• Journal of the Korean Society of Food Science and Nutrition
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• v.33 no.7
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• pp.1206-1211
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• 2004

This study was conducted to evaluate the effects of selenium binding yeast peptide supplementation on growth performance, tissue Se, serum glutathione peroxidase activity and meat quality in finishing pigs. A total of eighty (Duroc${\times}$Yorkshir${\times}$Landrace) pigs (82.88$\pm$1.23 kg average initial body weight) were used in a 35-day assay. Dietary treatments included 1) CON (basal diet), 2) SY1 (CON diet＋0.05％ selenium binding yeast peptide), 3) SY2 (CON diet＋0.l％ selenium binding yeast peptide) and 4) SY3 (CON diet＋0.2％ selenium binding yeast peptide). Overall period, average daily gain of pigs fed selenium binding yeast peptide diet was higher than that of pigs fed CON diet, however, there was not significant difference (p＞0.05). L＊ (lightness) value of M. longissimus dorsi was higher in SY2 than CON and SY3 (p＜0.05). a＊ (redness) value of M. longissimus dorsi was lower in CON than other treatments (p＜0.05). Selenium content in serum was increased as adding selenium binding yeast peptide compared to pigs fed CON diet. However, there was not significantly different among the treatments (p＞0.05). Selenium content of M. longissimus dorsi was higher in SY2 (0.021 $\mu$g/g) and SY3 (0.031 $\mu$g/g) than CON diet (0.008 $\mu$g/g) (p＜0.05). Selenium content of kidney was increased in SY2 I and SY3 compared to pigs fed CON and SY1 (p＜0.05). Selenium content of liver was higher in SY1 than CON (p＜0.05). In conclusion, it is suggested that selenium content could be accumulated in M. longissimus dorsi, kidney and liver by selenium binding yeast peptide supplementation, and meat color of M. longissimus dorsi could be affected by selenium binding yeast peptide supplementation.

• The Journal of Korean Academy of Prosthodontics
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• v.48 no.4
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• pp.259-265
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• 2010

Purpose: This study was aimed to evaluate the effect of different sizes of $\beta$-TCP/ HA particles on vertical bone augmentation using titanium mesh in the cranium of rabbits. Materials and methods: Six white rabbits weighing 5kg were used. Four circular grooves of 6mm diameter were made by trephine, and five small holes were drilled in the inner surface of each circular gooves. Different sizes of grafts (small 0.3 - 0.5 mm, medium 0.5 - 1.0, large 1.0 - 2.0 mm) were placed respectively in the experimental groups. Titanium mesh (height 3 mm, width 6 mm) was placed. After 8weeks healing period, the rabbits were euthanized, and the specimens were prepared for histological findings. New bone formation and remaining graft area were measured to calculate the ratio of areas occupying the inner space of titanium mesh. Mann-Whitney U-test and Wilcoxon signed rank-test were used for statistical analysis ($\alpha$ = .05). Results: The experimental groups with $\beta$-TCP/HA graft showed a significantly higher new bone formation (P = .003). Comparing different sizes of $\beta$-TCP/HA, there was no statistical difference in terms of new bone formation. The vertical bone formation (i.e. new bone and graft area) was significantly greater in $\beta$-TCP/HA groups (P = .001). In comparison between different sizes of $\beta$-TCP/HA, medium size group had significantly greater area than large particle size group (P = .039). Conclusion: The use of $\beta$-TCP/HA with titanium mesh showed a higher vertical bone formation, particularly the medium sized $\beta$-TCP/HA particles (0.5 - 1.0 mm) produced better results in vertical bone augmentation.

