• Title/Summary/Keyword: 육아종

Search Result 205, Processing Time 0.034 seconds

Intra-abdominal Retained Surgical Gauze in Two Dogs (개의 복강내 잔존 수술용 거즈 2예)

  • Choi, Ho-Jung;Lee, Ki-Ja;O, I-Se;Lee, Jae-Yeon;Jee, Hyun-Chul;Park, Seong-Jun;Jeong, Seong-Mok;Lee, Young-Won
    • Journal of Veterinary Clinics
    • /
    • v.24 no.2
    • /
    • pp.238-243
    • /
    • 2007
  • This report describes the retained surgical gauze in two dogs that had ovariohysterectomy previously. The elapsed time between surgery and diagnosis of retained surgical gauze in two dogs was 30 and 16 months, respectively. Radiographic signs included localized abdominal mass (case 1, 2) and soft tissue swelling (case 2). Retained surgical gauze was imaged by survey radiography, ultrasonography and computed tomography (CT). Ultrasonography revealed a hypoechoic mass with irregular hyperechoic center in case 1, and hypoechoic mass with oval hyperechoic center and acoustic shadowing in case 2. In CT examination of case 2, hyperdense mass with a thick peripheral rim enhancing in contrast study was shown. Cytologic examination of both cases revealed abscess and granuloma respectively. The lesions were surgically removed. The possibility of retained surgical gauze should be considered in animals with a history of previous surgery with abnormal mass.

Expression of the Epidermal Growth Factor and Tumor Necrosis Factor-$\alpha$ in Lung Cancer (폐암에서 Epidermal growth factor와 Tumor Necrosis Factor-$\alpha$의 발현)

  • 장덕기;이충석;박성달;김송명
    • Journal of Chest Surgery
    • /
    • v.34 no.2
    • /
    • pp.138-147
    • /
    • 2001
  • 배경: 폐암발생에 EGF의 자가 분비는 암의 성장과정에 직, 간접적인 영향을 주고 있으며, TNF-$\alpha$는 면역 반응의 급성체로서 폐암의 발생을 억제하고 이미 발생한 폐암종의 치료에도 이용되고 있는 실정이다. 폐암 조직과 혈장에서 epidermal growth factor(EGF)와 tumor necrosis factor-$\alpha$(TNF-$\alpha$)를 면역 방사선 분석법을 이용하여 정량분석 하여 발현 정도를 분석해보고자 하였다. 대상 및 방법: 폐암환자 20례와 양성종양 및 육아종 환자 4례에 대해서 AJCCS에 의한 조직학적 분류와 TNM 분류에 따라 구분하여 절제수술을 받은 환자를 대상으로 수술전 혈액을 채취하고 수술직후 적출한 표본을 암이 없는 건강하다고 판단되는 대조조직과 폐암조직에서 일정량의 조직을 절취하여 액화질소 내에 실험시까지 급속 냉동보관 하였다. 수술후 혈액을 재 채취하여 혈장을 분리하여 냉동고에 검사시까지 보관하였다. EGF의 정량은 Human Epidermal Growth Factor kit(Amersham Phamacia Biotech, England)를 사용하였으며, TNF-$\alpha$ 정량은 TNF-$\alpha$ IRMA kit(Biosouce, Belgium)을 사용하여 IRMA 방법으로 각각 정량분석하여 표현유무를 연구한 결과 다음과 같은 결론을 얻었다. 결과: 1. 대조조직, 양성종양 및 육아종과 폐암 수술전후의 조직과 혈청 모두에서 EGF와 TNF-$\alpha$가 발현되었다. 2. EGF와 TNF-$\alpha$의 농도는 대조조직과 양성종양(0.11$\pm$0.06 ng/ml, 20,3$\pm$9.08 pg/ml)에 비하여 폐암조직(0.13$\pm$0.05 ng/ml, 34.34$\pm$47.74pg/ml)에서 유의하게 높은 농도가 발현되고 있었다. 3. 폐암중 선암조직에서 특히 TNF-$\alpha$(80.92$\pm$104.08 ng/ml)의 발현이 강하게 나타났다. 4. 혈청내의 EGF와 TNF-$\alpha$의 발현되는 양이 조직내의 양보다도 높았다. EGF는 5.7배정도 TNF는 1.3배정도 강하게 표현되었다. 5. 폐암의 조직학적 종류에 따라서 EGF는 거의 차이가 없었으나 TNF-$\alpha$ 정량치에는 차이가 있었다. 6. TNM stage가 진행함에 따라 EGF는 농도가 증가하였고 TNF-$\alpha$는 오히려 감소하는 반대되는 교차현상이 있었다. 7. 수술직후 EGF는 증가하였으나 TNF-$\alpha$는 오히려 감소하였다. 결론: 결론적으로 저자는 암조직과 대조조직간에 EGF와 TNF-$\alpha$의 표현량의 차이가 있음을 관찰하였으며 또한 조직과 혈청사이에도 표현량에 차이가 있으며 조직보다도 오히려 혈청내의 농도가 높다는 사실을 관찰하였다. EFG와 TNF-$\alpha$는 정상조직이나 양성조직과 폐암조직 모두에서 분비작용되는 cytokines으로 세포기능에 따라 다양하게 표현이 되며 계속적인 연구로서 밝혀야만 할 과제라고 판단된다.

