• Title/Summary/Keyword: 이용성 평가

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Design and Economic Analysis of Low Pressure Liquid Air Production Process using LNG cold energy (LNG 냉열을 활용한 저압 액화 공기 생산 공정 설계 및 경제성 평가)

  • Mun, Haneul;Jung, Geonho;Lee, Inkyu
    • Korean Chemical Engineering Research
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    • v.59 no.3
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    • pp.345-358
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    • 2021
  • This study focuses on the development of the liquid air production process that uses LNG (liquefied natural gas) cold energy which usually wasted during the regasification stage. The liquid air can be transported to the LNG exporter, and it can be utilized as the cold source to replace certain amount of refrigerant for the natural gas liquefaction. Therefore, the condition of the liquid air has to satisfy the available pressure of LNG storage tank. To satisfy pressure constraint of the membrane type LNG tank, proposed process is designed to produce liquid air at 1.3bar. In proposed process, the air is precooled by heat exchange with LNG and subcooled by nitrogen refrigeration cycle. When the amount of transported liquid air is as large as the capacity of the LNG carrier, it could be economical in terms of the transportation cost. In addition, larger liquid air can give more cold energy that can be used in natural gas liquefaction plant. To analyze the effect of the liquid air production amount, under the same LNG supply condition, the proposed process is simulated under 3 different air flow rate: 0.50 kg/s, 0.75 kg/s, 1.00 kg/s, correspond to Case1, Case2, and Case3, respectively. Each case was analyzed thermodynamically and economically. It shows a tendency that the more liquid air production, the more energy demanded per same mass of product as Case3 is 0.18kWh higher than Base case. In consequence the production cost per 1 kg liquid air in Case3 was $0.0172 higher. However, as liquid air production increases, the transportation cost per 1 kg liquid air has reduced by $0.0395. In terms of overall cost, Case 3 confirmed that liquid air can be produced and transported with $0.0223 less per kilogram than Base case.

Evaluation of the Potential of Cellobiose as a Material for Whitening Cosmetics based on Autophagy and Melanin Production Efficacy in Melanocytes (셀로비오스의 미백화장품 소재 가능성 평가를 위한 멜라닌 세포에서 자가포식 및 멜라닌 생성 효능 연구)

  • Byungsun, Cha;Seok ju, Lee;Sofia, Brito;So Young, Jung;So Min, Lee;Lei, Lei;Sang Hun, Lee;Zubaidah, Al-Khafaji;Bum-Ho, Bin;Byeong-Mun, Kwak;Hyojin, Heo
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.48 no.4
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    • pp.365-372
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    • 2022
  • Cellobiose is a dissacharide constituted by two glucose units joined by a β-('1,4') glycosidic bond that is produced by the decomposition of cellulose. This product exists naturally in plants and has been utilized in different industries as a food sweetener, and as a cosmetic and pharmaceutical material. In this study, the potential of cellobiose as a whitening cosmetic product was evaluated by analyzing autophagy induction and the inhibition of melanin production. A cytotoxicity test conducted in the human melanin-producing cell line MNT-1 with increasing concentrations of cellobiose revealed that this compound did not cause cytotoxicity at 20 mg/mL or less. Based on this, autophagy was firstly evaluated by immunostaining with the autophagy marker microtubule-associated protein 1 light chain 3 (LC3) after treatment with 20 mg/mL of cellobiose. The subsequent confocal microscopy analysis revealed an increase in LC3 puncta, indicating induction of autophagy. In addition, autophagy was further confirmed by western blot analysis, which demonstrated that cellobiose converted LC3-I to LC3- ∏ in a concentration- and time-dependent manners. An analysis of melanin contents after cellobiose treatment at a concentration of 20 mg/mL during 7 days revealed that melanin production was reduced by more than 50%. Additionally, the expression levels of melanogenesis-related proteins TYR and TYRP1 were markedly decreased after cellobiose treatment. Based on these studies, a cosmetic cream formulation containing cellobiose was prepared and the change in formulation was tested for 4 weeks, and it was confirmed that the appearance changed to liquid form at high temperature, but the pH did not change. In conclusion, the present research demonstrated that cellobiose activates autophagy and inhibits melanin production, and showed the potential of this product as a material for whitening cosmetics.

