• Journal of Korean Society for Geospatial Information Science
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• v.12 no.4 s.31
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• pp.21-26
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• 2004

Annually repeated flood damage is bringing about the rapid increasement of the loss of human lives and properly, and the enormous social cost for the restoration work is required. The annual amount of flood damage caused by the abnormal climate is reached about 1% of GDP, so more effective management of the flood control operation is needed to prevent the repetitive flood occurred same region. Also, the systematic planning and management or river improvement works are keenly required for the more effective execution of government working budget that expense to recover or to prevent the flood damage. The several organizations of government - Ministry of Construction & Transportation, Ministry of Government Administration and Home Affair, Ministry of Agriculture and Forestry, Ministry of Environment, Ministry of Science & Technology, Korea Meteorological Adminstration and so on - are promoting the flood prevention operations, but those promotion system makes it difficult to maintain the consistency of works. In this study, we try to develop the Web-GIS system prototype that will be able to effectively manage the nationwide river improvement works and to establish a framework that will be able to maintain the consistency of river improvement works. To achieve the study goals, we analysed current system of flood prevention operations, gathered related documents, had interviews with many government employees, and developed the Web-GIS system prototype.

• Journal of Korea Water Resources Association
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• v.43 no.5
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• pp.495-505
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• 2010

The integrated basin-wide flood mitigation planning has a numerous individual proposals with different characteristics. So, it makes difficult to develop the optimal alternative that combines such elements. To develop the optimal alternative, it's necessary not only to assess the flood damage but also to define a tolerable degree of damage. Such a definition is made in a way, dubbed the 'social consensus' in a broad sense; but initially, it requires the analysis of the economic efficiency within a scope, which is technically achievable. This study aims to propose the alternatives development method so that the combination of the individual proposals could be economically efficient. To this end, this study defined the flood mitigation projects as the economic production activities carried out by inputs and outputs, and proposed the optimal project size as the principle of developing alternatives. This study may have the worth in improving the alternatives development method by considering the optimal project scale from the economic viewpoint while the existing method depending on engineering aspect. Such approach is expected to correspond to the current government's policy that avoids the passive flood mitigation focused on channel-wide planning but pursues the basin-wide flood mitigation planning focusing on damaged area, thereby provide efficient tools to come up with the solution.

• Journal of Korea Water Resources Association
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• v.47 no.4
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• pp.343-356
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• 2014

The SWMM (storm water management model) has been widely used in the world and is a watershed runoff simulation model used for a single event or a continuous simulation of runoff quantity and quality. However, there are many uncertain parameters in the watershed runoff continuous simulation module and the water quality module, which make it difficult to use the SWMM. The purpose of the study is to develop an automatic calibration module of the SWMM not only for watershed runoff continuous simulation, but also water quality simulation. The automatic calibration module was developed by linking the SWMM with the SCE-UA (shuffled complex evolution-University of Arizona) that is a global optimization algorithm. Estimation parameters of the SWMM were selected and search ranges of them were reasonably configured. The module was validated by calibration and verification of the watershed runoff continuous simulation model and the water quality model for the Donghyang Stage Station Basin. The calibration results for watershed runoff continuous simulation model were excellent and those for water quality simulation model were generally satisfactory. The module could be used in various studies and designs for watershed runoff and water quality analyses.

• Journal of Korea Water Resources Association
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• v.47 no.8
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• pp.671-684
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• 2014

Change point analysis is a efficient tool to understand the fundamental information in hydro-meteorological data such as rainfall, discharge, temperature etc. Especially, this fundamental information to change points to future rainfall data identified by reasonable detection skills can affect the prediction of flood and drought occurrence because well detected change points provide a key to resolve the non-stationary or inhomogeneous problem by climate change. Therefore, in this study, the comparative study to assess the performance of the 3 change point detection skills, cumulative sum (CUSUM) method, Bayesian change point (BCP) method, and segmentation by dynamic programming (DP) was performed. After assessment of the performance of the proposed detection skills using the 3 types of the synthetic series, the 2 reasonable detection skills were applied to the observed and future rainfall data at the 5 rainfall gauges in South Korea. Finally, it was suggested that BCP (with 0.9 posterior probability) could be best detection skill and DP could be reasonably recommended through the comparative study. Also it was suggested that BCP (with 0.9 posterior probability) and DP detection skills to find some change points could be reasonable at the North-eastern part in South Korea. In future, the results in this study can be efficiently used to resolve the non-stationary problems in hydrological modeling considering inhomogeneity or nonstationarity.

