• Title/Summary/Keyword: 이원진

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LIPID PEROXIDATION AND ANTIOXIDANTS IN WORMERS EXPOSED TO LEAD (연 폭로 근로자들의 지질과산화 및 항산화상태에 관한 연구)

  • Lee, Won-Jin;Hwang, Cheon-Hyun;Kim, Cheong-Sik;Chang, Soung-Hoon;Kim, Yang-Ho;Kim, Hae-Joon
    • Journal of Preventive Medicine and Public Health
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    • v.31 no.3 s.62
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    • pp.449-459
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    • 1998
  • This study was started to find out if plasma malondialdehyde(MDA), $\alpha-tocopherol$ and erythrocyte superoxide dismutase(SOD) activity could be markers of biological activity resulting from exposed to lead in workers. Blood samples were randomly obtained from lead-exposed workers(n=29), $CO_2$, welders(n=60) and office workers(n=60). We used whole blood to analyse blood lead with atomic absorption spectrophotometer. Superoxide dismutase activity in erythrocyte was measured with spetrophotometer. MDA and $\alpha-tocopherol$ in plasma were measured with high performance liquid chromatography. Lead-exposed workers was significantly high in blood lead concentration$(29.37{\mu}g/d\ell)$ compared with welders$(6.42{\mu}g/d\ell)$ and office workers$(5.01{\mu}g/d\ell)$. The level of plasma MDA was significantly higher in the lead-exposed workers($1.87{\mu}mol/g$ cholesterol) than the welders($1.41{\mu}mol/g$ cholesterol) and office workers($1.41{\mu}mol/g$ cholesterol). Erythrocyte SOD activity in lead-exposed workers(56.80 U/g Hb) was significantly increased than those of welders(37.63 U/g Hb) and office workers(20.47 U/g Hb). The plasma $\alpha-tocopherol$ level of lead-exposed workers($4.93{\mu}g/g$ cholesterol) was statistically different from welders($4.25{\mu}g/g$ cholesterol) and office workers$4.28{\mu}g/g$ cholesterol). Neither age nor smoking was related to SOD or MDA level. Blood lead was significantly correlated with erythrocyte SOD activity(r=0.405), plasma MDA(r=0.296) and $\alpha-tocopherol$ (r=0.207). Plasma MDA was also significantly correlated with SOD (r=0.217). In multiple regression analysis, the change of MDA and SOD activity level related to the blood lead concentration. These results suggested that the increase of plasma MDA and erythrocyte SOD activity in lead-exposed workers had a close relationship with the oxidative stress induced by lead.

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Localized Pneumoconiosis Manifested by Solitary Pulmonary Nodule Mimicking Lung Cancer -One case report- (폐암으로 의심되는 고립성 폐결절로 발현된 국한성의 진폐증 - 1례 보고 -)

  • 이기복;박희철;홍기우;이원진;김건일;최광민;김태윤;안혜경
    • Journal of Chest Surgery
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    • v.35 no.8
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    • pp.611-615
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    • 2002
  • Pneumoconiosis is fibrogenic disease, caused by inhalation of mineral dust. It is defined as the accumulation of dust in the lung and tissue reaction to its presence and the dust is considered to be an aerosal of solid and inanimate particles. It is among the most common and the most important occupational lung disease, especially in developing countries. It is required three prerequisites for making a clinical diagnosis of pneumoconiosis: 1) a full clinical and occupational history together with the result of physical examination; 2) previous X-ray for comparison; and 3) a clear understanding of the time scale involved in the progression of the diseases. Most pneumoconiosises are slow to evolve and changes in the appearances take many months -usually years- to occur. Pneumoconiosis is represented on a plain X-ray of the chest as multiple small round opacities, usually smaller than 1cm diameter. In 58 years old female patient, pneumoconiosis is manifested as $5{\times}4{\times}3$cm sized solitary pulmonary nodule without any occupational history and past history of exposure of dust. so we treated this case with right upper lobectomy. Therefore we report this case with a brief review of literatures.