Antioxidative Effects of Tenebrio molitor Larvae Extract Against Oxidative Stress in ARPE-19 Cells (ARPE-19 세포에서 산화적 스트레스에 대한 갈색거저리 추출물의 항산화 효과)

  • Bong Sun, Kim;Ra-Yeong, Choi;Eu-Jin, Ban;Joon Ha, Lee;In-Woo, Kim;Minchul, Seo
    • Journal of Life Science
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    • v.32 no.11
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    • pp.865-871
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    • 2022
  • Tenebrio molitor larvae is well known as edible insect. Then, although it has been widely studied that Tenebrio molitor larvae has various bioactive functions such as antioxidant, anti-wrinkle, and anticancer. Nevertheless, antioxidant effects of Tenebrio molitor larvae water extract (TMH) has not been well described in Adult Retina Pigment Epithelial cell line (ARPE-19). In this study, we demonstrated that antioxidant effects of TMH against H2O2-induced oxidative stress in ARPE-19. Thus, we selected for our studies and performed a series of dose-response assay to determine the working concentration that lead to a consistent and high degree of cytotoxicity, which we defined as the level of H2O2 that killed 40% of the ARPE-19 cells. ARPE-19 cells were pre-treated with various concentrations of TMH (0.1 up to 2 mg/ml) before exposure to 300 µM H2O2. As we expected, TMH effectively prevented ARPE-19 cells from 300 µM H2O2-induced cell death in a dose-dependent manner. Furthermore, TMH inhibited the phosphorylation of mitogen-activated protein kinases (MAPKs) such as extracellular signal regulated kinase (ERK), c-Jun N-terminal kinase (JNK), and p38. Overall, the inhibitory effects of TMH on H2O2-induced apoptosis and oxidative stress were associated with the protection cleaved caspase-3, Bax, Bcl-2, and HO-1. The TMH suppressed H2O2-induced cell membrane leakage and oxidative stress in ARPE-19 cells. Thus, these results suggest that the TMH plays an important role in antioxidant effect in ARPE-19.

Prediction of Acer pictum subsp. mono Distribution using Bioclimatic Predictor Based on SSP Scenario Detailed Data (SSP 시나리오 상세화 자료 기반 생태기후지수를 활용한 고로쇠나무 분포 예측)

  • Kim, Whee-Moon;Kim, Chaeyoung;Cho, Jaepil;Hur, Jina;Song, Wonkyong
    • Ecology and Resilient Infrastructure
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    • v.9 no.3
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    • pp.163-173
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    • 2022
  • Climate change is a key factor that greatly influences changes in the biological seasons and geographical distribution of species. In the ecological field, the BioClimatic predictor (BioClim), which is most related to the physiological characteristics of organisms, is used for vulnerability assessment. However, BioClim values are not provided other than the future period climate average values for each GCM for the Shared Socio-economic Pathways (SSPs) scenario. In this study, BioClim data suitable for domestic conditions was produced using 1 km resolution SSPs scenario detailed data produced by Rural Development Administration, and based on the data, a species distribution model was applied to mainly grow in southern, Gyeongsangbuk-do, Gangwon-do and humid regions. Appropriate habitat distributions were predicted every 30 years for the base years (1981 - 2010) and future years (2011 - 2100) of the Acer pictum subsp. mono. Acer pictum subsp. mono appearance data were collected from a total of 819 points through the national natural environment survey data. In order to improve the performance of the MaxEnt model, the parameters of the model (LQH-1.5) were optimized, and 7 detailed biolicm indices and 5 topographical indices were applied to the MaxEnt model. Drainage, Annual Precipitation (Bio12), and Slope significantly contributed to the distribution of Acer pictum subsp. mono in Korea. As a result of reflecting the growth characteristics that favor moist and fertile soil, the influence of climatic factors was not significant. Accordingly, in the base year, the suitable habitat for a high level of Acer pictum subsp. mono is 3.41% of the area of Korea, and in the near future (2011 - 2040) and far future (2071 - 2100), SSP1-2.6 accounts for 0.01% and 0.02%, gradually decreasing. However, in SSP5-8.5, it was 0.01% and 0.72%, respectively, showing a tendency to decrease in the near future compared to the base year, but to gradually increase toward the far future. This study confirms the future distribution of vegetation that is more easily adapted to climate change, and has significance as a basic study that can be used for future forest restoration of climate change-adapted species.