• Journal of Korea Water Resources Association
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• v.53 no.4
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• pp.313-322
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• 2020

There is always a risk of water disasters due to sudden storms in mountainous regions in Korea, which is more than 70% of the country's land. In this study, a radar-based risk prediction technique for sudden downpour is applied in the mountainous region and is evaluated for its applicability using Mt. Biseul rain radar. Eight local heavy rain events in mountain regions are selected and the information was calculated such as early detection of cumulonimbus convective cells, automatic detection of convective cells, and risk index of detected convective cells using the three-dimensional radar reflectivity, rainfall intensity, and doppler wind speed. As a result, it was possible to confirm the initial detection timing and location of convective cells that may develop as a localized heavy rain, and the magnitude and location of the risk determined according to whether or not vortices were generated. In particular, it was confirmed that the ground rain gauge network has limitations in detecting heavy rains that develop locally in a narrow area. Besides, it is possible to secure a time of at least 10 minutes to a maximum of 65 minutes until the maximum rainfall intensity occurs at the time of obtaining the risk information. Therefore, it would be useful as information to prevent flash flooding disaster and marooned accidents caused by heavy rain in the mountainous area using this technique.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• v.26 no.4
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• pp.337-344
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• 2000

Germ-line mutations at DNA repair loci confer susceptibility to colon cancer in hereditary non-polypopsis colorectal cancer. Somatic loss of DNA mismatch repair gene has been reported in a large variety of other tumor types. Replication errors(RERs) judged by microsatellite instability(MSI) and its associated mutations have been recognized as an important mechanism in various tumor types. To investigate associations between MSI and oral squamous cell carcinoma, the frequency of MSI using 12 microsatellite markers were analyzed for the series of oral tumors. Of 17 tumors, 8 cases(47%) did not show instability at any of the 12 loci; 5(29%) showed instability at $2{\sim}3$ loci; and 4(24%) showed instability above 4 loci. The 4 cases showing widespread MSI did not differ from those without evidence of instability in terms of age at diagnosis, degree of differentiation, metastasis to lymph node, tumor location or the presence of mutations in the p53 tumor suppressor gene. DCC and D17S 796 were the most frequently detected in MSI analysis. There were no correlation between smoking and MSI frequency, instead, smoking was suggested to increase the mutation rate of p53 and development of oral carcinomas.

• Journal of Digital Convergence
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• v.15 no.6
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• pp.315-327
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• 2017

This study was carried out to examine the converging factors related to academic burnout in students from health-related majors who are involved in studying for the Test of English for International Communication (TOEIC). Research subjects included 291 randomly selected students from the J-region, who were enrolled in TOEIC classes. Data collection took place from April 3, 2017 to April 14, 2017, using anonymous self-administered questionnaires. The results of a multiple regression analysis in female students showed higher academic burnout pertaining to studying for the TOEIC when sleeping hours, self-worth, self-efficacy, school adaptation resilience, and study immersion were low, and job-seeking stress and test anxiety were high. The explanatory power of this model was 65%. Based on these results, to reduce academic burnout pertaining to studying for the TOEIC in health majors, it is first necessary to increase sleeping hours, self-worth, self-efficacy, school adaptation resilience, and study immersion, and to make efforts to manage self-competence, job-seeking stress, and test anxiety. The results of this study may be used to decrease the academic burnout caused by studying for the TOEIC in health major students and to increase their aptitude for studying English, to cultivate globalized capabilities. Future studies need to conduct an effect analysis on the control and mediation effect that these factors have on academic burnout.

