• Proceedings of the Korea Society for Industrial Systems Conference
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• 2000.11a
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• pp.493-503
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• 2000

인터넷은 "정보의 바다"라는 말처럼 날마다 방대한 양의 데이터가 쏟아져 나오고 있으며, 이런 방대한 데이터 속에서 정보를 찾기란 쉽지 않다. 그러나 인터넷 사용자들은 정확한 정보를 신속하게 언제 어디서나 획득할 수 있기를 희망한다. 현재 정보의 창고인 도서관은 더 이상의 Paper 정보가 아닌 Digital 정보로의 변화가 필요하며 각 분야에서 많은 연구가 이루어지고 있다. 연구개발정보센터(KORDIC)에서는 과학기술지역인프라 구축사업을 통해서 광주ㆍ전남권역을 시범 권역으로 선정하여 13개 대학의 도서관, 산업단지, 연구소(KORDIC)를 하나로 묶는 즉, 산ㆍ학ㆍ연이 하나가 되어 상호대차 원문 서비스를 할 수 있도록 기반을 구축하는데 목적이 두고있다. 본 시스템은 상호대차 원문 서비스를 위해 대학 간 분담수서를 통해서 분담된 도서를 원문서비스 하는 상호 협력 체제를 구축하는데 필요한 시스템이며 사용자들은 해외 저널 원문을 신청하게되고, 서비스 담당자는 신청된 해외저널원문을 Digital화해서 사용자에게 보내주는 체제를 구축하기 위해 열악한 대학에는 시스템과 통신 인프라를 지원하여 상호대차원문서비스가 가능하게 하는 것을 전제로 하고 있다. 분담수서를 통해 서비스하게 될 해외저널에 대해서는 각 대학에서 책임감을 가지고 서비스를 해야하므로 서비스의 질과 업무의 자립도를 높일 수 있으며 상호대차를 통해 산ㆍ학ㆍ연이 하나처럼 연계가 된다. 또한 해외 학술 저널 DB를 공동으로 구축하여 국내 지역별 대학소장 해외 학술 전문자료를 데이터베이스화, 전문정보망을 구축 회원기관 간 정보교류의 활성화, 대학 소장 해외 학술 전문자료의 정보 표준화 효과를 창출할 수 있으며, 분담수서를 통해 얻어지는 예산 절감으로 새로운 분야에 재투자한다면 정보의 질적, 양적 향상을 도모하게 될 것이다.것으로 나타났다.본 규격은 키, 총장, 어깨길이, 등길이, 머리길이, 머리둘레, 진동둘레, 목둘레, 가슴둘레, 허리둘레, 배둘레, 엉덩이둘레, 앞품, 뒤품, drop치를 포함하고 있고, 각 규격에서 호칭간 치수 간격도 함께 제시하고 있다. 본 연구 결과에서 보듯, 현행 8규격의 무진복의 각 호칭간 적정 허용범위를 고려해 합리적인 치수체계를 정립한다면 치수에 대한 적합도가 상당히 증가할 뿐 아니라 생산비용도 상당히 감축할 것으로 생각된다.나타났다. 4) 호감적 서비스능력 차원에서 세 독립변수간에 유의한 3원 상호작용이 존재하는 것으로 나타나( $F_{2,228}$=15.62, P<.001) 20대에 적합한 의복 착용시( $F_{2,228}$=3.98, P<.05)와 60대에 적합한 의복 착용시( $F_{2,228}$=16.55, P<.001) 점포유형과 격식차림간에는 유의한 상호작용이 존재하는 것으로 나타났다. 5) 호감을 구성하는 세 요인들이 구매의도에 미치는 영향을 조사한 결과 호감적 인상차원은 29%(P<.001), 호감적 서비스능력차원은 6%(P<.001)의 구매의도를 설명해 주는 것으로 나타났다. 본 연구결과 노년 소비자에게 호감을 주는 판매원의 외모는 구매의도에 영향을 주어 실버의류산업의 이익증대와 밀접한 연관을 갖는 서비스품질의 중요한 요인으로 밝혀졌다.중요한 요인으로 밝혀졌다.로운 단백질 EPSPS가 다른 여러 식물에 이미 존재하고 있는 단백질로서 우리가 이미 이러한 식품을 섭취할 때 이 단백질도 같이 섭취해오고 있었다는 점, 둘째. 이 단백질이 소화액 분해 실험에서 짧은 시간내에 분해가 되었다는 점, 셋째. 재조합 된 콩과 자연 콩이 성분 분석에서 차이를 나타내지 않았다는 점, 네 번째. 쥐를 통한 다양섭취

