• Title/Summary/Keyword: 유효화 실험

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Analysis of Nutritional Composition and Effects of Yak-sun Tea Prescription from Oriental Medicinal Herbs for Serum Lipid Levels and Homocystein Content (한약자원을 이용한 약선차의 영양성분 분석 및 약선차의 섭취가 여대생의 혈청지질수준과 호모시스테인 농도에 미치는 효과)

  • Han, Jong-Hyun;Song, You-Jin;Park, Sung-Jin;Park, Sung-Hye
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.35 no.5
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    • pp.557-564
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    • 2006
  • This research was planned and executed to evaluate how the composition of Yak-sun (oriental diet therapy) can effect health conditions of people who are suffering from diet-related diseases like obesity and hyper lipidemia by taking Yak-sun in a form of nutritional supplement with our daily meals. We produced Yak-sun tea with $Ky\hat{a}lmy\hat{a}ngja$, Kamguk, $K\hat{u}m\hat{u}nhwa$, Ch'onkung and observed nutritional composition and evaluated how this tea effects on serum lipids and homocystein concentration by clinical practices. With this observation, we found out that this tea has significant effect on increasing of HDL-cholesterol, decreasing of LDL-cholesterol and homocysteine concentration, and we think that scientific and objective evaluation was done on the components of Yak-sun tea prescription. We concluded that we could apply the components not only in a form of tea, but also in other forms of various food. The information we received from this conclusion will be a basic information on how we can apply oriental medicinal resources into other food and will also be a stepping stone for medicinal herbs to step foot in the field of functional food research, which already draws sizable attention world-wide.

A Study on the Antigastritic Effects of Rheum Species Extracts and Their Active Components (대황 추출물의 항위염 작용과 유효성분에 관한 연구)

  • Hwang, In Young;Jeong, Choon Sik
    • Journal of Food Hygiene and Safety
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    • v.28 no.4
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    • pp.330-336
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    • 2013
  • Rheum tanguticum has long been used in oriental medicine as antipyretics, analgesics, anti-inflammation, aperient, hypertension medicine and medicine for skin disease. This study has investigated the effectiveness of defense for gastritis making use of Rheum tanguticum and its similar plants, Rumex cripus, Rheum officinale, Rhem palmatum and Rheum undulatum. Chysophanol, chrysophanol-8-O-glc, Desoxyrhaponticin desoxyrhaponti-genin, emodin, isorhaponticin, 2-methoxy-4-hydroxyanthraquinone-5-O-glc, physcion, pirace-tannol-3'-O-glc, resveratrol, rhaponticin and rhapontigenin are used as the components of Rheum tanguticum. In HCl ethanol-induced gastritis in rat, the most effective extract was 70 percent ethanol which is of Rheum tanguticum, showing the inhibition of 91.8 percent to the gastric lesions. 70% ethanol extract of Rhem palmatum and Rumex cripus shown inhibition of 75.6 percent and 73.2 percent, respectively. This effectiveness is considered as acid-neutralizing capacity, anti-H.pylori and anti-oxidant activity. 70% ethanol extract of Rheum tanguticum and its component, piracetannol-3'-O-glc exhibited higher free radical scavenging activity than others. These results suggest that Rheum species extracts and their active components could be utilized for the treatment of gastritis. Furthermore, these results are expected to contribute the standardization with objectivity and reliability for Rheum species, medicinal herbs. In addition, it can contribute to the prevention of indiscriminate distribution of imitation, and the rising rate of dependence on imports of medicinal herbs, and mixing prevention of low-quality goods.

Effects of Mockhyangjokisan and Haewooljoweetang on the Production of Collagen and the Regeneration of Liver Cells Damaged by Bile Duct Ligation and Dimethylnitrosamine (목향조기산(木香調氣散)과 해울조위탕(解鬱調胃湯)의 실험적(實驗的) 간경변(肝硬變)에 대(對)한 효과(效果))

