• Title/Summary/Keyword: 의약품 안전 관리

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Discussion on the Introduction of Geriatric Specialized Pharmacists in Regional Pharmacy (지역 약국의 노인 전문 약사 도입 논의)

  • Jeong, Su-Cheol
    • The Journal of the Korea Contents Association
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    • v.19 no.8
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    • pp.303-315
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    • 2019
  • In 2018, 14.3 percent of South Korea's elderly population aged 65 or older entered an aged society and is expected to enter a super-aged society with more than 20 percent of the elderly population around 2025. Older adults often visit different medical institutions to take medicine, which requires medication management, such as interaction between each drug. In this study, we wanted to analyze the U.S. system, which specializes in drug management for the elderly, and Korea's system, which is about to enter a super-aged society, to find a systematic way to manage drugs for the elderly. The method of study was a systematic literature study on elderly drug management in Korea and the United States. Studies have shown that the United States has enacted the Medication Therapy Management (MTM) for the elderly and has been running the Senior Drug Enforcement Program. In Korea, a community care business is underway to manage drugs for senior citizens, but it is analyzed that the elderly need to have a special medicine system for senior citizens to use them more safely.

The Monitoring of some heavy metals in oriental herbal medicines and their intake rates (한약재 중 중금속의 모니터링 및 가용 섭취율 분석 연구)

  • Yim, Okkyoung;Han, Eunjung;Chung, Jaeyeon;Park, Kyungsu;Kang, Inho;Kang, Sinjung;Kim, Yunje
    • Analytical Science and Technology
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    • v.22 no.2
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    • pp.128-135
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    • 2009
  • This paper is the monitoring results of some heavy metals (lead, cadmium, arsenic, mercury) in herbal medicines and their intake rates. The monitoring of lead, cadmium, arsenic and mercury was carried out on 600 samples with 60 kinds of herbal medicines. And the transfer ratio of heavy metals in the water-boiled drinks w as calculated. The results show that lead was detected over the Maximum Residue Limits (MRL) in 10 samples (7 species). Cadmium was detected over the MRM in 69 samples (19 species). Arsenic was detected over the MRM in 3 samples (3 species). Mercury was detected over the MRM in 13 samples (10 species). We need continuously monitoring to ensure confidence and safety for these herbal medicines. In case of the water-boiled drink, average intake rates of lead, cadmium, arsenic and mercury are 9.77%, 6.72%, 26.1% and 6.79%, respectively.

Monitoring of aquatic medicine managements in South Korea (국내 수산용의약품의 관리 현황 모니터링)

  • Kim, Young-Jae;Seo, Jung-Soo;Park, Jeon-Oh;Jeong, Ah Reum;Lee, Ji-Hoon
    • Journal of fish pathology
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    • v.32 no.1
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    • pp.37-43
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    • 2019
  • Due to the rapid global expansion of aquaculture industry during the past decades, production volume of aquatic organisms has accordingly grown. This has been accompanied by a rise in the incidence of diseases in aquatic organisms, leading to an increased use of aquatic medicines. While aquatic medicines are essential for the prevention and treatment of diseases of aquatic organisms, misuse can cause evolution of antibiotic-resistant bacteria and pose serious problems to the safety and hygiene of fisheries products. In this study, we surveyed and compared, by analyzing data compiled by all national control centers for aquatic animal diseases in South Korea, to estimate the amount of aquatic medicines sold in different regions between 2012 through 2015. Since we also examined the marketing routes of aquatic medicines, this basic data can be utilized for policy implementation to improve drug safety. In the future research, however, it will be clearly necessary to estimate directly the amounts of drugs actually applied to aquaculture organisms. The current sales figure data should be helpful for preparation of an effective system for aquatic drug use management.