• Journal of Physiology & Pathology in Korean Medicine
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• v.25 no.4
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• pp.669-673
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• 2011

To prevent and treat the osteoporotic fracture, more attention should be paid in old age patients. Osteoclast which has ability to bone resorption is originated from hematopoietic cell line and plays a key role osteoporotic bone loss. Rubi Fructus has been widely used in Oriental medicine. Extracts of the leaves and fruit of Rubus species have been used in various countries as natural remedies to treat diabetes, infections, colic, and burns. However, the effect of extract of Rubi Fructus (fruit of Rubus coreanus Miq.) in osteoclast differentiation remains unknown. Thus, we evaluated the effect of Rubi Fructus on receptor activator of nuclear factor-kB ligand (RANKL)-induced osteoclast differentiation. Here we found that Rubi Fructus significantly inhibited osteoclast differentiation induced by RANKL. Rubi Fructus suppressed the activation of p38 pathway and NFkB in bone marrow macrophages (BMMs) treated with RANKL. Also, Rubi Fructus significantly inhibited the mRNA expression of c-Fos, tartrate-resistant acid phosphatase (TRAP), osteoclast-associated receptor (OSCAR), nuclear factor of activated T cells (NFAT)c1 and cathepsin K in BMMs treated with RANKL. Particularly, Rubi Fructus greatly inhibited the protein expression of c-fos and NFATc1. especially in the case of NFATc1 expression, a master transcription factor of the differentiation of osteoclasts is very important step for osteoclastogenesis. Taken together, our results demonstrated that Rubi Fructus may be useful treatment option of bone-related disease such as osteoporosis and rheumatoid arthritis.

• Korean Journal of Veterinary Research
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• v.52 no.2
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• pp.125-131
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• 2012

Rabbit hemorrhagic disease is a highly acute and fatal viral disease caused by rabbit hemorrhagic disease virus (RHDV). Since first outbreak in Korea 1987, RHDV has been continually affected in the country, but the pattern of outbreak seem to be changed. In this study, to understand the pathogenesis of the new RHDVa serotype, we therefore carried out to inoculate RHDVa to rabbits, and to examine the sequential histopathologic changes and viral distribution. Macroscopically, various sized dark red or white spots or appearance were observed in the liver, lung, kidney uterus and ureter. In euhanized rabbits, significant pathologic findings such as infiltration of heterophils and mononuclear cells were observed at 24 hours after inoculation (HAI), and these were sequentially extended periportal to centrilobular area. However, in dead rabbits, severe hepatic degeneration and/or necrosis with relatively weak inflammatory responses were observed. RHDV antigens began to detect in liver, spleen, and lung from 12 HAI by PCR. Immunohistochemically, RHDV positive cells were seen in only liver from 24 HAI, and the degree of immunogen reactivity was stronger in dead rabbits than in euthanized ones. In conclusion, RHDVa caused the subacute or chronic infection accompanying low mortality and moderate to severe inflammatory reaction in rabbits, suggesting the possibility that RHD could become endemic.

• Korean Journal of Microbiology
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• v.48 no.3
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• pp.175-179
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• 2012

