of the event was verified by continuously updating the road risk information collected by the probe vehicle. It is considered that the developed hybrid processing algorithm can be applied to probe-based traffic information collection and event information processing such as C-ITS and autonomous driving car in the future.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.20 no.9
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• pp.150-155
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• 2019

Cavitation refers to a phenomenon in which empty spaces occur in a fluid due to changes in pressure and a velocity. When a liquid moves at a high speed, the pressure drops below the vapor pressure, and vapor bubbles are generated in the liquid. This study used CFD to analyze the flow of fluid machinery used in marine and offshore plants. The goals are to ensure the validity of the analysis method for marine propellers in an open water test, to increase the forward ratio, and to use FLUENT to understand the flow pattern due to cavitation. A three-dimensional analysis was performed and compared with experimental data from MOERI. The efficiency was highest at advance ratios of 0.7 - 0.8. Thrust was generated due to the difference between the pressure surface and the suction surface, and it was estimated that bubbles would be generated in the vicinity of the back side surface rather than the face side of the propeller, resulting in more cavitation. The cavitation decreased sharply as the advance ratio increased. The thrust and torque coefficients were comparable to those of the MOERI experimental data except at the advance ratio of 1, which showed a difference of less than 5%. Therefore, it was confirmed that CFD can evaluate an open water propeller test.

• Asia-Pacific Journal of Business Venturing and Entrepreneurship
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• v.14 no.1
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• pp.33-46
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• 2019

Even though Korea is strengthening the support for startups due to the limitations of growth policies focusing on large companies, the survival rate of startups is very low, so that there should be more efforts to increase the survival rate of startups. As the existing startup support institutions have provided only fragmentary supports to startups, it would be necessary to have the comprehensive support institutions. As an alternative, the accelerator providing the comprehensive support such as spatial support, education, mentoring, networking, seed investment, and connection for follow-up investment to the initial startups was legalized in Korea of 2016, based on the registration system. Currently, within less than two year from then, there have been much interest in it enough to have about 136 registered accelerators. In the United States, the accelerator was introduced more than ten years ago. In Korea, however, it is still in the initial stage, so that the researches or social consensus on the accelerator are not sufficient. Thus, this study aims to suggest the measures for the development of accelerator and the consensus on the decision making for the selection of accelerator of startups, by researching which parts are considered when startups in the accelerator stage select the accelerator. As a result of the empirical analysis, the factor that has the greatest influence on decision making factors when startup chooses an accelerator was the subsequent investment attraction. This can be explained to the accelerator as desired, considering the factor that the startup of the initial stage places the most importance on growth as investment. We hope that these research results will be sustainable in future research related to accelerators, in hopes that it will be useful for establishing accelerator policies for domestic startups and direction for revitalizing related industries.

• Korean Journal of Food Science and Technology
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• v.53 no.1
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• pp.72-77
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• 2021

Silkworms have traditionally been used to produce silk and textiles. However, steamed and freeze-dried mature silkworm larval powder (SMSP) contain large amounts of amino acids, vitamins, and essential minerals. In this study, we investigated the potential of SMSP as a hangover-relieving agent. Thirty individuals who met the selection criteria and exclusion criteria were included in the study and subsequently underwent a double-blind, randomized, placebo-controlled, cross-design human application test. Importantly, the test product containing SMSP (CKDHC) was proven to alleviate hangovers through a significant reduction in the plasma concentration of acetaldehyde in the context of an alcohol-induced hangover model. In particular, from 0.5 h after SMSP intake, the blood acetaldehyde concentration (mg/L), area under the time curve (AUC; indicating the degree of bioabsorption of blood acetaldehyde), and the highest blood acetaldehyde concentration (Cmax) were reduced. Altogether, these results suggest that the test product (CKDHC) exhibits an accelerated hangover-relieving effect.

• Microbiology and Biotechnology Letters
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• v.49 no.2
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• pp.255-263
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• 2021

In this study, we assessed the technological characteristics and safety of 88 Enterococcus faecium strains isolated from meju; the strains possess the glutamate decarboxylase gene gadA/B involved in γ-aminobutyric acid production. The study was conducted to evaluate the possibility of introducing E. faecium meju isolates as food fermentation starters. We observed that a NaCl concentration of 6% (w/v) facilitated the growth and acid production of all strains. At a NaCl concentration of 7%, 21 strains (24%) exhibited a low growth rate, 72 strains (82%) a weak acid production, and 16 strains (18%) showed no acid production. All strains exhibited protease activity at a NaCl concentration of 4%. At a NaCl concentration of 5%, 86 strains exhibited weak activity, and one strain showed no protease activity. We could not detect any lipase activity in the investigated strains. None of the strains exhibited an acquired antibiotic resistance to the seven antibiotics tested in the present study, namely ampicillin, chloramphenicol, ciprofloxacin, gentamicin, penicillin G, tetracycline, and vancomycin. We could identify the Enterococcus endocarditis antigen gene efaA and the tyrosine decarboxylase gene tdc contributing to tyramine production, in 88 meju isolates. We could not detect the Enterococcus surface protein gene esp, which is specifically possessed by human-originated E. faecium strains, in any of the 88 strains tested in the study.