Testing and Analysis of Tube Voltage and Tube Current in The Radiation Generator for Mammography (유방촬영용 방사선발생장치의 관전압과 관전류 시험 분석)

  • Jung, Hong-Ryang;Hong, Dong-Hee;Han, Beom-Hui
    • Journal of radiological science and technology
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    • v.37 no.1
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    • pp.1-6
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    • 2014
  • Breast shooting performance management and quality control of the generator is applied to the amount of current IEC(International Electrotechnical Commission) 60601-2-45 tube voltage and tube current are based on standards that were proposed in the analysis of the test results were as follows. Tube voltage according to the value of the standard deviation by year of manufacture from 2001 to 2010 as a 42-3.15 showed the most significant, according to the year of manufacture by tube amperage value of the standard deviation to 6.38 in the pre-2000 showed the most significant, manufactured after 2011 the standard deviation of the devices, the PAE(Percent Average Error) was relatively low. This latest generation device was manufactured in the breast of the tube voltage and tube diagnosed shooting the correct amount of current to maintain the performance that can be seen. The results of this study as the basis for radiography diagnosed breast caused by using the device's performance and maintain quality control, so the current Food and Drug Administration "about the safety of diagnostic radiation generator rule" specified in the test cycle during three years of self-inspection radiation on a radiation generating device ensure safety and performance of the device using a coherent X-ray(constancy) by two ultimately able to keep the radiation dose to the public to reduce the expected effect is expected.

Application of delphi method to the technology level assessment of food safety (델파이기법을 활용한 식품안전 기술수준 진단)

  • Gwon, So Young;Lee, Ye Seul
    • Food Science and Industry
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    • v.51 no.3
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    • pp.209-217
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    • 2018
  • Delphi technique is widely used to develop consensus on group opinion. It is important to identify the strategic technologies and evaluate technology level for the establishment of national R&D policy to upgrade technology level. The aim of this article was to reflect on Food Safety technology level by using Delphi methodology. And, competitiveness of patents and journal articles is evaluated for Korea, USA, Japan, China and EU. As a result, USA is the most competitive country for all technology categories. The average technology level of Korea was 79.5% of world-top coungry and average technological gap was 6.1 years. Korea is grouped in middle-lower class for overall food safety technology level. However, there are some variances among the level of technologies. As a result of this study, food safety research management needs to expand R&D investment and training of food safety specialist. The results of this research can be utilized to establish a road map for transportation R&D and plans.

An Analysis of Changes in Social Issues Related to Patient Safety Using Topic Modeling and Word Co-occurrence Analysis (토픽 모델링과 동시출현 단어 분석을 활용한 환자안전 관련 사회적 이슈의 변화)

  • Kim, Nari;Lee, Nam-Ju
    • The Journal of the Korea Contents Association
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    • v.21 no.1
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    • pp.92-104
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    • 2021
  • This study aims to analyze online news articles to identify social issues related to patient safety and compare the changes in these issues before and after the implementation of the Patient Safety Act. This study performed text mining through the R program, wherein 7,600 online news articles were collected from January 1, 2010, to March 5, 2020, and examined using keyword analysis, topic modeling, and word co-occurrence network analysis. A total of 2,609 keywords were categorized into 8 topics: "medical practice", "medical personnel", "infection and facilities", "comprehensive nursing service", "medicine and medical supplies", "system development and establishment for improvement", "Patient Safety Act" and "healthcare accreditation". The study revealed that keywords such as "patient safety awareness", "infection control" and "healthcare accreditation" appeared before the implementation of the Patient Safety Act. Meanwhile, keywords such as "patient safety culture". and "administration and injection" appeared after the act's implementation with improved ranking of importance pertaining to nursing-related terminology. Interest in patient safety has increased in the medical community as well as among the public. In particular, nursing plays an important role in improving patient safety. Therefore, the recognition of patient safety as a core competency of nursing and the persistent education of the public are vital and inevitable.

