• Title/Summary/Keyword: 유의 감소

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Dependence of Channel Doping Concentration on Drain Induced Barrier Lowering for Asymmetric Double Gate MOSFET (비대칭 이중게이트 MOSFET에 대한 DIBL의 채널도핑농도 의존성)

  • Jung, Hakkee
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.20 no.4
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    • pp.805-810
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    • 2016
  • The dependence of drain induced barrier lowering(DIBL) is analyzed for doping concentration in channel of asymmetric double gate(DG) MOSFET. The DIBL, the important short channel effect, is described as lowering of source barrier height by drain voltage. The analytical potential distribution is derived from Poisson's equation to analyze the DIBL, and the DIBL is observed according to top/bottom gate oxide thickness and bottom gate voltage as well as channel doping concentration. As a results, the DIBL is significantly influenced by channel doping concentration. DIBL is significantly increased by doping concentration if channel length becomes under 25 nm. The deviation of DIBL is increasing with increase of oxide thickness. Top and bottom gate oxide thicknesses have relation of an inverse proportion to sustain constant DIBL regardless channel doping concentration. We also know the deviation of DIBL for doping concentration is changed according to bottom gate voltage.

Effects of Unripe Rubus coreanus Miquel Extract on Improvement of Lipid Metabolism in C57BL/6 Mice Fed a High-Cholesterol Diet (미숙과 복분자 열매 추출물이 고콜레스테롤 식이를 섭취시킨 C57BL/6 Mice의 지질대사 개선 효과)

  • Jung, Myung-A;Cho, Sook-Hyun;Lee, Sun Young;Kim, Ji Hye;Oh, Kyonyeo;Kim, Young-Suk;Yoo, GooSang;Lee, Dong-Wook;Kim, Sunoh
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.43 no.5
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    • pp.650-655
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    • 2014
  • Hypercholesterolemia is the presence of high levels of cholesterol in the blood, and it is regarded as a risk factor for cardiovascular disease due to the effects of cholesterol. The objective of this study was to investigate the effects of unripe Rubus coreanus Miquel (uRC) extract on lipid metabolism in hypercholesterolemic mice fed a high cholesterol diet (HC). uRC 50 (unripe R. coreanus 5% ethanol extract 50 mg/kg/day), uRC 100 (unripe R. coreanus 5% ethanol extract 100 mg/kg/day), uRC 300 (unripe R. coreanus 5% ethanol extract 300 mg/kg/day), and BO (borage seed oil containing minimum of 20% ${\gamma}$-linolenic acid 30 mg/kg/day) were orally administered for 60 days after HC. Oral administration of uRC 50, uRC 100, uRC 300, and BO significantly reduced serum total-cholesterol, triglyceride, LDL-cholesterol, glutamic oxaloacetic transaminase, glutamic pyruvic transaminase, atherogenic index, and cardiac risk factor levels. Similarly, uRC treatment elevated serum HDL-cholesterol levels. These results suggest that unripe R. coreanus extract could be established as a functional food for the improvement of lipid metabolism.

The Effects of Forest Bathing on Social Psychological and Job Stress (삼림욕이 사회 심리적 및 직무적 스트레스에 미친 영향)

  • Sin, Bangsik;Lee, Keun Kwang
    • Journal of Naturopathy
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    • v.7 no.2
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    • pp.51-62
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    • 2018
  • Purpose: The purpose of this study was to investigate the changes of stress and cumulative stress in 49 people and the changes of job stress, socio-psychological stress and anxiety relief levels by conducting a survey of 85 people after Gyorae forest bathing. Methods: The level of stress was measured using the uBioMacpa, and questionnaire was conducted to derive the data. Results: In the stress level after the forest bath, the control group showed no significant and the experimental group showed a significant decrease in the bathing (p<.043). In the cumulative stress change, the control group showed no significant difference after the bathing, but experimental group decreased significantly (p<.02), and in the variance analysis, there was a significant difference between the groups, and also between the group and the before and after tests (p<.002). In the questionnaire about job stress, there was no significant difference in physical environment and job demand. Overall, in the case of job stress, there was a significant decrease (p<.001). Job autonomy, relationship conflict, organizational unfairness, inadequate compensation, and workplace culture also had a significant decrease in stress (p<.001). The social psychological stress was significantly decreased after bathing (p<.001). The state anxiety decreased significantly (p<.001) after forest bathing. Conclusions: After the forest bathing in the Gyorae forest, the stress and anxiety are both reduced and significant, providing basic information that is very helpful as a natural healing place for stress relief.

