• Title/Summary/Keyword: 위험성평가시스템

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In Silico Approach for Predicting Neurotoxicity (In silico 기법을 이용한 신경독성 예측)

  • Lee, So-yeon;Yoo, Sun-yong
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2022.05a
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    • pp.270-272
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    • 2022
  • Safety is one of the factors that prevent clinical drugs from being distributed on the market. In the case of neurotoxicity, which is the main cause of safety problems caused by drug side effects, risk assessment of drugs and compounds is required in advance. Currently, experiments for testing drug safety are based on animal experimetns, which have the disadvantage of being time-consuming and expensive. Therefore in order to solve the above problem, a neurotoxic prediction model through an in silico experiment was suggested. In this study, the category of neurotoxicity was expanded using a unified medical language system and various related compound data were obtained based on an integrated database. The SMILES (Simplified Molecular Input Line Entry System) of the obtained compounds were converted into fingerprints and it is used as input of machine learning. The model finally predicts the presence or absence of neurotoxicity. The experiment proposed in this study can reduce the time and cost required for the in vivo experiment. Furthermore, it is expected to shorten the research period for new drug development and reduce the burden of suspension of development.

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R Wave Detection Algorithm Based Adaptive Variable Threshold and Window for PVC Classification (PVC 분류를 위한 적응형 문턱치와 윈도우 기반의 R파 검출 알고리즘)

  • Cho, Ik-Sung;Kwon, Hyeog-Soong
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.34 no.11B
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    • pp.1289-1295
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    • 2009
  • Premature ventricular contractions are the most common of all arrhythmias and may cause more serious situation like ventricular fibrillation and ventricular tachycardia in some patients. Therefore, the detection of this arrhythmia becomes crucial in the early diagnosis and prevention of possible life threatening cardiac diseases. Particularly, in the healthcare system that must continuously monitor people's situation, it is necessary to process ECG signal in realtime. In other words, design of algorithm that exactly detects R wave using minimal computation and classifies PVC is needed. So, R wave detection algorithm based adaptive threshold and window for the classification of PVC is presented in this paper. For this purpose, ECG signals are first processed by the usual preprocessing method and R wave was detected and adaptive window through R-R interval is used for efficiency of the detection. The performance of R wave detection and PVC classification is evaluated by using MIT-BIH arrhythmia database. The achieved scores indicate 99.33%, 88.86% accuracy respectively for R wave detection and PVC classification.

A Study on Damage Effects Assessment for Asphyxiation Accident due to Malfunction of Gas Type Fire Extinguishing System (가스계 소화설비 오작동으로 인한 질식사고의 피해영향 평가)

  • Kim, Eui-Soo
    • Journal of the Korean Institute of Gas
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    • v.24 no.2
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    • pp.36-43
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    • 2020
  • Gas system fire extinguishing equipment is a very economically useful facility, but if it is not used for a long period of time after installing the equipment, there is possibility of rupture due to corrosion of containers and operation errors of equipment systems, and this is very dangerous. However, it is impossible to experiment to check whether the equipment is operating normally. If gas is temporarily released into the enclosed space due to rupture and malfunction, it can cause serious human damage due to gas suffocation. In this study, based on the suffocation death accident of gas system fire extinguishing facility, the inflow path of released gas and the possibility of death and time to death were estimated using a 3D scan and FLACS.

Technical Status of Environmental Radiation Monitoring using a UAV and Its Field Application to the Aerial Survey (무인기를 이용한 광역부지 환경방사선측정 기술 현황 및 현장 적용 연구)

  • Ji, Young-Yong;Min, Byung Il;Suh, Kyung-Suk;Joung, Sungyeop;Kim, Kyoung-Pyo;Park, Jin-Ho
    • Journal of Korea Society of Industrial Information Systems
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    • v.25 no.5
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    • pp.31-39
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    • 2020
  • According to lessons learned from an accident of Fukushima Daiichi nuclear power plant, it is advisable to make a comprehensive radiation survey by the accident phase for efficient response and risk management using diverse survey platforms. This study focuses on the technical status of environmental radiation monitoring using a UAV (Unmanned aerial vehicle) and the performance test of developed aerial survey system based on two detectors with an high energy resolution through the field application to contaminated areas. Finally, the performance of aerial survey at diverse flight heights was successfully achieved by introducing the correction factor to represent the results into ambient dose rate at 1m above the ground.