  • Park, Young-Kweon;Kim, Kang-San;Kang, Byung-Ki;Jeon, Byung-Hun
    • The Journal of Korean Medicine
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    • v.18 no.1
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    • pp.480-498
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    • 1997
  • This study was to investigate the protective and anticirrhotic effects of Mockhyangjokisan and Haewooljoweetang on the liver cirrhosis or fibrosis induced by prolonged bile duct ligation; a new experimental model for cirrhosis and the intraperitoneal injection of dimethylnitrosamine in the rat. The development of fibrosis or cirrhosis and its inhibition by the two prescriptions were examined by the chemical analysis of AST, ALT, and hydroxyproline. The results obtained were as follows. 1. The increase of serum asparate aminotransferase induced by bile duct ligation was inhibited by the administration of Mockhyangjokisan and Haewooljoweetang extract. 2. The increase of serum alanine aminotransferase induced by bile duct ligation was inhibited by the administration of Mockhyangjokisan and Haewooljoweetang extract. 3. The increased level of serum AST and AL T induced by the intraperitoneal injection of dimethylnitrosamine was inhibited by the administration of Mockhyangjokisan and Haewooljoweetang extract. 4. The increasing level of hydroxyproline volume in the damaged liver tissues in the rat was decreased by the oral administration of Mockhyangjokisan and Haewooljoweetang extract. But there were no significant differences in the inhibition rate between the two experimental groups.

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Preparation of Nickel Hexacyanoferrate Ion Exchanger for Electrochemical Separation of Cations (양이온의 전기화학적 분리를 위한 페리시안니켈 이온교환체의 제조에 관한 연구)

  • Lee, Ji Hyun;Hwang, Young Gi
    • Applied Chemistry for Engineering
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    • v.21 no.1
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    • pp.52-57
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    • 2010
  • Although chemical sedimentation and ion exchange are usually applied to the treatment of heavy metal ions and radioactive cations, they have some serious disadvantages like a great consumption of chemicals, the disposal of valuable metals, and the secondary pollution of soil by the solid-waste. The advanced countries recently have studied the electrochemical ion exchange, combined electrochemical reduction and ion exchange, for the development of the alternative technique. This study has been performed to investigate the optimum condition for the preparation of the nickel hexacyanoferrate (NiHCNFe) which is an electrochemical ion exchanger. NiHCNFe film was deposited on the surface of nickel plate by chemical method or electrochemical method. The morphology and composition of NiHCNFe were observed by SEM and EDS, respectively. The peak current density of NiHCNFe was measured from the cyclic voltammograms of the continuous oxidation-reduction reaction in a parallel plane ion exchange electrode reactor. It was found that the chemical preparation method was better than the electrochemical method. The concentrated NiHCNFe was apparently deposited on nickel plate when dipping in the preparing solution for 118 h, especially. It also had a best durable performance as an ion exchange electrode.

A Study on Micro Clustering Technology for Breeding Pig Behavior Analysis (모돈 행동 특성 분석을 위한 마이크로 클러스터링 기술 연구)

  • Cho, Jinho;Oh, Jong-woo;Lee, DongHoon
    • Proceedings of the Korean Society for Agricultural Machinery Conference
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    • 2017.04a
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    • pp.165-165
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    • 2017
  • 모돈은 사육 특성상 제한된 파일롯 공간 안에 장시간 머물기 때문에 과중한 몸무게에 의한 지제 이상, 섭식 등의 불량, 수면상태의 불량 등을 지속적으로 관찰해야 하는 대상이다. 측면에 다수의 초음파 센서를 설치하여 기립의 상태 및 운동 시 몸체 궤적의 특성을 분석하여 종합적으로 모돈의 행동 특성을 정량화 하고자 하였다. 이 과정에서 계측 신호의 값을 대수적으로 비교하는 방식에 한계가 있음을 발견하였고, 이를 해결하고자 10 Hz/Ch 내외의 시계열 상대거리 궤적 신호를 주파수 도메인으로 변경하여 분석을 수행하였다. 일정 주파수에 집중되어 있는 주파수 값의 크기 변화(파워 스펙트럼 밀도)를 기준으로 모돈의 움직임의 정상 상태 유무 판별이 가능하였다. 단, 이러한 분석은 계측 데이터를 일괄 처리 방식으로 분석하는 방법으로 도출이 되었으므로, 계측과 정량 분석을 동시에 수행하기 위한 개선이 필요하였다. 계측 시스템에서 사용한 마이크로 프로세서는 Nucleo-446(STMelectronics, CA, USA)로 180 Mhz의 클럭 속도로 작동하나, 총 100 Hz 내외의 16비트 계측 신호에 대해 추가적으로 FFT 등의 주파수 변환 신호 처리를 수행하기에는 연산 능력이 부족하였다. 한편, 주파수 분석의 주기를 1분 단위로 할 경우 처리해야할 정보의 크기는 $100{\times}60{\times}5{\times}2Byte$ 이므로 1분 내에 해당 연산을 종료할 수 있는 추가의 연산 장치가 필요하였다. 계측과 주파수 도메인 변환 연산을 동시에 수행하기 위하여 1 Ghz의 연산능력을 가진 ARM A9 계열의 초소형 멀티코어 AP인 NanoPi Neo Air(Friendlyarm, Guangzhou, China)을 선정하였다. 4개의 코어를 각각 계측, Median 필터링, Smoothing 연산, FFT 분석에 사용하여 1분 단위, 2분 단위, 5분 단위의 주파수 분석을 동시에 수행하였다. 병렬 연산 라이브러리는 오픈 소스인 MPICH(www.mpich.org)를 이용하였다. 상대적으로 여유있는 자원을 보유하고 코어를 실시간으로 결정하여 다수의 모돈 개체 동시 모니터링을 위한 네트워크 연결 역할을 동시에 수행하도록 하였다. 1주일 내외의 요인 실험 수행 결과, 약 70 Mbyte의 데이터가 축적이 되었으며, 1분 단위, 2분 단위, 5분 단위의 주파수 도메인 변환 후 결과를 동시에 취득할 수 있었다. 일부 주파수 도메인 상의 파워 밀도 값이 모돈의 행동 특성에 분석에 유효한 정보를 제공함을 발견하였다. 모돈사 내 현장 보급이 가능한 초소형 AP와 멀티 코어 기반 병렬 처리 기법을 이용한 현장 진단 시스템 개발 연구를 지속적으로 수행할 것이다.

