• Title/Summary/Keyword: 이종진

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Pattern of Drugs & Poisons in Autopsy Cases in Korea for Recent Three Years (2007~2009) - Selection of Target Drugs for Systematic Toxicological Analysis - (최근 3년간 국내 변사체 중 약독물 검출 유형(2007~2009) - 약독물 검출 시스템 확립을 위한 목표 약물의 선별 -)

  • Kim, Eun-Mi;Kim, Ji-Hyun;Hong, Hyo-Jeong;Jeong, Su-Jin;In, Sang-Hwan;Rhee, Jong-Sook;Jung, Jin-Mi;Lee, Han-Sun;Lee, Sang-Ki
    • YAKHAK HOEJI
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    • v.54 no.5
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    • pp.341-347
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    • 2010
  • The majority of forensic autopsies in Korea are performed by the National Institute of Scientific Investigation (NISI), and the NISI has carried out about 4,000 cases annually. Total 4,578 autopsies were performed by NISI in 2009, among them 2,918 cases (64%) were carried out at main office of NISI in Seoul, which is in charge of Seoul, Incheon and Gyeonggi province. In this study we investigated pattern of drugs & poisons in autopsy cases for recent three years in Korea. Postmortem specimens (bloods, gastric contents, etc) from autopsy cases by main office of NISI during 2007~2009 were screened for drugs & poisons. Using laboratory information management system of NISI (iLIMS), the kinds of drugs & poisons and the frequency were investigated. As the results, 1,705 cases were negative to drugs & poisons, it occupied 58% of total 2,918 autopsy cases in 2009. During three years (2007~2009), the kinds of drugs & poisons detected in specimens were 206, 185 and 203, respectively, and top three drugs were atropine (anticholinergic), chlorpheniramine (antihistamine) and lidocaine (local anaesthetic/anti-arrythmic). These drugs were supposed to be used not so much for suicidal or homicidal purpose as for therapeutic purpose in hospital. Meanwhile cyanide showed the highest frequency of poisons during 2007~2009, and the frequency was 32 cases in 2009. In case of pesticides, poisoning by paraquat (herbicide, 17 cases) showed the highest frequency, and methomyl (insecticide, 9 cases) and glyphosate (herbicide, 7 cases) were followed. Finally we selected 62 drugs as target drugs for systematic toxicological analysis (STA) for Korea. Poisons such as pesticides, natural toxins, volatile compounds should be included for STA in further study.

GPS/INS Integration and Preliminary Test of GPS/MEMS IMU for Real-time Aerial Monitoring System (실시간 공중 자료획득 시스템을 위한 GPS/MEMS IMU 센서 검증 및 GPS/INS 통합 알고리즘)

  • Lee, Won-Jin;Kwon, Jay-Hyoun;Lee, Jong-Ki;Han, Joong-Hee
    • Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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    • v.27 no.2
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    • pp.225-234
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    • 2009
  • Real-time Aerial Monitoring System (RAMS) is to perform the rapid mapping in an emergency situation so that the geoinformation such as orthophoto and/or Digital Elevation Model is constructed in near real time. In this system, the GPS/INS plays an very important role in providing the position as well as the attitude information. Therefore, in this study, the performance of an IMU sensor which is supposed to be installed on board the RAMS is evaluated. And the integration algorithm of GPS/INS are tested with simulated dataset to find out which is more appropriate in real time mapping. According to the static and kinematic results, the sensor shows the position error of 3$\sim$4m and 2$\sim$3m, respectively. Also, it was verified that the sensor performs better on the attitude when the magnetic field sensor are used in the Aerospace mode. In the comparison of EKF and UKF, the overall performances shows not much differences in straight as well as in curved trajectory. However, the calculation time in EKF was appeared about 25 times faster than that of UKF, thus EKF seems to be the better selection in RAMS.

