• The Journal of Korean Society for School & Community Health Education
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• v.25 no.2
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• pp.45-57
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• 2024

Objectives: The purpose of this study is to determine the impact of artificial menopause on the diagnosis of thyroid cancer, breast cancer, and cervical cancer, and to provide basic data for cancer prevention and early diagnosis in women. Methods: Analysis was conducted using raw data from the 2011-2020 National Health and Nutrition Examination Survey. Among the 79,262 people surveyed in the 2011-2020 National Health and Nutrition Examination Survey, 10,207 people were selected as the final research subjects, excluding men, those under 18 years old, those over 80 years old, those who did not participate in the health survey, those with missing data, and those who were not in menopause. Among them, 248 people were diagnosed with thyroid cancer (2.7%), 225 people were diagnosed with breast cancer (2.5%), and 143 people were diagnosed with cervical cancer (21.5%). Results: First, there appeared to be differences between the thyroid cancer diagnosed group and the non-diagnosed group depending on educational level, childbirth experience, and menopause type. Second, there appeared to be differences between the breast cancer diagnosis group and the non-diagnosis group depending on educational level, menopause age, pregnancy experience, childbirth experience, subjective health status, and menopause type. Third, there appeared to be differences between the cervical cancer diagnosis group and the non-diagnosis group depending on menopause age, subjective health status, and menopause type. Fourth, compared to natural menopause, in the case of artificial menopause, the diagnosis probability of women increased by 2.010 times for thyroid cancer, 3.872 times for breast cancer, and 14.902 times for cervical cancer. Conclusion: For thyroid cancer, breast cancer, and cervical cancer, the probability of cancer diagnosis increases in the case of artificial menopause compared to natural menopause, so it is considered important to avoid experiencing artificial menopause to prevent cancer.

• Journal of Fashion Business
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• v.15 no.1
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• pp.63-79
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• 2011

This study examines the relationship between breast shape and brassiere construction through the comparative analysis of brassiere pattern on the breast shape. This researcher drew the brassiere pattern of developing a pre-study for Chinese female adults according to average size based on the four breast shapes. And then we measures brassiere pattern size and comparatively analyzes breast between size and shape. Comparative analysis results of brassiere patterns are verified differences of size and shape on the breast shape. Above all an angle of cup dart showed remarkable differences on the breast shape. An angle of cup dart isn't proportioned to breast size. An angle of cup dart for cone shape is bigger than dome shape. Because cone shape breast is protruded center part but dome shape breast have a shape of smooth curve like a half globe. So an angle of a cone shape breast cup dart is determined bigger than dome shape breast. For increasing the uplift effect of brassiere, brassiere pattern is different on the breast shape. And a brassiere pattern need different drawing methods about the angle of cup dart, breast inner side diameter, slope and so on. This study has an important significance that it established a mechanical relationship of breast shape and brassiere pattern.

• Archives of Hand and Microsurgery
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• v.23 no.4
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• pp.281-289
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• 2018

Purpose: Preoperative surgical planning utilizing computed tomography angiography (CTA) has now become a routine in many practices. We analyzed the course of the deep inferior epigastric artery (DIEA) and its perforators (DIEP) that would either facilitate or hinder flap dissection based on CTA to aid surgical planning. Methods: The 115 consecutive patients who underwent abdominally based free flap breast reconstruction were enrolled in this prospective study. DIEA/P courses were categorized mainly according to their intramuscular courses and their incidences were investigated. Results: A total of 425 perforators were identified preoperatively on the CTA, with an average number of 3.7 distinctly visualized in the entire flap territory. Eighty-nine perforators (20.9%) had a favorable (less than 1 cm intramuscular course) pattern, namely long submuscular (34.8% of the patients), long subfascial (15.6%), and total circummuscular (13.9%). Overall 56.5% of the patients had at least one favorable DIEA/P. On the other hand, absence of DIEA and absence of adequate (>1 mm) DIEP was reported in 3 and 8 hemiabdomen. Conclusion: Preoperative CTA evaluation of DIEA/P can be used to identify favorable as well as unfavorable courses for dissection to aid surgical planning.