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Design and Implementation of Place Recommendation System based on Collaborative Filtering using Living Index (생활지수를 이용한 협업 필터링 기반 장소 추천 시스템의 설계 및 구현)

  • Lee, Ju-Oh;Lee, Hyung-Geol;Kim, Ah-Yeon;Heo, Seung-Yeon;Park, Woo-Jin;Ahn, Yong-Hak
    • Journal of the Korea Convergence Society
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    • v.11 no.8
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    • pp.23-31
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    • 2020
  • The need for personalized recommendation is growing due to convenient access and various types of items due to the development of information communication and smartphones. Weather and weather conditions have a great influence on the decision-making of users' places and activities. This weather information can increase users' satisfaction with recommendations. In this paper, we propose a collaborative filtering-based place recommendation system using living index by utilizing living index of users' location information on mobile platform to find users with similar propensity and to recommend places by predicting preferences for places. The proposed system consists of a weather module for analyzing and classifying users' weather, a recommendation module using collaborative filtering for place recommendations, and a management module for user preferences and post-management. Experiments have shown that the proposed system is valid in terms of the convergence of collaborative filtering algorithms and living indices and reflecting individual propensity.

Hypoglycemic Effects of Crude Extracts of Moutan Radicis Cortex (목단피 추출물의 혈당 강하 효과)

  • Park, Sun-Min;Jun, Doug-Wha;Park, Chun-Hee;Jang, Jin-Sun;Park, Seong-Kyu;Ko, Byoung-Seob;Kim, Bo-Jung;Choi, Soo-Bong
    • Korean Journal of Food Science and Technology
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    • v.36 no.3
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    • pp.472-477
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    • 2004
  • Hypoglycemie effect of Moutan Radicis Cortex (MRC) extract contained in Yukmijihuang-hwan was determined by investigating insulin-sensitizing and ${\alpha}-glucoamylase-suppressing$ actions. MRC was extracted with 70% ethanol, fractionated by XAD-4 column chromatography with mixture solvent of methanol and water, and utilized for hypoglycemic effect assay. Significant insulin sensitizing activities of MRC extracts were observed in 3T3-L1 adipocytes, giving MRC extracts with 1 ng/mL insulin reach glucose uptake level increased by 50 ng/mL of insulin alone. MRC methanol extracts of 20, 40, 60, and 80% suppressed ${\alpha}-glucoamylase$ activity in vitro. Peak serum glucose levels and area under curve were lower in Sprague Dawley male rats treated with MRC ethanol extract than those treated with cellulose in oral glucose tolerance test using 2 g dextrin/kg body weight. These data suggest MRC extracts contain effective insulin -sensitizing and ${\alpha}-glucoamylase-suppressing$ compounds for hypoglycemic activity.

