• Title/Summary/Keyword: 은 나노 입자

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Preparation and Characterization of Casein Nanoparticles with Various Metal Ions as Drug Delivery Systems (다양한 금속 이온을 이용한 카세인 단백질 나노입자 형성 및 약물 전달체 특성 연구)

  • Minju Kim;Seulgi Lee;Joon Sig Choi
    • Applied Chemistry for Engineering
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    • v.34 no.2
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    • pp.121-125
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    • 2023
  • Casein is a milk protein and one of the most important nutrients in milk. The composition is over 80% in cow's milk and about 20~45% in human's milk. Casein is highly biocompatible and biodegradable, so it has been studied for various biomedical materials applications as well as drug delivery systems. It is widely known that casein can be prepared as nanoparticles in the presence of the Ca2+ metal ion. Because casein is amphiphilic, hydrophobic drugs could be loaded inside to form a protein-based drug delivery system. In this study, we studied the optimum conditions for casein nanoparticle formation using natural metal ions present in the body, such as calcium, magnesium, zinc, and iron. It was confirmed that nanoparticles have a uniform size of around 150 nm and negative zeta potential values. In addition, it was demonstrated that casein nanoparticles have a cell viability of more than 80% and efficient intracellular uptake properties using confocal microscopy. From the results, it was also shown that the casein nanoparticles prepared using various metal ions have the potential to be biocompatible drug delivery carriers.

Biogenic Synthesis of Metallic Nanoparticles and Their Antibacterial Applications (금속 나노입자의 생체 합성과 항균적 적용)

  • Patil, Maheshkumar Prakash;Kim, Jong-Oh;Seo, Yong Bae;Kang, Min-jae;Kim, Gun-Do
    • Journal of Life Science
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    • v.31 no.9
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    • pp.862-872
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    • 2021
  • Recent studies on synthesis of metallic nanomaterials such as silver (Ag), gold (Au), platinum (Pt), cerium (Ce), zinc (Zn), and copper (Cu) nanoparticles (NPs) using plants and microbes are attracted researchers for their wide range of applications in the field of biomedical sciences. The plant contains abundant of bioactive contents such as flavonoids, alkaloids, saponins, steroids tannins and nutritionals components. Similarly, microbes produce bioactive metabolites, proteins and secretes valuable chemicals such as color pigments, antibiotics, and acids. Recently reported, biogenic synthesis of NPs in non-hazardous way and are promising candidates for biomedical applications such as antibacterial, antifungal, anti-cell proliferative and anti-plasmodia activity. All those activities are dose dependent, along with their shape and size also matters on potential of NPs. Microbes and plants are great source of metabolites, those useful in biomedical field, such metabolites or chemicals involved in synthesis of NPs in an ecofriendly way. NPs synthesized using microbes or plant materials are reveals more non-toxic, facile, and cost-effective compare to chemically synthesized NPs. In present review we are focusing on NPs synthesis using biological agents such as microbes (bacteria, fungi and algae) and plant, characterization using different techniques and their antibacterial applications on pathogenic Gram-positive and Gram-negative organisms.

Change of Specific Resistance of Inkjet-Printed Silver Nanoparticles According to Sintering Methods (잉크젯으로 인쇄된 실버 나노입자의 소결방법에 따른 비저항 변화)

  • Moon, Yoon-Jae;Hwang, Jun-Young;Lee, Sang-Ho;Kang, Kyung-Tae;Kang, Heui-Seok;Cho, Young-June
    • Proceedings of the KIEE Conference
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    • 2011.07a
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    • pp.1716-1717
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    • 2011
  • 잉크젯으로 인쇄된 실버 나노입자가 오븐, 레이저, 전기를 이용한 소결방법에 의해 소결되었다. 전도성 라인은 드롭 온 디맨드형(drop-on-demand) 잉크젯 프린터에 의해 유리 기판 위에 인쇄되었다. 레이저를 이용한 소결은 레이저 강도와 조사시간을 변화시키면서 실버나노입자를 소결하였고, 전기 소결은 인쇄된 라인에 정전류 방식을 이용하여 인가해주는 전류값을 변화시키면서 소결하였다. 소결방법에 따른 비저항변화, 단면적 변화, 미세구조변화를 관찰하였고 이 결과를 오븐 소결 결과와 비교하였다. 전기를 이용하여 소결하였을 경우 가장 낮은 비저항을 얻을 수 있었고, 은의 고유 비저항에 비하여 1.7배 큰 비저항을 얻었다.