Comparative Analysis of Antioxidant, Anti Aging and Phenolic Compounds of Different Solvent Extracts from Saccharina japonica and Costaria costata (추출용매에 따른 쇠미역과 다시마의 항산화, 항노화 활성과 페놀화합물 비교분석)

  • Hyun-Hwa Lee;Jin-Sol Kim;Jun-Han Jeong;Chun Sung Kim;Sook Young Lee
    • Korean Journal of Plant Resources
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    • v.36 no.2
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    • pp.107-121
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    • 2023
  • This study analyzed the polyphenol, flavonoid contents, antioxidant activity, anti-aging activity and phenol component contents of Saccharina japonica (SJ), Costaria costata (CC) extracts with hot water, 95% methanol, 95% prethanol for investigating possible utilization of SJ and CC extracts. The result revealed that the SJ and CC methanol extracts showed the highest polyphenol and flavonoid contents, 4.63 mg TAN/g, and 4.19 mg QUE/g respectively. Also, the SJ and CC methanol extracts showed higher antioxidant activity than prethanol and hot water extracts, whereas the ABTS radical scavenging activities were the highest in prethanol extracts (IC50 = 15.4, 10.3 ㎍/µL). In anti-aging activity for evaluating the anti-wrinkle activity and skin whitening activity, the CC methanol extracts had high collagenase inhibitory activity (88.3%), and the SJ prethanol extracts showed higher elastase inhibitory activity (19.0%) compared to other extracts. Then the tyrosinase inhibitory activity was significantly higher in the SJ and CC methanol extracts (41.8, 30.3%, respectively), whereas prethanol extracts were the lowest. To identify the phenol component contents of SJ and CC extracts, 4-hydroxybenzoic acid, naringenin, naringin and nicotinic acid were measured using LC-MS/MS. As a result, the phenol contents were the highest in SJ methanol extract (4-hydroxybenzoic acid), SJ and CC prethanol extract (naringin and naringenin) and CC prethanol extract (nicotinic acid). Lastly, the antioxidant activity of SJ and CC showed high correlations with polyphenol and flavonoid contents (R = -0.946~0.883). These results suggest that prethanol or methanol extracts of SJ and CC have higher antioxidant activities, anti-aging activity and the potential to be used as material for health functional food and cosmetics.

Antioxidant and Antiwrinkle Effects of Persimmon Leaves extract (시엽(Persimmon Leaves) 에탄올 추출물의 항산화와 항주름 효과)

  • Sung-Hee Kim;Dong-Hee Kim;Wi-Hye Yeon;Jin-Tae Lee;Young-Ah Jang
    • Journal of the Korean Applied Science and Technology
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    • v.40 no.3
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    • pp.534-546
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    • 2023
  • In this study, we investigated the antioxidant and anti-winkle activity in human fibroblast cell (CCD-986sk) of Persimmon Leaves (PL) as a cosmetic ingredient. As a result of investigating antioxidant activity through electron-donating ability and ABTS+ radical scavenging assay, the PL showed concentration-dependent antioxidant activity similar to ascorbic acid, a control group, at a concentration of 1,000 ㎍/ml. As a result of investigating the anti-wrinkle effect through elastase inhibition and collagenase inhibition assay, the PL showed concentration-dependent antioxidant activity similar to epigallocatechin gallate, a control group, at a concentration of 1,000 ㎍/ml. As a result of measuring the synthesis rate of pro-collagen type I and the inhibition rate of MMP-1 in UVB-induced CCD-986sk cells, the control group EGCG showed a 90.2% pro-collagen synthesis rate at 20 ㎍/ml and PL showed an 88.5% synthesis rate at 30 ㎍/ml. In addition, the inhibition rate of MMP-1 of 33.0% and 40.8% were confirmed in EGCG 20 ㎍/ml and PL 30 ㎍/ml, respectively. As a result of measuring the protein expression of pro-collagen type I and MMP-1 in the PL through western blot, it was confirmed that the protein expression of pro-collagen type I increased, and MMP-1 decreased when the PL was treated together compared to the UVB alone group. According to the above experimental results, it is expected to be used as a natural product material for cosmetics by confirming that the PL prevent photoaging caused by UVB stimulation and have antioxidant and anti-wrinkle effects.