Periosteal Ewing's Sarcoma of the Rib (늑골 막에 생긴 골 외 유잉 육종)

  • Shin, Dong-Il;Kim, Jung-Tae;Chang, Woon-Ha;Oh, Tae-Yoon;Lee, Won-Jin;Bang, Yun-Yi
    • Journal of Chest Surgery
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    • v.42 no.3
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    • pp.404-407
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    • 2009
  • A 43-yr-old patient visited our department with intermittent chest pain he had suffered with for the past 2 months. Chest CT showed an egg shaped mass in the left chest wall. Local resection was performed for distinguishing the mass from a neurogenic tumor. The diagnosis was periosteal Ewing sarcoma of the rib. Since there was no evidence of metastasis based on the PET-CT, a 2nd operation was done with wide resection and thoracoplasty. The patient was then treated with combined chemotherapy. There has been no local recurrence for the fast 1 year. The patient's age and tumor origin were distinct from the usual characteristics of Ewing's sarcoma. Periosteal Ewing's sarcoma of the rib has rarely been reported. We report here on a case of periosteal Ewing's sarcoma of the rib along with a review of the relevant medical literature.

The Effects of Planned Discharge Nursing in Compliance, Knowledge, and Nursing Service Satisfaction for Patients having Video-Assisted Thoracoscopic Surgery (계획된 퇴원 간호 중재가 기흉 수술 환자의 약물복용 및 치료 지시 이행도, 질병에 대한 지식과 간호 만족도에 미치는 효과)

  • Lee, Won Jin;Bang, Yun Yi
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.20 no.11
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    • pp.121-129
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    • 2019
  • This study aimed to develop a planned discharge nursing intervention guideline for patients with pneumothorax, and to examine its influence on drug compliance, knowledge about disease, compliance level with therapeutic regimen, and nursing satisfaction. Methods: The planned discharge nursing intervention guideline was developed based on comprehensive literature reviews and clinical experiences. Patients having video-assisted thoracoscopic surgery at a single general hospital were allocated to either intervention (n=30) or control group (n=29). Participants in the intervention group were administered planned discharge nursing intervention thrice, 30 minutes each, by a cardiovascular nurse. Standard care was provided to patients in the control group. Data were collected from March, 2010 to December, 2010. Results: Participants in the intervention group presented statistically significant improvement in drug compliance (t=-2.05, p=0.044), pill count (t=-2.61, p=0.011), knowledge about disease (t=-4.39, p=0.001), and nursing satisfaction (t=-4.13, p=0.001). No significant difference in compliance levels was observed with standard therapeutic regimen. Conclusion: Planned discharge nursing intervention can be successfully implemented for patients undergoing thoracoscopic surgery. Further research is required to evaluate long-term effects like complication or relapse.

Two-dimensional Velocity Measurements of Uvêrsbreen Glacier in Svalbard Using TerraSAR-X Offset Tracking Approach (TerraSAR-X 위성레이더 오프셋 트래킹 기법을 활용한 스발바르 Uvêrsbreen 빙하의 2차원 속도)

  • Baek, Won-Kyung;Jung, Hyung-Sup;Chae, Sung-Ho;Lee, Won-Jin
    • Korean Journal of Remote Sensing
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    • v.34 no.3
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    • pp.495-506
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    • 2018
  • Global interest in climate change and sea level rise has led to active research on the velocities of glaciers. In studies about the velocity of glaciers, in-situ measurements can obtain the most accurate data but have limitations to acquire periodical or long-term data. Offset tracking using SAR is actively being used as an alternative of in-situ measurements. Offset tracking has a limitation in that the accuracy of observation is lower than that of other observational techniques, but it has been improved by recent studies. Recent studies in the $Uv{\hat{e}}rsbreen$ glacier area have shown that glacier altitudes decrease at a rate of 1.5 m/year. The glacier displacement velocities in this region are heavily influenced by climate change and can be important in monitoring and forecasting long-term climate change. However, there are few concrete examples of research in this area. In this study, we applied the improved offset tracking method to observe the two-dimensional velocity in the $Uv{\hat{e}}rsbreen$ glacier. As a result, it was confirmed that the glacier moved at a maximum rate of 133.7 m/year. The measruement precisions for azimuth and line-of-sight directions were 5.4 and 3.3 m/year respectively. These results will be utilized to study long-term changes in elevation of glaciers and to study environmental impacts due to climate change.