• Journal of the Korean Society of Radiology
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• v.81 no.4
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• pp.886-898
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• 2020

Purpose The purpose of our study was to evaluate digital breast tomosynthesis as a breast cancer screening modality for women with gynecologic cancer. Materials and Methods This retrospective study included patients with underlying gynecologic malignancies who underwent screening digital breast tomosynthesis for breast cancer. The cancer detection rate, recall rate, sensitivity, specificity, and positive predictive value (PPV) were calculated. PPV1 was defined as the percentage of all positive screening exams that have a tissue diagnosis of cancer within a year. PPV2 was defined as the percentage of all diagnostic exams (and Breast Imaging Reporting and Data System category 4, 5 from screening setting) with a recommendation for tissue diagnosis that have cancer within a year. PPV3 was defined as the percentage of all known biopsies actually performed that resulted in a tissue diagnosis of cancer within the year. For each case of screen-detected cancer, we analyzed the age, type of underlying gynecologic malignancy, breast density, imaging features, final Breast Imaging Reporting and Data System assessment, histologic type, T and N stages, molecular subtype, and Ki-67 index. Results Among 508 patients, 7 with breast cancer were identified after a positive result. The cancer detection rate was 13.8 per 1000 screening exams, and the recall rate was 17.9%. The sensitivity was 100%, and the specificity was 83.2%. The false negative rate was 0 per 1000 exams. The PPV1, PPV2, and PPV3 were 7.7, 31.8, and 31.8, respectively. Conclusion Digital breast tomosynthesis may be a promising breast cancer screening modality for women with gynecologic cancer, based on the high cancer detection rate, high sensitivity, high PPV, and high detection rate of early-stage cancer observed in our study.

• Journal of Preventive Medicine and Public Health
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• v.31 no.1 s.60
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• pp.15-26
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• 1998

p53 is the most frequently mutated gene in female breast cancer tissues and the prognosis of breast cancer could be changed by mutation of the gene. This study was performed to examine risk factors for breast cancer subtypes classified by p53 mutation and to investigate the roles of p53 gene mutation in carcinogenesis of breast cancer. The study subjects were 81 breast cancer patients and 121 controls who were matched to cases 1:1 or 1:2 age, residence, education level and menopausal status. All the subjects were interviewed by a well-trained nurse with standardized questionnaire on reproductive factors, and wire asked to fill the self-administrative food frequency questionnaire. p53 gene mutation in the cancer tissue was screened using polymerase chain reaction (PCR)-single strand conformational polymorphism (SSCP) method. Mutation type was identified by direct sequencing of the exon of which mobility shift was observed in SSCP analysis. Mutations were detected in p53 gene of 25 breast cancer tissues. By direct sequencing, base substitutions were found in 20 cancer tissues (10 transition and 10 transversion), and frame shift mutations in 5 (4 insertions and 1 deletion). For the whole cases and controls, risk of breast cancer incidence decreased when the parity increased, and increased when intake amount of total calory, fat, or protein increased. Eat and protein were statistically significant risk factors for breast cancer with p53 mutation. For breast cancer without p53 mutation, protein intake was the only significant dietary factor. These results suggest that causes of p53 positive breast lancer would be different from those of p53 negative cancer, and that dietary factors or related hormonal factors induce mutation of p53, which may be the first step of breast cancer development or a promoter following some unidentified genetic mutations.

• Journal of Life Science
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• v.18 no.7
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• pp.968-973
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• 2008

The study was to provide basic data and to examine the effect of combined exercise for 12 months on functional fitness and bone mineral density (BMD) in breast cancer survivors. The subjects of this study were 40 to 60-year-old married women (N=24) who finished their treatments chemotherapy and radiation therapy. They were divided into two groups that exercise group and exercise with alendronate group. Eighteen (T-score=$-2.2{\pm}0.8$) of the 24 women who were diagnosed osteopenia (N=15) and osteoporosis (N=3), participated in combined exercise (EG). The other six (T-score=$-4.6{\pm}0.9$) women who were diagnosed as osteoporosis (EDG), participated in the combined exercise program with osteoporosis drug (Alendronate 70 mg/w). The result of the analysis was as follows: Twelve months after, the participants (N=24) had a significant increase of the items such as sit and reach ups, grip strength (R and L) and sit ups test of functional fitness in the periods. In body composition, FM (fat mass) had significant decrease in periods. In the comparison of BMD, EG (N=18) had no change, while EDG (N=6) had significant improvement in L1, T12 and T-score after 12months. Consequently, complex exercise program (Hatha yoga, elastic band, gym ball) had positive effect on functional fitness and bone mineral density. We suggest that complex exercise program can be applied as recovery program after breast cancer surgery. Further research needs various and repetitive studies from more different targets or methods in the exercise program for its improvement.

