• Title/Summary/Keyword: 유도리나

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Isolation and Characterization of Antitumor Agents from Xanthium strumarium L. (한국산 도꼬마리로부터 항암물질의 분리 및 특성)

  • 김현수;이인선;여수환;성림식;유대식
    • KSBB Journal
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    • v.18 no.4
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    • pp.324-328
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    • 2003
  • In a mutagenicity test using the Salmonella typhimurium TA98 and TA100, the Xanthium strumarium L. extracts had not a mutagenicity. The extracts were assayed that antioxidative effect using a colony formation assay. The extracts showed protective effects against the cytotoxicity of H$_2$O$_2$ and increased the immunity induced by TNF and IL-1${\beta}$. The modulating effect of Xanthium strumarium L. extract on the induction of carcinogenesis by N-methyl-N'-nitro-N-nitrosoguanidin (MNNG), was investigated in Wistar rats. The GSH content was found to be reduced by MNNG treatment, but increased on adding extract. In addition the Xanthium strumarium L. extract increased p53 expression versus MNNG alone.

Experimental study of flow characteristics and sediment behaviors at the step down (단락부에서의 흐름 특성 및 역류에 의한 낙하리영역에서의 부류사 유동에 관한 연구)

  • 박기호
    • Water for future
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    • v.27 no.2
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    • pp.121-128
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    • 1994
  • Reduced trend of surface velocity, length of the separated drop area and width of potential core have been verified through experimental study of flow characteristics at the step down. To inverstigate sediment behaviors, experimental study which involved accumulated sediment transport reducing water velocity in the separated drop area was performed. From the experimental results, surface velocity, length of the separated drop area and width of potential core were formulated, and calculated output was corroborated by experimental outcome. Furthermore an examination of the parameter which is defined by $q_{sf}$/$q_{uo}$ was performed by detecting sediment in the separated drop area. Therefore these experiments can express the phenomena of flow characteristics and sediment behaviors at the step down.

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High quality $SiO_2$ gate Insulator with ${N_2}O$ plasma treatment and excimer laser annealing fabricated at $150^{\circ}C$ (${N_2}O$ 플라즈마 전처리와 엑시머 레이저 어닐링을 통한 $150^{\circ}C$ 공정의 실리콘 산화막 게이트 절연막의 막질 개선 효과)

  • Kim, Sun-Jae;Han, Sang-Myeon;Park, Joong-Hyun;Han, Min-Koo
    • Proceedings of the KIEE Conference
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    • 2006.10a
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    • pp.71-72
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    • 2006
  • 플라스틱 기판 위에 유도 결합 플라즈마 화학적 기상 증착장치 (Inductively Coupled Plasma Chemicai Vapor Deposition, ICP-CVD) 를 사용하여 실리콘 산화막 ($SiO_2$)을 증착하고, 엑시머레이저 어널링 (Excimer Laser Annealing, ELA) 과 $N_{2}O$ 플라즈마 전처리를 통해, 전기용량-전압(Capacitance-Voltage, C-V) 특성과 항복 전압장 (Breakdown Voltage Field) 과 같은 전기적 특성을 개선시켰다. 에너지 밀도 $250\;mJ/cm^2$ 의 엑시머 레이저 어닐링은 실리콘 산화막의 평탄 전압 (Flat Band Voltage) 을 0V에 가까이 이동시키고, 유효 산화 전하밀도 (Effective Oxide Charge Density)를 크게 감소시킨다. $N_{2}O$ 플라즈마 전처리를 통해 항복 전압장은 6MV/cm 에서 9 MV/cm 으로 향상된다. 엑시머 레이저 어닐링과 $N_{2}O$ 플라즈마 전처리를 통해 평탄 전압은 -9V 에서 -1.8V 로 향상되고, 유효 전하 밀도 (Effective Charge Density) 는 $400^{\circ}C$에서 TEOS 실리콘 산화막을 증착하는 경우의 유효 전하 밀도 수준까지 감소한다.

