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Evaluation of the Congenital Hypothyroidism for Newborn Screening Program in Korea: A 14-year Retrospective Cohort Study (한국인 선천성 갑상선기능저하증에 대한 신생아선별검사의 14년간의 후향적 연구; 발생빈도와 유효성)

  • Yoon, Hye-Ran;Ahn, Sunhyun;Lee, Hyangja
    • Journal of The Korean Society of Inherited Metabolic disease
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    • v.19 no.1
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    • pp.1-11
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    • 2019
  • Purpose: Congenital hypothyroidism (CH) is the most common congenital endocrine disorder. The purpose of the present study was to determine the incidence of CH in South Korea during the period from January 1991 to March 2004. Methods: Central data from each city branch of SCL (Seoul Clinical Reference Laboratories) in Yongin, South Korea, was gathered and collectively analyzed. Newborn screening (NBS) for CH was based on measuring the levels of neonatal thyroid stimulating hormone (TSH) and free T4 (a cut-off of 20 mIU/L and less than 0.8 ng/dL, respectively). Results: During the study period, 671,805 live births were screened for CH based on TSH and free T4 ELISA assays. A total of 159 newborns were deemed positive for CH out of 671,805, with a corresponding incidence of 1 in 4,225. When a cut-off of 20 mIU/L was used in TSH assays, the associated sensitivity, specificity, and positive predictive values (PPV) were 100.0%, 99.7%, and 10.8%, respectively. When a cut-off of 0.8 ng/dL in free T4 assays was used, the associated sensitivity, specificity, and PPV were 100.0%, 98.5%, and 3.9%, respectively. Conclusion: CH incidence in South Korea as evidenced by the results of NBS was compared with its incidence and comparable to the other countries prior to 2004.

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The Change of Phytoplankton Community Structure and Water Quality in the Juksan Weir of the Yeongsan River Watershed (영산강수계 죽산보의 식물플랑크톤과 이화학적 변화)

  • Son, Misun;Chung, Hyeon Su;Park, Chang Hee;Park, Jong-hwan;Lim, Cheahong;Kim, Kyunghyun
    • Korean Journal of Environmental Biology
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    • v.36 no.4
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    • pp.591-600
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    • 2018
  • The objective of this study was to determine the changes in phytoplankton and long-term water quality of Juksan-Weir in Yeongsan River that took place between April 2010 and December 2015. The number of species used in this study was 288, which consisted of 6% of Cyanophyta, 26% of Bacillariophyta, 53% of Chlorophyta and the others (15%). The standing crops of phytoplankton ranged from $500cells{\cdot}mL^{-1}-29,950cells{\cdot}mL^{-1}$ with an average of $7,885cells{\cdot}mL^{-1}$. At the two site, 20 dominant genera of found. The dominant genera were 6 of Bacillariophyta, 6 of Cyanophyta, 7 of Chlorophyta and 1 of Cryptophyta. The most dominant genus among the phytoplankton was Stephanodiscus sp. (Total 59%, each 54% and 63%). The most dominant genus among the Cyanophyta was Microcystis sp., which had a cell abundance ratio of 17%. The results of two sites were 21% and 13%, and the upstream was higher than the downstream.

An investigation Of IntraFraction Motion Correction For Lung Stereotactic Body Radiation Therapy By Using IntraFraction Cone Beam Computed Tomography (폐암 환자의 정위적 체부 방사선 치료 시 IntraFraction CBCT를 이용한 치료 중 자세 오차 교정에 대한 고찰)

  • Song, Hyeong Seok;Cho, Kang Chul;Park, Hyo Kuk;Yoon, Jong Won;Cho, Jung Hee
    • The Journal of Korean Society for Radiation Therapy
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    • v.31 no.1
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    • pp.67-74
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    • 2019
  • Purpose: The purpose is to correct for position errors caused by long treatment times. By correcting the target motion that can occur during lung SBRT using IntraFraction CBCT. Methods and materials: We analyzed retrospectively the IFM data of 14 patients with two treatment arc in the treatment plan for lung cancer with stereotactic radiotherapy. An IntraFraction Motion was applied to the Arccheck phantom to acquire the Gamma index data. Results : IntraFraction Motion during the first treatment arc is in the left-right(LR), superiorinferior(SI), anterior-posterior(AP) directions were $0.16{\pm}0.05cm$, 0.72 cm(max error), $0.2{\pm}0.14cm$, 1.26 cm, $0.24{\pm}0.08cm$, 0.82 cm and rotational directions was $0.84{\pm}0.23^{\circ}$, $2.8^{\circ}$(pitch), $0.72{\pm}0.23^{\circ}$, $2.5^{\circ}$(yaw), $0.7{\pm}0.19^{\circ}$, $2^{\circ}$(roll). IntraFraction Motion during the second treatment arc is in the LR, SI, AP directions were $0.1{\pm}0.04cm$, 0.37 cm, $0.14{\pm}0.17cm$, 2 cm, $0.12{\pm}0.04cm$, 0.5 cm and rotational directions was $0.45{\pm}0.12^{\circ}$, $1.3^{\circ}$, $0.37{\pm}0.1^{\circ}$, $1^{\circ}$, $0.35{\pm}0.1^{\circ}$, $1.2^{\circ}$. Gamma index pass rates were $82.64{\pm}10.51%$, 48.4 %. Conclusions : In this study, we examined the validity of IntraFraction Motion correction in lung SBRT and the efficiency of IntraFraction CBCT. Due to the nature of SBRT treatment, IFM may increase due to the increased treatment time. It is believed that the increase in IFM with the increase in treatment time can be improved with the use of FFF Beam and additional position correction using CBCT during treatment.

