• Title/Summary/Keyword: 유전체 분석

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Technology Trend of Microwave Dielectric Filters (마이크로파 유전체 필터 기술동향)

  • Kim, T.H.;Park, J.R.;Lee, S.J.;Lee, S.S.;Choy, T.G.
    • Electronics and Telecommunications Trends
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    • v.10 no.3 s.37
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    • pp.133-138
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    • 1995
  • 이동통신서비스의 보급확대에 따른 통신용단말기의 수요가 증가하고 있으나 단말기용 핵심부품은 일본 등 선진국에서 전량 수입에 의존하고 있다. 이중 마이크로파용 유전체를 이용한 필터의 경우 안테나 듀플렉서, RF 필터 등으로 이용되고 있으며, 소형화, 고기능화가 이루어지고 있다. 이 고에서는 이동통신용 핵심 부품인 이러한 유전체 필터의 소형화 추이 및 기술 동향을 살펴보고 국내 동향과 문제점 및 대책을 결론으로 제시하였다.

Properties of the gate dielectrics by thermal oxidation in ${N_2}O$ gas (${N_2}O$ 가스로 열산화된 게이트 유전체의 특성)

  • 김창일;장의구
    • Electrical & Electronic Materials
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    • v.6 no.1
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    • pp.55-62
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    • 1993
  • 수소 관련된 species를 포함하지 않고 자기제한특성으로 초박막 성장을 용이하게 제어할 수 있는 N$_{2}$O 가스 분위기에서 실리콘의 산화는 질화된 산화막의 재산화공정 보다 훨씬 간단한 공정이다. N$_{2}$O산화로 형성된 Si-SiO$_{2}$ 계면에서 nitrogen-rich층은 산화막 구조를 강화할 뿐만 아니라 게이트 유전체의 질을 개선하고 산화율을 감소시키는 산화제의 확산 장벽으로 작용한다. 초박막 oxynitride 게이트 유전체가 종래의 열산화 방법으로 제작되었고 oxynitride막의 특성이 AES와 I-V 특성 측정의 결과를 분석하여 연구하였다.

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A Polymorphism Analysis and Visualization Tool for Specific Variation Pattern Identification in Groups of Nucleotide Sequences (특정변화패턴 식별을 위한 염기서열 집단간의 다형성 분석 및 시각화 도구)

  • Lee, Il Seop;Lee, Keon Myung
    • Journal of Convergence for Information Technology
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    • v.8 no.6
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    • pp.201-207
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    • 2018
  • A genome contains all genetic information of an organism. Within a specific species, unique traits appear for each individual, which can be identified by analyzing nucleotide sequences. Many Genome-Wide Associations Studies have been carried out to find genetic associations and cause of diseases from slightly different base among the individuals. It is important to identify occurrence of slight variations for polymorphisms of individuals. In this paper, we introduce an analysis and visualization tool for specific variation pattern identification of polymorphisms in nucleotide sequences and show the validity of the tool by applying it to analyzing nucleotide sequences of subcultured pOka strain of varicella-zoster virus. The tool is expected to help efficiently explore allele frequency variations and genetic factors within a species.

An Efficient Parallelization Mechanism for Preprocessing of Genome Sequence Data on HPC environment (고성능 클러스터와 분산 병렬 파일 시스템을 이용한 유전체데이터 전처리 작업의 효율적인 병렬화 기법)

  • Byun, Eun-Kyu;Mun, Ji-hyeob;Kwak, Jae-Hyuck
    • Proceedings of the Korea Information Processing Society Conference
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    • 2018.10a
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    • pp.50-53
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    • 2018
  • 차세대 염기서열 분석법이 생성한 유전체 원시 데이터를 기존의 방식대로 하나의 서버에서 분석하기 위해서는 수십 시간이 필요할 수 있고 이러한 시간을 최대한 줄여야 하는 응급 상황도 존재한다. 따라서 본 연구에서는 고속의 네트워크로 연결되고 병렬 파일 시스템을 공유하는 서버 클러스터를 활용하여 분석 시간을 크게 단축 시킬 수 있는 유전체 데이터 분석의 전처리 프로세스의 병렬화 방법을 제안한다. 기존의 검증된 분석도구를 기반으로 프로세스의 병렬화, 데이터의 분배 및 병렬 병합 기법을 개발하였고 실험을 통해 성능을 향상 시킬 수 있음을 증명하였다.

