• Title/Summary/Keyword: 의존성

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항마약성 약물의 효능검색 (인삼을 중심으로)

  • 김학성
    • Proceedings of the Korean Society of Applied Pharmacology
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    • 1994.04a
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    • pp.281-281
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    • 1994
  • 1) 인삼 엑기스는 morphine의 진통력을 길항하지 않으나 사포닌은 진통력을 길항한다. 2) 인삼 엑기스는 morphine의 내성 및 의존성 형성을 억제한다. 3) 인삼 엑기스는 몰핀의 역내성 (정신독성) 형성을 억제한다. 4. 결론 : Morphine의 진통력 길항작용, 내성 및 의존성 형성 억제 작용, 정신독성 형성억제작용 (자발운동에 대한 역내성 형성 억제 작용)등은 항마약성 약물의 효능검색에 좋은 지표가 될 것으로 사료된다.

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Time-Dependence of the Rheological Properties of Concentrated PVA Solution in DMSO (고농도 폴리비닐 알코올/디메틸 설폭사이드 용액의 유변학적 특성의 시간의존성)

  • 김남희
    • The Korean Journal of Rheology
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    • v.9 no.3
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    • pp.118-123
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    • 1997
  • 검화도와 분자량이 상이한 폴리비닐 알코올을 디멜틸 설폭사이드에 녹여 폴리비닐 알코올/디멜틸 설폭사이드 용액을 준비하고 동적 유변학적 특성에 대한 시간과 온도 의존성 을 고찰하였다. 고농도 폴리비닐 알코올 용액의 유변학적 특성은 시간 의존성을 보여주었다. 복합점도와 저장탄성률은 시간에 따라 증가하였다. 또한 저장 탄성률과 손실탄성률의 그래 프에서 저장탄성률은 신간에 따라 증가하였으나 기울기는 시간에 따라 증가하였다. 또한 저 장탄성률과 손실탄성률의 그래프에서 저장탄성률은 시간에따라 증가하였으나 기울기는 시간 에 따라 감소하였다. 유변학적 특성의 시간 의존성은 분자량이 높을수록, 측정온도가 높을수 록 더 두드러지게 나타났다.

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주가시계열의 무한분산과 장기의존성

  • Lee, Il-Gyun
    • The Korean Journal of Financial Studies
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    • v.12 no.1
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    • pp.1-17
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    • 2006
  • 쇄신의 분산이 무한인 주가시계열이 장기의존성 과정에 의하여 생성되고 있는가 또는 생성되고 있지 않는가를 검정하고자 한다. 기존의 연구가 쇄신의 분산이 유한한 경우에 한정하여 장기의존성 주가 과정에 대한 장기기억성이 검토되어왔다. 이 논문에서는 쇄신의 분산이 유한한 경우와 무한한 경우에 다같이 적용되는 방법들을 한국종합주가지수의 일별수익률에 적용하여 장기기억 모수를 추정 검정한다. 추정방법으로서는 분수 가우스 잡음, 가우스 분수적분 자기회기 이동평균, 선형 분수안정잡음 등이 형성되는 상황에 절대값 방법, 분수 방법과 총량화 Whittle 방법을 사용한다. 한국종합주가지수의 일별대수수익률 시계열은 분산이 무한한 경우에도 장기의존성과정에 의하여 생성되고 있다. 극치가 존재해도 장기기억과정이 형성 되고 있다.

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Natural Epistemic Attitude of Scientific Observation (과학적 관찰에 대한 자연스러운 인식적 태도)

  • Rhee Young-Eui
    • Journal of Science and Technology Studies
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    • v.1 no.1 s.1
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    • pp.155-178
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    • 2001
  • As is well known, logical positivists held the theory-independent of observation thesis(TIOT). On the other hand, the theories following the logical positivism typically represented by Hanson and Kuhn denied that there was a clear borderline between observation and theory, and held the theory-ladenness of observation thesis(TLOT). In order to mediate those theses I shall suggest a natural epistemic attitude (NEA) to the relation between theory and observation on the basis of the experimentalism. First, I discuss theories of Hanson and Kuhn as examples of views which profess TLOT. Then, I make a brief introduction of experimentalism and some critical discussions about TLOT follow from a point of the experimentalism: TLOT faces considerable counter-examples such as cases, 'observation precedes theory' and 'the combination of wrong theory and right observation'. I introduce a distinction between the guiding theory and the target theory in experimental situations and illustrate that TLOT loses its alleged power if we consider the distinction. Lastly, I suggest NEA, as conclusion of the paper, which can mediate among TIOT, TLOT, and experimentalism and takes a minimal ontology.