Distribution and Antimicrobial Resistance of Non-Tuberculous Mycobacteria during 2015~2020: A Single-Center Study in Incheon, South Korea (2015~2020년 동안 인천 지역 단일기관에서의 비결핵항산균 분포 및 항균제 내성률)

  • Kim, Jiwoo;Ju, Hyo-Jin;Koo, Jehyun;Lee, Hyeyoung;Park, Hyeonhwan;Song, Kyungcheol;Kim, Jayoung
    • Korean Journal of Clinical Laboratory Science
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    • v.53 no.3
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    • pp.225-232
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    • 2021
  • This study sought to investigate the distribution, antimicrobial resistance rate, and bacterial co-infection frequency of non-tuberculous mycobacteria (NTM) in a single center in Incheon, South Korea. A total of 8,258 specimens submitted for tuberculosis (TB)/NTM real-time PCR tests during the years 2015 to 2020 were retrospectively reviewed. In total, 296 specimens (3.6%) were NTM positive, and the positivity increased from 2.5% (30/1,209) in 2015 to 3.8% (66/1,740) in 2020. Of 296 NTM specimens, 54.7% (162/296) were identified as the Mycobacterium avium complex (MAC) followed by the Mycobacterium abscessus complex (MABC) 20.9% (62/296), M. fortuitum 6.4% (19/296) and M. flavescens 3.4% (10/296). Of the NTM-positive specimens, 76.7% (227/296) were tested for drug resistance. The results showed multidrug-resistant NTM in 40.1% (91/227) and extensively drug-resistant NTM in 59.9% (136/227) of these specimens. Of the 145 isolates taken for bacterial culture, bacteria/fungi co-infection with NTM accounted for 43.4% (63/145), in which the most common bacterial species was Klebsiella pneumonia (23.8%, 15/63). This study is the first report on the distribution and antimicrobial resistance of NTM in Incheon. As the proportion of NTM infections increases, active treatment and thorough infection control are required for effective management.

A Study of the Application of 'Digital Heritage ODA' - Focusing on the Myanmar cultural heritage management system - (디지털 문화유산 ODA 적용에 관한 시론적 연구 -미얀마 문화유산 관리시스템을 중심으로-)

  • Jeong, Seongmi
    • Korean Journal of Heritage: History & Science
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    • v.53 no.4
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    • pp.198-215
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    • 2020
  • Official development assistance refers to assistance provided by governments and other public institutions in donor countries, aimed at promoting economic development and social welfare in developing countries. The purpose of this research is to examine the construction process of the "Myanmar Cultural Heritage Management System" that is underway as part of the ODA project to strengthen cultural and artistic capabilities and analyze the achievements and challenges of the Digital Cultural Heritage ODA. The digital cultural heritage management system is intended to achieve the permanent preservation and sustainable utilization of tangible and intangible cultural heritage materials. Cultural heritage can be stored in digital archives, newly approached using computer analysis technology, and information can be used in multiple dimensions. First, the Digital Cultural Heritage ODA was able to permanently preserve cultural heritage content that urgently needed digitalization by overcoming and documenting the "risk" associated with cultural heritage under threat of being extinguished, damaged, degraded, or distorted in Myanmar. Second, information on Myanmar's cultural heritage can be systematically managed and used in many ways through linkages between materials. Third, cultural maps can be implemented that are based on accurate geographical location information as to where cultural heritage is located or inherited. Various items of cultural heritage were collectively and intensively visualized to maximize utility and convenience for academic, policy, and practical purposes. Fourth, we were able to overcome the one-sided limitations of cultural ODA in relations between donor and recipient countries. Fifth, the capacity building program run by officials in charge of the beneficiary country, which could be the most important form of sustainable development in the cultural ODA, was operated together. Sixth, there is an implication that it is an ODA that can be relatively smooth and non-face-to-face in nature, without requiring the movement of manpower between countries during the current global pandemic. However, the following tasks remain to be solved through active discussion and deliberation in the future. First, the content of the data uploaded to the system should be verified. Second, to preserve digital cultural heritage, it must be protected from various threats. For example, it is necessary to train local experts to prepare for errors caused by computer viruses, stored data, or operating systems. Third, due to the nature of the rapidly changing environment of computer technology, measures should also be discussed to address the problems that tend to follow when new versions and programs are developed after the end of the ODA project, or when developers have not continued to manage their programs. Fourth, since the classification system criteria and decisions regarding whether the data will be disclosed or not are set according to Myanmar's political judgment, it is necessary to let the beneficiary country understand the ultimate purpose of the cultural ODA project.