• 한국HCI학회:학술대회논문집
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• 2009.02a
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• pp.1363-1373
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• 2009

본 연구는 두 집단지성의 가장 대표적인 서비스인 네이버 지식iN과 위키피디아의 구조적, 경험적 차이를 바탕으로 생산의 차원에서 생산 주기, 생산 참여자, 생산물의 모델을 설정하고, 새롭게 탄생하는 지식을 중심으로 검증함으로써 최종 지식 소비 행위를 반영한 각각의 종합모델을 도출하였다. 우리는 웹에서 집단지성의 일상화를 확인할 수 있다. 지식 획득 매체가 매스미디어에서 인터넷으로 변화하는 과정에서 등장한 포털 및 검색사이트는 지식의 생산이 전문가패러다임에서 소비자 중심으로 재편될 수 있는 가능성을 열어주었다. 그리고 이러한 생산 방식의 변화는 '지식'의 개념 역시 변화시키고 있다. 즉, 집단지성이라는 새로운 웹2.0의 현상이 지식생산방식을 변화시키고 변화된 지식생산방식은 '지식'자체를 변화시킨다는 이론적 가설을 도출할 수 있는 것이다. 본 연구는 이러한 새로운 현상들을 분석하기 위해서는 먼저 보다 엄밀하게 집단지성의 개념을 규정할 필요성에 출발하였다. 현재 집단지성이라는 이름으로 불리면서 급격히 성장하고 있는 위키 방식의 인터넷 서비스와 지식검색 방식의 인터넷 서비스를 비교함으로써 보다 정교한 집단지성의 모델을 구축하고자 하였다. 위키형 집단지성과 지식검색형 집단지성의 차이점은 경험적으로도 뚜렷하게 확인할 수 있다. 본 연구는 이러한 경험적 차이와 기존의 문헌에서 밝혀진 사실들을 바탕으로 두 서비스의 지식생산 방식을 생산플로우, 생산참여자 성향, 생산물(지식)의 성향과 같이 세 영역으로 나누어 각각의 가설 모델을 설정하고 이 모델을 선정된 질의어를 바탕으로 검증한 뒤에 최종적인 모델을 도출하는 방식으로 진행되었다. 지식검색형 집단지성은 '질문-답변-채택'의 구조이고, 그 구조 속에서 '질문기-답변기-순서화기'를 거쳐 하나의 지식 덩어리인 'K-let'을 생산한다. 생산된 'K-let'들은 지식검색서비스의 데이터베이스에 축적되고, 이는 공통된 질의어를 기준으로 소비자들에 의해서 검색되어 소비된다. 하나의 질문에 대해 여러 개의 답변들이 존재하고, 답변자의 성향은 크게 전문성과 체계성을 바탕으로 한 전문가형 답변자와 경험적이고 의견지향적인 대화형 답변자로 나눠진다. 다수의 네티즌들의 참여에 의해서 지식의 생산이 진행되므로 질문의 성향 역시 사실, 의견, 경험 등 다양한 스펙트럼을 가지는 모델로 설정하였다. 반면에 위키형 집단지성은 개방형 플랫폼을 바탕으로 한 백과사전의 형식이며, 이러한 형식 속에서 최초의 개념어 등록과 다수의 편집활동을 거치면서 완성되지 않는 하나의 아티클인 'W-let'을 생산한다. 이러한 'W-let'은 생성 초기에 소수에 의한 활발한 내용 입력 활동으로 어느 정도의 안정화를 거친 후에는 꾸준한 다수의 수정활동을 통해서 'W-let'의 생명력을 유지함으로써 지식의 실제적인 변화를 반영한다. 생산된 'W-let'들은 위키형 집단지성 서비스의 데이터베이스에 축적되고, 이것들은 내부링크를 통해서 모두 연결되어 있다. 백과사전 형식으로 하나의 개념어를 설명하는 하나의 아티클은 오로지 사실적인 지식들로만 구성되나 내부링크와 외부링크를 통해서 다양한 스펙트럼을 가지는 모델로 설정하였다. 위와 같이 설정된 모델을 바탕으로 공통된 질의어 및 개념어를 선정하여 각각의 서비스에 노출시켰다. 이를 통해서 얻어진 각 서비스의 데이터베이스에 축적된 모든 데이터들 중에서 일정한 기간을 기준으로 각각의 모델 검증에 필요한 데이터를 추출하여 분석하는 방식으로 진행되었다. 그 결과 지식검색형 집단지성에서는 '질문-답변-채택'의 생산 구조 속에 다수가 참여하여 질문-채택답변-기타답변으로 배열되어 있는 완성된 형태의 K-let들을 지속적으로 생산하며 비슷한 성향을 가진 K-let들이 반복적으로 생산되어 지식검색 데이터베이스에 누적된다. 지식 소비자들은 질의어 검색을 통해서 다양한 K-let들을 선택하여 비교, 검토한 후에 선택된 K-let들의 배열은 해체되어 소비자들에 의해서 재배열됨을 발견할 수 있었다. 이에 지식검색형 집단지성이란 다수의 의해서 생산되고 누적된 지식들이 소비자의 검색과 선택에 의해 해체되어 재배열되는 지식의 맞춤화 과정이라고 정의내릴 수 있었다. 반면에 위키형 집단지성에서는 '내용입력-미세수정' 구조 속에서 생명력 있는 W-let을 생성한다. W-let은 백과사전처럼 정리되어 내부링크를 통해서 서로 연결되고, 외부링크를 통해 확장되고, 지식소비자들은 검색을 통해 최초의 W-let에 도달한 후에 링크를 선택함으로써 지식을 확장시킴을 검증할 수 있었다. 따라서 위키형 집단지성이란 다수의 의해서 생산되고 정리된 지식들이 소비자의 검색과 링크에 의해 무한히 확장되는 지식의 확대 재생산되는 과정이라고 정의 내릴 수 있다. 결국, 현재의 집단지성이란 지식이 다수의 참여로 생산됨으로써 개인에게 맞춤화되고, 끊임없이 확대 재생산되는 과정을 의미한다. 그리고 이러한 집단지성의 방식은 지식이라는 현재의 차원을 넘어서 정치, 경제를 비롯한 사회의 전 영역으로 점차적으로 확대되어갈 것이다. 앞으로 연구들은 두 가지 모델이 혼재되어 있는 현재의 집단지성이 어떠한 새로운 모델을 만들면서 다른 영역으로 확장되어갈 것인지에 대해서 초점을 맞춰 나가야할 것이다.