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Effects of Extracellular $Ca^{2+}$ and $Ca^{2+}$-Antagonists on Endothelium-Dependent Relaxation in Rabbit Aorta (토끼 대동맥 평활근의 내피세포 의존성 이완에 미치는 $Ca^{2+}$$Ca^{2+}$ 길항제의 효과)

  • Suh, Suk-Hyo;Goo, Yong-Sook;Park, Choon-Ok;Hwang, Sang-Ik;Kim, Ki-Whan
    • The Korean Journal of Physiology
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    • v.24 no.1
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    • pp.91-102
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    • 1990
  • The effects of extracellular $Ca^{2+}$ and various $Ca^{2+}$ antagonists on endothelium-dependent relaxation to acetylcholine were studied in the isolated rabbit thoracic aorta in order to elucidate the control mechanism of endothelium derived relaxing factor (EDRF) release. Endothelium was removed from aortic strips by gentle rubbing with cotton ball. The effect of hemoglobin on basal tension was also observed with hemolysate. The results obtained were as follows: 1) Endothelium-dependent relaxation (EDR) to acetylcholine (ACh) showed biphasic pattern; the initial rapid relaxation phase and the late slow relaxation phase. 2) With the depletion of the extracellular $Ca^{2+}$, EDR was gradually suppressed, especially the late slow relaxation. 3) Verapamil, nifedipine, $Mn^{2+}$ and $Cd^{2+}$ had not any effect on EDR, while $La^{3+}$ and $Co^{2+}$ suppressed EDR completely. 4) The resting tension of the strips with rubbed endothelium was not altered by the addition of hemoglobin. That of the strips with intact endothelium, however, was enhanced and EDR to ACh was completely blocked From these results, we suggest that extracellular $Ca^{2+}$ is necessary for ACh-induced slow relaxation while $Ca^{2+}$ antagonists have not any effect on EDR.

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The Effects of Output Sector Uncertainty on Dependence, Commitment and Strategic Performance: A Comparative Analysis on Korean and American Manufacturers (환경 불확실성이 한.미 제조업체의 의존성, 결속과 전략적 성과에 미치는 효과: 수요부문 환경불확실성을 중심으로)

  • Kim, Jong-Young;Bang, Ho-Yeol
    • International Commerce and Information Review
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    • v.16 no.1
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    • pp.163-183
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    • 2014
  • This paper empirically investigated whether the strategic performance of dependence and commitment on output sector uncertainty based on the data from manufacturing firms in Korea. U.S. Also, the proposed model was proven by the structural equation model with the data gathered from 105 manufacturing firms in Korea, 103 in U.S. The success of the members of channel having limited resources and capabilities depends on how they cope with environment. Especially, it is insispensable for manufacturing firms and distributing firms to build up win win systems when environmental uncertainty is high in the output sector. The findings were as follows. Hypothesis 1 was accepted in all the nations. Hypothesis 2 was accepted in the United States yet not in Korea. Hypothesis 3, 4 was accepted in Korea yet not in the United States. Hypothesis 5 was accepted in every nation as well. In the future, the dependence, commitment and strategic performance of manufacturing and distribution firms should be investigated from a mutual perspective, and additional data should be obtained by selecting more subjects. As for environmental uncertainty, the uncertainty of distribution environments as well as output sector uncertainty should equally be investigated by making a comparative analysis.

