• Journal of Gastric Cancer
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• v.5 no.2
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• pp.79-88
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• 2005

Quality assurance may be defined as the complete set of systemic actions that is required to achieve a better treatment result by standardizing treatment and by using various audit programs. In general, application of a quality assurance program in surgery is considered to be more difficult than it is in chemotherapy or radiotherapy. However, recently, the importance of quality assurance in the surgical field has been emphasized in clinical trials comparing different surgical procedures and evaluating the role of postoperative adjuvant therapy. In the case of gastric cancer surgery, excellent quality assurance programs have rarely been applied in most large prospective clinical trials. Although the quality assurance in Dutch trial was conducted very systemically and strictly, the situation is quite different from ours. On the other hand, several quality assurance programs in Japanese trials comparing D2 and D2 plus para-arotic lymph node dissection seem to be applicable to Korean clinical trials. Several factors, including selection of appropriate surgeons based on personal experience and annual number of operations, standardization of surgical procedures by education and consensus, development of a unified database program, application of standardized perioperative management, and standardization of pathologic examination, are required to guarantee a successful multi-institutional prospective clinical trial. In contrast, one needs to realize that protocols that are too strict and sophisticated can make the enrollment of patients and surgeons more difficult and can promote protocol violation during the clinical trials. (J Korean Gastric Cancer Assoc 2005;5:79-88)

• Cartoon and Animation Studies
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• s.36
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• pp.167-187
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• 2014

Animation-related films and game industries have been expanding their markets rapidly responding to sharply increasing public demand. The production processes of major studios are getting more and more specialized and detailed. Therefore, they feel burden to manage and maintain as the HR and physical sizes are getting greater. So, independent studios which perform partial processes of the works are increasing over North America and Europe. Specialized studios build previous functions and related business models. They are expanding their areas. Therefore, this study targeted studios specialized in digital concept art in free production step. The characteristics of such studios were analyzed. To this end, first definitions of digital concept art concepts and functional & artistic features of entire production, and their application to business were deliberated through documents and online. Based on the results, the features of 'concept art service', 'self-brand business/ communication', and 'education service' were drawn. Second, based on it, targeting three con cept art studios such as Atomhawk (UK), FengZhu Design (Singapore), and Studio Gage (Korea), case research was done. Comparative analysis for the cases was conducted. It turned out that concept art studio s lead new market demand through active business strategies such as related contents development, marketing, etc. based on specialization. This research is significant to understand global trend of newly establishing specialized studios market and suggest reference data to improve prospective domestic specialized studios competitiveness.

• Journal of the Korean earth science society
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• v.44 no.1
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• pp.1-12
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• 2023

Oceanic wind waves have been recognized as one of the important indicators of global warming and climate change. It is necessary to study the spatial and temporal variability of significant wave height (SWH) and wave direction in the Yellow Sea and a part of the East China Sea, which is directly affected by the East Asian monsoon and climate change. In this study, the spatial and temporal variability including seasonal and interannual variability of SWH and wave direction in the Yellow Sea and East China Sea were analyzed using European Center for Medium-Range Weather Forecasts (ECMWF) Reanalysis 5 (ERA5) data. Prior to analyzing the variability of SWH and wave direction using the model reanalysis, the accuracy was verified through comparison with SWH and wave direction measurements from Ieodo Ocean Science Station (I-ORS). The mean SWH ranged from 0.3 to 1.6 m, and was higher in the south than in the north and higher in the center of the Yellow Sea than in the coast. The standard deviation of the SWH also showed a pattern similar to the mean. In the Yellow Sea, SWH and wave direction showed clear seasonal variability. SWH was generally highest in winter and lowest in late spring or early summer. Due to the influence of the monsoon, the wave direction propagated mainly to the south in winter and to the north in summer. The seasonal variability of SWH showed predominant interannual variability with strong variability of annual amplitudes due to the influence of typhoons in summer.

• Journal of Pharmaceutical Investigation
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• v.30 no.4
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• pp.299-307
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• 2000