• Journal of Mushroom
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• v.12 no.4
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• pp.263-269
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• 2014

Although sawdust cultivation of shiitake (Lentinula edodes) is becoming more common, it is insufficiently competitive in spring and autumn, the best time to breed shiitake. Thus, it is urgently needed to develop a technique for all year round cultivation of shiitake using mushroom growing beds. In the present study, the temperature changes according to the location of shiitake cultivation facilities were investigated. We confirmed that a refrigerator, an air conditioner, triple membranes, shiitake cultivation beds, fog nozzles which were installed in the shiitake cultivation facilities play an important role in keeping the low temperature. Bag cultivation of shiitake was tested in temperature variation from $14^{\circ}C$ to $29^{\circ}C$ with a $3^{\circ}C$ interval to know its cultivating temperature range in hot summer season. In summary, the sawdust cultivation of shiitake is possible when the temperature difference between top and bottom is maintained below $1^{\circ}C$. And the temperature of the shiitake cultivation facilities should be maintained below $23^{\circ}C$ in the induction period for fruitbody formation.

• Korean Journal of Soil Science and Fertilizer
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• v.25 no.4
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• pp.342-356
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• 1992

Kinetic studies using stirred-flow methods were conducted with the Luisiana soil at three pH levels(pH 5, 6.5, and 8) and three temperature levels(10, 25, and $40^{\circ}C$) to explore effects on the rate of silica retention and release and to find out reaction mechanisms. In this study the maximum silica retention could not be obtained for long enough experimental time. The silica sorption isorption was C type fitted well to Freundlich equation. The pH of the soil suspension increased by the silica release process at low pH treatments(pH 5 and 6.5), while decreased at high pH treatment(pH 8). From the above findings It can be deduced that the mechanism of silica retention is a multilayer forming process to change the ligand form depending on pH condition. In the proposed mechanism the sorbed silica provide new binding sites for additional sorption of silica, while the activation energy for the formation of subsequent layers increases correspondingly. The silica retention and release process were well described by first-order and parabolic diffusion equation. However, clear interpretation for silica sorption mechanism using these equations could not be made. The validity of the fraction term (Fa and Fd) included in first-order and parabolic diffusion equation requires further examinations because the temperature effect on apparent rate constant shows no constant trends among temperature treatments, while there was a good trend in Elovich and modified Freundlich equation where the fraction term was not included.

