Photodynamic Therapy for Neoplasms in Intrathoracic Constructed Stomach

식도암 수술 후 흉곽 내 위장에 발생한 원발성 위암에 대한 광역동치료 -1예 보고 -

  • Park, Ki-Sung (Dept. of Thoracic and Cardiovascular Surgery, School of Medicine, Catholic University of Daegu) ;
  • Ko, Moo-Sung (Dept. of Thoracic and Cardiovascular Surgery, School of Medicine, Catholic University of Daegu) ;
  • Kwon, Oh-Choon (Dept. of Thoracic and Cardiovascular Surgery, School of Medicine, Catholic University of Daegu) ;
  • Lee, Sub (Dept. of Thoracic and Cardiovascular Surgery, School of Medicine, Catholic University of Daegu) ;
  • Kim, Jong-Ki (Dept. of Biomedical Engineering, Radiology, School of Medicine, Catholic University of Daegu) ;
  • Jheon, Sang-Hoon (Dept. of Thoracic and Cardiovascular Surgery, School of Medicine, Catholic University of Daegu)
  • 박기성 (대구가톨릭대학교 의과대학 흉부외과학교실) ;
  • 고무성 (대구가톨릭대학교 의과대학 흉부외과학교실) ;
  • 권오춘 (대구가톨릭대학교 의과대학 흉부외과학교실) ;
  • 이섭 (대구가톨릭대학교 의과대학 흉부외과학교실) ;
  • 김종기 (대구가톨릭대학교 의과대학 의공학교실, 방사선과학교실) ;
  • 전상훈 (대구가톨릭대학교 의과대학 흉부외과학교실)
  • Published : 2003.10.01

Abstract

Photodynamic therapy (PDT) is a local, endoscopically controlled nonoperative therapeutic technique based on selective sensitization of mucosal, malignant and precancerous lesions of the esophagus, trachea and bronchus prior to light-induced tissue destruction in the department of thoracic and cardiovascular surgery. PDT is effective and safe for palliative treatment of neoplasms in the stomach, esophagus, and lung. But skin phototoxicity is unsatisfactory, therefore optimization of management of post-PDT is necessary for preventing phototoxic side effects of skin. Careful patient education in photoprotection techniques, close patient follow-up, early dermatologic referral and medical treatment are recommended. We performed PDT in a patient with intrathoracic constructed stomach. We report this case with a brief review of literatures, therefore.

광역동치료는 흉부외과 영역에서 조기 식도암, 기관 및 기관지 종양, 위장관 점막 내 종양 및 바레트식도 등에서 광감작물질의 광파장 및 광선의 암세포에 대한 선택적이고 직접적인 독성 효과를 이용한 비수술적 치료로 안전하고 효과가 있으며, 기타 진행된 폐암이나 식도암에서 보존적 요법으로도 이용될 수 있다고 여겨지고 있다. 그러나 광역동치료 후 광독성에 의한 피부 독성이 흔하여, 직사 광선의 차단 및 약물 요법이 병행되어야 한다. 저자들은 식도암 수술 후 흘곽 내에 거치된 위장에 발생한 원발성 위암에 대한 광역동치료(Photodynamic tharapy)로 좋은 결과를 얻었기에 문헌 고찰과 함께보고하고자 한다.

Keywords

References

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