생물학적 동등성 시험은 동일 성분을 동량 함유한 제제가 유사조건에서 투여되었을 경우 그 유효성분이 전신순환혈이나 작용부위에서 유용하게 되는 속도 및 양에 큰 차이가 없음을 입증하는 시험이다. 즉 이미 제조허가 되어 시판중인 의약품과 동일한 품목의 제조허가를 받기 위한 경우이거나 생체이용률이 동일함을 증명하기 위해 실시하는 시험이다. 우리 나라에서는 1989년 1월 1일 이후 허가된 전문의약품으로서 신약과 동일한 의약품, 패취제제, 제제개선을 통해 흡수율을 높이는 경우에 생물학적 동등성 시험을 하도록 의무화하고 있다. 미국 FDA는 1975년 6월 생체이용률, 생물학적 동등성에 관한 규제안을 발표하였고, 우리 나라에서도 1988년 10월에 생물학적 동등성 시험 기준을 제정하였다. 유럽에서는 1991년 12월 CPMP(Committee for Proprietary Medicinal Products)에 의해 최초로 "생체이용률 및 생물학적 동등성에 대한 가이드라인"이 채택되었다. 그후 전문가 회의를 거쳐 규정 전반에 관한 것과 일반적 항목에 대한 검토가 이루어져 최종 개정된 가이드라인이 만들어졌다. 현재 in vivo 생체 이용률을 비교하는 생물학적 동등성 시험의 중요성이 증대되고 있고, 국제적으로도 각 국가별 생물학적 동등성 시험의 평가방법이나 기준설정에 대한 연구가 다양하게 이루어지고 있다. 또한 ICH에서도 생물학적 동등성 시험의 국제적 조화를 위한 시도가 이루어지고 있다. 우리 나라의 현행 생물학적 동등성 기준은 1998년 개정된 것을 사용하고 있으나 국제적 발전 추세에 맞추어 기준의 제고를 모색하고 있다. 그 일환으로 유럽의 "의약품의 생체이용률 및 생물학적 동등성 시험 가이드라인"을 소개하고자 한다., globunlin II의 두 component로 분리(分離)되었고 oryzenin은 시료(試料) 육우(陸羽) 132호(號), 등판(藤坂) 5호(號), 관산(關山) 재건(再建)에서는 oryzenin I, oryzenin II, oryzenin III의 3 component를 분리(分離)하였고 팔달(八達), 진흥(振興), 서광(瑞光), 은방주(銀坊主), 다마금(多摩錦), Pin Galw56의 6시료(試料)에서는 oryzenin II, oryzenin III의 2 component만 분리(分離)하였다. 3. 각(各) fraction을 여지전기영동(濾紙電氣泳動)하여 각(各) component의 농도곡선(濃度曲線)에 의해 함량(含量)을 구(求)한 결과(結果) albumin 0.26%, globulin I, 0.35%, globulin II, 0.32%, prolamin, 0.41%, oryzenin I, 0.30%, oryzenin II, 2.23%, oryzenin III, 2.66%이었다.미국의 경우 3일 이내 전화나 FAX로 보고하고, 10일이내 문서로써 보고하도록 되어 있다. 이러한 임상적 안전성 자료 관리에 대한 신속 보고 정의 및 기준에 대해서는 ICH에서도 논의가 되어 Step 4까지 다다르고 있으므로 앞으로 각 국에서의 적용만 남아있는 상태이고 보면 신약의 개발과 더불어 임상시험에서의 부작용등의 안전성 자료 관리에 대한 중요성은 더욱 강조될 것이다.공하는 음식의 섭취정도에도 영향을 주고 있으므로 학생들에게 학부모와 전담교사 및 학교영양사는 학생들에게 이상적인 아침식사에 대한 교육은 물론이고 아침식사를 실천할 수 있도록 다양한 방안에 대해 함께 연구해야 하겠다. 정부차원에서 학교급식에 아침식사 프로그램을 도입할

• (The)Study of the Eastern Classic
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• no.50
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• pp.89-120
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• 2013

The concept of virtue seems to be one of the rare cases where the European and the Chinese traditions coincide. The meaning of the Latin word virtus and of Greek $aret{\acute{e}}$ seems to be similar to the Chinese $d{\acute{e}}$德. Most striking in virtue is that it is a capacity for self-realisation through action which is unique to man. On the other hand, there is something physical about it. It is the strength to do something. This strength overcomes the resistance of what is naturally given, it transforms the world, turns the natural world into a human one. In the Chinese tradition, $d{\acute{e}}$ 德, i.e. virtue, is therefore always connected with $da{\grave{o}}$ 道, the totality of natural forces. In the Chinese tradition, as opposed to the European one, virtue is itself considered to be a natural force that is present in man. This force sustains man's connectedness, unity and harmony with the surrounding world. Things exist through the unity of principle理 and ether氣. But the knowledge of this unity is due to principle. Moral and legal norms are shifted totally to the sphere of principle. Therefore their have found the final dissolution from a heroic models. Above all the classical Confucians, but also the other schools, would reply to this that there is nothing more precise than a concrete successful action. Its result fits the world perfectly. The difference is due to the differing interest of ethical thought. In the case of the Confucians the path is more direct. The actor establishes a precise pattern for other actions. Education therefore lies in detailed knowledge about forms of behaviour, not so much in conceptual differentiation. It is quite possible that generalisation may be a methodical prerequisite for success in this endeavour. That problem, too, is discussed. But the success of conceptualisation lies in the successful performance of individual actions, not in shaping actions in accordance with normative concepts.

• Journal of Navigation and Port Research
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• v.32 no.1
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• pp.109-114
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• 2008

This study is about the status and comparison of recreational scuba diving certification system in Southeast Asia countries. For the collection of the information, the contents of the numerous corresponding Internet sites were utilized, related documents were surveyed. And to supplement the information extensive interviews were held with the representatives of tourism department of many countries as well as staffs of diving associations, resort operators and diving instructors during various 2007 Dive Expos held in Southeast countries. In this paper, the relation between scuba certification and international standards were introduced for better understanding of the certification system. The research result shows that the scuba diving industry plays an important role in their country's tourism and the certification market of the Southeast Asia has grown to be greater than 30% of the world total market. However due to the facts that the scuba activity is originated from the western world and the controlling headquarters of the most certification agency are also located there, Southeast countries cannot take any leading roles in the scuba diving policies and systematic issues. Accordingly any modifications or improvements are expected to be very difficult. Also while Europeans and Americans have launched the programs and organizations for the quality assurance by cooperating with the international standards, but no such activity has yet appeared on the surface in Southeast Asia. According to the investigation the necessity will become bigger in near future.

