• Geophysics and Geophysical Exploration
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• v.1 no.2
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• pp.110-115
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• 1998

Self-potential, VLF-EM and dipole-dipole resistivity methods have been widely used for exploration of conductive sulfide ore deposit, because of the convenience and low cost of field work and the reliability of their results. The geophysical responses for vein-type sulfide outcrop of Changkoom mine located in Bukwi-Myon, Jinan-Gun, Chollabuk-Do were investigated and compared with its drilling results. The geology around the survey area is composed of acidic volcanics and sediments of Yuchon Group. And sulfides bearing pyrite, pyrrotite, galena etc. are deposited in disseminated or vein type within acidic volcanics. Typical geophysical responses were detected from the above vein type ore body, respectively. From the shape and extent of S.P. anomaly, ore body is dipping westward and extending about 50 m. It is detected that the VLF EM response matching the outline of ore zone is considered as indication of dyke dipping westward. And also resistivity response indicating conductive dipping dyke is detected. From drilling results for outcrop and geophysical anomalies, the shape of ore body is vein type dipping about $70^{\circ}W$ and extending about 50 m.

• The Journal of the Korea Contents Association
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• v.16 no.12
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• pp.233-243
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• 2016

The movie offers a chance to observe the social signifier and the sensitivity of audiences who feel sympathy with the tragic history of crown prince Sado. While watching the movie, the audience halts between ideas whether to go back to "primary ego", or to play the unconscious hypocrisy or the ingrained social behavior which is to resolve the internal conflicts while they face two contrary opinions; one is the obedient subject to obey fatherness, as a symbol of historic value and convention in a society, and the other is the resistant body to break the bond of convention. The audience may feel some ambivalent feelings of the moral values between the paternal authority and the existential philosophical value of 'self'. This study will observe the audience's response of Sado toward the moral norms of the society when they face the signifier of father in the movie with experience the conflict between their resistant ego and madness. Also the study will discuss that the social landscape such as norms, order, and legal system is ever-changing and open to be subverted by the future even though audience hope that the present moral value with which we are content ever-last.

• Journal of Ginseng Research
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• v.22 no.1
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• pp.22-31
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• 1998

Antiulcer effects of ginseng saponin, acidic polysaccharide and methanol extract of Panax ginseng in the patients and experimental animals were reported. Postulated action mechanisms of ginseng were histamine-Ht receptor blocking and increasing gastric blood flow In the present study, the effect of ginsenosides, the biologically active glycosides of ginseng, on gastric acid secretion was examined using gastric cells isolated from human and rabbit gastric mucosa. Ginseng saponin, ginsenoside $Rb_1$, $Rb_2$, $Rg_1$ and $Rh_2$ were tested in unstimulated as well as stimulated gastric cells. Histamine ($10^4$M) and 3-isobutyl-1-methylxanthine ($10^4$M) were used as secretagogues. To investigate the mechanism of ginsenosides on acid secretion, the levels of cAMP and cGMP were monitored in gastric cells. As a result, high concerltration(1mg/ml) of ginseng saponin showed 73-75% of stimulated acid secretion in control gastric cells. However, ginseng saponin had no effect on unstimulated acid secretion and the levels of cGMP and cAMP in gastric cells. Ginsenoside $Rb_1$, $Rb_2$ and $Rh_2$ significantly inhibited stimulated acid secretion. Gastric cGMP levels were increased by all ginsenosides tested while cAMP levels were increased by all ginsenosides in unstimulated state of gastric cells, but increased by ginsenosides ginsenoside $Rg_1$ and $Rh_2$in stimulated state of gastric cells. The results suggest that inhibition of ginseng saponin on gastric acid secretion represents a complex effect of individual ginsenosides, which produce a range of effect on acid secretion. The inhibition site of ginseng saponin on stimulated acid secretion is postulated as post cAMP levels in acid secretary pathway such as protein phosphorylation or proton pump. Nitric oxide may not be involved in the inhibitory effect of ginseng saponin on stimulated acid secretion.