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Material Characteristics of White Wares from Yeongdong Province, Gangwon-do: Gangneung and Donghae Kiln Sites (강원 영동지역 백자의 재료과학적 특성 연구: 강릉 남양리 백자가마터와 동해 발한동2(사문동) 가마터를 중심으로)

  • Lee, Byeong Hoon;So, Myoung-Gi
    • Journal of Conservation Science
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    • v.31 no.3
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    • pp.181-192
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    • 2015
  • This study aims to examine production technique of twelve white wares from the Gangneung Namyang-ri and Donghae Balhan-dong2(Samun-dong) kiln sites, Kangwon Province and characteristics of the used materials, and to find a correlation among materials of the excavated white wares. X-ray fluorescence sequential spectroscopy(XRF), X-ray diffraction(XRD), Dilatometer and Inductively coupled plasma mass spectrometry(ICP-MS), Inductively coupled plasma automic emission spectrometer(ICP-AES) were applied to determine the chemical composition, crystalline phase of samples, firing temperatures, trace elements and rare earth elements. When analyzing body crystalline phases of the white wares using the XRD method, quartz and mullite were extracted from all the samples. Though firing temperature of each sample was different, they were mostly fired at a temperature below $1200^{\circ}C$. Analyzing the excavated white wares using the Seger formula, compositional properties of white wares in Gangneung Namyang-ri kiln showed diffrently from the Donghae Balhan-dong2(Samun-dong) kiln. The body of white wares from Gangneung Namyang-ri kiln have higher raito of $RO_2$ and $RO+R_2O$ than of white wares from Donghae Balhan-dong2(Samun-dong) kiln site. The white wares from Gangneung Namyang-ri kiln and Donghae Balhan-dong2(Samun-dong) kiln were made of host rocks of the different geological origin, according to the result of rare earth elements analysis.

Effect of Physical Pre-treatment of Mature Seed in Callus Formation and Plant Regeneration of Zoysiagrass (잔디종자의 물리적 전처리가 캘러스 형성과 식물체 재분화에 미치는 효과)

  • Ahn, Na-Young;Kim, Yong-Goo;Rahman, Md. Atikur;Bae, Eun Ji;Choi, Su Min;Lee, Kwang Soo;Lee, Byung-Hyun
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.35 no.4
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    • pp.316-320
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    • 2015
  • In order to improve the transformation efficiency of zoysiagrass by increasing the frequency of callus formation from mature seeds and plant regeneration, the effect of pre-treatment with sea sand was examined. Mature zoysiagrass seeds were given 10 min of swelling time before sea sand treatment using a sea sand and seed ratio of 1 : 1 and a vortex shaking speed of 6 (1,000 rpm) for 10 min. The seeds showed increased callus formation that was more than 2 times the rate in the control. In addition, plant regeneration efficiency was also increased when embryogenic callus induced from sea sand-treated mature seeds was cultured in regeneration medium. These results will be very helpful for improving the genetic transformation frequency of zoysiagrass, a recalcitrant monocot grass.

Treatment of Industrial Wastes by Melting Using H.F. Induction Furnace (고주파 유도로를 이용한 산업 폐기물의 용융처리)

  • 정진기;정헌생;이재천;윤인주;남기대
    • Resources Recycling
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    • v.6 no.1
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    • pp.23-28
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    • 1997
  • Iron and slag were prepared by melting mixed industrial wastes in an induction furnace. The wastes were steel can, limestone sludge, waste foundry sand, coal fly ash, and glasses. The effects of their mixing ratio on the charactenstics of the meltcd slag were investigated. The wastes were melted to slag under the constant basicity of 1.2. It was found that the major phases of the slag were P-C,S and C,AS and then ratio was determined by the mixing ratio af waste materials. The recovery of iron was about 93-95%. The feasibility of using the slag as the aggregate was confirmed by thc elution and campression tests.

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Large-scale Spatial Reasoning using MapReduce Framework (맵리듀스 프레임워크를 이용한 대용량 공간 추론 방식)

  • Nam, Sang-Ha;Kim, In-Cheol
    • Proceedings of the Korea Information Processing Society Conference
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    • 2014.04a
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    • pp.769-772
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    • 2014
  • Jeopardy 퀴즈쇼와 같은 DeepQA 환경에서 인간을 대신해 컴퓨터가 효과적으로 답하기 위해서는 인물, 지리, 사건, 역사 등을 포함하는 광범위한 지식베이스와 이를 토대로 한 빠른 시공간 추론 능력이 필요하다. 본 논문에서는 대표적인 병렬 분산 컴퓨팅 환경인 하둡/맵리듀스 프레임워크를 이용하여 방향 및 위상 관계를 추론하는 효율적인 대용량의 공간 추론 알고리즘을 제시한다. 본 알고리즘에서는 하둡/맵리듀스 프레임워크의 특성을 고려하여 병렬 분산처리의 효과를 높이기 위해, 지식 분할 문제를 맵 단계에서 해결하고, 이것을 토대로 리듀스 단계에서 효과적으로 새로운 공간 지식을 유도하도록 설계하였다. 또한, 본 알고리즘은 초기 공간 지식베이스로부터 새로운 지식을 유도할 수 있는 기능뿐만 아니라 초기 공간 지식베이스의 불일치성도 미연에 감지함으로써 불필요한 지식 유도 작업을 계속하지 않도록 설계하였다. 본 연구에서는 하둡/맵리듀스 프레임워크로 구현한 대용량 공간 추론기와 샘플공간 지식베이스를 이용하여 성능 분석 실험을 수행하였고, 이를 통해 본 논문에서 제시한 공간 추론 알고리즘과 공간 추론기의 높은 성능을 확인 할 수 있었다.