Analysis of Spatial Changes in the Forest Landscape of the Upper Reaches of Guem River Dam Basin according to Land Cover Change (토지피복변화에 따른 금강 상류 댐 유역 산림 경관의 구조적 변화 분석)

  • Kyeong-Tae Kim;Hyun-Jung Lee;Whee-Moon Kim;Won-Kyong Song
    • Korean Journal of Environment and Ecology
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    • v.37 no.4
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    • pp.289-301
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    • 2023
  • Forests within watersheds are essential in maintaining ecosystems and are the central infrastructure for constructing an ecological network system. However, due to indiscriminate development projects carried out over past decades, forest fragmentation and land use changes have accelerated, and their original functions have been lost. Since a forest's structural pattern directly impacts ecological processes and functions in understanding forest ecosystems, identifying and analyzing change patterns is essential. Therefore, this study analyzed structural changes in the forest landscape according to the time-series land cover changes using the FRAGSTATS model for the dam watershed of the Geum River upstream. Land cover changes in the dam watershed of the Geum River upstream through land cover change detection showed an increase of 33.12 square kilometers (0.62%) of forests and 67.26 square kilometers (1.26%) of urbanized dry areas and a decrease of 148.25 square kilometers (2.79%) in agricultural areas from the 1980s to the 2010s. The results of no-sampling forest landscape analysis within the watershed indicated landscape percentage (PLAND), area-weighted proximity index (CONTIG_AM), average central area (CORE_MN), and adjacency index (PLADJ) increased, and the number of patches (NP), landscape shape index (LSI), and cohesion index (COHESION) decreased. Identification of structural change patterns through a moving window analysis showed the forest landscape in Sangju City, Gyeongsangbuk Province, Boeun County in Chungcheongbuk Province, and Jinan Province in Jeollabuk Province was relatively well preserved, but fragmentation was ongoing at the border between Okcheon County in Chungcheongbuk Province, Yeongdong and Geumsan Counties in Chungcheongnam Province, and the forest landscape in areas adjacent to Muju and Jangsu Counties in Jeollabuk Province. The results indicate that it is necessary to establish afforestation projects for fragmented areas when preparing a future regional forest management strategy. This study derived areas where fragmentation of forest landscapes is expected and the results may be used as basic data for assessing the health of watershed forests and establishing management plans.

A Study on How Urban Gardening Affect Citizens' Quality of Life and Social Capital in Deteriorated Neighborhood - Focus on the Residential Complex in Gojan 1-Dong, An San City - (노후 근린생활권 정원 활동이 지역 주민의 삶의 만족과 커뮤니티에 미치는 영향 연구 - 경기도 안산시 고잔1동 연립주택단지를 대상으로 -)

  • Park, Ji-eun;Sung, Jong-Sang;Son, Yong-Hoon
    • Journal of the Korean Institute of Landscape Architecture
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    • v.51 no.1
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    • pp.56-71
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    • 2023
  • Citizens' needs for urban green spaces are on the rise due to improved quality of life and increased interest in environments. The garden is noteworthy because it is small in size, making it less controversial to create in the city, and it is adjacent to the residential area, improving citizens' daily environment. Moreover, recently gardens is attracting attention as a tool for urban regeneration, such as being created in declining areas as part of a government project. Therefore, it is time to study the role and value of urban gardens in deteriorated areas in terms of space welfare. However, there are few studies that quantitatively evaluate the effects of gardens, and many prior studies are limited to focusing the green space larger than a certain size (e.g., parks and forests). Therefore, the aim of this study is to examine the effect of garden and gardening quantitatively, paying attention to social aspects such as life satisfaction and community of inhabitants. The study was conducted in an old row housing complex in Gojan1-dong, Ansan-si, Gyeonggi-do. In there, some of the dwellers voluntarily created outdoor gardens and engaged in gardening for a long time. In addition, after the 2017 Gyeonggi-do Garden Fair, several gardens have been maintained and used by residents there. For the first step, the field trip was done to research the status of the garden in the area, and then, a survey was conducted on whether or not gardening has an impact on the life satisfaction and community of residents. The results were analyzed by t-test and ANOVA. As a result, residents who are engaged in gardening are more active in the "neighborhood exchange" and "resident participation" than those who are not engaged in gardening. In addition, if residents voluntarily create a garden, the level of "satisfaction of life" is higher than those staying in the garden which is constructed by the government. And a resident who is gardening in the complex shows higher life satisfaction than those who garden outside of the complex. These results confirmed that the garden has positive effects promoting "exchanges with neighbors", "participation in the community", and "life satisfaction" of residents. It shows that it is important to ensure the right of residents to participate in the garden-making process as much as possible, and the garden's location should be paid attention to maximize the positive effect of gardens.