Development of Permanent Displacement Model for Seismic Mountain Slope (지진 시 산사면의 영구변위 추정식 개발)

  • Lee, Jong-Hoo;Park, Duhee;Ahn, Jae-Kwang;Park, Inn-Joon
    • Journal of the Korean Geotechnical Society
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    • v.31 no.4
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    • pp.57-66
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    • 2015
  • Empirical seismic displacement equations based on the Newmark sliding block method are widely used to develop seismic landslide hazard map. Most proposed equations have been developed for embankments and landfills, and do not consider the dynamic response of sliding block. Therefore, they cannot be applied to Korean mountain slopes composed of thin, uniform soil-layer underlain by an inclined bedrock parallel to the slope. In this paper, a series of two-dimensional dynamic nonlinear finite difference analyses were performed to estimate the permanent seismic slope displacement. The seismic displacement of mountain slopes was calculated using the Newmark method and the equivalent acceleration time history. The calculated seismic displacements of the mountain slopes were compared to a widely used empirical displacement model. We show that the displacement prediction is significantly enhanced if the slope is modeled as a flexible sliding mass and the amplification characteristics are accounted for. Regression equation, which uses PGA, PGV, Arias intensity of the ground motion and the fundamental period of soil layer, is shown to provide a reliable estimate of the sliding displacement. Furthermore, the empirical equation is shown to reliably predict the hazard category.

Prevalence Rate and Etiologic Risk Factors of Atopic Dermatitis in the Preschool Children in Changwon (창원시 학동 전기 소아들의 아토피 피부염 유병률과 그 원인에 관한 연구)

  • Lee, Jong-Keun;Lee, Ho-Sung;Ha, Jin-Sil;Park, Dong-Jin;Paik, Do-Hyun;Ha, Kwon-Chul
    • Journal of Environmental Health Sciences
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    • v.35 no.3
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    • pp.169-177
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    • 2009
  • In the past decade there has been increasing concern about the atopic dermatitis (AD) associated with environmental diseases. AD has been increased in the last decade and known as one of the multifactoral diseases, which has the genetic background and environmental factors at the same time. The purposes of this study were to investigate the prevalence rate and etiologic risk factors of atopic dermatitis in preschool children in Changwon, which is a one of the Korean cities and has a large industrial complex. We reviewed and analyzed the statistical data, obtained from Korea National Health Insurance Corporation, related to prevalence rate by age and administrative district. A cross-sectional questionnaire survey, based on ISAAC (International Study of Allergy and Asthma in Childhood), was conducted on random samples of preschool children (5 to 8 years old) of large sized kindergartens in Changwon. The lifetime and last one years prevalence of AD in preschool children in Changwon was increased from 1998 to 2008. The prevalence rate of AD in the preschool children in Changwon city was 9.6%. The prevalence rate in boys was 9.7% and that in girls was 9.4%. The one year prevalence of AD was ranked as middle among other provincial cities in Korea in 2008. This study showed that the prevalence rate of the atopic disease in Changwon was 9% in 2008, which was increased especially compare to 2000. More active governmental approaches for control and prevention of atopic dermatitis for children are recommended. Further studies are needed for more accurate estimation of the prevalence of AD in Korea including different regional and age population.

Evaluating the Effectiveness of Work with the Remote System in PACS Room (PACS실에서 원격시스템을 이용한 업무의 효율성 평가)

  • Kim, Ji-Hye;Lee, Jong-Woong;Lee, Seung-Jin;Dong, Kyung-Rae
    • Korean Journal of Digital Imaging in Medicine
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    • v.13 no.4
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    • pp.171-175
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    • 2011
  • Server and Pi view management, external image and internal image Copy Import business in PACS room is through the medical assistance. Import and Copy, and in particular the number of cases is increasing the number of import is a fast growing trend. Although the increase in workload With limited human resources to increase business efficiency so Remote system is using PACS room. This remote system will want to evaluate the effectiveness of using the service. Amount of data each 437.5 MB, Copy and Import time is to compare and evaluate sees by use 1 PC. 4 PC, 4 PC+ remote system. The use of the remote system before the January 2010 to June daily average waiting time and the use of the remote system after the January 2011 to June compared to a daily average patient waiting time, evaluate. Using the remote system in January 2011 to June Find out the average remote utilization. The biggest difference on the four copy and eight continued, Were performed two times faster by use 4 PC+ remote system than use 4 PC and four times faster than use 1 PC. Before using the remote system, the daily average wait time is 14.5 minutes after using the daily average 10.2 minutes, waiting time 30% of the existing waiting time was 4.3 minutes, to reduce. Using the remote system in January 2011 to June the average daily number of cases is 107 number and The number of remote and on average 35 cases with 32% in a day remote usage. The use of the remote system to Import, CD Copy and greatly increase the efficiency of their time could be. Hours due to efficiency could also reduce customer waiting time. As a result, the manpower and the use of a remote system over time to maximize efficiency in business hours, work was evaluated by.