A Smart River Management Plan for Eco-Delta City (에코델타시티 스마트 하천관리 방안)

  • Yeo, Hong Koo;Kang, Jungu;Shim, Kyu Cheoul;Hong, Il
    • Proceedings of the Korea Water Resources Association Conference
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    • 2022.05a
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    • pp.3-3
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    • 2022
  • 부산 에코델타시티는 세종 5-1 생활권과 더불어 스마트시티 국가시범도시이며, 사업대상지역은 평강천이 관류하여 맥도강, 서낙동강 본류로 흐르는 세물머리지역이 그 중심에 위치하고 있다. 하천을 중심으로 스마트시티가 조성되고 있으나 하천관리는 유역내 홍수관리, 수질관리 등등에 관한 정부주체 상위계획에 종속성이 강한 공공분야로서 단위사업에서 스마트시티에 걸맞는 하천관리계획을 수립하고 시행하는 것은 많은 어려움이 존재한다. 하천관리의 주 관심 대상은 이수를 제외하면 치수, 하천환경, 친수, 하천시설물로 대별할 수 있으며, 스마트 하천관리란 이들에 대한 현황 정보구축 및 지속적인 현행화, 그리고 이들 실제 정보를 토대로 한 합리적 운영과 실시간 연계운영 실현으로 공공서비스를 제공하는 것이라 할 수 있을 것이다. 본 연구는 국가연구개발사업에서 연구한 각 분야별 하천관리기법을 에코델타시티에 시범적용하여 스마트하천관리를 구현할 수 있는 방법을 제시하고자 하였다. 에코델타시티 조성사업의 진행수준으로 인해 취득하기 어려운 정보들은 수립된 계획을 참조하여 적용하였다. 유역내 주 대상 하천들은 델타지역에서 수문으로 통제되므로 일반적인 하천과 달리 정수역에 가까운 특이한 수리특성을 보이고 있지만, 우선 스마트 하천관리를 위한 일반적인 과정들을 시범적용 해보고 필요에 따라 특성 고려 방안을 찾고자 하였다. 유역내 정량적 홍수위험도 평가, 하천환경 평가 적용방안, 하천시설물 관리방안, 주요 지점의 실시간 모니터링 방안 등이 에코델타시티 조성사업 진행단계를 고려하여 수행되고 있다. 사용편의성과 지속가능성을 담보하기 위한 하천연계플랫폼을 구축하여, 개발된 기법들을 각각 내부 모듈로 장착하거나 완성도에 따라 외부모듈로 연계할 수 있도록 하였다. 현재 개발된 기법들의 시스템화 완성 및 관련 정보들의 데이터베이스 확대를 위한 노력이 진행되고 있으며, 향후 하천관리연계플랫폼의 실제 운영을 통하여 완성도를 높여갈 계획이다.

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Development Process and Methods of Audit and Certification Toolkit for Trustworthy Digital Records Management Agency (신뢰성 있는 전자기록관리기관 감사인증도구 개발에 관한 연구)

  • Rieh, Hae-young;Kim, Ik-han;Yim, Jin-Hee;Shim, Sungbo;Jo, YoonSun;Kim, Hyojin;Woo, Hyunmin
    • The Korean Journal of Archival Studies
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    • no.25
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    • pp.3-46
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    • 2010
  • Digital records management is one whole system in which many social and technical elements are interacting. To maintain the trustworthiness, the repository needs periodical audit and certification. Thus, individual electronic records management agency needs toolkit that can be used to self-evaluate their trustworthiness continuously, and self-assess their atmosphere and system to recognize deficiencies. The purpose of this study is development of self-certification toolkit for repositories, which synthesized and analysed such four international standard and best practices as OAIS Reference Model(ISO 14721), TRAC, DRAMBORA, and the assessment report conducted and published by TNA/UKDA, as well as MoRe2 and current national laws and standards. As this paper describes and demonstrate the development process and the framework of this self-certification toolkit, other electronic records management agencies could follow the process and develop their own toolkit reflecting their situation, and utilize the self-assessment results in-house. As a result of this research, 12 areas for assessment were set, which include (organizational) operation management, classification system and master data management, acquisition, registration and description, storage and preservation, disposal, services, providing finding aids, system management, access control and security, monitoring/audit trail/statistics, and risk management. In each 12 area, the process map or functional charts were drawn and business functions were analyzed, and 54 'evaluation criteria', consisted of main business functional unit in each area were drawn. Under each 'evaluation criteria', 208 'specific evaluation criteria', which supposed to be implementable, measurable, and provable for self-evaluation in each area, were drawn. The audit and certification toolkit developed by this research could be used by digital repositories to conduct periodical self-assessment of the organization, which would be used to supplement any found deficiencies and be used to reflect the organizational development strategy.