Kriging of Daily PM10 Concentration from the Air Korea Stations Nationwide and the Accuracy Assessment (베리오그램 최적화 기반의 정규크리깅을 이용한 전국 에어코리아 PM10 자료의 일평균 격자지도화 및 내삽정확도 검증)

  • Jeong, Yemin;Cho, Subin;Youn, Youjeong;Kim, Seoyeon;Kim, Geunah;Kang, Jonggu;Lee, Dalgeun;Chung, Euk;Lee, Yangwon
    • Korean Journal of Remote Sensing
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    • v.37 no.3
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    • pp.379-394
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    • 2021
  • Air pollution data in South Korea is provided on a real-time basis by Air Korea stations since 2005. Previous studies have shown the feasibility of gridding air pollution data, but they were confined to a few cities. This paper examines the creation of nationwide gridded maps for PM10 concentration using 333 Air Korea stations with variogram optimization and ordinary kriging. The accuracy of the spatial interpolation was evaluated by various sampling schemes to avoid a too dense or too sparse distribution of the validation points. Using the 114,745 matchups, a four-round blind test was conducted by extracting random validation points for every 365 days in 2019. The overall accuracy was stably high with the MAE of 5.697 ㎍/m3 and the CC of 0.947. Approximately 1,500 cases for high PM10 concentration also showed a result with the MAE of about 12 ㎍/m3 and the CC over 0.87, which means that the proposed method was effective and applicable to various situations. The gridded maps for daily PM10 concentration at the resolution of 0.05° also showed a reasonable spatial distribution, which can be used as an input variable for a gridded prediction of tomorrow's PM10 concentration.

A Survey of Yeosu Sado Dinosaur Tracksite and Utilization of Educational Materials using 3D Photogrammetry (3D 사진측량법을 이용한 여수 사도 공룡발자국 화석산지 조사 및 교육자료 활용방안)

  • Jo, Hyemin;Hong, Minsun;Son, Jongju;Lee, Hyun-Yeong;Park, Kyeong-Beom;Jung, Jongyun;Huh, Min
    • Journal of the Korean earth science society
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    • v.42 no.6
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    • pp.662-676
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    • 2021
  • The Yeosu Sado dinosaur tracksite is well known for many dinosaur tracks and research on the gregarious behavior of dinosaurs. In addition, various geological and geographical heritage sites are distributed on Sado Island. However, educational field trips for students are very limited due to accessibility according to its geological location, time constraints due to tides, and continuous weathering and damage. Therefore, this study aims to generate 3D models and images of dinosaur tracks using the photogrammetric method, which has recently been used in various fields, and then discuss the possibility of using them as paleontological research and educational contents. As a result of checking the obtained 3D images and models, it was possible to confirm the existence of footprints that were not previously discovered or could not represent details by naked eyes or photos. Even previously discovered tracks could possibly present details using 3D images that could not be expressed by photos or interpretive drawings. In addition, the 3D model of dinosaur tracks can be preserved as semi-permanent data, enabling various forms of utilization and preservation. Here we apply 3D printing and mobile augmented reality content using photogrammetric 3D models for a virtual field trip, and these models acquired by photogrammetry can be used in various educational content fields that require 3D models.

Observation of Ice Gradient in Cheonji, Baekdu Mountain Using Modified U-Net from Landsat -5/-7/-8 Images (Landsat 위성 영상으로부터 Modified U-Net을 이용한 백두산 천지 얼음변화도 관측)