• The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
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• v.17 no.1
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• pp.25-31
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• 2012

The frequency and abundance of jellyfish, presumably related with climate change, fisheries overexploitation, marine pollution including land reclamation and dyke construction, are increasing worldwide. This feature has attracted interest and concerns from general public and public officials, and government is seeking how the damages could be prevented or reduced down. Korean government, having recent huge blooms of jellyfish, engaged in reducing and/or countermeasuring jellyfish damages. Korean research themes include ecology and physiology of blooming jellyfish species, understanding of the blooming mechanism, and focus on the eradication of blooming jellyfish, without governmental integrative management plan. EU is undertaking scientific projects focused on understanding of the mechanism and control of jellyfish blooms, and establishment of an integrative management. In USA, government has established the code on jellyfish management for conserving and protecting the fish and shellfish resources and one of its department is specially assigned to monitor jellyfish appearance, undertake research, and prepare management plan. Japan also assigned a department and research institute for jellyfish research. Their main interest is to predict jellyfish drifting and mass bloom. Compared to Korea, USA, EU and Japan emphasize integrative management that includes ecological understanding, public education and outreaches, communication and control, if possible, of jellyfish blooms, based on scientific data. We suggest then, 1) establishment of an integrative scientific system consisting of policy and scientific experts to prepare inter-ministrial integrative management plan to effectively combat jellyfish blooms and to maximize the scientific result; 2) concept change from harmful to exploitable marine animal in policy making and research; and 3) active education and information service for people. We expect that these suggestions can be useful for jellyfish management and policy making on another harmful marine organisms.

• Archives of design research
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• no.16
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• pp.161-170
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• 1996

In an attempt to teace trands in fashion journalism based on the examination of recent fashion magazines in korea, this study has dealt with the followings: the number of articles on fashion, image of fashion, characteristics of articles, change in "coordinate" and titles, and length of time of publication. The results of this study follow: 1. Among the general magazines for ladies whose titles have been changed, those dedicated to the "Ms class" have increased the pages on fashion and coverage of casual brand: those for housewives have shown no change in contents despite the change in titles, 2. The length of time of publication does not affect the change in the number of articles on fashion. General magazines for ladies have shown the greater "coordinate" in articles on fashion. 3. In terms of the contents of articles on fashion, those devoted to fashion and clothing are specialized and innovation-oriented, whereas general magaines stress the provision of more practical information. 4. The emergence of the X-generation and the newer generation has resulted in positioning of clothing crand, making them chief tarhet readers.ing them chief tarhet readers.

• Journal of the Korean Recycled Construction Resources Institute
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• v.6 no.4
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• pp.324-330
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• 2018

In accordance with the amendment of the Industrial Safety and Health Act of 2007, Korea completely prohibited the import, distribution and manufacture of asbestos like Europe and Japan. Accordingly, the current problem of asbestos is the safe maintenance and disposal of asbestos construction material, the disposal of asbestos, and the final disposal of asbestos building materials. In the past, Korea used 100,000 tons of asbestos every year, and the building materials using it exceeded 1 million tons per year. These asbestos building materials continued to be used until 2006, and the Ministry predicted that these materials would continue to be maintained until 2044. When the permeable hardening agent is applied to the asbestos building material installed in the pre-pretreatment step for the harmless treatment of the asbestos waste and the dismantling is carried out, the scattering of the asbestos is suppressed in the disassembling step, detoxification treatment conditions can be improved. Therefore, permeable hardeners should be stably penetrated into asbestos building materials. In this study, it is suggested that pre - pretreatment methods for the harmlessization of waste asbestos building materials with medium density level can be presented. In order to efficiently perform pre - treatment for chemical harmlessness in the future, the mixing ratio of permeable hardener and middle water Optimization is the most important factor.

• Journal of the East Asian Society of Dietary Life
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• v.24 no.4
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• pp.514-528
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• 2014

This study examined the actual state and future improvement of food allergies in adolescents and adults in order to prevent damage. In this survey, proportions of females, people in their 40s, college graduates, and office workers and housewives with allergies were higher than other groups. Exactly 41.1% of participants responded that they had experienced food allergies while 58.9% responded that they had not. According to their responses, the most common food allergy symptom involved the skin while whole-body allergic reactions were rare. Most respondents answered that frequency of their food allergies was two or three times. There was a variety of allergenic foods, including fast food, eggs, mackerel and milk, and instant food was ranked as the most allergenic food. Therefore, in order to protect consumers from damage caused by food allergens, the food allergen labeling system must be improved. A better food allergen labeling system should be implemented to avoid potential risks of allergic reactions and ensure national food safety.