Complete genome of a denitrifying Halioglobus sp. RR3-57 isolated from a seawater recirculating aquaculture system (순환여과양식시스템으로부터 분리된 Halioglobus sp. RR3-57의 유전체 분석)

  • Kim, Young-Sam;Noh, Eun Soo;Lee, Da-Eun;Kim, Kyoung-Ho
    • Korean Journal of Microbiology
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    • v.53 no.1
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    • pp.58-60
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    • 2017
  • Halioglobus sp. RR3-57 was isolated from a biofilter of a seawater recirculating aquaculture system and its complete genome sequence was obtained using the PacBio RS II platform. Two circular contigs were assembled and considered as a chromosome and a plasmid (size of 4,847,776 bp and 155,799 bp, and G+C content of 57.5% and 53.2%, respectively). Genomic analysis showed RR3-57 had 18 denitrification-related genes and an incomplete prophage.

Korea Brassica Genome Project: Current Status and Prospective (배추 유전체열구의 현황과 전망)

  • Choi, Su-Ryun;Park, Jee-Yong;Park, Beom-Seok;Kim, Ho-Il;Lim, Yong-Pyo
    • Journal of Plant Biotechnology
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    • v.33 no.3
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    • pp.153-160
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    • 2006
  • Brassica rape is an important species used as a vegetable, oil, and fodder worldwide. It is related phylogenically to Arabidopsis thaliana, which has already been fully sequenced as a model plant. The 'Multinational Brassica Genome Project (MBGP)'was launched by the international Brassica community with the aim of sequencing the whole genome of B. rapa in 2003 on account of its value and the fact that it has the smallest genome among the diploid Brassica. The genome study was carried out not only to know the structure of genome but also to understand the function and the evolution of the genes comprehensively. There are two mapping populations, over 1,000 molecular markers and a genetic map, 2 BAC libraries, physical map, a 22 cDHA libraries as suitable genomic materials for examining the genome of B. rapa ssp. pekinensis Chinese cabbage. As the first step for whole genome analysis, 220,000 BAC-end sequences of the KBrH and KBrB BAC library are achieved by cooperation of six countries. The results of BAC-end sequence analysis will provide a clue in understanding the structure of the genome of Brassica rapa by analyzing the gene sequence, annotation and abundant repetitive DHA. The second stage involves sequencing of the genetically mapped seed BACs and identifying the overlapping BACs for complete genome sequencing. Currently, the second stage is comprises of process genetic anchoring using communal populations and maps to identify more than 1,000 seed BACs based on a BAC-to-BAC strategy. For the initial sequencing, 629 seed BACs corresponding to the minimum tiling path onto Arabidopsis genome were selected and fully sequenced. These BACs are now anchoring to the genetic map using the development of SSR markers. This information will be useful for identifying near BAC clones with the seed BAC on a genome map. From the BAC sequences, it is revealed that the Brassica rapa genome has extensive triplication of the DNA segment coupled with variable gene losses and rearrangements within the segments. This article introduces the current status and prospective of Korea Brassica Genome Project and the bioinformatics tools possessed in each national team. In the near future, data of the genome will contribute to improving Brassicas for their economic use as well as in understanding the evolutional process.

The Application of Genome Research to Development of Aquaculture (양식산업에 발전을 위한 유전체 분석 기술 적용)

  • Lee, Seung Jae;Kim, Jinmu;Choi, Eunkyung;Jo, Euna;Cho, Minjoo;Park, Hyun
    • Journal of Marine Life Science
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    • v.6 no.2
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    • pp.47-57
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    • 2021
  • In the fishery industry, global aquaculture production has stagnated due to overfishing of aquatic products, restrictions between countries, and climate change. The aquaculture suggests the possibility of a blue revolution that can be expanded in a new way. The aquaculture industry now accounts for more than half of the fishery products from the sea as a raw material for seafood for human consumption. Various latest biological research methods are being applied for the development of a sustainable aquaculture industry. Genomics has made significant progress in recent years. Since the genome sequence of Atlantic cod was sequenced in 2011, the genomes of more species have been sequenced. The genome information is providing a more robust and productive knowledge base for the aquaculture industry, including breeding and breeding of superior traits, improving disease resistance quality, and optimizing aquaculture feed and feed methods. This review looked at the status of genome analysis technology and the current status of genome research of aquaculture species. The development of genome research technology and massive genomic information is important in solving the challenges of the aquaculture industry and will help sustainable fisheries and aquaculture.

