• Title/Summary/Keyword: 위험표현

Search Result 355, Processing Time 0.03 seconds

유산균 발효에서 항생물질 불활화에 관한 연구

  • 강국희;이수원;김영진;김영창
    • Proceedings of the Korean Society for Applied Microbiology Conference
    • /
    • 1978.10a
    • /
    • pp.204.2-205
    • /
    • 1978
  • 발효유 원료유중에 항생물질이 함유되어있을 경우 이것이 발효유 제조에 미치는 영향을 검토하였다. 발효유의 원가유 살균과정, 배양기간, 보존기간중에 있어서 항생물질의 변화를 검토하기 위하여 Bacillus stearothermophilus var. calidolactis C 953을 사용한 cylinder plate법으로 penicillin의 역가를 측정하였다. 저온 장시간 $살균(60^{\circ}C,$ 30분) 조건에서는 조금도 불활성화되지 않았으나, 온도를 높이고, 시간을 길게함에 따라 점점 불활화률이 높아져 $고압멸균조건(121^{\circ}C,$ 15분)에서는 약 90% 이상이 불활화되었다. 또 현재 우리나라에서 발효유제조에 사용되고 있는 Lactobacillus casei, Hy3와 Lactoba-cillus bulgaricus Hy4A, Hy4B를 사용하여 $37^{\circ}C에서$ 배양할 경우 배양기간 중에 있어서 penicillin은 2일내에 95% 이상 불활화되었다. 그리고 $보존기간(5^{\circ}C)$ 중에는 phosphate buffer(pH 6.0)와 10% skim milk의 경우에 10일까지도 거의 불활화가 되지 않았으나, 발효유내에서는 5일만에 85% 이상이 불활화된다는 결과를 얻었다. 이와같은 발효유 배양기간과 보존기간 중의 penicillin 불활화의 원인을 규명하기 위하여 각종 유기산의 영향을 조사한 결과(조건 pH.3.30~3.45, 보존온도 $37^{\circ}C),$ 염산과 유산의 경우 24시간, 구연산의 경우 48시간, 초산의 경우 72시간내에 실험에 사용한 penicillin 농도의 99.99%가 불활화되었다. 이러한 결과로 볼 때 유산발효에서 penicillin이 불활화되는 주원인은 발효에 의하여 생성된 유기산에 의한 것으로 추정된다.방식이군이 중지방식이군과 고지방식이군에 비해 혈장내 LCAT 활성이 유의하게9p<0.001) 증가하였다. 3) 간의 콜레스테롤합성 능력은 정어리유군이 다른지방군보다(p<0.001), 무지방식이군이 식이지방첨가군보다(p<0.001), 동물성지방군의 식물성유지군보다 유의하게(p<0.001) 증가하였으나, 식이 지방의 수준에 의한 차이는 나타나지 않았다. 수용성 식이섬유소가 생리져 기능이 거의 비슷하고 무독성이 관찰됨으로써 신갈나무로부터 제조된 수용성 식이섬유소의 제조 방법이 우수하다고 볼 수 있다.있었다.세에 해당되는 중년 여성의 에너지, 단백질, 철분 섭취량을 권장량과 비교하여 보면, 각각 74.8$\pm$12.6%, 94.6$\pm$26.4% 및 64.5$\pm$14.1%로 당뇨군 (각각 112.8$\pm$28.5%, 157.8$\pm$68.2%, 92.8$\pm$21.7%)에 비해 유의하게 낮았고 정상군과는 유의한 차이를 보이지 않았다.상고나성이 있었다. 혈중 호모시스테인 농도는 질병의 위험요인으로서 뿐 아니라 대사적으로 밀접하게 연관된 비타민 영양상태의 biomarker로서도 그 영향력이 크다고 할 수 있다. 따라서 성별에 다른 다양한 연령집단에서 건강한 일반인과 심혈관계 질환자 등을 대상으로 호모시스테인과 비타민 영양상태에 대한 연구가 체계적으로 이루어 져야 할 것이다.태를 보다 효율적으로 증진시킬 수 있는 대안이 마련되어져야 한다고 사료된다.$\ulcorner$순응$\lrcorner$의 범위를 벗어나지 않는다. 그렇기 때문에도 $\ulcorner$순응$\lrcorner$$\ulcorner$표현$\lrcorner$의 성격과 형태를 외형상으로 더욱이 공간상에서는

  • PDF

A Comparative Study on the Infinite NHPP Software Reliability Model Following Chi-Square Distribution with Lifetime Distribution Dependent on Degrees of Freedom (수명분포가 자유도에 의존한 카이제곱분포를 따르는 무한고장 NHPP 소프트웨어 신뢰성 모형에 관한 비교연구)