  • PDF

Intravascular Papillary Endothelial Hyperplasia (Masson's hemangioma) Presenting as a Forearm Mass (전완부에 발생한 내혈관 유두내피 증식증(Masson 혈관종))

  • Chun, Young-Soo;Rhyu, Kee-Hyung;Kim, Sang-Hwan
    • The Journal of the Korean bone and joint tumor society
    • /
    • v.15 no.1
    • /
    • pp.59-64
    • /
    • 2009
  • Intravascular papillary endothelial hyperplasia (IPEH, Masson's hemangioma) is a non neoplastic reactive endothelial proliferation most commonly located in the skin or subcutaneous tissues although it has been reported in multiple locations throughout the body. This lesion may arise from malformed or normal vessels primarily, and may develop with hemangioma, pyogenic granuloma, or lymphangioma. This lesion, though benign, is clinically important since it may present as a mass and be confused histologically with angiosarcoma. The authors report a 27 years old patient with a mass in his forearm which results in intravascular papillary endothelial hyperplasia.

  • PDF

Clinical Application of Botulinum Toxin to Contact Granuloma and Vocal Nodule (보툴리눔 독소를 이용한 성대육아종과 성대결절 치료)

  • Lee, Seung Won
    • Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
    • /
    • v.30 no.2
    • /
    • pp.82-86
    • /
    • 2019
  • In the field of otolaryngology-head and neck surgery, botulinum toxins are widely used for the treatment of spasmodic dysphonia and vocal tremors. Recently, the applications of botulinum toxin have gradually expanded with time, to include vocal fold granuloma, mutational falsetto, bilateral vocal cord paralysis, and chemical reduction for arytenoid dislocation as an adjunctive modality. According to a nation-wide multicenter study conducted by the Korean Society of Laryngology, Phoniatrics and Logopedics for treatment modality of contact granuloma, among the various treatment modalities, botulinum toxin injection showed the highest response rate and lowest recurrence rate in both primary and refractory cases. Therefore, botulinum toxin could be reserved as a second-line treatment for contact granuloma in which the first treatment was not effective, but also could be used as a first-line treatment depending on the patient's and institution's situation. For recalcitrant nodules, injection of botulinum toxin into the bilateral thyroarytenoid muscle will reduce glottal contact force and result in a forceful chemical voice rest. In special situations, botulinum toxin injection could be one of the alternative treatment options for recalcitrant vocal nodules.

Two Cases of Pulmonary Eosinophilic Granuloma (폐 호산구성 육아종 2예)

  • Choi, Wan-Young;Yoo, Yong-Keol;Park, Dong-Il;Shin, Dong-Ho;Park, Sung-Soo;Lee, Jung-Hee;Jeon, Seok-Chul;Chung, Won-Sang;Park, Chan-Pil;Park, Moon-Hyang;Lee, Jung-Dal
    • Tuberculosis and Respiratory Diseases
    • /
    • v.39 no.2
    • /
    • pp.186-193
    • /
    • 1992
  • Eosinophilic granuloma (histiocytosis $\times$) is an uncommon granulomatous disorder affecting the mononuclear phagocytic cell system caused by unknown etiology. When confined to the lungs, it is also known as pulmonary eosinophilic granuloma or pulmonary histiocytosis $\times$. After the first case was described in 1951 by Farinacci et ai, more 250 cases were reported in the English literature. However only 4 cases has been introduced in our country. We describe two additional cases. In both cases, open lung biopsies are performed for definite diagnosis and examined by immunohistochemical stain for S-100 protein and electron microscopy for ultrastructural identification of Birbeck granule.