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Dependence of Elderly Peritoneal Dialysis Patients and Burden on Family Caregivers (노인 복막투석 환자의 의존성과 가족의 부담감)

  • Kim, Hyewon
    • Journal of Digital Convergence
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    • v.10 no.9
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    • pp.429-434
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    • 2012
  • This study was performed to examine the relationship between dependence of elderly peritoneal dialysis patients and burden on family caregivers. The subjects for this study were 50 elderly patients on Continuous ambulatory peritoneal dialysis(CAPD) who were registered in a hospital in Seoul and 50 their family caregivers. The data were collected from April 4 to August 15, 2011. The collected data were analyzed by the SPSS WIN 12.0 program. The mean score of dependence was 139.6 which means their experience of high level dependence. The mean score of burden was 84.2 which means their family caregivers experience of high level burden. Positive correlation was found between dependence of elderly peritoneal dialysis patients and burden on their family caregivers (r=.61, p=.000). It is considered that the study emphasizes for the healthcare providers to recognize dependence as the important nursing issue for elderly CAPD patients. And it is necessary to develop an nursing intervention for decreasing dependence of elderly CAPD patients and burden on their family caregivers.

Analysis of China's trade dependency on the countries participating in the Belt and Road initiative (일대일로 참여국가에 대한 중국의 무역 의존성 분석과 시사점)

  • Song, Min-Geun
    • Journal of Digital Convergence
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    • v.15 no.9
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    • pp.189-200
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    • 2017
  • The purpose of this study is to identify the characteristics of China's trade relationships with and dependency on the countries participating in the Belt and Road initiative and to present some implications. This study collected annual total imports, exports, and GDP data from the International Monetary Fund (IMF) on 198 countries and the National Bureau of Statistics of China (NBS) on 221 countries from 1995 to 2015. China's imports and exports have expanded considerably from the mid-1990s to the present, and China's dependence on imports and exports with the US and Japan has declined, while its dependence on the Middle East, South Africa, South America, and Southeast Asia has increased. China has a very high level of dependence on imports from and exports to the countries participating in the Belt and Road initiative, and as the Belt and Road project progresses, the mutual trade dependency between China and the other participating countries is expected to strengthen and expand.

An Experimental study to estimate physical properties of porous media by a permittivity method (유전율법에 따른 다공질 매질의 특성 파악을 위한 실험적 연구)

  • 김만일;니시가끼마코토
    • The Journal of Engineering Geology
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    • v.13 no.4
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    • pp.405-418
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    • 2003
  • Measurements of volumetric water content and saturation of porous media are very important factors in understanding the physical characteristics of soil, groundwater recharge by rainfall, pollutant movement, and slope failure. To measure such physical parameters, a permittivity method using electromagnetic wave is applied and use is made of the special permittivity response of understand to water and ethanol. In particular, the estimation is required because permittivity is influenced by the nature of the underground environment. In this study, we carried out experiments on the relative dependency of soil density, temperature and salinity of standard sand and granitic weathered soil using FDR-V system (Frequency domain reflectometry with vector network analyzer) within a frequency range of 1 - 18 GHz. The results of the study showed that the dielectric constants of standard sand and granitic weathered soil increased with increased volumetric water content of soil. However, the dependency of soil density was found to be a little low. Changes of dielectric constant with temperature appeared definitely in the real part of 1 GHz. That is, the dielectric constant of real part at 1 GHz of water and standard sand increased with the rise of temperature. However, ethanol showed decreased tendency. The study also showed that dielectric constant increased with increase in salinity at imaginary part of 1 GHz. It could be concluded from this study FDR-V system can adequately measure the physical properties of soil and the degree of salinity concentration of porous media within 1 GHz frequency range using dielectric constant.

Correction Method for Korean Dependency Parsing using Projectivity and Re-searching (투사성과 재탐색을 이용한 결정적 한국어 의존구조 분석의 보정기법)

  • Park, Young-Min;Seo, Jung-Yun
    • Korean Journal of Cognitive Science
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    • v.22 no.4
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    • pp.429-447
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    • 2011
  • In this paper, we propose a modified deterministic Korean dependency parser using a projectivity. The modified parser is improved by finding errors, such as cross dependency, from the original parsing results and correcting them according to the projectivity and head-final principles. Our parser also uses parsing history information in addition to rich features, which only a deterministic algorithm can use. Results on the modified parser for ETRI(2005) corpus, that consists of complex sentences, show that our parser outperforms other parsers.

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