• Journal of Chest Surgery
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• v.29 no.1
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• pp.24-31
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• 1996

Between January 1992 and February 1995, 36 patients with mitral regurgitation were treated by a mitral repair There wert nineteen men and seventeen women whose mean age was 41.8 years, ranged from 10 to 71. Seventeenth patients had dystrophic change of mitral valve, twelve patients had rheumatic change of mitral valve, second patients had infective change of mitral valve and another fifth patients had functional change of mitral valve. Operation proced res were suture annuloplasty (35 cases), resection of leaflet (25 cases), chordal shortening(9 cases) and commisurotomy(1 cases). These procedures were combined in most patients. Two third of the patients were in New York Heart Association class III or IV and four fifth of the patients were in mitral regurgitation grade III or IV by doppler echocardiogram. After mitral valve repair, the patients were improved hemodynamic, echocardiographic data and functional class. Intraoperative TEE had been used in all most patients after weaning of bypass. If there remained MR more than grade 2, the valve was re-repaired or replacement. There were no operative death. The late mortality was 5.5% and cause of death was congestive heart failure. Patients have been followed up from 3 to 40 months, mean 15. Second patients underwant reoperation due to recurred mitral regurgitation, 4 and 19 days after the operation. During reoperation, we found that the repair suture was disrupted in both patients. Th s expierence demonstrated that intraoperative TEE is accurate and predictable and excellent immediate and mid-term results have been achieved by mitral valve repair.

• Development and Reproduction
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• v.12 no.1
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• pp.1-8
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• 2008

Specific protocols to increase the differentiation of neuronal cells from embryonic stem (ES) cells have been well established, such as retinoic acid induction and lineage selection of neuronal cells. For the neuropathological studies, ES-derived neurons (ES neurons) must show normal physiological characteristics related to cell death and survival and should be maintained in vitro for a sufficient time to show insults-specific cell death without spontaneous death. When mouse ES cells were plated onto astrocytes monolayer after retinoic acid induction, most ES cells differentiated into neuronal cells, which were confirmed by the presence of specific neuronal markers, and the cultures were viable for at least four weeks. When these cultures were examined for vulnerability to glutamate excitotoxicity, ES neurons were vulnerable to excitotoxic insults mediated by agonist-specific receptors. The vulnerability to excitotoxic death increased with developmental age of ES neurons in vitro. Specific receptors for Neurotrophin and GDNF family ligands were present in ES neurons. GDNF and NT-3 could modulate the survival and excitotoxic vulnerability of ES neurons. The vulnerability and resistance to toxic insults, which are essential requirements of model culture systems for neuropathological studies, make ES neurons to a useful model culture system. Especially ES cell are highly amenable to genetic modification unlikely to primary neuronal cells, which will give us a chance to answer more complicated neurophysiological questions. Recently there was an outstanding attempt to explore the cellular toxicity using human ES cells (Schrattenholz & Klemm, 2007) and it suggested that ES cells could be a new model system for neurophysiological studies soon and go further a large-scale screening system for pharmacological compounds in the future.

• Journal of the Korean Society of Fisheries and Ocean Technology
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• v.38 no.2
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• pp.129-139
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• 2002