  • Lee, Eu-Ru;Lee, Ha-Seong;Park, Sun-Cheon;Jung, Hyung-Sup
    • Korean Journal of Remote Sensing
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    • v.38 no.6_2
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    • pp.1691-1707
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    • 2022
  • Cheonji Lake, the caldera of Baekdu Mountain, located on the border of the Korean Peninsula and China, alternates between melting and freezing seasonally. There is a magma chamber beneath Cheonji, and variations in the magma chamber cause volcanic antecedents such as changes in the temperature and water pressure of hot spring water. Consequently, there is an abnormal region in Cheonji where ice melts quicker than in other areas, freezes late even during the freezing period, and has a high-temperature water surface. The abnormal area is a discharge region for hot spring water, and its ice gradient may be used to monitor volcanic activity. However, due to geographical, political and spatial issues, periodic observation of abnormal regions of Cheonji is limited. In this study, the degree of ice change in the optimal region was quantified using a Landsat -5/-7/-8 optical satellite image and a Modified U-Net regression model. From January 22, 1985 to December 8, 2020, the Visible and Near Infrared (VNIR) band of 83 Landsat images including anomalous regions was utilized. Using the relative spectral reflectance of water and ice in the VNIR band, unique data were generated for quantitative ice variability monitoring. To preserve as much information as possible from the visible and near-infrared bands, ice gradient was noticed by applying it to U-Net with two encoders, achieving good prediction accuracy with a Root Mean Square Error (RMSE) of 140 and a correlation value of 0.9968. Since the ice change value can be seen with high precision from Landsat images using Modified U-Net in the future may be utilized as one of the methods to monitor Baekdu Mountain's volcanic activity, and a more specific volcano monitoring system can be built.

Exploring the Trend of Korean Creative Dance by Analyzing Research Topics : Application of Text Mining (연구주제 분석을 통한 한국창작무용 경향 탐색 : 텍스트 마이닝의 적용)

  • Yoo, Ji-Young;Kim, Woo-Kyung
    • Journal of Korea Entertainment Industry Association
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    • v.14 no.6
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    • pp.53-60
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    • 2020
  • The study is based on the assumption that the trend of phenomena and trends in research are contextually consistent. Therefore the purpose of this study is to explore the trend of dance through the subject analysis of the Korean creative dance study by utilizing text mining. Thus, 1,291 words were analyzed in the 616 journal title, which were established on the paper search website. The collection, refining and analysis of the data were all R 3.6.0 SW. According to the study, keywords representing the times were frequently used before the 2000s, but Korean creative dance research types were also found in terms of education and physical training. Second, the frequency of keywords related to the dance troupe's performance was high after the 2000s, but it was confirmed that Choi Seung-hee was still in an important position in the study of Korean creative dance. Third, an analysis of the overall research subjects of the Korean creative dance study showed that the research on 'Art of Choi Seung-hee in the modern era' was the highest proportion. Fourth, the Hot Topics, which are rising as of 2000, appeared as 'the performance activities of the National Dance Company' and 'the choreography expression and utilization of traditional dance'. However, since the recent trend of the National Dance Company's performance is advocating 'modernization based on tradition', it has been confirmed that the trend of Korean creative dance since the 2000s has been focused on the use of traditional dance motifs. Fifth, the Cold Topic, which has been falling as of 2000, has been shown to be a study of 'dancing expressions by age'. It was judged that interest in research also decreased due to the tendency to mix various dance styles after the establishment of the genre of Korean creative dance.

Study on Horizontal and Vertical Temperature Analysis of Cable Fire in Common Duct using Room Corner Experiment (룸코너 실험을 이용한 공동구 케이블 화재 시 수평·수직 방향 온도 분석에 관한 연구)

  • JaeYeop Kim;SeHong Min
    • Journal of the Society of Disaster Information
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    • v.19 no.3
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    • pp.634-643
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    • 2023
  • Purpose: Underground common duct fires are steadily occurring, and the proportion of property damage is particularly large among property and human casualties caused by fires. Especially, cable fires that occur in common areas can spread vertically quickly and pose a great risk. This paper aims to scientifically analyze the nature of the fire by reproducing the fire through experiments. Method: To analyze the characteristics of cable fires in underground common duct, heat release rate and temperature changes were measured through Room-corner (ISO 9705) test, and the vertical and horizontal propagation of cable fires was quantitatively compared and analyzed. Result: The Room Corner Test (ISO 9705) was used to compare the temperature changes at each data logger point. The results showed that the time it took for the fire to reach the ignition temperature in the horizontal and vertical directions from the center point of the first-tier cable was 589 seconds and 536 seconds, respectively, which means that the vertical fire propagation is 53 seconds faster than the horizontal propagation. This proves that the vertical propagation of fire is relatively faster than the horizontal propagation. The horizontal propagation speed of the fire was also compared for each floor cable tray. The results showed that the third-tier cable propagated at 3.4 times the speed of the second-tier cable, and the second-tier cable propagated at 1.5 times the speed of the first-tier cable. This means that the higher the cable is located, the faster the fire spreads and the larger the fire becomes. Conclusion: This study identified the risks of cable fires and analyzed the risks of vertical fire propagation during cable fires based on the results of the Room Corner Test. Studies to prevent the spread of fire and fire response policies to prevent vertical fire propagation are required. The results of this study are expected to be used to assess the fire risk of common areas and other fires.