  • Kim, Hee-Cheul;Kim, Jae-Wook
    • The Journal of Korea Institute of Information, Electronics, and Communication Technology
    • /
    • v.10 no.5
    • /
    • pp.372-379
    • /
    • 2017
  • Software reliability factor during the software development process is elementary. Case of the infinite failure NHPP for identifying software failure, the occurrence rates per fault (hazard function) have the characteristic point that is constant, increases and decreases. In this paper, we propose a reliability model using the chi - square distribution which depends on the degree of freedom that represents the application efficiency of software reliability. Algorithm to estimate the parameters used to the maximum likelihood estimator and bisection method, a model selection based on the mean square error (MSE) and coefficient of determination($R^2$), for the sake of the efficient model, were employed. For the reliability model using the proposed degree of freedom of the chi - square distribution, the failure analysis using the actual failure interval data was applied. Fault data analysis is compared with the intensity function using the degree of freedom of the chi - square distribution. For the insurance about the reliability of a data, the Laplace trend test was employed. In this study, the chi-square distribution model depends on the degree of freedom, is also efficient about reliability because have the coefficient of determination is 90% or more, in the ground of the basic model, can used as a applied model. From this paper, the software development designer must be applied life distribution by the applied basic knowledge of the software to confirm failure modes which may be applied.

Effect of Delayed Intensification on Survival of Childhood Acute Lymphoblastic Leukemia (소아기 급성 림프구성 백혈병에서 후기강화요법의 효과)

  • Lee, Jie Yeon;Youn, Sue;Kwon, Byoung Chul;Lyu, Chuhl Joo;Kim, Hwang Min
    • Clinical and Experimental Pediatrics
    • /
    • v.46 no.12
    • /
    • pp.1260-1265
    • /
    • 2003
  • Purpose : In 1970, the Berlin-Frankfurt-Munster(BFM) group introduced an intensification therapy after remission induction to reduce relapse of acute lymphoblastic leukemia(ALL) in childhood. Delayed intensification(DI) phase has been included for treatment of ALL in our hospital since the mid-1990s. The purpose of this study is to evaluate the outcome with vs. without DI phase and the outcome with two vs. one DI phase for intermediate risk patients. Methods : One hundred and thirty nine children with ALL who were treated at the Department of Pediatrics of Wonju Christian Hospital and Yonsei University Medical Center between March, 1990 and July, 2002 were analysed retrospectively. Results : Thirty-eight patients were treated with a DI phase, and 101 patients were treated without a DI phase. Among the DI patients, seven patients were treated with a double DI phase. Five-year overall survival(OS) in the low, intermediate, and high risk groups were 68%, 66% and 58%, respectively. 5-year OS in DDI, DI, and control were 95%, 86% and 40%, respectively. In the low risk group, 5-year event free survival(EFS) in DI, and control were 94% and 58%, respectively. Conclusion : Delayed intensification improved EFS on childhood ALL in all risk groups.

Stability Evaluation of Track on Conventional Line According to Traveling Tilting Train (틸팅차량 주행에 따른 기존선 궤도의 주행안정성 평가)

  • Park, Yong-Gul;Eum, Ki-Young;Choi, Jung-Youl;Sung, Deok-Yong
    • Journal of the Korean Society for Railway
    • /
    • v.10 no.6
    • /
    • pp.701-708
    • /
    • 2007
  • A tilting train, which was developed to run the curve section without reducing the speed and compromising the riding quality, can improve the speed so as to reduce the travel time, compared to the existing trains. Then the force generated by the train operation to the track is in proportion to train operation speed, which means the track shall bear the increased force as much as the increase in train operation speed. Particularly, wheel load and lateral wheel load generated by train operation and distributed to the rail tend to cause the track to suffer the strain and furthermore the severe disaster such as derailment. To deal with such problem and ensure the train will run safety and stably, the tolerance in wheel load change, lateral wheel load and derailment coefficient was determined for quantitative evaluation of the train operation stability. In this study, derailment coefficient of inner and outer rail at existing curve section of tilting train was determined to evaluate the curve radius, possibility of acceleration and the need of rail improvement, which was then compared with the existing traditional train and high speed train. Conducting the quantitative evaluation of dynamic wheel load and lateral wheel load of each train, which was based on field survey, derailment coefficient and static & dynamic wheel load change, which serve the evaluation criteria of train operation stability, were determined for comparison with the standards, thereby analyzing the stability of the tilting train.