Reliability of Self-Reported Information by Farmers on Pesticide Use (일부 농업인에서 자기 기입식 농약 노출 설문에 대한 신뢰도 연구)

  • Lee, Yo-Han;Cha, Eun-Shil;Moon, Eun-Kyeong;Kong, Kyoung-Ae;Koh, Sang-Baek;Lee, Yun-Keun;Lee, Won-Jin
    • Journal of Preventive Medicine and Public Health
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    • v.43 no.6
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    • pp.535-542
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    • 2010
  • Objectives: Exposure assessment is a major challenge faced by studies that evaluate the association between pesticide exposure and adverse health outcomes. The objective of this study was to investigate the reliability of information that farmers self-report regarding their pesticide use. Methods: Twenty five items based upon existing questionnaires were designed to focus on pesticide exposure. In 2009, a selfadministrated survey was conducted on two occasions four weeks apart among 205 farmers residing in Gyeonggi and Gangwon provinces. For a reliability measure, we calculated the percentage agreement, the kappa statistics and the intraclass correlation coefficient (ICC) between the two reports according to the characteristics of the subjects. Results: Agreement for ever-never use of any pesticide was 96.4% (kappa 0.61). For both 'years used' and 'age at the first use' of overall pesticides, high agreement was obtained (ICC: 0.88 and, 0.78, respectively), whereas those of 'days used' and 'hours used' were relatively low (ICC: 0.42 and, 0.66, respectively). The kappa value for the use of personal protective equipment ranged from 0.46 to 0.59, and hygiene activities came out at 0.19 to 0.37. The agreement for individual pesticide use ranged widely and there was relatively low agreement due to the low response rates. The reliability scores did not significantly vary according to gender, age, the education level, the types of crop or the years of farming. Conclusions: Our results support that carefully designed, self-reported information on ever-never pesticide use among farmers is reliable. However, the reliability of data on individual pesticide exposure may be unstable due to low response rates and needs to be refined.

Relation of the radiologic findings and labeling index of Ki-67, PCNA and cytokeratin in unicystic ameloblastoma, dentigerous cyst and odontogenic keratocyst (낭성법랑모세포종, 함치성낭, 치성각화낭의 방사선소견과 Ki-67, PCNA, Cytokeratin 발현과의 연관성에 관한 연구)

  • Song Man-Yong;Lee Sam-Sun;Lee Jin-Koo;Lee Won-Jin;Heo Min-Suk;Lee Jae-Il;Min Byung-Moo;Choi Soon-Chul
    • Imaging Science in Dentistry
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    • v.34 no.2
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    • pp.75-79
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    • 2004
  • Purpose: To compare the proliferation potential of the epithelial cells between unicystic ameloblastoma (UA), dentigerous cyst (DC), and odontogenic keratocyst (OKC) and to correlate this proliferation potential with the radiographic features of these three pathoses. Materials and Methods: Immunohistochemical expression of PCNA, Ki-67, and cytokeratin as a proliferation marker were assessed for 15 cases of UA, 15 cases of DC, and 15 cases of OKC. The degree of immunochemical expression of three proliferation markers were correlated with the radiographic features, especially cortical expansion (negative and positive) and shape of border (scalloped and round). Results: Using PCNA and Ki-67, OKC showed the highest proliferation potential and UA the lowest. Statistically significant differences were found between the OKC and the UA (p < 0.05). However, no statistically significant difference was present according to the radiographic features in all pathoses. Using cytokeratin, there was no significant differences of proliferation potential among three pathoses. Conclusions : OKC epithelium has the most intense proliferation potential, followed by the dentigeous cyst and then unicystic ameloblastoma. There is no significant relation between the radiographic features and the proliferation potential of epithelium of these three pathoses.

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A study of the panoramic radiographic images of the buccolingual dilaceration (협설만곡치아의 파노라마방사선영상소견에 대한 연구)