Adenoviruses are an important cause of respiratory tract infections, particularly in infants, young children, and immuno-compromised patients. In this study, we investigated the characteristics of adenoviruses isolated from outpatients with acute respiratory illness in Gyeonggi province of South Korea during 2009-2011. Adenoviruses were detected in 102 of 1,622 (6.3%) specimens by using PCR or real-time PCR with viral specific primers. 76 isolates were obtained from 102 specimens using the A549 cells. Serotypic distributions of isolated adenovirus were analyzed by sequencing of hexon gene. Six different serotypes were identified, which included adenovirus serotypes 1-6. Adenovirus 3 (n=40, 52.6%) was the predominant serotype. The predominant types of adenovirus every year were serotypes 1 and 3 in 2009, serotype 3 in 2010, and serotype 5 in 2011, respectively. Adenoviruses 1, 2, 4, 5, and 6 were isolated sporadically throughout the study period. Adenovirus 3 was present both during outbreaks and in sporadic cases. These results indicate that adenovirus 3 played major causative agent of adenovirus outbreaks in Gyeonggi province of South Korea during 2009-2011. Continuous surveillance for specific serotypes of adenovirus that can cause outbreaks is important.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.56 no.3
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• pp.205-211
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• 2011

This study was carried out to find optimum roasting condition of sesame seeds for making seed season and oil treated with different temperatures and time intervals. Sesame seeds with 17~18% of moisture content were treated under fixed and changed roasting temperature conditions. The fixed temperatures are ranged from 160 to $240^{\circ}C$ with $20^{\circ}C$ intervals. The changed temperatures were treated at low(160 and $180^{\circ}C$) and medium(200 and $220^{\circ}C$) for 10 minutes, and at high(220 and $240^{\circ}C$) for 3 minutes. Meanwhile, roasting times were 20-30 minutes longer under low temperature condition and 3-5 minutes shorter under high temperature condition. The optimum roasting temperature and time were determined as $220^{\circ}C$ and 3 minutes for producing seed season, and as $220^{\circ}C$ and 5 minutes for sesame oil, respectively, in roasting with small quantity of sesame seeds. On the other hand, in the large scale roasting condition, those showed $240^{\circ}C$ and 15 minutes in for producing seed season, and $280^{\circ}C$ and 10 minutes and $260^{\circ}C$ and 15 minute for producing seed season in white-colored sesame variety and black-colored sesame variety, respectively.

• Journal of Korean Medicine Rehabilitation
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• v.21 no.2
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• pp.265-278
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• 2011

Objectives : This trial were conducted to evaluate the efficacy and adverse events of Bofutsusho-san(BTS) and Boiogiot-tang(BOT) by oriental obesity pattern identification on obese subjects, as compared to placebo. Methods : 166 subjects(body mass index ${\geq}25kg/m^2$) were recruited and randomized to receive BT(n=55), FH(n=55) or placebo(n=56) for 8 weeks. Anthropometric factors, serum lipid, glucose, blood pressure(BP), pulse rate, resting metabolic rate and oriental obesity pattern identification questionnaire were measured at baseline and 8 weeks. Adverse events and safety outcome variables were also checked during trials. Results : The frequency of top-scored oriental obesity pattern was ordered by indigestion(食積) > stagnation of the liver qi(肝鬱) > yang deficiency(陽虛) > spleen deficiency(脾虛) > phlegm(痰飮) > blood stasis(瘀血) in subjects. BTS group significantly decreased body weight, body mass index(BMI), waist circumference(WC), body fat mass, total cholesterol and HDL-cholesterol in stagnation of the liver qi(肝鬱) and WC in indigestion(食積). BOT group showed significant decrease of body weight, BMI, WC, and body fat mass in indigestion(食積) not in deficiency(虛症). Adverse events were reported most frequently in yang deficiency(陽虛) by BT group and stagnation of the liver qi(肝鬱) by BOT group. Conclusions : Bofu-tsusho-san was effective in treating obesity with stagnation of the liver qi(肝鬱). Obesity pattern identification could be a useful diagnostic tool predicting treatment effects and adverse events.

• Archives of design research
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• v.17 no.4
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• pp.15-26
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• 2004

After 19th century of Chosun Dynasty Gilsnagmunja-do such as longevity, good fortune, health, well-being which was explosively prevalent and Hyojemunja-do which was panoramically decorated with eight characters of filial piety, fraternal devotion, loyalty, trust, courtesy, commitment, integrity and humility for enlightment of the public under the name of political ideology are consistency or same origin in traditional concept of Orient. Therefore, in view of Western standard, they are showing an illustration and a photograph of characters in design. There are some differences in way of expressions. They were considerably popular not only in Chosun Dynasty but in China, Japan and Vietnam where belong to the cultural territory of chinese characters. Though, Hyojemunja-do which was built-up in the late period of Chosun Dynasty and developed fro chinese mode is a very peculiar iconography and mode of Chosun Dynasty. Hyojemunja-do is also classified from Chinese Nianhua designed for supply of Conficianism ethics or Folk Painting designed for practical use in chinese cultural territory. In the late period of 19th century, Hyojemunja-do which was re-built with creative modeling has been developed in peculiar mode in the province of Kyunggi, Kangwon(Kwan dong region), Kwanseo region, Jeju island and Namdo region by the diversified level of painters.