Importance of Dynamic Cue in Silhouette-Based Gait Recognition (실루엣 기반 걸음걸이 인식 방법에서 동적 단서의 중요성)

  • Park Hanhoon;Park Jong-Il
    • Journal of the Institute of Electronics Engineers of Korea SP
    • /
    • v.42 no.3 s.303
    • /
    • pp.23-30
    • /
    • 2005
  • As a human identification technique, gait recognition has recently gained significant attention. Silhouette-based gait recognition is one of the most popular methods. This paper aims to investigate features that determine the style of walking in silhouette-based gait recognition. Gait can be represented using two cues: static(shape) cue and dynamic(motion) cue. Most recently, research results have been reported in the literature that the characteristics of gait are mainly determined by static cue but not affected by dynamic cue. Unlike this, experimental results in this paper verifies that dynamic cue is as important as and in many cases more important than static cue. For experiments, we use two well-blown gait databases: UBC DB and Southampton Small DB. The images of UBC DB correspond to the 'ordinary' style of walking. The images of Southampton Small DB correspond to the 'disguised' (not ordinary by wearing special clothes or bags) style of walking. As results of experiments, the recognition rate was 100% by static cue and $95.2\%$ by dynamic cue for the images of UBC DB. For the images of Southampton Small DB, the recognition rate was $50.0\%$ by static cue and $55.8\%$ by dynamic cue. The risk against correct recognition was 0.91 by static cue and 0.97 by dynamic cue for the images of UBC DB. For the images of Southampton Small DB, the risk was 0.98 by static cue and 0.98 by dynamic cue. Consequently, the characteristics of ordinary gait are mainly determined by static cue but that of disguised gait by dynamic cue.

Re-contextualizing Urban Cultural Studies in Crisis -Linking with Fiske's Later Criticism of the City (위기의 도시 문화연구 재문맥화 -후기 피스크 비판적 공간 사유와의 접선)

  • Jeon, Gyuchan
    • Korean journal of communication and information
    • /
    • v.70
    • /
    • pp.35-65
    • /
    • 2015
  • This paper is consisted of the thesis that the decontextualized limitation of media cultural studeis in Korea should be overcome by walking into and linking with today's urban crisis and everyday life. It proposes us to become the flaneurs who do not hesitate to go to, think of, and experience actively the city in crisis under the capital/state domination. It's conclusion would be that we must practice participation observation at the fields and thus recover the critical element of cultural studies writing, by entering into the city and seeing at the features of crisis routinely expressed and symptomatically appear in there. For and before this, the author will first of all pay attention to John Fiske in later period, who was merely perceived and falsely regarded as an active audience theorist. He will also review de Certeau from whom Fiske has borrowed the concept of tactics, and Berman who has further practiced the very spatial tactic. The paper is prepared so as to expand the ideas and thoughts of them who have gone beyond the boundary of text, audience and onto the context of urban space. It's goal is much more than rescuing, recovering Fiske's alternative trajectory. It tries to reconstruct the tradition of urban media cultural studies critically connected with the dangerous, life-threatening capitalist condition. Furthermore, by filling up the theoretical vacuum left behind disconnected and cut away from Fiske, it attempts to find a vision, prospect of cultural studies that will actively engage themselves dialectally with dangerous yet hopeful life of the city and its popular masses.

  • PDF

Application of Spatial Data Integration Based on the Likelihood Ratio Function nad Bayesian Rule for Landslide Hazard Mapping (우도비 함수와 베이지안 결합을 이용한 공간통합의 산사태 취약성 분석에의 적용)

  • Chi, Kwang-Hoon;Chung, Chang-Jo F.;Kwon, Byung-Doo;Park, No-Wook
    • Journal of the Korean earth science society
    • /
    • v.24 no.5
    • /
    • pp.428-439
    • /
    • 2003
  • Landslides, as a geological hazard, have caused extensive damage to property and sometimes result in loss of life. Thus, it is necessary to assess vulnerable areas for future possible landslides in order to mitigate the damage they cause. For this purpose, spatial data integration has been developed and applied to landslide hazard mapping. Among various models, this paper investigates and discusses the effectiveness of the Bayesian spatial data integration approach to landslide hazard mapping. In this study, several data sets related to landslide occurrences in Jangheung, Korea were constructed using GIS and then digitally represented using the likelihood ratio function. By computing the likelihood ratio, we obtained quantitative relationships between input data and landslide occurrences. The likelihood ratio functions were combined using the Bayesian combination rule. In order for predicted results to provide meaningful interpretations with respect to future landslides, we carried out validation based on the spatial partitioning of the landslide distribution. As a result, the Bayesian approach based on a likelihood ratio function can effectively integrate various spatial data for landslide hazard mapping, and it is expected that some suggestions in this study will be helpful to further applications including integration and interpretation stages in order to obtain a decision-support layer.