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Odor Characteristics of Essential Oil of Valeriana fauriei var. dasycarpa HARA (광릉쥐오줌풀의 정유향 특성)

  • Cho, Chang-Hwan;Lee, Jong-Chul;Kim, Young-Hoi;Kim, Kun-Soo;Ahn, Tae-Jin;Han, Ok-Kyu
    • Korean Journal of Medicinal Crop Science
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    • v.4 no.1
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    • pp.31-37
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    • 1996
  • This study was conducted to know the odor characteristics and compounds in neutral, acidic and basic fraction from the essential oil of Valerliana fauriei root. Among the fraction from the essential oil of V. fauriei root, the content of neutral fraction was 92%, that of the acidic fraction, 6%, and that of basic and phenolic fractions, less than 1%, respectively. The neutral fraction was characterized by sweet-balsamic, woody, musky and medicinal odor. The acidic fraction had sweat-socks, valeric-like and cheese-like odor characters. The netural fraction of essential oil was fractionated by solvents with different polarities, resulting in 44% of ethyl ether fraction, 34% of pentane-ethyl ether fraction, 11% of pentane fraction and 11% of methanol fraction. The ethyl ether fraction was characterized by woody and medicinal odor and the pentane-ethyl ether fraction, by sweet-balsamic, woody and herb-like odor. The fractions were fractionated again by different solvents, and 12 chemical components including valeranone, 26 components including bornyl acetate, and 43 components including camphene were identified in the ethyl ether fraction, the pentane - ethyl ether fraction, and pentane fraction, respectively. In the acidic fraction, n-butanoic acid and other 44 components were identified, among which the most abundant ones were 3-methyl butanoic acid(42.1%), dimethoxy-2-propanoic acid(11.5%), and 5-­ethyldihydro-2H-furanone(5.7%).

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The Study of Radon Activity and Uranium Concentration of Ground Water and Surface Water (지하수와 지표수에서의 라돈 및 우라늄의 실태 조사)

  • Oh, Youngmi;Lee, Jongbok;Shin, Kyungjin;Kim, Hakchul;Lee, Jaehee;Hwang, Sangchul;Jung, Sanggi;Lee, Sangtae
    • Journal of Korean Society on Water Environment
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    • v.23 no.2
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    • pp.201-205
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    • 2007
  • This paper reports the amount of $^{222}Rn$ and $^{238}U$ in 18 sites of ground water and 30 sites of surface water. The instrument used to count $^{222}Rn$ activity was the liquid scintillation counter (LSC) which could resolute ${\alpha}$ and ${\beta}$ radiations. And $^{238}U$ was analyzed by the inductively coupled plasma (ICP). Radon and Uranium were not detected in raw and treated water which were sampled in a water treatment plant. However, radon ($^{222}Rn$) was high concentration in ground water from Jeon-la, Gang-won. So was uranium ($^{238}U$) in case of ground water from Gang-won, Choong-chung. Radon ($^{222}Rn$) activities were detected less than 15 pCi/L at 5 sampling points, 15~300 pCi/L at 7 sampling points, 300~4000 pCi/L at 6 sampling points. However, Radon ($^{222}Rn$) activities of all ground water samples were less than 4,000 pCi/L, which was bellow American Alternative Maximum Contamination Level (AMCL). Uranium ($^{238}U$) concentrations were less than $0.1{\mu}g/L$ at 5 sampling points, from $0.1{\mu}g/L$ to $20{\mu}g/L$ at 13 sampling points. Uranium was not detected in about 30% of the whole samples, but the concentration ranged from relatively low to high concentrations depending on the sampling point. The minimum detectable activity (MDA) of radon was 15 pCi/L. and the detection limit of uranium was $0.1{\mu}g/L$.