• Journal of Food Hygiene and Safety
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• v.29 no.2
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• pp.92-98
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• 2014

The safety of fake anti-impotence drugs (fake Viagra : 26 samples, fake Cialis : 25 samples) distributed in Gyeonggi province was studied by monitoring the concentrations of anti-impotence pharmaceutical ingredient and their analogues. The concentrations of anti-impotence pharmaceutical ingredient 4 specis and their analogues 17 specis were estimated using by HPLC/PDA, LC-MS/MS. The range of concentration of sildenafil in fake viagra was 40~199 mg/tablet, among them the portion of the concentrations of sildenafil over 150 mg/tablet exceeded 65%. 3 cases in tested samples contained sildenafil and tadalafil. The range of concentration of sildenafil in fake cialis was 102~249 mg/tablet, among them the portion of the concentrations of sildenafil over 150 mg/tablet exceeded 88%. One case in tested samples contained demethylhongdenafil (90 mg/tablet). These results indicate that there were many fake anti-impotence drug contained high level of anti-impotence pharmaceutical ingredients, a sustainable monitoring and the blocked distribution of fake anti-impotence drugs recommended.

• Korean Journal of Breeding Science
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• v.41 no.4
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• pp.635-639
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• 2009

A new peanut variety "Pungan"(Arachis hypogaea ssp. hypogaea L.) was developed at the Department of Functional Crop, NICS(National Institute of Crop Science), in Milyang in 2008. It was developed from the cross between the high-yielding cultivar "Saedl" and the very short stem cultivar "Satonoka". "Pungan", a Virginia palnt type, has 20 branches with long ellipseshaped large grains. The 100 grain weight was 88 g, 7 g heavier than the check variety Daekwang. This variety is more resistant to late leaf spot and web blotch compared to Daekwang, a check variety. Moreover, it is lodging resistant owing to its short stem. "Pungsan" outyielded the check variety by 16% with 4.67 MT/ha in regional yield trials.

• Korean Journal of Plant Resources
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• v.32 no.5
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• pp.589-614
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• 2019

To investigate the distribution of vascular plants growing at Mt. Guryong, we surveyed from March in 2016 to October in 2017. The flora of Mt. Guryong was classified as a total of 526 taxa comprising of 87 families, 298 genus, 449 species, 4 subspecies, 63 varieties, 10 forma. Among them, the endemic plants in Korea were investigated as 10 taxa of including Pseudostellaria coreana (Nakai) Ohwi. The Korean rare plants species were investigated as 16 taxa, among them degree of CR investigated as 1 taxa of Cypripedium macranthum Sw., VU investigated as 5 taxa of including Rhododendron micranthum Turcz., degree of LC investigated 9 taxa of including Clematis koreana Kom., degree of DD investigated 1 taxa of Adenophora grandiflora Nakai. Endemic plants were investigated as 14 taxa of including seudostellaria coreana (Nakai) Ohwi and The floristic special plants were a total of 84 taxa such as 2 taxa in degree V(in cluding Polypodium virginianum L.), 7 taxa in degree IV (including Anemone reflexa Steph. & Willd.), 21 taxa in degree III(including Celtis aurantiaca Nakai), 22 taxa in degree II (including Thelypteris phegopteris (L.) Sloss.) and 31 taxa in degree I (including Cimicifuga simplex (DC.) Turcz.) was carried out to provide basic data. The naturalized plants were investigated as 37 taxa of including Chenopodium ficifolium Smith., Thlaspi arvense L., Rumex crispus L. and the percentage of urbanization index was 11.53%, the naturalized ratio was 6.99% respectively.