• Title/Summary/Keyword: 위장암

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Reduction Effect of Carcinogen-induced Mouse Epidermal and Forestomach Carcinogenesis by the Extract of Onion Wastes (비상품 양파추출물의 Mouse 피부암 및 위장안 억제효과)

  • 이찬중;김희대;정은호;서전규;박철우;하영래
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.29 no.3
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    • pp.525-530
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    • 2000
  • 상품가치가 없는 비상품구로부터 추출한 OWE를 mouse의 피부암 및 위장암 저해 효과에 관한 실험을 한 결과 피부암의 경우 control구에서는 6주부터 종양이 발생하여 23주에는 mouse 당 2.9개의 종양이 발생하였으나 20mg OWE 처리구에서는 8주부터 종양이 발생하여 23주에는 mouse 당 1.3개의 종양이 발생하여 control에 비해 55.2%의 종양 억제효과가 있었다. 20mg quercetin 처리에서는 6주부터 종양이 발생하기 시작하여 23주에는 mouse 당 1.2개의 종양이 발생하였다. 처리별 암 발생율은 20mg OWE 처리에서 85.7%, 20mg quercetin 처리에서는 76.2%의 발생율을 보여 control의 95.2%에 비해 낮은 암발생율을 보였다. 위장암의 경우 control에서는 mouse 당 9.2개의 종양이 발생하였고, 50mg OWE 및 25mg OWE 처리에서는 각 6.1, 6.3개의 종양이 발생하여 control에 비해 각각 33.7%, 31.5%의 종양억제효과가 있었다. 그리고 25mg quercetin 처리에서는 mouse 당 5.3개의 종양이 발생하였다. 처리별 암발생율은 50mg OWE 및 25 mg OWE 처리에서 각 88.2%, 94.1%, 25mg quercetin 처리에서 83.3%의 발생율을 보여 control 100%에 비해 낮은 암발생율을 보였다.

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Composite Graft Reconstruction of Esophagus for Double Primary Cancer of Larynx & Esophagus (후두암과 식도암의 이증원발성 종양에서의 합이식술을 이용한 식도 재건술)

  • I Hoseok;Song Dong Seop;Kim Su Wan;Shim Young Mog
    • Journal of Chest Surgery
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    • v.38 no.11 s.256
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    • pp.791-794
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    • 2005
  • After esophagectomy, the stomach is used most commonly for the method of reconstruction. However, the stomach may not be large enough to be reached the site of anastomosis when it is above the pharynx. We experienced a double primary cancer of the lower esophagus and the larynx. Total laryngectomy and total esophagectomy were done with cervical pharyngojejunogastrostomy for reconstruction. Free jejunal graft is interposed between the oropharyngeal stump and the stomach is pulled-up. We could restore the alimentary track without tension at the anastomotic site and obtain sufficient blood supply.

Carcinoma of the Colon and Rectum : Sonographic Findings and usefulness (Cases Review) (결직장암의 초음파검사 소견 및 유용성(증례 중심으로))

  • Jung, Hong-Ryang;Kim, Myeong-Soo;Sim, Hyun-Sun
    • Journal of radiological science and technology
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    • v.26 no.2
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    • pp.43-47
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    • 2003
  • Colorectal cancer produce focal mass or segmental thickening which can be detected with sonography. The purpose of this study was to describe sonographic findings of colorectal cancer. we reviewed sonograms of 51 patients with colorectal cancer in whom sonography was performed before colon study. In 51 patients who had more common coloretal cancer 27cases(53%) had 40 to 50 years of age(60%). Sonographic findings included segmental thickening 42cases, or irregular mass 9 cases. With careful examination, these findings can be detectable, and therefore bowel should be carefully examination in patients with sign and symptoms suggesting carcinoma of the colon and rectum.

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숫자로 본 메디체크 - 정확성 높은 메디체크 위장 및 대장 질환 검진

  • 한국건강관리협회
    • 건강소식
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    • v.38 no.9
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    • pp.4-5
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    • 2014
  • 한국건강관리협회 메디체크는 높은 흡연율, 잦은 술자리와 각종 스트레스, 운동부족이라는 건강위험요소에 노출된 현대인들의 건강을 지키고자 정확하고 체계적인 위 대장 검진 서비스를 제공하고 있다. 위장 및 대장 질환 중에서도 위암과 대장암은 조기에 발견해야 완치율이 높아지기 때문에 정기적으로 건강검진을 받는 것이 무엇보다 중요하다. 이 외에도 메디체크는 위장 및 대장 질환 유소견자나 경계인의 건강회복을 위해 식습관 및 생활습관 상담을 실시하는 등 국민건강증진에 앞장서고 있다.

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Clinical Prognostic Factors of Terminal Cancer Patients with Palliative Procedures for Malignant Gastrointestinal Obstruction (완화적 시술을 받은 악성 위장관 폐색 말기 암환자의 임상적 예후인자)