• Journal of Gastric Cancer
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• v.3 no.2
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• pp.88-92
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• 2003

Purpose: Mounting evidence suggests that alterations of Akt/protein kinase B (PKB) play an important role in tumorigenesis. Phosphorylated Akt regulates many of the key effector molecules involved in apoptosis, angiogenesis, and cell-cycle progression during tumorigenesis. The expression of phosphorylated Akt has been described in some human malignancies, but not in primary human gastric cancer. The purpose of this study was to explore the expression status of phosphorylated Akt protein in gastric carcinomas. Materials and Methods: In the current study, we analyzed the expression of phosphorylated Akt protein in 60 advanced gastric adenocarcinomas by using immunohistochemistry and a tissue microarray approach. Results: Immunopositivity (defined as $\geq\30\%$) was observed for the phosphorylated Akt in 42 ($70\%$) of the 60 cancers. Normal gastric mucosal cells showed no or weak expression of phosphorylated Akt protein. Conclusion: Taken together, these results indicate that Akt is frequently activated in gastric adenocarcinoma cells and suggest that phosphorylayed Akt may play a role in the development of human gastric adenocarcinomas.

• Journal of Gastric Cancer
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• v.3 no.2
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• pp.75-79
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• 2003

Purpose: Evidence exists that dysregulation of apoptosis is involved in the pathogenesis of cancer development. The Bcl-$x_{L}$/Bcl-2-associated death promoter (BAD), a member of the Bcl-2 family, is a critical regulatory component of the intrinsic cell-death pathway that exerts its pro-apoptotic effect upon heterodimerization with anti-apoptotic proteins Bcl-2 and Bcl-$X_{L}$. Expression of the BAD protein has been reported in several cancer types, but not in stomach cancer. The aim of this study was to explore the expression status of the BAD protein in gastric carcinomas. Materials and Methods: In the current study, we analyzed the expression of the BAD protein in 60 advanced gastric adenocarcinomas by using immunohistochemistry and a tissue microarray approach. Results: Immunopositivity (defined as $\geq\30\%$) was observed for the BAD protein in 57 ($95\%$) of the 60 cancers. Normal gastric mucosal cells showed weaker expressions of the BAD protein than gastric carcinomas. Conclusion: Taken together, these results suggest that stomach cancer cells in vivo may need BAD protein expression for apoptosis. Also, the higher expression of the BAD protein in stomach cancer cells than in normal gastric mucosal cells suggests that apoptosis might be easily triggered in susceptible stomach cancer cells, thereby producing selective pressure to make more apoptosis-resistant cells during tumor development.

• Journal of Gastric Cancer
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• v.7 no.3
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• pp.174-179
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• 2007

The survival of patients with gastric cancer is improved by early diagnosis and surgical treatment. However, there is no established treatment for locally recurrent cancer or cancer arising at an anastomotic site after total gastrectomy; further, most surgeons are reluctant to resect this type of cancer because of frequent systemic metastasis and there are few competent surgeons who have the skill to perform such an operation. We have experienced recurrent cancer at an anastomotic site after total gastrectomy: one patient had recurrent cancer and two patients had metachronous cancer. All these patients were operated on and the patients were discharged without any complications. All of them are alive at the time of this report. In some cases, good results could be expected for operating on recurrent cancer of an anastomotic site after previous total gastrectomy. So, we present here our experience along with a review of literatures.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.18 no.11
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• pp.2745-2752
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• 2014

In recent years, Transport Demand Management has been conducted for the efficient management of transport. In ITS applications in particular, the prerequisite is accurate and reliable positioning. However, the major problems are satellite signal outage, and multipath. This paper proposes that outage and multipath measurement can be detected and estimated using elevation angle and signal to noise ratio data association relation in stand-alone GPS. In order to verify the performance of the proposed method, it is then evaluated by the car test. the evaluation test environment has low accuracy and unreliable positioning because of signal outage or multipath such as steep hill and high buildings. In the evaluation test result, 918times abnormal signal occurred and it was confirmed that the proposed method showed more improved 9.48m(RMS) horizontal positioning error than without proposed method.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2004.05b
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• pp.545-547
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• 2004