Anti-Inflammatory Activity of Ethanol Extract of Sargassum miyabei Yendo via Inhibition of NF-κB and MAPK Activation (NF-κB와 MAPKs 활성 저해를 통한 미야베 모자반(Sargassum miyabei Yendo) 에탄올 추출물의 항염증 활성)

  • Kim, Min-Ji;Bae, Nan-Young;Kim, Koth-Bong-Woo-Ri;Park, Sun-Hee;Jang, Mi-Ran;Im, Moo-Hyeog;Ahn, Dong-Hyun
    • Microbiology and Biotechnology Letters
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    • v.44 no.4
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    • pp.442-451
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    • 2016
  • The aim of this study was to investigate the anti-inflammatory effect of Sargassum miyabei Yendo ethanol extract (SMYEE) using RAW 264.7 cells and croton oil-induced Balb/c mice. SMYEE inhibited the production of pro-inflammatory cytokines [interleukin (IL)-6, tumor necrosis factor $(TNF)-{\alpha}$, and $IL-1{\beta}$] and nitric oxide in lipopolysaccharide (LPS)-induced inflammatory response. In addition, SMYEE suppressed the expression of inducible nitric oxide, cyclooxygenase-2, and nuclear factor-kappa B. Further, SMYEE inhibited the expression of mitogen-activated protein kinases (MAPKs), such as extra cellular signal-regulated kinase 1/2, p38, and c-Jun N-terminal kinase. In ear edema test, edema formation in the SMYEE treatment was lower than that in the positive control and was similar to that in the prednisolone treatment group. Photomicrographs of mice ear tissue showed a reduction in dermal thickness and number of infiltrated mast cells. Therefore, our results indicate that SMYEE exerts an anti-inflammatory effect via inhibition of nuclear factor ${NF}-{\kappa}B$ and MAPK activation and can be used as a natural source of anti-inflammatory compounds.

Effect of Schmidt Number on Cohesive and Non-cohesive Sediment Suspension Modeling (점착성, 비점착성 부유사 모형에 대한 Schmidt 수의 영향)

  • Byun, Ji-Sun;Son, Minwoo
    • Journal of Korea Water Resources Association
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    • v.47 no.8
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    • pp.703-715
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    • 2014
  • This study aims to investigating the effect of Schmidt number (${\sigma}_c$) on sediment suspension and hydrodynamics calculation. The range of ${\sigma}_c$ is also studied based on the flux Richardson number ($Ri_f$) and gradient Richardson number ($Ri_g$). Numerical experiments are carried out by 1 dimensional vertical model. Both cohesive and non-cohesive sediments are tested under the conditions of pure current and oscillatory flow. The turbulence damping effect due to sediment suspension is examined considering ${\sigma}_c$ as a constant for the damping effect. The results of this study show the consistent effect of ${\sigma}_c$ on sediment suspension regardless of hydrodynamic condition. It is also found that the model overestimates the flow velocity and turbulent kinetic energy when the damping effect is not considered. Under the conditions of $Ri_f$ and $Ri_g$ causing density stratification, it is known that the vertical mixing of sediment is reasonably calculated in the range of ${\sigma}_c$ from 0.3 to 0.5.

A study on the preparation of 'Ginseng-leaf' tea (인삼엽(人蔘葉)을 이용(利用)한 다류제조(茶類製造)에 관한 연구(硏究))

  • Yang, Hee-Cheon;Lee, Suk-Young
    • Applied Biological Chemistry
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    • v.22 no.1
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    • pp.51-57
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    • 1979
  • The possibility of utilizing greet amount of by-product of ginseng (Panax ginseng C.A. meyer) plant-that is, production of ter from ginseng leaf, was studied and the results are summarized as follows: 1. Ginseng leaf contains more soluble matter than tea leaf (Thea sinensis) and the soluble matter is easily extracted by hot water. 2. Ginseng leaf has less tannin (2.2%) than yea leaf (7.89%). Therefore, it has less astringency than tea. 3. Vitamin C content of ginseng leaf is not compared with that of tea leaf. In fact, ginseng leaf contains Vitamin C $50{\sim}110$ times of tea leaf. 4. Ginseng leaf contains $5.7{\sim}8.5%$ glycoside (dammaranes) and the ratio of panaxadiol to panaxatriol is $0.54{\sim}0.75$ that is, panaxatriol contents is high. 5. For the acceptability of the product related with the soluble matter contents and color the method of extracting 2g of ginseng leaf product in 200ml of water for 3 minutes is recommended. 6. As a result of evaluating the flavor characteristics and effective components of the products, product D which is produced by the process of steaming, drying and roasting is considered to have the best quality.

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