  • Moon, Do-Ho;Choe, Wha-Sook
    • Journal of Hospice and Palliative Care
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    • v.8 no.2
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    • pp.200-208
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    • 2005
  • Purpose: Palliative procedures or surgical interventions not only manage various symptoms of malignant gastrointestinal obstruction, but also improve the quality of life. We investigated the clinical characteristics and prognostic factors of terminal cancer patients with palliative procedures for malignant gastrointestinal obstruction. Methods: We retrospectively reviewed the medical records of 48 terminal cancer patients with palliative procedures for malignant gastrointestinal obstruction at Sam Anyang hospital from May in 2002 to May in 2005. We excluded patients with palliative tumor resection. We analyzed prognostic factors in symtom-free survival and overall survival using Kaplan-Meier method, univariate and multivariate analysis. Results: There were 25 males (52%) and 23 females (48%), and median age of 48 patients was 65 years. The most common cause of malignant gastrointestinal obstruction was colorectal (26 patients, 55%), followed by stomach (10, 21%). Twenty patients (42%) received previous treatment (chemotherapy, surgery, and radiotherapy) and 28 (58%) never received any. Eighteen of 20 had received chemotherapy. The most common symptom was pain (15 patients, 31%). Twenty three patients (48%) had Eastern Cooperative Oncology Group(ECOG) performance status of 1 or 2 score and 25 patients (52%) 3 or 4 score. The most common palliative procedure was colostomy and there was no mortality concerning the palliative procedures. By univariate and multivariate analysis, performance status was the only independent prognostic factor in overall survival and symptom-free survival. Overall survival was 150 days and symptom-free survival was 90 days. Conclusion:. We confirmed that perftatdormance status is significant independent prognostic factor in terminal cancer patients with palliative procedures for malignant gastrointestinal obstruction.

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Photodynamic Therapy for Neoplasms in Intrathoracic Constructed Stomach (식도암 수술 후 흉곽 내 위장에 발생한 원발성 위암에 대한 광역동치료 -1예 보고 -)

  • Park, Ki-Sung;Ko, Moo-Sung;Kwon, Oh-Choon;Lee, Sub;Kim, Jong-Ki;Jheon, Sang-Hoon
    • Journal of Chest Surgery
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    • v.36 no.10
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    • pp.794-797
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    • 2003
  • Photodynamic therapy (PDT) is a local, endoscopically controlled nonoperative therapeutic technique based on selective sensitization of mucosal, malignant and precancerous lesions of the esophagus, trachea and bronchus prior to light-induced tissue destruction in the department of thoracic and cardiovascular surgery. PDT is effective and safe for palliative treatment of neoplasms in the stomach, esophagus, and lung. But skin phototoxicity is unsatisfactory, therefore optimization of management of post-PDT is necessary for preventing phototoxic side effects of skin. Careful patient education in photoprotection techniques, close patient follow-up, early dermatologic referral and medical treatment are recommended. We performed PDT in a patient with intrathoracic constructed stomach. We report this case with a brief review of literatures, therefore.

Synchronous Occurrence of a Gastric Adenocarcinoma and a GIST (Gastrointestinal Stromal Tumor): A Case Report (위에 동시성으로 발생한 조기위암 및 위장관간질종양)

  • Jee, Sung-Bae;Seo, Kyung-Jin;Heo, Hun;Jeon, Hae-Myung
    • Journal of Gastric Cancer
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    • v.7 no.4
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    • pp.261-264
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    • 2007
  • A gastric adenocarcinoma is the second most common cause of cancer deaths worldwide, but there are some geographical differences in its incidence. A gastrointestinal tumor is an uncommon disease with a wide spectrum of aggressive behavior. These two tumors have a distinct pathogenesis, and synchronous occurrence of an adenocarcinoma and a GIST (gastrointestinal stromal tumor) in the stomach is very rare. We report a case of synchronous occurrence of a gastric adenocarcinoma and GIST in a 64-year-old man. We performed the following tests: barium swallowing test, gastroduodenoscopy, and CT scanning. We performed a total gastrectomy, and a 9 em-sized GIST at the fundus and a small early gastric cancer at the antrum were confirmed pathologically. Some explanations for this rare case exist, but in our opinion, the synchronous occurrence is a rare but probable event that can happen in an endemic area. We describe a case of synchronous occurrence of a gastric adenocarcinoma and GIST in the stomach, with a review of the literature.

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Cervical Esophagogastric Anastomosis with Endo Stapler (흉강경용 봉합기를 이용한 경부 식도위 문합술)

  • 김광택;손호성
    • Journal of Chest Surgery
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    • v.29 no.9
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    • pp.1003-1009
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    • 1996
  • Although esophagogastric (EG) anastomosis with a circular surgical stapler (EEA or ILS) is a safe find convenient proc dure with less anastomotic leakage, a concern for the anastomotic stricture still remains, especially in patients with small esophagus. We modified cervical EG anastomotic technique using straight thoracoscopic endostapler to prevent EG anastomotic stricture. Prospective clinical study was performed to determine the feasibility of our modification using Endo-GIA (US Surgical Corp., Worwalk), during the period from October, 1994 to July, 1995, in thirteen patients with carcinoma of the thoracic esophagus. A stomach tube was reanastomosed to the cervical esophagus utilizing a 30 mm Endo-GIA after esophagectomy and node dissection. There was one early mortality due to respiratory failure and pulmonary tuberculosis. Anastomotic leakage with resultant stricture was noticed in one patient, and it was re- lated to ischemic necrosis of the stomach tube. The overall incidence of stricture was 7.6 % (1113). During the 8 month follow-up period, the remaining 11 patients did not show any clinica evidence of stricture such as dysphagia. All patients were on a regular diet. We conclude that our new technique for cervical EG anastomosis with GIA-Endo stapler is a safe and convenient procedure in preventing anastomotic stricture.

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Recurrent Gastrobronchial Fistula after Esophagectomy -one case report- (식도암 적출술후 발생한 재발성 위-기관지 누공)

  • 임수빈;조재일
    • Journal of Chest Surgery
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    • v.34 no.2
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    • pp.189-193
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    • 2001
  • 위기관지 누공은 매우 드문 질환으로 대부분의 경우 외상, 상부위장관 수술, 횡경막하 농양, 양성 위궤양, 신생물 등 이 원인으로 생각된다. 식도암의 Ivor Lewis 수술후 2년과 3년에 양성 위궤양으로 인해 발생한 재발성 위기관지 누공 1예를 문헌고찰과 함께 보고하는 바이다.

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