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Quality characteristics of sponge cake with buckwheat powder (메밀가루를 첨가한 스펀지 케이크의 품질특성)

  • Lee, Seon-Ho;Bae, Jong-Ho
    • Food Science and Preservation
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    • v.22 no.2
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    • pp.204-210
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    • 2015
  • This study investigated the quality characteristics of sponge cake by introduction of buckwheat powder (BP). Cake batter was prepared by substituting wheat flour with an equivalent amount of BP based on weight. Sponge cakes were prepared with different amounts of BP (0, 10, 20, and 30%, respectively). Their physicochemical and sensory properties were tested. The specific gravity was not affected by the addition of BP (10~30%) (p<0.05). The lightness (L value) and yellowness (b value) of the crumb significantly decreased with the increase in the BP contents (p<0.05), whereas the redness (a value) increased (p<0.05). As the increase in the amount of BP addition, the hardness, cake volume (mL), baking loss rate (%), and specific volume (mL/g) significantly decreased (p<0.05). On the contrary, the cake weight increased. In the sensory evaluation, no significant differences in terms of color, taste, texture, flavor, and overall acceptance were observed among the different amout of BP addition (0~20%) (p<0.05). Overall, the sponge cake prepared with the addition of 20% BP was recommended to use due to its advantages in functional property.

The Effect of Aerobic Exercise on Immune Function, Physical Fitness and Fat mass in Middle-Aged Women (유산소성 운동이 중년여성의 면역기능과 체력 및 체지방률에 미치는 영향)

  • 한성섭
    • Journal of Life Science
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    • v.12 no.5
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    • pp.622-631
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    • 2002
  • The purpose of this study is to analyze the effects of aerobic exercise on immune function, physical fitness and fat mass in middle-aged women. Twenty subjects were divided into two groups : experimental group(N:10) and control group(N:10). Experimental subjects were under the exercise conditions to perform the aerobic exercise using the movement of dance-sports with intensity of 60~80% HRmax for 60 min/day, 3 times/week during 12 weeks. After the aerobic exercise, the numbers of neutrophil, Iymphocyte, eosinophil, basophil, 73, 74 and B4 were significantly different. Crip-strength and sit-up ability significantly improved and all so weight and fat mass decreased on experimental group. Therefore, the aerobic exercise using the movement of dance-sports applying to middle-aged women would contribute them healthy life and prevention of chronic disease.

Effects of Cordyceps Militaris Mycelia(CMM) oral administration and Herbal Acupuncture at Shinsu(BL23), Tae-gye(K3) on Expression of Aquaporin-2 Protein Water Channels in the Kidney and the Renal Function in Rats with Renal Failure by Uninephrectomy (신유(腎兪),태계(太谿)의 동충하초(冬蟲夏草) 약침(藥鍼)과 경구(經口) 투여(投與)가 좌측 신장(腎臟) 제거 백서(白鼠)에 대한 신장(腎臟) Aquaporin-2 단백(蛋白) 발현(發現)과 신장기능(腎臟機能)에 미치는 영향(影響))

  • Kim, Jae-hong;Yoon, Dae-hwan;Na, Chang-su;Cho, Myung-rae;Yoon, Yeo-choong;Chae, Wu-suk
    • Journal of Acupuncture Research
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    • v.22 no.1
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    • pp.61-75
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    • 2005
  • Objective : The purpose of this study is to arrange the literature about a acupuncture therapy on the knee rheumatoid arthritis. Methods : We arrange fifty kinds of literature about a acupuncture therapy of knee joint, knee arthritis, Results : Acupucture point at G30, G34, S36, LI11, B4O, G39, G38, LI4 used freaquently for the acupuncture therapy Conclusion : B, G, S, Sp of merdians used frequently for the acupuncture therapy.