Design of Video Pre-processing Algorithm for High-speed Processing of Maritime Object Detection System and Deep Learning based Integrated System (해상 객체 검출 고속 처리를 위한 영상 전처리 알고리즘 설계와 딥러닝 기반의 통합 시스템)

  • Song, Hyun-hak;Lee, Hyo-chan;Lee, Sung-ju;Jeon, Ho-seok;Im, Tae-ho
    • Journal of Internet Computing and Services
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    • v.21 no.4
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    • pp.117-126
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    • 2020
  • A maritime object detection system is an intelligent assistance system to maritime autonomous surface ship(MASS). It detects automatically floating debris, which has a clash risk with objects in the surrounding water and used to be checked by a captain with a naked eye, at a similar level of accuracy to the human check method. It is used to detect objects around a ship. In the past, they were detected with information gathered from radars or sonar devices. With the development of artificial intelligence technology, intelligent CCTV installed in a ship are used to detect various types of floating debris on the course of sailing. If the speed of processing video data slows down due to the various requirements and complexity of MASS, however, there is no guarantee for safety as well as smooth service support. Trying to solve this issue, this study conducted research on the minimization of computation volumes for video data and the increased speed of data processing to detect maritime objects. Unlike previous studies that used the Hough transform algorithm to find the horizon and secure the areas of interest for the concerned objects, the present study proposed a new method of optimizing a binarization algorithm and finding areas whose locations were similar to actual objects in order to improve the speed. A maritime object detection system was materialized based on deep learning CNN to demonstrate the usefulness of the proposed method and assess the performance of the algorithm. The proposed algorithm performed at a speed that was 4 times faster than the old method while keeping the detection accuracy of the old method.

VDT작업대 설계의 인간공학적 연구

  • 권영국;이성렬;민재형
    • Proceedings of the Korean Operations and Management Science Society Conference
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    • 1992.04b
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    • pp.581-591
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    • 1992
  • 최근 급속한 사무자동화와 함께 컴퓨터의 사용이 보편화되어 가지고 있다. 이에 따라 컴퓨터등 VDT에 매달려 일하는 사무직 근로자들이 시력장해, 두통, 어깨결림, 요통, 스트레스성 장애등 새로운 질병에 시달리고 있다. 이것은 "VDT증후군"(Visual Display Terminal Syndrome) 또는 "VDT병"이란 신종 직업병이다. 컴퓨터 수상기 화면을 계속해서 들여다보면 화면에서 나오는 자외선과 강한 빛으로 눈에 무리가 와 충혈되고 침침해지며 두통 증세가 나타난다. 이런 초기증상이 6개월이상 계속되면 시력이 떨어지고 만성피로를 느끼는가 하면, 때때로 독감과 비슷한 증상이 나타나며, 심하면 탈모현상까지 경험하게 된다. 요즘 시행되고 있는 초등 고교 컴퓨터교육의 의무화와 2천년대의 1가구 1단말기 설치를 목표로한 컴퓨터 영상단말기의 급속한 보급으로, 앞으로는 사무실뿐만 아니라 일반 가정에까지 컴퓨터 이용이 일상화될 전망이고 보면 VDT작업에 따른 건강장해 문제는 더이상 가볍게 볼 수 없는 문제이다. 이에 대해 선진국에서는 작업시간 규제, 회사가 종업원의 정기적인 시력검진 및 시력교정에 필요한 비용을 보조하도록 하는가하면 실작업환경 개선등 다각적인 대책을 마련하고 있다. 미국, 유럽, 일본등 선진국에서는 VDT작업 여성들의 유산 및 기형아 출산등 임신이상에 관한 실태보고서까지 나오고 있어 여성들에게 커다란 충격을 던져주고 있다. 그러나 우리나라에서는 VDT병 증상을 호소하는 근로자들의 직업병예방 및 대책에 큰 어려움을 겪고있다. 그러므로, VDT작업으로 인한 건강상의 문제, 작업환경 및 작업자세등을 조사하여 문제점과 예방대책을 살펴보고, 작업장을 인간공학적으로 설계하고 평가하여 사용자의 건강을 보호하고 생산성의 향상에 도움이 되고자 한다.생산성의 향상에 도움이 되고자 한다.Action Code를 계산처리부로 넘겨준다. 입력처리부에서는 Mouse와 Keyboard 어느것으로나 입력이 가능하도록 해준다. 출력처리부에서는 Action Code에 따라 계산처리부에서 계산된 결과를 화면에 보여주기 위한 각종 2D/3D Graphic Routine들이 포함되어있어 계산처리부에서 불러쓰도록 되어있다.에서는 전문가시스템 기법을 도입해서 사출금형 공정계획전문가의 지식과 경험을 획득하여 지식베이스를 구축하고, 전문가시스템 셀(shell)중 CLIPS를 이용하여 자동공정계획시스템인 Mold CAPP을 개발하였다.PP을 개발하였다.며 이와 상이한 결과도 보여주고 있다. 이상으로 볼 때 1) 가정하수의 질을 높이기 위하여 분뇨정화조 의 효율증대 2) 산업폐수의 공정별 폐수량의 조절 및 폐수성 상에 따른 총량규제에 대비한 효율증대 3) 하천의 오염부하와 자정능력 최대한 부여 4) 폐수처리를 위한 미생물제개발 및 오염지표 종 연구와 오염내성 생물의 연구등이 종합적 으로 수행되어야 한다. 5) 이상의 모든 조사와 연구결과를 객관적으로 표기할 수 있도록 하천의 이정표가 정해져야 하겠다.7%)에 비해 유의하게 낮았고 정상군과는 유의한 차이를 보이지 않았다.상고나성이 있었다. 혈중 호모시스테인 농도는 질병의 위험요인으로서 뿐 아니라 대사적으로 밀접하게 연관된 비타민 영양상태의 biomarker로서도 그 영향력이 크다고 할 수 있다. 따라서 성별에 다른 다양한 연령집단에서 건강한 일반인과 심혈관계 질환자 등을 대상으로 호모시스테인과 비타민 영양상태에 대한 연구가 체계적으로 이루어 져야 할 것이다.태를 보다 효율적으로 증진시킬 수 있는 대안이 마련되어져야 한다고 사료된다.$\ulcorner$순응$\lrcorner$의 범위를 벗어나지 않는다. 그렇기 때문에도