Fish Community Structures and Distribution Characteristics of Fisheries Resources in the Osip Stream and Wangpi Stream, Fishery Resources Protection Areas (내수면 수산자원보호구역 오십천 및 왕피천의 어류군집 구조 및 수산자원 분포특성)

  • Kyung-hoon Kim;Jin-wang Lee;Young-bin Jo;Jae-Hyun Lim;Ji-Woong Choi
    • Korean Journal of Ecology and Environment
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    • v.56 no.1
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    • pp.57-69
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    • 2023
  • The objectives of this study were to analyze the fish community structures and distribution characteristics of fisheries resources in the Osip Stream and Wangpi Stream, fishery resources protection areas. For the study, we conducted fish samplings four times in the two streams from April to October 2019. In Osip Stream and Wangpi Stream, we sampled 31 species and 29 species and the dominant species were Zacco platypus (28.6%) and Squalidus multimaculatus(41.7%), respectively. According to the life type of fish species, primary freshwater species were collected 18 species(58.1%) and 21 species(72.4%), and migration fishes were sampled 4 species (12.9%) and 6 species (20.7%) in Osip Stream and Wangpi Stream, respectively. Fisheries resources species showed high relative abundance in June, and the fish biomass was highest in October. As a results of comparing the previous studies with this study, both rivers showed high biodiversity and were found to maintain stable populations of fishes. According to analysis of tolerance guilds, the proportion of tolerant species, based on the number of individuals, was composed of 14.4% and 1.1% in Osip Stream and Wangpi Stream, respectively. This very low ratio of tolerant species confirmed that both streams have very good physiochemical environment conditions. From the above results, it was judged that the fishery resource protection areas of Osip Stream and Wangpi Stream have high ecological function and preservation value. For sustainable use and management of fishery resource protection areas of Osip Stream and Wangpi Stream, it is suggested that biological disturbance management, fish discharge projects considering environmental capacity, efforts to improve the habitat environment, and establishing a fishery resource protection areas management system were necessary as considerations.

Promotion effects of steam-dried Betula platyphylla extract on hair regrowth (자작나무 증포 추출물의 발모 촉진 효과)

  • Ahn, Jeong Won;Jang, Su Kil;Jo, Bo Ram;Kim, Hyun Soo;Jeoung, Eui Young;Hillary, Kithenya;Yoo, Yeong Min;Joo, Seong Soo
    • Korean Journal of Food Science and Technology
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    • v.54 no.1
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    • pp.43-51
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    • 2022
  • Regulation of the hair follicle cycle in association with dermal papilla cells is one of the most interesting targets for promoting hair regrowth. In this study, we examined whether steam-dried Betula platyphylla extracts (BPE) promote hair growth by upregulating in vitro and in vivo responses of dermal papilla cells. The data showed that BPE3 contained high amounts of phenolic compounds with higher antioxidant effects and increased hair growth-related genes, including fibroblast growth factor7 and Wnt7b, in dermal papilla cells. Notably, BPE3 effectively enhanced the formation of hair follicles by increasing FGF7, Wnt7b, and vascular endothelial growth factor in C57BL/6N dorsal skins. Additionally, BPE3 significantly decreased the expression of inflammatory repertoires, inducible nitric oxide synthase, interleukin-6, and cyclooxygenase 2. Several small molecules, such as betulin and unsaturated fatty acids, support the pharmacological activity of BPE3. In conclusion, BPE3 effectively promoted hair growth by activating dermal papilla cells and enhancing hair follicle cycles by attenuating the inflammatory environment in the scalp.