  • PDF

Unusual Presentation of Traumatic Neuroma of the Medial Plantar Nerve after Deep Laceration Mimicking a Foreign Body Granuloma: A Case Report (이물 육아종으로 오인된 심부 열상 이후 발생한 비정상적인 내측 족저 신경의 외상성 신경종: 증례 보고)

  • Woo, Seung Hun;Kim, Tae Woo;Bae, Jung Yun
    • Journal of Korean Foot and Ankle Society
    • /
    • v.21 no.4
    • /
    • pp.174-178
    • /
    • 2017
  • Traumatic neuromas are rare benign tumors that are common after trauma or surgery and are usually accompanied by obvious symptoms of pain. Most reports show neuromas in the face, neck, and limbs, and the traumatic neuroma of the medial plantar nerve has rarely been reported. We encountered a traumatic neuroma of the medial plantar nerve after a deep laceration mimicking a foreign body granuloma. A small mass lesion was found around plantar aponeurosis with heterogeneous high signal intensity in the T2 fat suppression view and slightly enhanced intensity in the magnetic resonance imaging that suggested a foreign body granuloma. The lesion was diagnosed pathologically as a traumatic neuroma. A satisfactory clinical result was obtained after excision of the traumatic neuroma and burial of the proximal and distal stumps to the adjacent muscle at the secondary operation.

Radiation Therapy (RT) of Midline Granuloma (중앙성육아종의 방사선치료)

  • Kwon, Hyoung-Cheol;Oh, Yoon-Kyeong;Gil, Hak-Jun;Yoon, Sei-Chul;Bahk, Yong-Whee
    • Radiation Oncology Journal
    • /
    • v.4 no.2
    • /
    • pp.135-139
    • /
    • 1986
  • Seven patients having midline granuloma received local irradiation from March 1983 to June 1986. Clinically, all of the 7 patients had pansinusitis with necrotic destruction of the involved sites and one case revealed colonic lesion. Each of the patients received a tumor dose of $4,000\~5,000 cGy/5\~6$ wks to the upper aerodigestive tract using a 6-MV linear accelerator. Complete and partial remission occured in 3 patients each, and in one case, the disease progressed despite of the irradiation.

  • PDF

CT Findings of Granulomatous Pneumocystis jiroveci Pneumonia in a Patient with Multiple Myeloma (다발성 골수종 환자에서 발생한 육아종성 폐포자충 폐렴의 컴퓨터단층촬영 소견)

  • So Ra Shin;Tae Sung Kim;Joungho Han
    • Journal of the Korean Society of Radiology
    • /
    • v.83 no.1
    • /
    • pp.218-223
    • /
    • 2022
  • Although the typical CT findings of Pneumocystis jiroveci pneumonia (PJP) include diffuse or multifocal areas of ground-glass opacities in both lungs, it can also rarely manifest as multiple pulmonary nodules. We report a rare case of atypical PJP in an immunocompromised patient with multiple myeloma, presenting as widespread ground-glass opacities and multiple necrotic subpleural nodules in both lungs on CT, which proved to be granulomatous PJP on percutaneous transthoracic needle biopsy.

Plasma- Cell Granuloma of Rib -Report of A Case- (늑골에 발생한 형질세포성 육아종 -1례 보고-)

  • Kim, Song-Myung;Lee, Ho-Youn
    • Journal of Chest Surgery
    • /
    • v.13 no.4
    • /
    • pp.507-511
    • /
    • 1980
  • Most cases of plasma-cell granuloma occur in adult skeleton system. They usually present as a single lesion, but multiple lesions are not uncommon. Roentgenographically, the lesions are lytic, sclerotic or mixed, but in the majority there is some degree of sclerosis. No specific etiologic agent is known, but it is postulated that the reaction may be associated with a variety of organisms of low-grade virulence. Certain organisms have long been known to produce predominantly plasmacytic infiltrate, notably spirochetes, mycobacteria and some exotic viruses. It is most important, however, that this entity, plasma-cell granuloma, be distinguished from multiple myeloma so those potentially life-threatening chemotherapeutic agents are not prescribed. Histologically, aggregates of chronic inflammatory cells are intermingled with the meets of plasma cells, and note the markedly thickened bone trabeculae in surrounding bone. We experienced a case of plasma-cell granuloma of right 7th. rib, occurring in 32 year old male and reported it with review of literatures.

  • PDF

A CASE REPORT OF PERIPHERAL GIANT CELL GRANULOMA (주변성 거대세포 육아종의 증례보고)

  • Kim Sung-Soo;Jung Yeon-Hwa;Cho Bong-Hae;Nah Kyung-Soo
    • Journal of Korean Academy of Oral and Maxillofacial Radiology
    • /
    • v.27 no.2
    • /
    • pp.127-133
    • /
    • 1997
  • The authors experienced one case of peripheral giant cell granuloma occurred at the gingiva of right maxillary molar in a 12-year-old male patient. The lesion showed amorphous calcification within soft tissue mass which made difficult to differentiate this lesion from peripheral ossifying fibroma and peripheral odontogenic fibroma clinically and radiographically. The final diagnosis was made histologically.

  • PDF