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Economic Analysis of Typhoon Surge Floodplain that Using GIS and MD-FDA from Masan Bay, South Korea (MD-FDA와 GIS를 이용한 마산만의 태풍해일 범람구역 경제성 분석)

  • Choi, Hyun;Ahn, Chang-Hwan
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.12 no.4
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    • pp.724-729
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    • 2008
  • In the case of 'MAEMI', the Typhoon which formed in September, 2003, the largest-scale damage of tidal wave was caused by the co-occurrence of Typhoon surge and full tide. Until now Korea has been focusing on the calculating the amount of damage and its restoration to cope with these sea and harbor disasters. It is essential to establish some systematic counterplans to diminish such damages of large-scale tidal invasion on coastal lowlands considering the recent weather conditions of growing scale of typhoons. Therefore, the purpose of this research is to make the counterplans for prevention against disasters fulfilled effectively based on the data conducted by comparing and analyzing the accuracy between observation values and the results of estimating the greatest overflow area according to abnormal tidal levels centered on Masan area where there was the severest damage from tidal wave at that time. It's necessary utilize data like high-resolution satellite image and LiDAR(etc.) for correct analysis data considering geographical characteristics of dangerous area from the storm surge. And we must make a solution to minimize the damage by making data of dangerous section of flood into GIS Database using those data (as stated above) and drawing correcter damage function.

Development and Application of the Slope Management Program in Urban Area (대도시 사면관리프로그램 개발 및 적용)

  • Kim, Kyeong-Su;Chae, Byung-Gon;Cho, Yong-Chan;Lee, Choon-Oh;Song, Young-Suk
    • The Journal of Engineering Geology
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    • v.17 no.1 s.50
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    • pp.15-25
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    • 2007
  • In general, the life and asset casualties that occur due to landslide or slope failure in urban areas are larger than that in rural areas. In order to reduce the casualties, a slope management program is necessary to categorize slopes based on properties and to manage them systematically. The slope management system is the establishment of the data base for the geological and geotechnical factor according to slope stability, and the utilization of the data base to manage slopes. The suitable system must develop to slopes in urban area through the survey, analysis and evaluation process. Based on the above necessity, the slope management program which is applicable to slope management in an urban area has been developed at Hwangryung Mt. in Busan as a target area. The developed slope management program has various functions such as slope ID number of each slope or sub-region of a mountain, making a slope data sheet, analysis and grouping of slope stability, and establishment of a data base. The slope management program is constructed by use of GIS, and the survey, test and analysis data according to all slopes can be input and edited into the program. The program can also be utilized practically by end users due to the convenient input, edition printing, management and operation of slope data. Therefore, the slope management system has been established on the application of the developed program in Busan which is located in slope area. As the system is widely applied to other cities, the slope in urban area can be managed systematically and the slope hazards can be minimized.