• Radiation Oncology Journal
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• v.15 no.4
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• pp.331-337
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• 1997

Purpose : To evaluate our experience in the breast-conserving treatment for early breast cancer with special regard to recurrence Pattern and related risk factors. Materials and Method :Two hundred and sixteen patients with AJC stage 1and 11 breast cancer who received breast conserving treatment between January 1991 and December 1994 were evaluated A9e distribution ranged from 23-80 year old with a median a9e of 44. One hundred and seventeen Patients had 71 lesions and 99 Patients had 72 lesions. Axillary lymph nodes were involved in 73 patients. All patients received a breast conserving surgery (wide excision to quadrantectomy) and axillary node dissection followed by radiotherapy. Ninety six patients received chemotherapy before or after radiotherapy. Results : During the follow-up period (3-60 months, median 30 months), local recurrences were noted in six Patients (true: 3, elsewhere; 1, skin: 2). Sixteen patients developed distant metastases as the first sign of recurrence at 8-38 months (median 20 months) after surgery. Among them, three patients simultaneously developed local recurrence with distant metastases. Contralateral breast cancer developed in one Patient and non-mammary cancers developed in three patients. The actuarial 5 year survival rate was $88.4\%\;(stage\;I\;96.7\%,\;stage\;IIa\;95.2\%,\;stage\;IIb\;69.9\%)$. Age, I stage, number of involved axillary lymph nodes. and AJC stage were risk factors for distant metastases in univariate analysis. In the multivariate analysis, the number of involved axillary lymph nodes was the most significant risk factor for metastases. Conclusion : Local recurrence was not common in the early years after radiotherapy. Distant metastases occurred at a steady rate during the first three years and was more common in the Patients with larger tumors, higher number of involved axillary nodes, and younger age.

• Fashion & Textile Research Journal
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• v.19 no.6
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• pp.786-794
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• 2017

The purpose of this study is to analyze and classify breast shape of women aged 11~15 using 3D body scan data. In this study, 250 women's body scans were selected from the 6th Size Korea dataset, and 30 items from each of the scan were measured using RapidForm XOR 3 program. The principal component analysis and cluster analysis were conducted using statistical program SPSS 17.0. The five principal components were identified; breast drooping and breast capacity, size from chest to under bust area, breast protrusion, breast height, and under breast angle & outer distance of breast. As the results of cluster analysis, woman's breast types were classified into four types. The breast type 1 was protrusion type (25.1%) which is considered as the breast maturity stage. The breast type 2 had the most drooped breast covering a large area (20.2%). The breast type 3 had the least prominent breast with a highest nipple point, which was considered as the early breast development stage (38.9%). The breast type 4 had the obesity of the chest and breast circumferences with the slightly prominent and the least drooped breast (15.8%). This study can provide fundamental information to develop sizing system and brassiere pattern for junior girls.

• Journal of the Korean Society of Clothing and Textiles
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• v.36 no.8
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• pp.791-801
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• 2012

We performed an assessment of wearing, purchasing, satisfaction, and the fit of brassieres according to body and breast type for college women to provide basic data on the manufacture of an ergonomic brassiere. The classifications of domed and conical breast type or projecting and conical breast type were unclear. Flat breast were dissatisfied with the shape of small and flat, and drooping breast were dissatisfied with the shape of big, projected, and drooping. In purchasing a brassiere, the majority of subjects were ignorant of their brassiere size, and over 80% of the subjects bought a brassiere without trying it on. Over 50% of those surveyed said they found it difficult to buy a well-fitted brassiere, particularly for the flat and drooping breast type. Over 70% of those surveyed wore a brassiere of 3/4 cup size, the slim body type wore a brassiere of 1/2 cup size; however, the obese body type wore a brassiere of full-cup size. The flat-breast or slim-body wore a brassiere of a thick pad type but projecting-breast or drooping breast wore brassiere of a thin pad type. Many of the subjects wore an unfitted brassiere in cup size and under bust size. In the classification of breast type, there were slight differences between the breast type that they recognized and the breast type that they were shown. There were distinctions in function, satisfaction, and fitness based on breast type. Therefore, the development of an ergonomic brassiere should considered the characteristics of breast type for fitness and comfort.

• Journal of Fashion Business
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• v.20 no.4
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• pp.15-35
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• 2016

The purpose of this study was to develop brassiere pattern designed to fit the breast shapes based on ESMOD pattern. It has three quarters cup round shape and also consists of three parts; upper cup, lower cup, and wings. Breast types are classified into five shapes; ideal breast, flat breast, upper developed breast, lower developed breast, and projecting breast. Two subjects for each breast type wore the brassiere, and they evaluated the appearance and wearing twice. Type I for research pattern designed to fit into the breast shape reflecting details of breast size were assessed as superior to the divided commercial type. However, wings' tightness of Type I for research pattern brassiere was high. Thus, to improve wearing satisfaction, extra was added to wing. Based on the results of wearing experiments of Type I for research, we adjusted and modified Type II for research pattern. Subsequently, its appearance and wearing were evaluated, in order to be improved. For upper developed breast pattern, we extended the length of lower part to balance upper and lower part, as the upper part was somewhat long. The lower developed breast has the closest feature to the ideal breast, suggestive that implies it does not require much improvement Projecting breast pattern has minimal space in the lower part, so we added the support to lift them to be similar to the ideal breasts. For all the breast shapes, we reduced the wings' tightness from 8% to 7% so that we could extend the length of the wings.