Studies on the Usage of Compound Flavorings in Korea (국내의 조합향료 사용실태 조사)

  • Kim, Hee-Yun;Yoon, Hae-Jung;Hong, Ki-Hyoung;Park, Sung-Kwan;Choi, Jang-Duck;Choi, Woo-Jeong;Kim, Ji-Hye;Park, Hui-Og;Jin, Myeong-Sig;Lee, Chul-Won
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.33 no.8
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    • pp.1407-1413
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    • 2004
  • This study was performed to investigate the usage and management of flavorings inside or outside (Europe, Japan, JECFA and USA) for that establish a legislation about the flavoring management in Korea. Also, this study contributed to prevent confusion when manufacturers produce flavorings used in food industry. 6,434 among 8,386 flavorings authorized by Korea Food and Drug administration are compound flavorings, and 618 among 6,434 compound flavorings are synthetic flavorings. Many other substances except for flavorings are using as solvent in flavoring manufacture. Flavorings used in food industries of Korea are listed at least one among FEMA, JECFA, CoE and JFFMA except for isooctyl acetate and tricyclene. 493 items out of total 618 synthetic flavorings have completed safety evaluation by JECFA. 106 synthetic flavorings out of the rest listed FEMA as GRAS and 20 synthetic flavorings used in Japan. The replier answered that the most frequently used flavorings are strawberry, grape, orange, plum, lemon and vanilla flavor and that the usage of flavoring added to foodstuffs is less than 0.5%.

The Design of Messaging System for Prescription Data Interchange (처방전달을 위한 메시징시스템의 설계)

  • 김동호;류근호;손현준
    • Proceedings of the Korea Society for Industrial Systems Conference
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    • 1999.12a
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    • pp.209-218
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    • 1999
  • 처방전달시스템은 처방의 수행은 의사가, 그에 따른 의약품조제는 약사가 수행함으로써 의약품의 오․남용을 방지하기 위한 의약분업의 실시에 따른 국민불편의 최소화와 약화사고에 따른 인증문제 등을 지원하기 위한 정보시스템이다. 처방전달시스템은 환자 개인정보의 허용된 범위 내에서의 공유와 공유를 위한 각종 개인정보 보호장치, 처방의 안전한 전달을 위한 내용의 비밀보장과 위변조방지 및 송신자와 수신자의 인증을 위한 장치가 필수적으로 필요하다. 또한 자료의 생명주기 측면에서 본다면, 처방전의 생성은 병․의원에서 이루어지며 소멸은 약국 및 환자에의해 이루어진다. 자료의 유통과정에 살펴보면 처방전달시스템의 주요성공요인은 정보의 생산자인 병․의원(의사)의 적극적인 정보제공의지와 이를 지원하는 편리한 정보시스템의 구축이라고 할 수 있다. 정보의 생산자인 병․의원 정보시스템 환경은 다양하고 복잡하기 때문에 기존의 애플리케이션을 이용하면서 처방의 전송을 위해서는 기존 애플리케이션 및 플랫폼에 독립적이며 자료의 적합한 취합과 통합이 가능하도록 지원하는 시스템이 필요하다. 처방전달 메시징시스템은 이러한 복합적인 정보시스템 환경을 지원하며 동시에 처방정보의 안전한 전달을 위해 플랫폼으로 실행될 수 있는 시스템을 말한다. 또한 처방의 비교적 짧은 생명주기와 지역적 생산, 유통구조를 적합하게 지원하기 위해 지역별 독립시스템의 구축과 공통정보 활용을 위한 중앙시스템과의 역할분담 모델에 근거한 분산시스템의 구축이 요구된다. 본 연구에서의 처방전달 메시징시스템은 일반적인 메시지서비스의 특성을 기본으로 자료전달을 위해 자료 암호화와 복호화, 송신자와 수신자에 대한 인증 및 자료접근 제한기능을 제공하며 각 클라이언트와 서버간의 실시간 연결 혹은 지연연결을 지원하는 독립적인 애플리케이션이다. 이러한 처방전달 메시징시스템을 구성하는 각 요소에 대해 정의하고 개념적 모델을 설계하고자 한다.에게 청구되며, 소비자에게 전송 되는 청구서는 사용자DB를 참조하여 사용자가 미리 정의한 원하는 형태로 변환되어 전달되며, 필요시 암호화 과정을 거치는 것이 가능해야 한다. 전송된 청구서는 전자우편의 경우, 암호해독이 가능한 전용 브라우저를 통해 열람 되며, 이는 다시 전용 브라우저를 통해 지불인증이 승인되어 청구 제시서버에게 전송된다. EBPP 시스템의 제어 흐름은 크게 기업이 청구 정보를 소비자에게 제시하는 흐름과 소비자의 지불 승인으로 인해 기업이 은행에 지불을 요구하는 흐름으로 구분할 수 있다. 본 논문에서는 통합 청구서버 및 정구 제시서버의 역할 및 구성 요소들에 대해 서술하고, EBPP 시스템과 연동하여야 하는 메일 서버와의 상호 작용에 대해 서술할 것이다. 본 시스템을 아직 구현이 되지 않은 관계로 시스템의 성능 등의 수치적 결과를 제시할 수 없는 상태다., 취약계층을 위한 일차의료, 의약관리), ${\circled}2$ 보건소 조직 개편 및 민간의료기관과 협력체계 확립, ${\circled}3$ 전문인력 확보 및 인력구성 조정, 그리고 ${\circled}4$ 방문보건사업의 강화 등이다., 대사(代謝)와 관계(關係)있음을 시사(示唆)해 주고 있다.ble nutrient (TDN) was highest in booting stage (59.7%); however no significant difference was found among other stages. The concentrations of Ca and P were not different among mature stages. According to these results, the yellow ripe period is appropriate to harvest the whole crop rice for forage considering dry matter yields,