Induced Autophagy Regulates Salmonella enterica serovar Typhimurium Infection in Murine Macrophage (쥐의 큰포식세포주에서 자가포식현상에 의한 Salmonella enterica serovar Typhimurium의 감염 조절)

  • Lee, Sunhye;Kim, Ju-Young;Lee, Hyo-Ji;Jung, Yu-Jin
    • Korean Journal of Microbiology
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    • v.50 no.1
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    • pp.27-32
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    • 2014
  • Autophagy is one of the lysosomal degradation pathways to maintain cellular homeostasis. The damaged proteins or organelles are uptaken through extra- and intra-cellular stress, starvation and infected pathogens, subsequently, autophagosomes are fused with lysosomes to break down the molecules. Salmonella enterica serovar Typhimurium (S. Typhimurium), intracellular bacteria, cause acute gastroenteritis and food poisoning. Given that autophagy induced by S. Typhimurium plays an important role in the cells to control the infection, we identify whether the induction of autophagy with rapamycin, chemical inducer of autophagy, before infection regulates S. Typhimurium infection. After treatment of rapamycin or 3-methyladenine (3-MA), autophagy inhibitor, RAW264.7 cells were infected with S. Typhimurium. Pretretment of rapamycin decreased the growth rate of S. Typhimurium in the cells; otherwise, pretreatment of 3-MA increased the growth rate of S. Typhimurium. The expression of autophagy-related genes was significantly increased in the S. Typhimurium-infected cells pretreated with rapamycin. To examine whether induced autophagy by rapamycin control the infection with increase the production of reactive oxygen species (ROS) and nitric oxide (NO), antibacterial radical substrates were measured in infected cells followed by the treatment with either rapamycin or 3-MA. NO production increased in RAW264.7 cells; otherwise, ROS production remained unchanged during the infection. These findings suggest that inducing autophagy with rapamycin reveals antimicrobial activity as producing NO against S. Typhimurium infection in mouse macrophages.

Guidance Laws for Aircraft Automatic Landing (항공기 자동착륙 유도 법칙에 관한 연구)

  • Min, Byoung-Mun;No, Tae-Soo;Song, Ki-Jung
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.30 no.5
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    • pp.41-47
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    • 2002
  • In this paper, a guidance law applicable to aircraft automatic landing is proposed and its performance is compared with the conventional ILS-type landing approach. The concept of miss distance, which is commonly used in the missile guidance laws, and Lyapunov stability are effectively combined to obtain the landing guidance law. The new landing guidance law is integrated into the existing controller and is applied to the landing approach and flare phases of landing procedure. Numerical simulation results show that the new landing guidance law is a viable alternative to the conventional strategies that directly control the longitudinal deviation or altitude.

Finite Element Analysis for Vibration of Laminated Plate Using a Consistent Discrete Theory Part I : Variational Principles (복합재료적층판의 진동해석을 위한 유한요소모델 I. 변분원리의 유도)

  • 홍순조
    • Computational Structural Engineering
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    • v.7 no.4
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    • pp.85-101
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    • 1994
  • A family of variational principles governing the dynamics of laminated plate has been derived using a variationally consistent shear deformable discrete laminated plate theory with particular reference to finite element procedures. The theoretical basis for the derivation is Sandhu's generalized procedure for the variational formulation of linear coupled boundary value problem. As the bilinear mapping to write the operator matrix of the field equations in self-adjoint form, convolution product was employed. Boundary conditions, initial conditions and probable internal discontinuity were explicitly included in the governing functionals. Some interesting extensions and specializations of the general variational principle were presented, which can provide many different finite element formulations for the problem.

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