Virtual Satellite and Virtual Range Measurement Generation for the GNSS Position Accuracy Improvement (사용자 위치해 정확도 향상을 위한 가상위성 및 가상거리측정값 생성)

  • Song, Choongwon;Ahn, Jongsun;Choi, Moonseok;Jang, JinHyeok;Heo, MoonBeom;Lee, Young Jae
    • Journal of the Korean Society for Aeronautical & Space Sciences
    • /
    • v.45 no.9
    • /
    • pp.757-765
    • /
    • 2017
  • GNSS (Global Navigation Satellite System) Position Accuracy depends on pseudo-range measurement and DOP (Dilution Of Precision) which indicates about navigation satellite geometry. Pseudo-Range has many error sources such as satellite clock, orbit, ionosphere, troposphere, multipath and so on. For the improvement of the accuracy, user can use corrected pseudo-range in DGPS (Differential Global Positioning System), which is one of the relative positioning methods. But, stationary station is needed in relative positioning. In case of DOP, Signal reception environment is important. If receiver sets in the center of city, it could be interrupted reception by buildings. This environment leads to decrease the number of visible satellites and to increase DOP. This paper proposes the concept of GNSS positioning with virtual satellites which have usable VRM (Virtual Range Measurement). Via virtual satellites and VRM, users could get an accurate position. Especially referred virtual satellites constellation has an effect on vertical error.

Sparganum infections in normal adult population and epileptic patients in Korea: A seroepidemiologic observation (항체검사에 의한 한국인 스파르가눔 감염의 혈청역학적 조사)

  • Yoon Kong;Seung-Yull Cho;Woo Shik Kang
    • Parasites, Hosts and Diseases
    • /
    • v.32 no.2
    • /
    • pp.85-92
    • /
    • 1994
  • A seroepidemiologic observation of anti-Spirometrc erinacei plerocercoid (sparganum) antibody (IgG) in serum was made in normal adult and epileptic patients in Korea from february, 1987 to September, 1990. Sera were tested by enzyme-linked immunosorbent assay (ELISA) for anti-sparganum antibody together with anti-Taenic soEiun metacestode, and anti-Parusonimus westermcni antibodies. Sera reacted positively to sparganum antigen only were considered. Positive rate for anti-sparganum antibody in 850 normal adults was 1.9% (standardized rate by provincial population was 1.7%). In 2,667 randomly selected patients of epilepsy at 28 local centers of the Changmi Club, positive rate was 2.5% (standardized rate: 2.3%). In both normal adult and patient groups, the higher antibody rates were observed in Kangwon and Chonnam Provinces. Positive rates were 10 times higher in male than in female in normal adults and 4.5 times in male epileptic patients. The rates were elevated especially with age over 30-year. odd ratio of the antibody was 1.32 which indicated an ambiguous etiologic factor for epilepsy.

  • PDF

A study on the relationship between initial and final convergence in NATM tunnels (NATM 터널 굴착시 초기 내공변위와 최종 내공변위의 상관관계 연구)

  • Kim, Bum-Joo;Hwang, Young-Cheol
    • Journal of Korean Tunnelling and Underground Space Association
    • /
    • v.10 no.3
    • /
    • pp.233-243
    • /
    • 2008
  • A tunnel behavior predicted in the investigation and design stage is often different from its actual behavior due to mainly the complexity of ground conditions. In a tunnel construction, therefore, it is necessary to ensure the stability of the tunnel by predicting the behaviors of the ground and the supports through observations and measurements, and modifying immediately excavation and reinforcing methods when necessary. To do so, it is important to be able to predict the final tunnel behavior based on the initial tunnel behavior as early as possible. In this study, the correlations were obtained between the initial and the final convergence by analyzing statistically the convergence measurement data, collected from two domestic road tunnels under construction using NATM. In order to estimate the unknown displacements, occurred during the period between the excavation and the first measurement, two methods were used - one is the method by means of regression analysis using a modified exponential function and the other the method by a simple linear regression analysis using the data measured within the distance from tunnel face equal to the tunnel diameter (D). Finally, the relationships were obtained between the initial and final convergence, including the non-measured displacements estimated from the two different methods, by performing linear regression analyses. The regression analysis results showed that there are clear linear relationships between the initial and final convegence and the difference between the two linear regression equations was not that large for when using the exponential function and the simple linear function to estimate the non-measured displacements.

  • PDF