Currently possibility of the change of seal computer it increases geometrical progression and the general individuals the knowledge which is special regarding the ip are using the flow child blood which it Provides without from the isp enterprise. But most of the case peon of the school which uses the fixation child blood or the company because is not the knowledge against a TCP/IP address is not oneself at deliberation or real income and it will use the TCP/IP address of the different user and the network whole it will paralyze, the original user will not be able to use the network and it makes. With information where address information where the network administrator present time after data base anger one uses address information of the civil official objective personal computers and network systems of the watch inside in the dictionary is stored will be same from the dissertation which it sees hereupon and the web which it will yell it leads and packet it detects, the use of the TCP/IP address which goes wrong in the user and it notifies the method which is the possibility of closing the paralysis of the network system which it follows in the IP address fringe land due to a deliberation or a real income to sleep it presents it does.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2006.05a
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• pp.664-667
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• 2006

This study are aimed at make more efficient student consultation with develop DCERS, It based on many teachers counsel experience from consult students. This system built of administrator module and user module. And also this system designed that help effectively counsel guidance through several leacher's experience who has counsel guidance. User module is adjust io teachers example, so we can user counsel specifics search, input, PDS. And administrator module offer function that counsel guidance data manager and member manager. After this system apply to leachers who is at the front. And I make an analyze effect and present result.

• Proceedings of the Korea Water Resources Association Conference
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• 2017.05a
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• pp.386-386
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• 2017

지하수 해석을 위해 3차원 수치해석 모형이 적용되고 있으나, 다양한 매개변수를 명확히 적용하기에는 한계가 있다. 특히, 수리전도도는 지층의 투수성정도를 나타내는 계수로 지하수 분석에 매우 중요한 매개변수이다. 신뢰성의 확보를 위해 양수시험을 통해 산출된 결과를 이용하고 있으나 소수관정의 시험결과를 유역의 대푯값으로 적용하기에 불확실도가 매우 높고, 수위변화가 독특한 지역의 정확한 수리특성을 적용하기에 한계가 있다. 이 연구에서는 수리전도도 특성을 해석하기 위하여 3차원 수치해석모형을 적용하였으며, 모델보정 방법 중 Regularization(정규화)라고 불리는 Pilot point 기법을 사용하였다. 제주도와 같이 수리전도도 값이 지역별로 차이가 크고 동일 유역 내에도 다른 지질구조를 보이는 등 동일 매질에서 동일 투수성을 보이지 않는 다양함으로 실측값들을 적용하기에 어려운 곳에서 정규화라는 보정방법은 최적화된 방법이다. 지하수위는 중제주유역 내 위치한 12개소 수위관측정의 2016년 연평균수위를 적용하였다. 미계측지역은 제주도 등수위선자료를 이용하여 DEM을 구축하였으며, 임의지점 17개소를 선정하여 대표수위로 적용하였다. 중제주유역의 평균 수리전도도는 82.90 m/day로 분석되었으며, 유역의 동측 하류부는 최대 1,745 m/day로 비교적 큰 결과가 산출되었다. 유역의 중앙에 위치하는 OR관측정을 기준으로 동 서지역의 지하수위를 검토한 결과 서측은 지형구배에 따라 지하수위가 형성하고 있으나, 동측의 경우 상 하류의 표고차가 30m이상 발생되지만 지하수위는 유사한 형태를 보이고 있다. 지하수 흐름에 해석되는 Darcy의 방정식은 수리전도도와 동수경사는 반비례관계를 나타내며, 이 이론에 의해 상 하류 지하수위가 유사하게 형성되는 동측지역은 국부적으로 수리전도도가 높게 형성되는 것으로 확인되었다. 실무에서는 유역경계에 따라 평균화된 매개변수가 적용되므로 명확한 지하수 해석이 어렵고, 수리전도도와 같이 지역적 편차가 심한 매개변수는 다양한 연구를 통해 적용성검토가 수행되어야 한다.