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Effects of Tiamulin on Starry Flounder, Platichthys stellatus Infected with Streptococcus parauberis HFTC0083 (Tiamulin이 Streptococcus parauberis HFTC0083에 감염된 강도다리(Platichthys stellatus)에 미치는 영향)

  • Joo, Min-Soo;Kim, Boseong;Kim, Do-Hyung;Seo, Jung-Soo;Kwon, Mun-Gyeong;Jee, Bo-Young;Park, Chan-Il
    • Journal of Marine Life Science
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    • v.4 no.1
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    • pp.29-37
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    • 2019
  • In order to control disease caused by multi-drug resistant bacteria in the aquaculture, the use of veterinary antibiotics, which are prohibited to fish, is increasing, instead of the existing fisheries antibiotics. Among them, tiamulin is illegally used in some cultured fish because it exhibits effective antibacterial activity against Gram-positive bacteria. To prevent unauthorized use, treatment of fish should be accompanied by a prescription from veterinarians or fisheries disease managers through research on fish of tiamulin. Tiamulin was injected intramuscularly at 5, 10 and 15 mg kg-1 for the streptococcus-infected starry flounder, but did not show any therapeutic effect. Oral administration at a concentration of 15 and 30 mg kg-1 was similarly ineffective. The concentrations of 30 and 60 mg kg-1 resulted in death due to toxicity of antibiotics. Therefore, it is inappropriate to treat antibiotics with streptococcus-infected starry flounder.

Current State and Applications of the Electronic Clinical Trial Process in Korea (국내 임상시험 전자화 현황과 적용방안)

  • Wang, Boram;Choi, Inyoung
    • The Journal of the Korea Contents Association
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    • v.13 no.4
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    • pp.281-289
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    • 2013
  • As the number of clinical trials conducted in Korea increases, the need of the Electronic Data Capture (EDC) system for effective clinical data management is also increased. Recently, the Korea Food and Drug Association published 'Guideline for the Electronic Clinical Trial Data Management and Processing' and it would be the foundation for establishing regulation of electronic clinical data management. In this research, we conducted the survey regarding adoption rate of EDC system in clinical trials in hospitals, Contract Research Organizations (CRO), and pharmaceutical companies. And the perceived importance and the ease of application for the Guideline were investigated. The adoption rates of EDC system was 77.6% but it mostly applied to less than five trials. Also EDC system was mostly used in phase I and phase II trials and the utilization rate of CRO was the highest. The perceived importance for the Guideline was high among all three organizations but, in case of the perceived ease of its application, CRO was the highest. Also, the perceived importance of the clinical data standard was high and the standard for data collection was mostly required. However, the comprehension for the global standard of the electronic data was relatively low, so that education is required. This result would be the foundation to increase the electronic clinical trials and develop proper regulation and principles for clinical data standards in Korea.