Fish distribution characteristics are essential to assess and estimate fisheries resources in a particular area. The primary goal of this study is to determine the distribution characteristics by the bottom trawling in the Yellow Sea west of South Korea. The surveys were carried out between 33$^{\circ}$00'N~37$^{\circ}$00'N latitude and 124$^{\circ}$00'E~126$^{\circ}$00'E longitude at EEZ(Exclusive Economic Zone) of Korea in Yellow Sea on May and August, 1999 and April, 2000. The ships used in this survey were the R/V Chung-kyeong(G/T 300) and R/V Dong-baek(G/T 1,050) of Yeosu National University. The results obtained can be summarized as follows 1. From the trawl data the fisheries resources are seriously decreasing through most of the species(about more 50%) have been appeared only one time at the bottom trawl on April, 2000. The total fish species caught by the trawl net during the 3 times survey were 106 species and a few species(dominant species) of these occupied 50~90% of the quantity of the total quantity by number or by weight. Among the dominant species the tanaka's snailfish was recorded to be the most dominant species in the survey area. The fish species in the Yellow Sea were clustered according to the regions. They clustered in two or three partes to the south-north direction in the spring season and clustered in two parts to the on-off shore direction of the shore in the summer season. Most of the fish caught at the the trawl net with cover-net(30.3mm) were small sized. They were shorter than 15 cm in length and the extruding rate of the cod-end which was 60mm mesh size ranges about 90%. 2. The densities of the number and weight per unit volume derived from the total catches sampled in April, 2000 survey were $1532.2{\times}10^{-6}fish/m^3$ and $39.55{\times}10^{-6}kg/m^3$, respectively. 3. The density variation of fish population between 1999 and 2000 showed a slight tendency to increase.

• Journal of The Korean Society of Grassland and Forage Science
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• v.4 no.1
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• pp.51-61
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• 1983

This experiment was carried out to determine the effects of different seeding rates of Italian ryegrass (Lolium multiflorum) and cutting frequency on the dry matter yield botanical composition of pasture mixtures in first harvest year. The experimental design was a split-plot design with three replication. The main plots were two seeding rates of Italian ryegrass at 0.3 and 1.0kg per 10a and the sub-plots were 3, 4, and 5 cutting frequency. The experiment was undertaken over a period 12 months from September 1981 to August 1982. The results obtained are summarized as follows: 1. The different seeding rates of Italian ryegrass had no effect on total day matter yield. 2. Over the experimental period, the total dry matter yield of pasture mixtures was increased with increasing the cutting frequency, but there was no significant. 3. It was found that dry matter yield of weeds clearly decreased with the high seeding rate of Italian ryegrass over the experimental period. 4. The high seeding rate of Italian ryegrass showed the trend toward the high yield of Italian ryegrass, and the low yield of orchardgrass and ladino clover. 5. At the early stage of the experiment, the botanical compositions of orchardgrass and ladino clover were decreased with the high seeding rate of Italian ryegrass. But at the final stage they were not influenced by the seeding rates of Italian ryegrass. From the above results it is suggested that the high seeding rate of Italian ryegrass give a good effect on the early forage yield and weed control, and the high cutting frequency maintain desirable botancial composition of orchardgrass and ladino clover in the pasture mixtures with Italian ryegrass.

• Clinical and Experimental Pediatrics
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• v.50 no.9
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• pp.905-911
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• 2007

Purpose : Ghrelin, being secreted from the stomach, stimulates growth hormone secretion and controls energy homeostasis by increasing appetite. Leptin, being secreted from the adipocytes, controls weight and energy homeostasis by decreasing appetite. Leptin concentration is reported to increase after childhood cancer therapy. This study was aimed to compare ghrelin and leptin concentrations in normal children and children who received cancer therapy. Methods : We enrolled forty-three patients who were diagnosed with cancer and received radiotherapy or chemotherapy during Dec. 2004 through Dec. 2005 in St. Marys hospital and Kangnam St. Marys hospital. Forty-five healthy children were selected as a control group whose age, gender, weight and height were similar to those of cancer group. The serum leptin and ghrelin concentrations were also measured by radioimmunoassay. Results : The cancer group showed higher BMI and leptin concentrations. The control group showed higher concentrations of ghrelin. Both control and cancer groups revealed positive correlations between leptin concentrations and BMI. Ghrelin concentrations in the control group showed negative correlations with age, height, weight and BMI but no significant correlation was found in the cancer group. All the parameters in the group treated with chemotherapy only were not different from those in the group treated with chemotherapy and irradiation. But the level of ghrelin in the acute myeloid leukemia group was much higher than those in the acute lymphoblastic leukemia group. Conclusion : Patients with pediatric cancer treatment have presented higher BMI and leptin concentrations but lower ghrelin concentrations than those in healthy children. Because of the relatively short duration and cross sectional method of the study, however, further long term and prospective study will be required in the future.