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Study of Anti-bacterial Properties for Impregnated Activated Carbon by Silver Nano-particles (은나노 입자가 첨착된 활성탄의 항균특성에 관한 연구)

  • Lee, Chul-Jae;Kim, Dong-Yeub;Kim, Byung-So
    • Applied Chemistry for Engineering
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    • v.18 no.4
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    • pp.396-399
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    • 2007
  • In present work, the anti-bacterial effect of silver/activated carbon (Ag/C) composites prepared by the ${\gamma}$-irradiation of $AgNO_3$ solution on Escherichia coli (E. coli) has been studied. Characteristics of the Ag/C composites were identified by scanning electron microscopy (SEM), X-ray diffraction (XRD) and atomic absorption spectroscopy (AAS). The inhibitory concentration of E. coli was found to be 0.387 ppm and the sterilizing concentration for the tested organism was 1.017 ppm. These results support the evidence that Ag/C composites have strong antibacterial activity to E. coli.

Electrical Doping of Graphene Films by Hybridization of Nickel Nanoparticles

  • Lee, Su-Il;Song, U-Seok;Kim, Yu-Seok;Cha, Myeong-Jun;Jeong, Dae-Seong;Jeong, Min-Uk;Jeon, Cheol-Ho;Park, Jong-Yun
    • Proceedings of the Korean Vacuum Society Conference
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    • 2012.08a
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    • pp.403-403
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    • 2012
  • 그래핀(graphene)은 우수한 전기적, 물리적인 특성을 지닌 물질로써 다양한 분야에서 이를 활용하려는 노력들이 활발히 진행되고 있다. 그중 그래핀을 채널로 이용하는 전계효과 트랜지스터(field effect transistor)로의 응용에 있어, 가장 핵심적인 도전과제는 전하농도(carrier concentration)의 제어 및 에너지 밴드갭(energy bandgap) 형성이라 할수 있다. 최근 다양한 물질을 이용한 도핑을 통해 이를 해결하기 위한 노력들이 진행되고 있는 추세이다. 본 연구에서는 열화학 기상 증착법(Thermal chemical vapor deposition)을 통해 합성된 단일층의 그래핀에 염화니켈 나노입자의 분산액을 스핀코팅 한후 열처리를 통해 그래핀-니켈 나노입자의 하이브리드 구조를 제작하였다. 제작된 그래핀-니켈 나노입자 하이브리드 물질의 구조적 특징을 주사 전자 현미경(Scanning electron microscope)과 원자힘 현미경(Atomic force microscopy)을 통하여 확인하였다. 또한 니켈 분산액의 농도와 도핑효과 와의 상관관계를 라만분광법(Raman spectroscopy)과 이온성 용액법(Ionic liquid)을 이용한 전계효과 특성분석을 통해 조사하였다. 나노입자의 형성 메커니즘은 X-선 광전자 분광법(X-ray photoelectron spectroscopy)을 통하여 규명하였다.

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Improved Electrical Conductivity of CFRP by Conductive Nano-Particles Coating for lightning Strike Protection (낙뢰손상방지를 위한 전도성 나노입자 코팅에 의한 탄소섬유 복합재료의 전기전도도 향상 연구)

  • Ha, Min-Seok;Kwon, Oh-Yang;Choi, Heung-Soap
    • Composites Research
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    • v.23 no.1
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    • pp.31-36
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    • 2010
  • The improvement of electrical conductivity of carbon-fiber reinforced plastics (CFRP) has been investigated by silver nano-particles coating for the purpose of lightning strike protection. Silver nano-particles in colloid were sprayed on the surface of carbon fibers, which were then impregnated by epoxy resin to form a CFRP specimen. Electrical resistance was measured by contact resistance meter which utilize the principles of the AC 4-terminal method. Electrical resistance value was then converted to electrical conductivity. The coated silver nano-particles on the carbon fibers were verified by SEM and EDS. The electrical conductivity was increased by three times of the ordinary CFRP.

나노입자를 이용한 의학진단

  • 조경아;김진형;박병준;이준우;김현석;김상식
    • Electrical & Electronic Materials
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    • v.17 no.4
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    • pp.32-39
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    • 2004
  • 차세대 신기술로 부상하고 있는 나노바이오 기술(Nano-Bio Technology)은 10억분의 1이라는 정밀도를 바탕으로 원자나 분자를 조작해 새로운 물질을 만들고 시스템을 창조하는 나노기술(Nanotechnology : NT)과 생명현상을 연구 대상으로 하는 바이오 기술 (Biotechnology : BT)이 융합된 분야이다. 근본적으로 무기물을 다루는 NT와 생명체를 다루는 BT가 융합할 수 있는 것은 BT의 궁극적인 연구대상인 DNA, RNA, 단백질의 크기가 수 나노미터로 NT의 연구대상의 크기와 동일하다는 데에 있다.(중략)

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