  • Kim, Young-Ho;Jeong, Hwan-Seok;Huh, Kyung-Hoe;Yi, Won-Jin;Heo, Min-Suk;Lee, Sam-Sun;Choi, Soon-Chul
    • Imaging Science in Dentistry
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    • v.40 no.1
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    • pp.39-44
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    • 2010
  • Purpose : We want to identify the appearance of the buccolingual root dilaceration teeth in the panoramic views and specify the characteristics of these teeth. Materials and Methods : One thousand-six patients were examined on the basis of both panoramic and CT image criteria. We diagnosed and excluded certain teeth from the samples; both prosthodontic or pathologic lesion appearing teeth and mesiodistally dilacerated ones. We meticulously discerned buccolingually dilacerated teeth in the CT images and total 48 samples were selected. The degree of severity in dilaceration was standardized by 2 types of criteria. The samples were differentiated into 3 groups and again categorized into six types showing from the panoramic views: irregular view on the root apex area, clear blunt on the root tip, stepping on root tip, double lamina dura or double tip, arrow-target shaped root, bull's eye, normal view. Results : The types of teeth selected from total 48 buccolingual root dilaceration samples were mandibular first and second molar, premolars, canines, and lateral incisors. The direction of dilaceration was an even percentage to each buccal and lingual side for most selected teeth, however, that of both canines and lateral incisors were directed in almost a buccal side. In the panoramic views, the root types of the buccolingually dilacerated teeth were irregular view on the root apex area, clear blunt on the root tip, stepping on root tip and normal types were almost always normal view. The more severity in dilareated degree, the more chances of observation in the panoramic views were clear blunt on the root tip and stepping on root tip. Conclusion : As observed in the shape of stepping on root tip or double lamina dura in the panoramic views, there can be much more probability to diagnose as a buccolingually dilacerated root.

Usefullness of panoramic radiograph for the improvement of periodic oral examination (구강검진의 효과 증진을 위한 파노라마방사선사진의 필요성에 관한 연구)

  • Shin, Min-Jung;Choi, Bo-Ram;Huh, Kyung-Hoe;Yi, Won-Jin;Heo, Min-Suk;Lee, Sam-Sun;Choi, Soon-Chul
    • Imaging Science in Dentistry
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    • v.40 no.1
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    • pp.25-32
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    • 2010
  • Purpose : This study was designed to evaluate the efficacy and utility of panoramic radiograph for the improvement of the periodic oral examinations. Materials and Methods : Clinical examinations and panoramic examinations were done for the 242 subjects of oral examinations. The results of panoramic radiograph interpretation were compared with the clinical findings. Two questionnaires were created. One was carried out before the panoramic examination and the other done afterwards, to find out the subjects' cognition and satisfaction for the clinical and panoramic examinations. Results : 1. Panoramic findings showed a higher detection rate of 31.9% for periodontal diseases, and 23.1% for dental caries than clinical findings. 2. The additional abnormalities detected through panoramic examinations were impacted tooth in 81 subjects (33.6%), maxillary sinus abnormalities in 28 subjects (11.6%), condylar abnormalities in 5 subjects (2.1%), congenital and acquired dental anormalies in 59 subjects (24.5%), and other miscellaneous abnormalities in 34 subjects (14.1%). 3. 164 subjects (67.8%) were satisfied with the current periodic oral examination, and 75 subjects (31.1%) hoped for better accuracy. 4. In the first and second questionnaire, 154 subjects (67.0%) and 163 subjects (70.6%) responded respectively that panoramic examination was necessary, and 193 subjects (83.2%) responded that it actually helped. Conclusion : The panoramic examination was revealed to improve the effectiveness of the periodic oral examination and to increase the satisfaction of the subjects of examination.

Nerve Conduction Velocity among Farmers Exposed to Pesticides (일부 농약 폭로 농민들의 신경전도 검사에 관한 연구)

  • Lee, Won-Jin;Choi, Jin-Yong;Lee, Kun-Sei
    • Journal of agricultural medicine and community health
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    • v.24 no.1
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    • pp.1-11
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    • 1999
  • This study was carried out to find out if peripheral neuropathy was resulting from exposed to pesticides in farmers. Thirty four male farmers in rural area of Chungju were selected as a study group. According to the farm type and area, the group was subdivided into two groups: the high exposed group(n=20) and the low exposed group(n=14). Nerve conduction velocity tests were done on four nerves of the dominant arm(median motor, median sensory, ulnar sensory, and ulnar motor) and three nerves of the dominant leg(peroneal motor, sural sensory, and posterior tibial motor). On the nerve conduction study, all of the results were included normal range. But comparing to reference mean values, most of results were significantly decreased(P < 0.01 by t-test). And the median motor conduction velocity and the peroneal nerve latency were significantly increased in the high exposed group than the low exposed group and reference values. But we concluded that these findings are caused by age difference not pesticide exposure. In conclusion, we cannot find any abnormality of nerve conduction velocity caused by exposure to pesticide in this study group.

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