• Journal of the Korean Society of Food Science and Nutrition
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• v.41 no.12
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• pp.1747-1752
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• 2012

This study investigated the physiochemical characteristics of Xanthoceras sorbifolia seed oil. Xanthoceras sorbifolia seed oil was extracted by supercritical fluid extraction (420 atm, $50^{\circ}C$), hexane extraction and heat-pressed extraction ($160^{\circ}C$, $180^{\circ}C$). Acid values and peroxide values were evaluated, as well as the degree of lipid oxidation. The heat-pressed ($160^{\circ}C$) extraction gave a $53.5{\pm}2.5%$ higher yield of oil, compared with the other extraction methods. The acid values from the super critical fluid extraction were the highest, while peroxide values were highest from the heat-pressed extraction at $160^{\circ}C$ (3.10 meq/kg). The contents of linolenic acid and oleic acid were 38.63~41.13% and 26.29~26.85%, respectively. Contents of stigmasterol and ${\beta}$-sitosterol were 6.01~6.49 mg/100 g and 58.19~59.85 mg/100 g, respectively. These results indicate that Xanthoceras sorbifolia seed oil can possibly serve as new edible oils.

• Journal of the Korean Institute of Landscape Architecture
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• v.42 no.3
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• pp.76-89
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• 2014

The functions of urban park including health related benefit and climate adaptation and mitigation are expanding. However, in-depth research and discourse on the equitable distribution of expanded park function has been limited so far. Following research suggests Green Welfare concept to reflect distributive equity and multifunctionality in the process of urban park policy development and execution. This study developed park welfare indices to analyze disparities of neighborhood urban park(NUP) distribution viewed from green welfare by literature review. The findings analyzed through the Correlation Analysis and Cluster Analysis by SPSS 18.0. The results of the study are as follows. First, green welfare is defined as "to receive equitable benefits and participate in the delivery process of green services which are promoting health and securing safety from climate change risks for every citizen by life cycle regardless of socioeconomic status". Second, NUP per person in Seoul indicate meaningful differences by socioeconomic and environmental status of Seoul administrative districts. Park welfare indices correlated to NUP per person were shown population density(negative), percentage of individuals $aged{\geq}65$(positive), percentage of self-reliance of local finance(positive), flood and air pollution vulnerability by climate change(negative). Third, the cluster analysis identifies three significant clusters that indicate differences of park welfare level. Thus, it was found that NUP in Seoul from a green welfare perspective was provided disproportionately. Future urban park policy in Seoul was required equitable distribution of multifunctionality of park beyond quantitative expansion, and priority consideration should be given to park service consumer.

• Journal of Life Science
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• v.25 no.11
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• pp.1235-1243
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• 2015

Hwangheuk-san (HHS) is a Korean multi-herb formula comprising four medicinal herbs. HHS, which was recorded in “Dongeuibogam,” has been used to treat patients with inflammation syndromes and digestive tract cancer for hundreds of years. However, little is known about its anti-tumor efficacy. The present study investigated the pro-apoptotic effect and mode of action of HHS against AGS human gastric carcinoma cells. HHS inhibited the cell growth of AGS cells in a dose-dependent manner, which was associated with the induction of apoptotic cell death, as evidenced by the formation of apoptotic bodies, chromatin condensation, and an accumulation of cells in the sub-G1 phase. HHS-induced apoptotic cell death was associated with the up-regulation of pro-apoptotic Bax protein expression, down-regulation of antiapoptotic Bcl-2 protein, and the release of cytochrome c from mitochondria to the cytosol. The treatment of AGS cells with HHS significantly elevated the generation of reactive oxygen species (ROS). Additionally, apoptosis-inducing concentrations of HHS induced the activation of both caspase-9 and -8, initiator caspases of the mitochondrial-mediated intrinsic and death receptor-mediated extrinsic pathways, respectively, and caspase-3, accompanied by proteolytic degradation of poly (ADP-ribose)-polymerase. However, ROS scavenger and pan-caspases inhibitor significantly blocked HHS-induced growth inhibition and apoptosis. Taken together, these findings suggest that HHS induces apoptosis through ROS- and caspase-dependent mechanisms and that HHS may be a potential chemotherapeutic agent for the control of human gastric cancer.