Analysis of Genetic Diversity in Thirteen Turfgrass Cultivars Cultivated at Golf Courses Using RAPD Markers (RAPD마커를 이용한 국내골프장의 잔디 13 품종의 유전적 다양성 분석)

  • Kim, Min-Jeong;Kim, Tae-Soo;Shim, Chang-Ki;Kim, Yong-Ki;Jee, Hyeong-Jin
    • Weed & Turfgrass Science
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    • v.1 no.4
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    • pp.57-63
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    • 2012
  • This study was carried our to examine the genetic relationship of 13 commercial turfgrass cultivars using Random Amplified Polymorphic DNA to provide genetic informations more efficient golf course management. Analysis of 56 random hexamer primers generated 13 to 54 polymorphic bands among the 13 cultivars with an average of 30.7 bands per primer. The results of cluster analysis based on RAPDs revealed that three major variety groups: Group I - 'Shadow II', 'Aurora Gold', 'Little Bighorn Blue', 'PennA-1', and 'PennA-4'; Group II - 'Midnight II', 'Prosperity', 'Moon light SLT', 'Bright star SLT', and 'Silver dollar'; and Group III - 'Olympic Gold', 'Silver Star', and 'Tar Heel II'. The genetic similarity coefficients among 13 turfgrass cultivars ranged from 0.039 to 1.0 with highest coefficient in Group III. Studies on morphological characters and the effective molecular markers such as sequence characterized amplified regions are further needed to identify relationships and genetic diversities within species and among species.

Temporary Threshold Shift of Vibration Sensation by Dental Handpiece (치과용 핸드피스에 의한 일시적 진동감각역치 변화)

  • Kim, Seong-Ah;Lee, Jong-Young;Kim, Doo-Hie;Park, Soon-Woo
    • Journal of Preventive Medicine and Public Health
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    • v.28 no.4 s.51
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    • pp.765-771
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    • 1995
  • This study was performed to investigate the possibility of temporary threshold shift (TTS) of vibration sense could induced by exposure to high-frequency vibration or by work position taking by dentists in drilling or polishing. The vibratory perception thresholds (VPT) of 28 healthy men were measured on the index fingertip pulp of dominant hand at 250 Hz. The vibrating tool used in test was a low-speed handpiece of 34,000 rpm. For the TTS test, the dominant hand was exposed to high-frequency vibration and to work position for five minutes, respectively. The VPTs before and after vibratory exposure were $23.5{\pm}3.5dB,\;30.8{\pm}4.2dB$, respectively and VPT after work position was $23.7{\pm}4.6dB$. The difference between before and after vibartory exposure was statistically significant (p<0.001). The correlation of height, weight and BMI with baseline VPTs was not statistically significant. Also, there was no difference of VPTs by smoking. These results suggest that high-frequency vibration from dental handpieces might cause the impairment of vibration sensation.

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The Effects of Diesel Exhaust Particulates and Particulate Matters on the ICAM-1 and VCAM-1 Expression in the Lung of Asthma-incuced Mouse (디젤분진 및 미세분진이 천식마우스의 폐조직에서 ICAM-1과 VCAM-1의 발현에 미치는 효과)

  • Li, Tian-Zhu;Lee, Soo-Jin;Jang, Yang-Ho;Lee, Jeong-Hak;Park, Se-Jong;Park, Jun-Hong;Chang, Byung-Joon;Lee, Jong-Hwan;Choe, Nong-Hoon
    • Journal of Life Science
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    • v.17 no.3 s.83
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    • pp.396-401
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    • 2007
  • This research investigated whether exposure of diesel exhaust particulate (DEP) and particulate metter (PM) effect on intercellular. adhesion molecule-1 (ICAM-1) and vascular cell adhesion molecule-1 (VCAM-1) expression in asthma-induced Balb/c and IL-10 knock out (KO) mouse. Mouse was sensitized with intraperitoneal injection with ovalbumin, followed by challenges with intranasal ovalbumin. After induction of asthma mouse placed in the inhalation chamber and exposed to DEP and PM (10 $mg/m^3$). The evidences of pulmonary inflammation were assessed by immunohistochemical stain and westen blot against ICAM-1 and VCAM-1 in the lung tissue. In the immunohistochemical stain, positive reactions for ICAM-1 and VCAM-1 were much stronger in asthma-induced groups and asthma-induced group with DEP or PM than control groups. Although mild positive reactions were appeared in asthma-induced IL-10 KO mice groups, positive reactions were very strong in the asthma-induced group with DEP or PM. In Western blot, expression of VCAM-1 was increased in asthma-induced group with DEP or PM than asthma-induced groups. In the IL-10 KO mouse, ICAM-1 and VCAM-1 expression were increased in asthma-induced group with DEP or PM than asthma-induced groups. DEP and PM exposure have additive effects on the aggravation of inflammatory signs in the asthma-induced murine model. These results suggest that inhalation of DEP and PM in asthmatic patients may aggravate clinical symptoms.