Genetic Stability of the Plant-materials Induced in the Process of in vitro Organogenesis of Japanese Blood Grass (화본과 식물의 기내 기관분화 단계별 기관분화체의 유전적 안전성)

  • Ye-Jin Lee;In-Jin Kang;Chang-Hyu Bae
    • Proceedings of the Plant Resources Society of Korea Conference
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    • 2023.04a
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    • pp.35-35
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    • 2023
  • 안정적인 유묘의 확보는 스마트작물생산을 위한 공정육묘 생산에서도 중요하며, 기내배양시 유전적 안정성이 높은 유묘의 대량증식은 유묘생산과 공정육묘생산에서 중요한 과정이다. 기내배양시 배양과 정에서 존재하는 체세포영양계변이(somaclonal variation)라는 장벽을 제거하는 것이 중요하다. 본 연구에서는 화본과 식물인 홍띠(Imperata cylindrica ‘Rubra’)로부터 기관분화 단계별 재분화체를 작성하여 기관분화 시 기내재생체의 유전적 안정성을 조사하였다. ISSR 마커에 기반하여 유전적 변이성을 조사하고자 7종류 총 21개체의 기관분화 단계별 재분화체 및 재분화식물체에 대하여 분석한 결과, 유전적 다형성은 기관분화 단계별 재분화체 및 순화 재분화체에서 대조구인 모식물체(1.4%) 대비 같거나 높게 나타나서 재분화체에서 유전적 안정성이 다소 낮은 것으로 나타났다. 또한, Jaccard 계수(Jaccard coefficient)로 총 21개체들 간의 유전적 유사도 지수를 평가한 결과, 유전적 유사도 지수는 0.747~1.0 사이에 분포하며, 평균 0.868로 나타났다. ISSR 마커 밴드에 기반하여 평균연결법(Average linkage method)으로 군집 분석한 결과, 모든 개체는 유사도 지수 0.809 ~ 1.000 내에 분포하였다. 유전적 유사도 지수 0.809에서 2개 그룹으로 유집되었으며, 모식물체와 실내재배, 노지재배 재분화 녹색 식물체가 같은 그룹으로 분류되었다. 이상의 결과는 화본과 식물의 기내배양에서 기관분화 시 존재하는 체세포영양계변이에 대한 기초 정보를 제공해 준다. 이들 기관분화에 따른 기내재생체의 안정성에 대한 연구자료는 향후 기내식물의 안정적인 대량번식에 있어 유익한 배경을 제공해 줄 것이다.

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Surface Plasmon Modes Confined in the Gap Between Metal Nanowire and Dielectric Slab (유전체 판과 금속 나노선 사이에 구속된 표면 플라즈몬 모드)

  • Hahn, Chol-Oong;Oh, Cha-Hwan;Song, Seok-Ho
    • Korean Journal of Optics and Photonics
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    • v.22 no.6
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    • pp.269-275
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    • 2011
  • We propose a metal-dielectric hybrid waveguide structure consisting of a single metal nanowire placed on a flat dielectric slab. Mode size and propagation loss of the surface-plasmons confined in the metal-dielectric gap are compared with those of the complementary structure with a dielectric nanowire on a metal surface. In the case of the nanowire's diameter much smaller than the wavelength the two structures reveal quite different characteristics; the dielectric nanowire-on-metal has longer propagation distance, but only the metal nanowire-on-dielectric exhibits a mode size two fold smaller than the diffraction limit. The proposed hybrid structure may therefore be more suitable for realization of nanocavity lasers.

Development of Workbench for Analysis and Visualization of Whole Genome Sequence (전유전체(Whole gerlome) 서열 분석과 가시화를 위한 워크벤치 개발)

  • Choe, Jeong-Hyeon;Jin, Hui-Jeong;Kim, Cheol-Min;Jang, Cheol-Hun;Jo, Hwan-Gyu
    • The KIPS Transactions:PartA
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    • v.9A no.3
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    • pp.387-398
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    • 2002
  • As whole genome sequences of many organisms have been revealed by small-scale genome projects, the intensive research on individual genes and their functions has been performed. However on-memory algorithms are inefficient to analysis of whole genome sequences, since the size of individual whole genome is from several million base pairs to hundreds billion base pairs. In order to effectively manipulate the huge sequence data, it is necessary to use the indexed data structure for external memory. In this paper, we introduce a workbench system for analysis and visualization of whole genome sequence using string B-tree that is suitable for analysis of huge data. This system consists of two parts : analysis query part and visualization part. Query system supports various transactions such as sequence search, k-occurrence, and k-mer analysis. Visualization system helps biological scientist to easily understand whole structure and specificity by many kinds of visualization such as whole genome sequence, annotation, CGR (Chaos Game Representation), k-mer, and RWP (Random Walk Plot). One can find the relations among organisms, predict the genes in a genome, and research on the function of junk DNA using our workbench.