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Influence of Prosthesis Size on Change in Left Ventricular Hypertrophy Following Aortic Valve Replacement (대동맥판막협착증 환자에서 판막치환 후 좌심실 심근비후의 변화에 대한 판막크기의 영향)

  • 이희성;지현근;김건일;홍기우;신윤철
    • Journal of Chest Surgery
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    • v.34 no.1
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    • pp.57-63
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    • 2001
  • 배경: 대동맥판막협착증 환자는 판막질환으로 인한 만성적인 후부하의 증가에 대한 보상성 좌심실 심근비후가 일어나게 된다. 대동맥 판막 치환 후 좌심실 심근 비후의 감소가 이루어지는 것으로 알려져 있으나 21mm이하의 작은 인공판막으로 치환시 좌심실 심근 변화에 대해 논란이 있다. 대상 및 방법: 1994년 9월부터 1998년 7월까지 한림대학교 강동성심병원 흉부외과에서 대동맥판막협착증으로 진단받고 판막치환술을 시행한 20명을 대상으로 하였다. 환자는 남녀 각각 13명, 7명이며 평균나이 61$\pm$13.8세 체표면적은 평균 1.57$\pm$0.14m$m^2$이었다. 환자의 추적관찰은 수술 전, 수술 후 초기(평균 10.4일) 및 수술 후 만기(평균 29.9개월)에 심초음파로 시행하였다. 환자들은 사용된 판막에 따라 2개의 군(1군;21mm 이하, 2군;23mm이상)으로 나누었다. 결과: 모든 군에서 NYHA Functional class의 유의한 감소가 있었다. 좌심실 구추률은 수술 전후 1군은 유의한 차이가 없었으나 2군에서는 유의한 차이가 있었다. 그러나 수술 전 좌심실 구출률이 2군에서 1군에 비해 유의하게 감소되어 있었다(p=0.044). 좌심실근량지수는 1군은 수술후 초기에 유의한 감소가 없었으나 수술후 만기에는 유의한 감소를 보여주었다. 그러나 2군은 수술후 초기와 만기에 모두 유의한 감소를 보여주었다. 결론: 21 mm이하 군과 23 mm이상 군 모두 임상적 호전이 있었다. 그러나 19 mm판막군이 2례로 적어 19 mm 판막의 사용시 환자의 나이와 체표면적, 운동량을 고려하여 신중한 판막선택이 고려된다.

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Effects of Different Types of Dietary Fat on Muscle Atrophy According to Muscle Fiber Types and PPAR${\delta}$ Expression in Hindlimb-Immobilized Rats (지방의 종류가 다른 식이의 섭취가 하지고정 흰 쥐의 근 섬유별 근 위축과 PPAR${\delta}$ 활성에 미치는 영향)

  • Lee, Ho-Uk;Park, Mi-Na;Lee, Yeon-Sook
    • Journal of Nutrition and Health
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    • v.44 no.5
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    • pp.355-365
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    • 2011
  • This study investigated how dietary fat affects muscle atrophy and lipid metabolism in various muscles during hindlimb immobilization in rats. Twenty-four male Sprague?Dawley rats had their left hindlimb immobilized and were divided into four groups by dietary fat content and composition. The contralateral hindlimb (control) was compared with the immobilized limb in all dietary groups. Rats (n = 6/group) were fed a 4% corn oil diet (CO), 2.6% corn oil + 1.4% fish oil diet (FO), 30% corn oil diet (HCO), or a 30% beef tallow diet (HBT)after their hind limbs were immobilized for 10 days. Data were collected for the gastrocnemius, plantaris and soleus muscles. Muscle atrophy was induced significantly after 10 days of hindlimb immobilization, resulting in significantly decreased muscle mass and total muscle protein content. The protein levels of peroxisome proliferator activated receptor ${\delta}$ (PPAR${\delta}$) in the plantaris, gastrocnemius, and soleus increased following hindlimb immobilization irrespective of dietary fat intake. Interestingly, the PPAR${\delta}$ mRNA level in the plantaris decreased significantly in all groups and that in the FO group was lower than that in the other groups. The soleus PPAR${\delta}$ mRNA level decreased significantly following hindlimb immobilization in the FO group only. Muscle carnitine palmitoyl transferase 1 (mCPT1) mRNA level was not affected by hindlimb immobilization. However, the mCPT1 mRNA level in the FO group was significantly lower in the plantaris but higher in the soleus than that in the other groups. The pyruvate dehydrogenase kinase 4 (PDK4) mRNA level in the plantaris decreased significantly, whereas that in the soleus increased significantly following hindlimb immobilization. The plantaris, but not soleus, PDK4 mRNA level was significantly higher in the FO group than that in the CO group. The increased PPAR${\delta}$ protein level following hindlimb immobilization may have suppressed triglyceride accumulation in muscles and different types of dietary fat may have differentially affected muscle atrophy according to muscle type. Our results suggest that ${\omega}$-3 polyunsaturated fatty acids may suppress muscle atrophy and lipid accumulation by positively affecting the expression level and activity of PPAR${\delta}$ and PPAR${\delta}$-related enzymes, which are supposed to play an important role in muscle lipid metabolism.

The Effects of Training on Body Fat and Blood Lipid (운동효과가 체지방 및 혈중 지질에 미치는 영향)

  • 최현숙;안응남
    • Journal of Life Science
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    • v.8 no.5
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    • pp.563-570
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    • 1998
  • The seven (7) housewives were used as subjects at three times per weeks for twelve (12) weeks in order to find out the effects of aerobic exercise and weight training on body composition and blood lipid. Each subject's weight, lean body mass, percent body fat, BMI and blood lipid were measured immediately after the training and the results compared with the same prior to exercises were obtained as follows ; 1. The weight and percent body fat of the subjects were slightly but not significantly decreased, however the lean body mass following training was significantly increased with 1.3 %. BMI S RBW were also not significantly decreased. 2. Calory intake was 1929.9 cal before the training and 1896.0 cal after the training, which doesn't shows much difference. 3. The blood lipid such as TC and LDL-C were a little increased after the training, but HDL-C shows significant increase of 22.7 %, and HDL-C/TC was significantly increased with 13.2 % (p<.05 ) as well. However, TG shows significant decrease (p<.05 ).

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Development of morning bread fortified citrus peels powders and its evaluation of biological activity by human trial (귤피가루를 첨가한 모닝빵 개발 및 인체시험을 통한 생리활성 효과 평가)

  • Lee, Ha-Neul;Park, Tae-Sun;Yu, Ok-Kyeong;Byun, Moon-Sun;Cha, Youn-Soo
    • Journal of Nutrition and Health
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    • v.49 no.3
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    • pp.144-152
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    • 2016
  • Purpose: This study was conducted in order to develop morning bread using powdered citrus peels and to examine the effect of its several biological activities for 12 weeks in overweight adults ($$BMI{\geq_-}23$$) living in dormitories of Chonbuk National University. Methods: Control bread was prepared using the same formula except for replacing the wheat flour with 3% citrus peel powder. Subjects were classified according to two groups: Intake group of 3% citrus peel powder fortified morning bread (n = 30) and general morning bread (n = 30). Results: The results of our study showed no significant effects of citrus peel powdered morning bread on anthropometric indices and biochemical characteristics among overweight adults. Despite the slight reduction in total-cholesterol, LDL-cholesterol, GOT, and GPT (p < 0.05), no significant differences in changes of these values were observed between the two groups. Conclusion: The short duration of our intervention might have resulted in the lack of any significant effect. Therefore, conduct of further studies with longer duration is warranted in order that the results from this study can be utilized as a basis for the development of food products with citrus peel powder.